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Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Neonatal Disease: From Pathophysiology to Current and Emerging Therapeutic Approaches (3rd Edition)
edited by
submission deadline 30 Jun 2026 | Viewed by 59 | Submission Open
Keywords: fetal therapy; neonatal diseases; pathophysiology; innovative therapeutic approaches
(This special issue belongs to the Section Cell Biology and Pathology)
Intraoperative Neurophysiology: New Perspectives and Clinical Applications
edited by Riccardo Budai and Giada Pauletto
submission deadline 30 Jun 2026 | Viewed by 58 | Submission Open
Keywords: IOM (intra operative monitoring); MEP (motor evoked potentials); SEP (somatosensory evoked potentials); BAEP (brainstem acoustic evoked potentials); VEP (visual evoked potentials); EMG (electromyography); EEG (electroencephalography); EcoG (electrocorticography); epilepsy; cerebral tumors
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Viral Hepatitis: From Pathophysiology to Therapeutic Approaches submission deadline 30 Jun 2026 | Viewed by 58 | Submission Open
Keywords: viral hepatitis; hepatotropic viruses; viral persistence; immunomodulatory; antiviral resistance
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Bowel Cancer: From Early Diagnosis to Personalized Treatment Strategies
edited by Maximos Frountzas
submission deadline 30 Jun 2026 | Viewed by 58 | Submission Open
Keywords: colorectal cancer; precision oncology; liquid biopsy; circulating tumor DNA (ctDNA); molecular biomarkers; radiomics and radiogenomics; artificial intelligence in oncology; tumor microenvironment; personalized therapy; early cancer detection
(This special issue belongs to the Section Cancer Biology and Oncology)
Translational Immunology in Inflammatory Bowel Diseases: From Mechanisms to Precision Medicine
edited by Fotios S. Fousekis
submission deadline 30 Jun 2026 | Viewed by 58 | Submission Open
Keywords: IBD; immunology; cytokine
(This special issue belongs to the Section Molecular and Translational Medicine)
Integration of Multi-Omics Analysis and Biomaterial Innovation in Tissue Repair and Regeneration
edited by
submission deadline 30 Jun 2026 | Viewed by 55 | Submission Open
Keywords: biomaterial innovation; multi-omics integration; tissue engineering; regenerative medicine; personalized medicine; translational research
(This special issue belongs to the Section Biomedical Engineering and Materials)
The Molecular Basis of Brain Diseases
edited by
submission deadline 30 Jun 2026 | Viewed by 55 | Submission Open
Keywords: molecular biomarkers; brain tumors; neurodegenerative diseases; gene regulation; immunotherapy; neuroinflammation
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
New Advances of Biomedical Engineering and Materials
edited by Mei-Jung Chen, and
submission deadline 30 Jun 2026 | Viewed by 54 | Submission Open
Keywords: tissue engineering; artificial intelligent biocompatible materials; cell therapy; drug delivery system
(This special issue belongs to the Section Biomedical Engineering and Materials)
Advances in the Diagnosis and Management of Liver Cirrhosis and Portal Hypertension
edited by Xiaoze Wang
submission deadline 30 Jun 2026 | Viewed by 54 | Submission Open
Keywords: liver cirrhosis; portal hypertension; hepatic fibrosis; vascular remodeling; sinusoidal endothelial dysfunction; bile acid signaling; gut– liver axis; non-invasive diagnostics; artificial intelligence
(This special issue belongs to the Section Molecular and Translational Medicine)
Technologies and Applications of Genome Editing
edited by
submission deadline 30 Jun 2026 | Viewed by 53 | Submission Open
Keywords: genome manipulation; CRISPR/Cas systems; preclinical animal models; translational research; editing efficiency; base editing and prime editing; genetically engineered mouse models (GEMMs); virus-like particles (VLPs)
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Molecular Mechanisms and Emerging Therapies in Human Skeletal Disorders
edited by Sudeep Gautam
submission deadline 30 Jun 2026 | Viewed by 52 | Submission Open
Keywords: skeletal disorders; genetic bone diseases; metabolic bone disease; rare skeletal dysplasias; extracellular matrix biology; CRISPR genome editing; genetically modified mouse models; gene therapy; AAV-based therapeutics; RNA therapeutics; musculoskeletal regeneration
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in the Pathogenesis and Therapeutics of Pulmonary Disease
edited by Sara Manti and
submission deadline 30 Jun 2026 | Viewed by 51 | Submission Open
Keywords: pulmonary diseases; pathogenesis; therapeutic targets; drug discovery; respiratory inflammation; precision medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Decoding Retinal Degeneration
edited by
submission deadline 30 Jun 2026 | Viewed by 49 | Submission Open
Keywords: retinal degeneration; inherited retinal diseases; retinitis pigmentosa; stargardt disease; age-related macular degeneration; photoreceptor degeneration; gene therapy; RNA-based therapies; epigenetic regulation; transcriptomics/proteomics; retinal biomarkers; molecular pathways of neurodegeneration; oxidative stress and inflammation; mitochondrial dysfunction; retinal microglia and neuroinflammation; retinal vasculopathy; stem cell therapy; retinal drug delivery; nanotechnology in ophthalmology; advanced retinal imaging (OCT; OCTA; FAF); artificial intelligence in retinal disease; precision and personalized ophthalmology; translational research in ophthalmology
(This special issue belongs to the Section Molecular and Translational Medicine)
Drug Development in Gastrointestinal Disorders
edited by and Stoaynka Atanasova Nikolova
submission deadline 30 Jun 2026 | Viewed by 45 | Submission Open
Keywords: inflammatory bowel disease (IBD); crohn's disease; gastrointestinal disorders; biologics; small-molecule inhibitors; drug delivery system; therapeutic target; drug resistance; biomarker; multitarget therapy; nanoparticles
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
New Advances in Heart Diseases
edited by
submission deadline 30 Jun 2026 | Viewed by 43 | Submission Open
Keywords: biologics; heart diseases; regenerative medicine; gene therapy; stem cell therapy; monoclonal antibodies; RNA therapeutics; precision cardiology; cardiovascular regeneration; inflammatory modulation
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Burn Research: Therapeutic Innovations
edited by
submission deadline 30 Jun 2026 | Viewed by 43 | Submission Open
Keywords: burn wound healing; regenerative medicine; tissue engineering; infection control in burns; scar prevention
(This special issue belongs to the Section Biomedical Engineering and Materials)
Neurological Complications in Oncology: From Pathogenesis to Therapy
edited by Pierfranco Conte
submission deadline 30 Jun 2026 | Viewed by 42 | Submission Open
Keywords: neurological complications; neuro-oncology; neurotoxicity; chemotherapy-induced cognitive impairment; cancer-related neuropathy; neuroprotection; neuroimaging
(This special issue belongs to the Section Cancer Biology and Oncology)
The Role of Endothelial Cells in Human Health and Diseases
edited by Adama Sidibé
submission deadline 30 Jun 2026 | Viewed by 32 | Submission Open
Keywords: endothelial cells; angiocrine signaling; endothelial dysfunction; fibrosis; tumor microenvironment; cardiovascular disease; angiogenesis; vascular homeostasis; mechanotransduction; metabolic regulation
(This special issue belongs to the Section Cell Biology and Pathology)
Technology and Applications of Genome Editing in Biomedicine
edited by Guanhua Xun
submission deadline 30 Jun 2026 | Viewed by 22 | Submission Open
Keywords: RNA therapeutics; mRNA vaccines; antisense oligonucleotides (ASOs); siRNA and miRNA therapeutics; nucleic acid modifications; chemical stability and delivery; gene regulation therapy; precision medicine; CRISPR/Cas systems; guide RNA (gRNA); genome editing
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Mechanisms and Management of Chronic Pain: Nociceptive, Neuropathic, and Nociplastic Perspectives submission deadline 1 Jul 2026 | Viewed by 75 | Submission Open
Keywords: pain; nociplastic; sensitization; neuropathic; mechanisms; treatment; classification
(This special issue belongs to the Section Molecular and Translational Medicine)
Exploring Human Diseases Through Genomic and Genetic Analyses
edited by Fernando Regateiro and
submission deadline 15 Jul 2026 | 4 articles | Viewed by 5505 | Submission Open
Keywords: genomic and genetic analyses; genomic medicine; personalized medicine; technologies and testing methods; complex diseases; monogenic diseases; pharmacogenomics
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
The Role of Iron in Human Diseases
edited by Margherita Correnti
submission deadline 15 Jul 2026 | 3 articles | Viewed by 4333 | Submission Open
Keywords: iron metabolism; iron dysregulation; diseases; iron deficiency; iron overload
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Animal Models of Human Pathology: Revision, Relevance and Refinements (4th Edition)
edited by
submission deadline 15 Jul 2026 | 4 articles | Viewed by 2216 | Submission Open
Keywords: animal models; biomarkers; human disease; pathology; translation; mechanisms; nephrology; gastroenterology; urology; neuroscience; cancer; experimental design; reproducibility; refinements
(This special issue belongs to the Section Molecular and Translational Medicine)
Photodynamic Therapy (4th Edition)
edited by
submission deadline 15 Jul 2026 | Viewed by 330 | Submission Open
Keywords: antimicrobial photodynamic treatment; chronic wounds; inflammatory dermatoses; photobiology photochemistry; photochemotherapy; photosensitizing agents; skin cancer; oral mucosa
(This special issue belongs to the Section Immunology and Immunotherapy)
Extracellular Matrix in Health and Disorders (2nd Edition)
edited by
submission deadline 15 Jul 2026 | Viewed by 194 | Submission Open
Keywords: ECM; connective tissue; healthy tissues; pathological tissues; imaging; drug targets; markers; dermis; bone; tendon
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancing Pharmacogenetics and Pharmacogenomics in Pre-Clinical Research: Unveiling New Avenues for Precision Medicine
edited by and
submission deadline 30 Jul 2026 | 1 articles | Viewed by 925 | Submission Open
Keywords: pharmacogenetics; pharmacogenomics; precision medicine; individualized medicine
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Immune Checkpoint Blockade and Beyond: Next-Generation Cancer Immunotherapies
edited by Wenxuan Zhang
submission deadline 30 Jul 2026 | Viewed by 54 | Submission Open
Keywords: immune checkpoint blockade; cancer immunotherapy; tumor microenvironment; immune resistance; PD-1/PD-L1; CTLA-4; combinatorial therapy; immunometabolism; biomarkers; translational oncology
(This special issue belongs to the Section Immunology and Immunotherapy)
Ovarian Physiology and Reproduction
edited by Atefeh Najafi
submission deadline 31 Jul 2026 | 6 articles | Viewed by 18790 | Submission Open
Keywords: ovarian physiology; female fertility; folliculogenesis; oocyte; hormonal regulation; endocrine disruptors; ovarian aging; genetic modifications; environmental factors and female fertility; female reproductive health and disorders
(This special issue belongs to the Section Molecular and Translational Medicine)
Traumatic CNS Injury: From Bench to Bedside (2nd Edition)
edited by
submission deadline 31 Jul 2026 | 4 articles | Viewed by 14838 | Submission Open
Keywords: neurotrauma; traumatic brain injury; translational science; bench to bedside; neuroprotection
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Novel Biomarker and Treatments for Diabetic Neuropathy
edited by Arun V. Krishnan and Tushar Issar
submission deadline 31 Jul 2026 | 6 articles | Viewed by 14815 | Submission Open
Keywords: diabetic peripheral neuropathy; type 1 diabetes; type 2 diabetes; glucagon-like peptide-1 receptor agonists; metabolic syndrome; in vivo corneal confocal microscopy; nerve ultrasonography; obesity; exercise
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Biological Therapies for Asthma: Targeting Type 1 and Type 2 Inflammation
edited by Mohammad Irshad Reza and Nilesh Sudhakar Ambhore
submission deadline 31 Jul 2026 | 2 articles | Viewed by 11707 | Submission Open
Keywords: asthma endotypes; type 1 inflammation; type 2 inflammation; biological therapies for asthma; non-type 2 asthma; cytokine pathways in asthma; precision medicine in asthma; inflammatory biomarkers in asthma; Th1/Th2 immune responses
(This special issue belongs to the Section Molecular and Translational Medicine)
Neurodegeneration No More: Cutting-Edge Technologies and Therapies in the Evolution of Neurodegenerative Disease Management—2nd Edition submission deadline 31 Jul 2026 | 7 articles | Viewed by 10143 | Submission Open
Keywords: Alzheimer’ s disease; frontotemporal lobar degeneration; Parkinson’ s disease; aging decline; mild cognitive impairment; multiple sclerosis; stroke; acquired brain damage; altered cognitive processes; brain functional impairment; neurocognitive disorders; cognitive; behavioral; and functional disorders; acquired trauma; brain plasticity and connectivity; non-invasive brain stimulation; diagnosis and treatment; functional evidence of altered cognition and connectivity; blood-based biomarkers; disease heterogeneity; prognosis; protein aggregation; inflammation; oxidative stress; medicinal plants; phytocompounds
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Animal Models of Neurological Disorders: Where Are We Now? (3rd Edition)
edited by
submission deadline 31 Jul 2026 | 3 articles | Viewed by 6815 | Submission Open
Keywords: animal model of neurological disorders; Parkinson’ s disease; Alzheimer’ s disease; epilepsy; seizures; Huntington’ s disease; schizophrenia
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advances in Reproductive Medicine and Health
edited by Athanasios Zikopoulos, Sofoklis Stavros and
submission deadline 31 Jul 2026 | 2 articles | Viewed by 6178 | Submission Open
Keywords: reproductive medicine; assisted reproductive technology; fertility preservation; IVF; early pregnancy; miscarriages; proteomics; metabolomics; transcriptomics; infertility; bioethics; cryopreservation; personalized medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Oxidative Stress in Health and Disease
edited by Federica Mannino
submission deadline 31 Jul 2026 | 1 articles | Viewed by 5256 | Submission Open
Keywords: oxidative stress; inflammation; human diseases; apoptosis; peroxidation; DNA damage; mitochondria
(This special issue belongs to the Section Cell Biology and Pathology)
Breast Cancer Research: Charting Future Directions submission deadline 31 Jul 2026 | 5 articles | Viewed by 3913 | Submission Open
Keywords: personalized medicine; biomarkers for early detection; immunotherapy; patient-reported outcomes
(This special issue belongs to the Section Cancer Biology and Oncology)
Recent Advances in Gastrointestinal Cancers: From Microbiota Modulation to New Therapeutic Approaches—2nd Edition
edited by
submission deadline 31 Jul 2026 | 3 articles | Viewed by 3892 | Submission Open
Keywords: gastrointestinal cancers; microbiota; anticancer therapy; immunotherapy; precision medicine
(This special issue belongs to the Section Cancer Biology and Oncology)
Zebrafish Models for Development and Disease—5th Edition
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 3540 | Submission Open
Keywords: disease model; drug screening model; teratogen screening; toxicological screening; neuroscience; behavior; developmental biology
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Extracellular Vesicles in Therapeutics submission deadline 31 Jul 2026 | 1 articles | Viewed by 3509 | Submission Open
Keywords: extracellular vesicles (EVs); exosomes; regenerative medicine; immunotherapy; nanocarriers; biomarkers
(This special issue belongs to the Section Immunology and Immunotherapy)
Current Perspectives on Gynecologic Cancers
edited by
submission deadline 31 Jul 2026 | 3 articles | Viewed by 3469 | Submission Open
Keywords: gynecology; genetics; biology; bioinformatics; review; predictive model; artificial intelligence
(This special issue belongs to the Section Cancer Biology and Oncology)
Diagnosis, Pathogenesis and Treatment of CNS Tumors (2nd Edition)
edited by
submission deadline 31 Jul 2026 | 3 articles | Viewed by 2563 | Submission Open
Keywords: CNS tumors; diagnosis; pathogenesis; treatment; prognosis; molecular markers
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research on Diabetic Retinopathy
edited by Stamatios Lampsas
submission deadline 31 Jul 2026 | 2 articles | Viewed by 1938 | Submission Open
Keywords: diebetic retinopathy; retinal diseases; novel treatment strategies; progression; pathogenetic mechanisms; non-proliferative diabetic retinopathy; proliferative diabetic retinopathy
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Molecular and Translational Medicine in Japan
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1819 | Submission Open
Keywords: molecular and translational research; targeting inflammatory cytokines; targeted drugs; skin diseases; basic mechanisms; novel therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Heart–Brain Axis
edited by Teresa Soda
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1749 | Submission Open
Keywords: heart– brain axis; neurocardiology; autonomic nervous system; neuroinflammation; cardiac– cerebral syndromes; psychocardiology; calcium signaling; synaptic plasticity; ion transport; translational neuroscience
(This special issue belongs to the Section Molecular and Translational Medicine)
Strategies for Anticancer in p53 Mutated Cancers
edited by and
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1517 | Submission Open
Keywords: p53; p63; p73; tumor suppressor gene; microRNA; long non-coding RNA; protein degradation; heat shock proteins; mutation; oncology
(This special issue belongs to the Section Cancer Biology and Oncology)
Platelets in Human Health and Diseases
edited by Joanna Sikora
submission deadline 31 Jul 2026 | 2 articles | Viewed by 1203 | Submission Open
Keywords: platelet; hemostasis; thrombosis; antiplatelet drugs; inflammation; cancer; cardiovascular diseases
(This special issue belongs to the Section Cell Biology and Pathology)
New Insights in Reproductive Health and Disease
edited by
submission deadline 31 Jul 2026 | 2 articles | Viewed by 1142 | Submission Open
Keywords: reproductive health; artificial intelligence; fertility preservation; stem cells; gene therapy; materials; meiosis; DNA double-strand break; ovarian dysfunction; nanomedicine; pregnancy complications
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Biology of Cancer: From Biomarkers to Targeted Therapy
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 611 | Submission Open
Keywords: molecular biology; carcinogenesis; cancer; biomarkers; prognostic markers; predictive markers; precision medicine; targeted therapy
(This special issue belongs to the Section Cell Biology and Pathology)
The Latest Advancements in Tumor Drug Delivery Systems
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 576 | Submission Open
Keywords: tumor targeting; gene delivery; biomemetic drug delivery; cancer-targeting nanorobot; specific cancer cell targeting; antitumor immunotherapy; cancer nanovaccine; tumor-suppressing nanoenzyme
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Clinical Advances in Hepatocellular Carcinoma
edited by Mohamed A. Abd El Aziz
submission deadline 31 Jul 2026 | 1 articles | Viewed by 542 | Submission Open
Keywords: hepatocellular cancer; liver cirrhosis; chemotherapy; immunotherapy; radiofrequency ablation; microwave ablation
(This special issue belongs to the Section Cancer Biology and Oncology)
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