Precision Oncology in Solid Tumors: Emerging Biomarkers and Therapeutic Targets
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 42
Special Issue Editor
Interests: precision oncology; breast cancer; urogenital cancers; molecular pathology; digital pathology; tumor microenvironment
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The landscape of solid tumor diagnosis and treatment is undergoing a profound transformation driven by advances in molecular profiling, biomarker discovery, and targeted therapeutics. Precision oncology has evolved from a conceptual framework to a clinical reality, enabling the stratification of patients based on genetic, epigenetic, and immune features. This Special Issue aims to highlight recent breakthroughs and remaining challenges in the identification and clinical implementation of predictive and prognostic biomarkers across major solid tumors.
Topics will include the integration of next-generation sequencing, liquid biopsy, and spatial multi-omics for comprehensive tumor characterization; the development of novel therapeutic targets and immune regulation; and the role of artificial intelligence and digital pathology in refining diagnostic precision. Attention will also be given to mechanisms of therapeutic resistance, tumor microenvironment modulation, and innovative combination strategies involving immunotherapy, antibody–drug conjugates, and epigenetic drugs.
By bringing together contributions from pathologists, oncologists, and translational scientists, this Special Issue seeks to provide a multidisciplinary overview of how molecular insights are reshaping cancer care. Ultimately, the goal is to bridge the gap between laboratory discoveries and clinical application, fostering a more individualized, data-driven approach to cancer diagnosis and treatment.
Dr. Giuseppe Nicolò Fanelli
Guest Editor
Manuscript Submission Information
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Keywords
- precision oncology
- predictive biomarkers
- target therapy
- molecular pathology
- liquid biopsy
- tumor microenvironment
- immunotherapy
- multi-omics integration
- artificial intelligence
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