Molecular Mechanisms of Cell Reprogramming and Differentiation
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 184
Editor
Interests: cell differentiation; exosome; epigenetic; oncosomes; cancer; exosomal cancer evolution; cancer cell reprogramming; tissue regeneration; cell survival; cellular senescence; aging prevention
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cell reprogramming and differentiation are fundamental biological processes that govern development, tissue homeostasis, regeneration, and disease progression. Recent advances in molecular biology, epigenetics, single-cell technologies, and systems biology have greatly improved our understanding of how embryogenesis develops from a molecular point of view and how cell identity is established, maintained, and altered. Elucidating the molecular mechanisms underlying these processes is essential for developing innovative strategies in regenerative medicine, cancer biology, stem cell research, and personalized therapeutics.
This Special Issue aims to provide a focused platform for the publication of high-quality original research articles, including basic, translational, and clinical studies and comprehensive reviews addressing the molecular pathways, regulatory networks, and epigenetic mechanisms involved in cell fate determination, cellular plasticity, reprogramming, and lineage-specific differentiation. Topics of interest include transcriptional regulation, chromatin remodeling, non-coding RNAs, signaling pathways, stem cell dynamics, induced pluripotency, transdifferentiation, and disease-associated dysregulation of differentiation programs and the use of stem cell differentiation factors.
We warmly invite you to participate, and we look forward to receiving your contributions.
Prof. Dr. Pier Mario Biava
Guest Editor
Stefano Ciaurelli
Guest Editor Assistant

Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- stem cell differentiating stage factors
- cell reprogramming
- cell differentiation
- stem cells
- epigenetic regulation
- cellular plasticity
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