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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Fatty Acid Metabolism as the Markers of Civilization Diseases (3rd Edition)

edited by

Arleta Drozd

submission deadline 31 Jan 2026 | Viewed by 162 | Submission Open

Keywords: fatty acids; lipidomics; biochemistry; infalmmation; pathophysiological mechanisms; lipid mediators; gut microbiota; NAFLD/NASH; insulin resistance; type 2 diabetes; endocine diseases; cardiovascular diseases

(This special issue belongs to the Section Molecular and Translational Medicine)

Nervous System Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by Natalia Rozas and Cameron Jeter

submission deadline 31 Jan 2026 | Viewed by 124 | Submission Open

Keywords: neurodegenerative diseases; neuromuscular diseases; autoimmune diseases of the nervous system; brain diseases; neuroinflammatory diseases; neuromuscular diseases; trauma of the nervous system

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Cardiovascular Diseases: Pathophysiological Insights, Therapeutic Strategies and Future Directions

edited by

Azizah Ugusman

, Wan Amir Nizam Wan Ahmad and Dharmani Devi Murugan

submission deadline 31 Jan 2026 | Viewed by 120 | Submission Open

Keywords: cardiovascular disease; pathophysiology; therapeutic strategies; translational research; complementary medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Nanotechnology in Pharmaceuticals

edited by Pratap Basim,

Geetha Vaskuri

and

Nagavendra Kommineni

submission deadline 31 Jan 2026 | Viewed by 110 | Submission Open

Keywords: nanotechnology; drug delivery; diagnostics; theranostics; biomimetics; nanocarriers; targeted delivery; routes of administration

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Organisms as Diagnostic Technologies: Harnessing Life for Sensing Mechanisms

edited by

Takaaki Hirotsu

and Hideshi Ishii

submission deadline 31 Jan 2026 | Viewed by 95 | Submission Open

Keywords: biological sensors; diagnostic technologies; diagnostic technologies; biological sensing mechanisms; conversion of biological signals; bio-interfaces

(This special issue belongs to the Section Biomedical Engineering and Materials)

Additive Manufacturing in Biomedical Applications

edited by

Paweł Turek

submission deadline 31 Jan 2026 | Viewed by 78 | Submission Open

Keywords: additive manufacturing; scaffolds; implant; anatomical models; in vivo; in vitro; surface texture; geometrical accuracy; biomaterials; surface roughness

(This special issue belongs to the Section Biomedical Engineering and Materials)

Atrial Fibrillation: From Pathogenesis to Treatment Strategies

edited by

Dimitrios A. Vrachatis

, Theodore G. Papaioannou and

Ioannis Anagnostopoulos

submission deadline 31 Jan 2026 | Viewed by 78 | Submission Open

Keywords: atrial fibrillation; arrhythmia; ablation; PFA; radiofrequency; cryoablation; pathophysiology; pathophysiology; molecular mechanisms

(This special issue belongs to the Section Molecular and Translational Medicine)

Metabolic Disorders and Their Complications: From Molecular Mechanisms to Therapeutic Perspectives

edited by

Sandeep Kumar

Abhishek Gupta

and

Atul Kumar Pandey

submission deadline 31 Jan 2026 | Viewed by 63 | Submission Open

Keywords: metabolism; diabetes; obesity; nutrition; AMPK and mTOR

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Exosomes in Medicine: Recent Advances in Drug Delivery, Diagnostics, and Therapeutics

edited by Vetriselvan Subramaniyan

submission deadline 31 Jan 2026 | Viewed by 60 | Submission Open

Keywords: exosomes; drug delivery; diagnostics; therapeutics; precision medicine; biomarkers; nanomedicine; inflammation and neurodegeneration; exosome engineering; translational research

(This special issue belongs to the Section Gene and Cell Therapy)

Pathogenesis, Diagnostics and Therapeutics in Obsterics and Gynaecology (2nd Edition)

edited by

Nikolaos Machairiotis

submission deadline 31 Jan 2026 | Viewed by 59 | Submission Open

Keywords: gynaecology; obstetrics; diagnosis; pathogenesis; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Antibody Responses to Viral Infections: Insights from Structural Biology

edited by Pragati Agnihotri and

Sharanbasappa Karade

submission deadline 31 Jan 2026 | Viewed by 52 | Submission Open

Keywords: crystal structure; virus– antibody complexes; broadly neutralizing antibodies; immunology; epitope mapping

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Molecular Mechanisms and Translational Research on Insulin Resistance

edited by

Terisha Ghazi

submission deadline 31 Jan 2026 | Viewed by 52 | Submission Open

Keywords: insulin resistance; type 2 diabetes mellitus; metabolic syndrome; insulin signaling; inflammation; oxidative stress; mitochondrial dysfunction; epigenetics; epitranscriptomics (e.g.; m6A RNA methylation); biomarkers; translational medicine; therapeutic targets

(This special issue belongs to the Section Endocrinology and Metabolism Research)

New Advances in Biomaterials for Tissue Repair and Regeneration

edited by Fei Xing, Wen Nie and Zhao Chen

submission deadline 31 Jan 2026 | Viewed by 51 | Submission Open

Keywords: biomaterials; nanomaterials; tissue repair; 3D printing; functionals biomaterials; biomaterial science; tissue regeneration

(This special issue belongs to the Section Biomedical Engineering and Materials)

Urothelial Carcinoma: Role of Biomarkers in Diagnosis, Prognosis and Treatment (2nd Edition)

edited by Ioannis Zachos and

Panagiotis Vlachostergios

submission deadline 31 Jan 2026 | Viewed by 51 | Submission Open

Keywords: urothelial carcinoma; biomarker; diagnosis; treatment; prognosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Pharmacogenetics and Pharmacogenomics: Driving Forces in Modern Precision Medicine

edited by Miriam Saiz-Rodríguez and Dora Koller

submission deadline 31 Jan 2026 | Viewed by 48 | Submission Open

Keywords: pharmacogenetics; pharmacogenomics; precision medicine; polygenic risk scores; phenoconversion; drug response; genetic biomarkers; personalized therapy; underrepresented populations; clinical implementation

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Molecular Signatures and Therapeutic Strategies in Urological Cancers

edited by Haoyue Sheng

submission deadline 31 Jan 2026 | Viewed by 47 | Submission Open

Keywords: urological cancers; molecular signatures; precision medicine; non-coding RNAs; tumor microenvironment

(This special issue belongs to the Section Molecular and Translational Medicine)

Biologics for Bone and Soft Tissue Regeneration: What Is New, What Is True—Second Edition

edited by

Ashim Gupta

Nicola Maffulli

and

Erwin Pavel Lamparelli

submission deadline 31 Jan 2026 | Viewed by 45 | Submission Open

Keywords: regenerative medicine; stem cells; exosomes; musculoskeletal injuries; osteoarthritis; tissue regeneration; tissue engineering; biologics; bone; soft tissue

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advances in 3D Printing for Drug Delivery Systems

edited by

Ion-Bogdan Dumitrescu

, Cristina Manuela Drăgoi and Alina Crenguța Nicolae

submission deadline 31 Jan 2026 | Viewed by 44 | Submission Open

Keywords: 3D printing; drug delivery systems; personalized medicine; pharmaceutical engineering; controlled release

(This special issue belongs to the Section Biomedical Engineering and Materials)

Cell Cycle in Normal Physiology and Disease

edited by

Chen Chu

submission deadline 31 Jan 2026 | Viewed by 43 | Submission Open

Keywords: cell cycle; DNA replication; DNA damage; cyclins; cyclin-dependent kinases (CDKs); CDK inhibitors; cell proliferation; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

Glaucoma: New Diagnostic and Therapeutic Approaches, 3rd Edition

edited by

Da-Wen Lu

submission deadline 31 Jan 2026 | Viewed by 43 | Submission Open

Keywords: glaucoma; ocular pharmacology; ocular disease

(This special issue belongs to the Section Molecular and Translational Medicine)

Gut Microbiota, Diet, and Immunity: Investigating the Connections and Implications for Disease Development—3rd Edition

edited by

Farhad Vahid

submission deadline 31 Jan 2026 | Viewed by 42 | Submission Open

Keywords: gut microbiota; diet; immunity; microbiome; dysbiosis; inflammatory bowel diseases; cancer; CVD; T2D; obesity; overweight; autoimmune diseases; metabolic syndromes; immunomodulation; microbial diversity; nutrient– gut microbiota interactions; probiotics; prebiotics; immune system development; disease susceptibility; therapeutic interventions; host– microbe interactions; gut– brain axis; microbial metabolites; precision nutrition

(This special issue belongs to the Section Molecular and Translational Medicine)

Autonomic Disorders: From Mechanisms to Therapeutic Approaches

edited by Svetlana Blitshteyn

submission deadline 31 Jan 2026 | Viewed by 42 | Submission Open

Keywords: autonomic disorders; autonomic dysfunction; dysautonomia; orthostatic intolerance; therapeutics

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms and Novel Therapeutic Approaches for Nephrology

edited by

Fang-Fang He

submission deadline 31 Jan 2026 | Viewed by 42 | Submission Open

Keywords: chronic kidney disease; acute kidney injury; therapeutics; molecular mechanisms; biomarkers; drug discovery; regenerative medicine; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Risk Factors and Molecular Mechanisms in Diabetes and Cardiovascular Complications

edited by

Xiao Liu

submission deadline 31 Jan 2026 | Viewed by 39 | Submission Open

Keywords: diabetes; cardiovascular disease; atherosclerosis; ischemic heart disease; insulin resistance; risk factors; molecular mechanisms

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advancements in Research on Pancreatic Cancer: From Biomarkers to Targeted Therapies

edited by

Konstantinos Dimas

submission deadline 31 Jan 2026 | Viewed by 39 | Submission Open

Keywords: pancreatic cancer; novel biomarkers; diagnostic techniques; therapeutic approaches

(This special issue belongs to the Section Cancer Biology and Oncology)

Biologic Drugs: The Evolution of Asthma Therapeutics

edited by

Girolamo Pelaia

and

Corrado Pelaia

submission deadline 31 Jan 2026 | Viewed by 38 | Submission Open

Keywords: severe asthma; IgE; IL-4; IL-5; IL-13; TSLP; monoclonal antibodies

(This special issue belongs to the Section Immunology and Immunotherapy)

Tumour Angiogenesis and Anti-Angiogenic Therapy

edited by

Krishna Priya Syama

submission deadline 31 Jan 2026 | Viewed by 37 | Submission Open

Keywords: tumour angiogenesis; vascularization; endothelial cells; pericytes; vascular endothelial growth factor (VEGF); bevacizumab; micro vessel density; anti-angiogenic therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Exploring Antiangiogenic Agents in Drug Discovery: Molecular Mechanisms and Therapeutic Implications

edited by

Roslida Abdul Hamid

submission deadline 31 Jan 2026 | Viewed by 37 | Submission Open

Keywords: angiogenesis; antiangiogenic agents; signaling pathway; preclinical model; drug discovery; computational tools

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

The Pleiotropic Effects of Statins: Anti-Inflammatory, Anti-Coagulant, and Anti-Proliferative Properties

edited by

Maria Grau

submission deadline 31 Jan 2026 | Viewed by 37 | Submission Open

Keywords: hydroxymethylglutaryl-CoA reductase inhibitors; pharmacoepidemiology; anti-inflammatory properties; anti-coagulant properties; anti-proliferative properties

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Signal Peptides in Health and Disease: Molecular Mechanisms and Therapeutic Potential

edited by

Renata Perlikowska

submission deadline 31 Jan 2026 | Viewed by 36 | Submission Open

Keywords: signal peptides; protein targeting; protein trafficking; therapeutic peptides; synthetic signal peptides; signal recognition particle; drug delivery system; biomarker discovery

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Technologies in the Diagnosis and Management of Neurological Disorders

edited by

Luca Filippi

submission deadline 31 Jan 2026 | Viewed by 36 | Submission Open

Keywords: neurological disorders; advanced diagnostic imaging modalities; neurophysiological tools

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Pharmacological Mechanisms and Target Discovery in Lung Injury-Driven Fibrosis: From Molecular Pathways to Preclinical Innovation

edited by

Huifang Tang

submission deadline 31 Jan 2026 | Viewed by 35 | Submission Open

Keywords: lung injury and fibrosis; pharmacological mechanisms; target discovery; mechanistic drivers; target identification; drug design; preclinical models

(This special issue belongs to the Section Molecular and Translational Medicine)

New Treatments for Colorectal Cancer

edited by

Dhiraj Kumar Sah

submission deadline 31 Jan 2026 | Viewed by 35 | Submission Open

Keywords: biomarkers; signaling pathway; chemotherapy; reactive oxygen species; angiogenesis

(This special issue belongs to the Section Cancer Biology and Oncology)

Extracellular Vesicles and Exosomes as Therapeutic Agents—2nd Edition

edited by

David J. Rademacher

submission deadline 31 Jan 2026 | Viewed by 35 | Submission Open

Keywords: extracellular vesicles; exosomes; therapeutics; drug delivery; bioengineering

(This special issue belongs to the Section Cell Biology and Pathology)

Advanced Research in Liver Diseases

edited by

Marta Melis

submission deadline 31 Jan 2026 | Viewed by 35 | Submission Open

Keywords: liver; obesity; alcohol; oxidative stress; nutrients; vitamins; metabolism; homeostasis

(This special issue belongs to the Section Cell Biology and Pathology)

Biomarkers in Metabolic Disorders, Obesity and Type 2 Diabetes Mellitus—2nd Edition

edited by

Maciej Walędziak

and Anna Maria Różańska-Walędziak

submission deadline 31 Jan 2026 | Viewed by 34 | Submission Open

Keywords: metabolic disorders; obesity; type 2 diabetes mellitus; bariatric surgery; laboratory parameters

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Cell Metabolism in Brain Physiology and Pathology: From Molecular Mechanisms to Therapeutic Targets

edited by

Marco Segatto

and Mayra Colardo

submission deadline 31 Jan 2026 | Viewed by 34 | Submission Open

Keywords: autophagy; energy homeostasis; glucose metabolism; lipids; metabolism; nervous system; oxidative stress; protein metabolism; neurodegeneration; neurodevelopment

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Allergies and Autoimmunity

edited by

Mukesh Verma

submission deadline 31 Jan 2026 | Viewed by 32 | Submission Open

Keywords: asthma; arthritis; diabetes; inflammatory bowel disease; dermatomyositis; Sjö gren's syndrome; systemic lupus erythematosus; psoriasis; multiple sclerosis

(This special issue belongs to the Section Cell Biology and Pathology)

New Advances in Neuroprotective Agent

edited by

Mariano Catanesi

submission deadline 31 Jan 2026 | Viewed by 30 | Submission Open

Keywords: mitochondrial disfunction; antioxidant molecules; gene therapy; stem cell; nanomedicine; cellular reprogramming

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Tumor Microenvironment in Head and Neck Squamous Cell Carcinoma

edited by Julia Federspiel,

Teresa Steinbichler

and

Jozsef Dudas

submission deadline 31 Jan 2026 | Viewed by 30 | Submission Open

Keywords: head and neck oncology 3D tumor models; cancer-associated fibroblasts; phototherapy; exosomes

(This special issue belongs to the Section Cancer Biology and Oncology)

Molecular Pathways and Their Clinical Implications in Ischemic Heart Disease and Heart Failure: From Pathophysiology to Therapeutic Strategies

edited by

Panagiotis Stachteas

and Efstratios Karagiannidis

submission deadline 31 Jan 2026 | Viewed by 30 | Submission Open

Keywords: ischemic heart disease; heart failure; molecular mechanisms; biomarkers; targeted therapy; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Bioactive Lipids in Disease: Diagnosis, Prognosis, and Pathophysiology

edited by

Xu Zhang

submission deadline 31 Jan 2026 | Viewed by 28 | Submission Open

Keywords: bioactive lipids; eicosanoids; endocannabinoids; lysophospholipids; sphingolipids; oxysterols; bile acids; lipidomics; pathophysiology; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Cancer Pharmacology

edited by Zhi Shi

submission deadline 31 Jan 2026 | Viewed by 27 | Submission Open

Keywords: cancer pharmacology; anticancer drug; cancer chemotherapy; targeted therapy; cancer immunotherapy; combination therapy; drug resistance

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

The Latest Advancements in Tumor Drug Delivery Systems

edited by

Mingji Jin

submission deadline 31 Jan 2026 | Viewed by 27 | Submission Open

Keywords: tumor targeting; gene delivery; biomemetic drug delivery; cancer-targeting nanorobot; specific cancer cell targeting; antitumor immunotherapy; cancer nanovaccine; tumor-suppressing nanoenzyme

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Shock Syndromes: Pathophysiology, Diagnostics and Emerging Therapeutics Across the Clinical Spectrum

edited by

George E. Zakynthinos

and

Evangelos Oikonomou

submission deadline 31 Jan 2026 | Viewed by 27 | Submission Open

Keywords: shock; critical illness; cardiogenic shock; septic shock; hypovolemic shock; obstructive shock; inflammation; hemodynamics; artificial intelligence in medicine; precision medicine; vasopressors; mechanical circulatory support; diagnostics

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Therapeutic Approaches to Head and Neck Cancer

edited by

Laura D. Locati

and Daria Maria Filippini

submission deadline 31 Jan 2026 | Viewed by 22 | Submission Open

Keywords: head and neck cancer; HPV-related head and neck cancer; EBV-related nasopharyngeal cancer; prognostic biomarkers; predictive biomarkers; novel combinations; tumor microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

The Prefrontal Cortex in Cognition and Diseases

edited by

Xuehan Zhang

submission deadline 31 Jan 2026 | Viewed by 20 | Submission Open

Keywords: executive function; working memory; behavioral inhibition; attention; anxiety; social behavior; ADHD (attention-deficit hyperactivity disorder); schizophrenia; MDD (major depressive disorder); AD (Alzheimer's disease); PD (Parkinson’ s disease)

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Genetically Determined Cardiovascular Disease

edited by

Gaetano Thiene

submission deadline 31 Jan 2026 | Viewed by 20 | Submission Open

Keywords: genetically determined cardiovascular diseases; genetic mutations; oligogenic inheritance; congenital heart defects; atherosclerosis

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Nanoparticles in Medicine: The Potential of “Empty” Nanoparticles and Future Challenges

edited by Cuthbert O Simpkins and

Zahra Niroobakhsh

submission deadline 31 Jan 2026 | Viewed by 18 | Submission Open

Keywords: nanoparticles; empty nanoparticles; nanoparticle technology

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Advances in Cancer Metastasis Modeling: From Mechanisms to Therapies

edited by

Yi-Hui Wu

submission deadline 31 Jan 2026 | Viewed by 14 | Submission Open

Keywords: cancer metastasis; tumor microenvironment; extracellular matrix; metastasis models; drug resistance; in vivo imaging; molecular mechanisms; targeted therapy; computational modeling; and antibody-drug conjugates

(This special issue belongs to the Section Cancer Biology and Oncology)

Displaying special issue 601-650 on page 13 of 15.

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