Advances of Microbiome in Human Cancers
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 23
Special Issue Editor
Interests: cancer research; cancer diagnostics; head and neck cancer; microbiome; bioinformatics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The human microbiome—comprising trillions of bacteria, viruses, fungi, and other microbes residing in and on the body—has emerged as a key player in cancer biology. Once overlooked, it is now recognized for its influence on cancer initiation, progression, and response to therapy through mechanisms involving inflammation, immune modulation, DNA damage, and microbe-host metabolic interaction. Dysbiosis in the gut or tumor-resident microbiotas has been implicated in cancers of the colon, liver, pancreas, and beyond. As the field rapidly evolves, recent challenges related to data reproducibility and methodological consistency have underscored the need for rigorous standards and validation. This Special Issue aims to highlight recent advances in microbiome research related to human cancers, encompassing mechanistic insights and translational applications. We invite studies exploring microbial biomarkers, interactions with cancer therapies, microbiota-targeting interventions, and translational feasibility. Emphasis will also be placed on interdisciplinary approaches, standardization efforts, tumor-resident microbes, and linkage of microbiotas to clinical outcome, with the goal of advancing the microbiome’s clinical utility in oncology.
Dr. Weg M. Ongkeko
Guest Editor
Manuscript Submission Information
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Keywords
- human microbiome
- gut microbiota
- tumor-resident microbes
- translational research
- biomarkers
- computational biology
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