Musculoskeletal Diseases: From Molecular Basis to Therapy—3rd Edition
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 864
Special Issue Editors
2. Orthopedics and Orthopedic Oncology, Department of Surgery, Oncology and Gastroenterology (DiSCOG), University of Padova, 35129 Padova, Italy
Interests: inflammation; molecular biology; cell biology; osteoarthritis; cartilage; musculoskeletal diseases; bone cancer; synovium; infrapatellar fat pad; chondrosarcoma
Special Issues, Collections and Topics in MDPI journals
2. Orthopedics and Orthopedic Oncology, Department of Surgery, Oncology and Gastroenterology (DiSCOG), University-Hospital of Padova, 35128 Padova, Italy
Interests: musculoskeletal diseases; bone cancer; chondrosarcoma; osteoarthritis; inflammation; joint tissues; aging; molecular biology; cell biology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Musculoskeletal diseases comprise numerous different disorders (more than 150 conditions) that affect the locomotor system (joints, bones, muscles, cartilage, menisci, and tendon tissues) and are associated with significant morbidity and disability. A recent analysis of the Global Burden of Disease estimated that approximately 1.71 billion people globally have musculoskeletal conditions. The number of affected individuals is expected to grow as the population ages. Thus, a better understanding of the etiology and new and more effective therapeutic treatments are needed. The purpose of this Special Issue is to report advances in pathophysiological mechanisms, predictive biomarkers, and preclinical therapeutic approaches in musculoskeletal disorders, with a particular focus on bone cancers and osteoarthritis.
Authors are invited to contribute to this Special Issue by sharing original research articles and comprehensive reviews.
Possible topics include, but are not limited to, the following:
- Pathophysiological studies related to musculoskeletal diseases;
- Molecular, biochemical, and biomechanical mechanisms involved in the etiology and progression of musculoskeletal disorders;
- The identification of biomarkers that are useful for early diagnosis and/or predictive of prognosis;
- Preclinical research into potential drugs and cell-based strategies for the treatment of musculoskeletal disorders.
Dr. Elisa Belluzzi
Dr. Assunta Pozzuoli
Guest Editors
Manuscript Submission Information
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Keywords
- musculoskeletal diseases
- bone cancer
- soft tissue cancer
- bone metastasis
- natural compounds
- anticancer drugs
- osteoarthritis
- joint tissues
- biomarkers
- inflammation
- microRNAs
- exosomes
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