Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Hepatotoxicity: From Pathology to Novel Therapeutic Approaches (2nd Edition)
edited by
submission deadline 15 Aug 2026 | 2 articles | Viewed by 7573 | Submission Open
Keywords: cell death; reactive metabolites; oxidative stress; stress signaling; mitochondria; adaptive immunity; HLA associations; hepatotoxicity; drugs; liver injury; adverse drug reaction; drug-induced autoimmune hepatitis; idiosyncratic-drug-induced liver injury; bile acid; drug-induced cholestasis; hepatotoxins; steatosis; fibrosis
(This special issue belongs to the Section Molecular and Translational Medicine)
Gut Microbiota, Diet, and Immunity: Investigating the Connections and Implications for Disease Development—3rd Edition
edited by
submission deadline 30 Aug 2026 | 4 articles | Viewed by 14475 | Submission Open
Keywords: gut microbiota; diet; immunity; microbiome; dysbiosis; inflammatory bowel diseases; cancer; CVD; T2D; obesity; overweight; autoimmune diseases; metabolic syndromes; immunomodulation; microbial diversity; nutrient–gut microbiota interactions; probiotics; prebiotics; immune system development; disease susceptibility; therapeutic interventions; host–microbe interactions; gut–brain axis; microbial metabolites; precision nutrition
(This special issue belongs to the Section Molecular and Translational Medicine)
Placental, Vascular, and Immune Molecular Pathways in Pregnancy Complications submission deadline 30 Aug 2026 | 1 articles | Viewed by 845 | Submission Open
Keywords: pregnancy-related complications; pathophysiological mechanisms; perinatal outcomes; perinatal diagnosis; placental dysfunction; maternal–fetal interface; fetal growth; translational medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Allergies and Autoimmunity
edited by
submission deadline 30 Aug 2026 | Viewed by 331 | Submission Open
Keywords: asthma; arthritis; diabetes; inflammatory bowel disease; dermatomyositis; Sjögren's syndrome; systemic lupus erythematosus; psoriasis; multiple sclerosis
(This special issue belongs to the Section Cell Biology and Pathology)
Molecular Mechanisms and Novel Therapies for Brain Injury: 3rd Edition
edited by
submission deadline 30 Aug 2026 | Viewed by 282 | Submission Open
Keywords: stroke; spinal cord injury; traumatic brain injury; seizure; brain tumors; neurodegeneration; neuroinflammation; blood–brain barrier disruption; neuroprotection; drug discover; mechanism of action; target validation
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Antimicrobial Resistance in Constrained Settings: Advances and Challenges to Fight the “Silent Pandemic”
edited by Elisa Gentilotti
submission deadline 30 Aug 2026 | Viewed by 237 | Submission Open
Keywords: antimicrobial stewardship; infection prevention and control; low- and middle-income countries; antimicrobial resistance; antimicrobials; surveillance
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Multiple Sclerosis: Diagnosis and Treatment—3rd Edition
edited by
submission deadline 31 Aug 2026 | 5 articles | Viewed by 23929 | Submission Open
Keywords: multiple sclerosis; pathogenesis; progressive MS; MRI; disease-modifying therapies; demyelinating disorders; cognitive dysfunction; intestinal microbiota
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advanced Research on Psychiatric Disorders
edited by Wen Zhang
submission deadline 31 Aug 2026 | 8 articles | Viewed by 20451 | Submission Open
Keywords: psychiatric disorders; artificial intelligence; predictive modeling; personalized treatment strategies; animal experiments; risk factors; multimodal approaches
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis and Novel Therapeutics in Musculoskeletal Conditions, 3rd Edition submission deadline 31 Aug 2026 | 6 articles | Viewed by 20298 | Submission Open
Keywords: neck pain; low back pain; myofascial pain syndromes; chronic pain; musculoskeletal disorders; disability; pain treatment
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research in Breast Diseases and Histopathology
edited by Michał Budzik
submission deadline 31 Aug 2026 | 6 articles | Viewed by 18123 | Submission Open
Keywords: breast cancer; breast diseases; histopathology; biomarkers; screening; diagnosis; early detection; tumor microenvironment; pathophysiology; molecular biology
(This special issue belongs to the Section Cell Biology and Pathology)
Molecular Research in Breast Cancer submission deadline 31 Aug 2026 | 7 articles | Viewed by 17872 | Submission Open
Keywords: breast cancer; apoptosis; signaling pathways; drug resistance; metastasis; cancer stem cells; microRNA; biomarkers; drug target; tumor metabolism; tumor immunity
(This special issue belongs to the Section Molecular and Translational Medicine)
Periodontal Disease and Periodontal Tissue Regeneration—Second Edition submission deadline 31 Aug 2026 | 9 articles | Viewed by 13810 | Submission Open
Keywords: periodontal diagnosis; periodontal immunology; periodontal microbiology; periodontal tissue regeneration; tissue engineering
(This special issue belongs to the Section Biomedical Engineering and Materials)
Animal Models for the Study of Cardiovascular Physiology—Second Edition
edited by Sandra Lia Amaral
submission deadline 31 Aug 2026 | 9 articles | Viewed by 13780 | Submission Open
Keywords: hypertension; stroke; myocardium infarction; arterial stiffness; supravalvular aortic stenosis; cardiac remodeling; capillary angiogenesis; exercise training; vascular diseases; non-pharmacological treatment
(This special issue belongs to the Section Cell Biology and Pathology)
Pathogenesis, Diagnostics and Therapeutics in Obsterics and Gynaecology (2nd Edition) submission deadline 31 Aug 2026 | 10 articles | Viewed by 13420 | Submission Open
Keywords: gynaecology; obstetrics; diagnosis; pathogenesis; treatment
(This special issue belongs to the Section Molecular and Translational Medicine)
New Advances in Pulmonary Fibrosis
edited by
submission deadline 31 Aug 2026 | 3 articles | Viewed by 12701 | Submission Open
Keywords: pulmonary fibrosis; interstitial lung disease; antifibrotic therapy; precision medicine; imaging diagnostics; novel therapeutics; pathobiology; artificial intelligence
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements in Cardiac Imaging: Diagnostics, Prognostics, and Therapeutics
edited by Ilaria Dentamaro
submission deadline 31 Aug 2026 | 8 articles | Viewed by 11265 | Submission Open
Keywords: cardiac imaging; echocardiography; cardiovascular magnetic resonance imaging; cardio CT; nuclear cardiology
(This special issue belongs to the Section Molecular and Translational Medicine)
Mechanisms and Novel Therapeutic Approaches for Nephrology
edited by
submission deadline 31 Aug 2026 | 2 articles | Viewed by 9314 | Submission Open
Keywords: chronic kidney disease; acute kidney injury; therapeutics; molecular mechanisms; biomarkers; drug discovery; regenerative medicine; precision medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Genetic Research and Molecular Diagnostics for Hematological Diseases
edited by Ying S. Zou and Leonard N. Yenwongfai
submission deadline 31 Aug 2026 | 6 articles | Viewed by 9303 | Submission Open
Keywords: hematological diseases; genetic research; benign hematology; inherited disorders; next-generation sequencing/long-read sequencing; optical genome mapping; transcriptome; proteomics; digital pathology; deep convolutional neural networks
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Advances in Combination Therapy for Chronic Diseases: Bridging Conventional and Natural Products for Enhanced Outcomes
edited by
submission deadline 31 Aug 2026 | 4 articles | Viewed by 8067 | Submission Open
Keywords: combination therapy; interaction; chronic diseases; synergy; molecular pathways; mathematical methods; minimizing side effects
(This special issue belongs to the Section Molecular and Translational Medicine)
Glaucoma: New Diagnostic and Therapeutic Approaches, 3rd Edition
edited by
submission deadline 31 Aug 2026 | 7 articles | Viewed by 7353 | Submission Open
Keywords: glaucoma; ocular pharmacology; ocular disease
(This special issue belongs to the Section Molecular and Translational Medicine)
Inflammatory Bowel Diseases: New Diagnostic and Therapeutic Approaches—Second Edition submission deadline 31 Aug 2026 | 2 articles | Viewed by 6459 | Submission Open
Keywords: bowel inflammation; Crohn’s disease; endoscopy; inflammatory bowel disease; targeted therapy; ulcerative colitis
(This special issue belongs to the Section Immunology and Immunotherapy)
Epigenetics in Human Cancer: Emerging Biomarkers and Therapeutic Targets
edited by
submission deadline 31 Aug 2026 | 3 articles | Viewed by 5744 | Submission Open
Keywords: cancer; epigenetics; DNA methylation; histone modification; chromatin remodeling; non-coding RNAs; therapeutic resistance
(This special issue belongs to the Section Cancer Biology and Oncology)
Cardiovascular and Metabolic Disease: New Treatment and Future Directions—5th Edition
edited by
submission deadline 31 Aug 2026 | 6 articles | Viewed by 5509 | Submission Open
Keywords: cardiovascular disease; metabolic disease; diabetes; therapy; drugs; implantable device; heart failure; heart transplantation; cardiac surgery; future directions
(This special issue belongs to the Section Molecular and Translational Medicine)
Glomerular Disease and Cystic Kidney Disease: From Pathogenesis to Novel Therapeutic Approaches—2nd Edition
edited by Vassilis Filiopoulos and
submission deadline 31 Aug 2026 | 1 articles | Viewed by 5262 | Submission Open
Keywords: glomerular disease; glomerulonephritis; glomerulopathy; podocytopathies; ciliopathies; cystic kidney disease; polycystic kidney disease; tolvaptan; vasopressin
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Research and Recent Advances in Diabetic Retinopathy—3rd Edition submission deadline 31 Aug 2026 | 3 articles | Viewed by 5190 | Submission Open
Keywords: diabetes; diabetic retinopathy; complications; vascular endothelial growth factor; retina; biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
Mechanism of Mesenchymal Stromal Cells and Their Derivatives in Regenerative Medicine
edited by and
submission deadline 31 Aug 2026 | 3 articles | Viewed by 4455 | Submission Open
Keywords: mesenchymal stromal cell; regenerative medicine; stem cell; extracellular vesicle; mechanism of action; paracrine factor; secretome; tissue engineering
(This special issue belongs to the Section Biomedical Engineering and Materials)
Drug Discovery of Novel Anti-Inflammatory Compounds, Their Molecular Targets, and Translational Advancements
edited by Shomaila Mehmood
submission deadline 31 Aug 2026 | 1 articles | Viewed by 3972 | Submission Open
Keywords: natural products; drug discovery; anti-inflammatory; oxidative stress; nitrative stress; immunomodulation; molecular mechanisms; signaling pathways; inflammatory diseases; bioavailability; translational research
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Neurodevelopmental and Neuropsychiatric Disorders in Animal Models
edited by Yael Abreu-Villaça
submission deadline 31 Aug 2026 | 2 articles | Viewed by 3717 | Submission Open
Keywords: mood disorder; mental disorder; substance use disorder; autism spectrum disorder (ASD); attention-deficit/hyperactive disorder (ADHD); depression and anxiety disorders; schizophrenia; bipolar disorder; epilepsy; eating disorders
(This special issue belongs to the Section Molecular and Translational Medicine)
Tumor Microenvironment in Cancer: Basic Science, Artificial Intelligence, and Clinical Research
edited by Rada Amin
submission deadline 31 Aug 2026 | 3 articles | Viewed by 3638 | Submission Open
Keywords: tumor microenvironment; cancer progression; malignancies; immunotherapy; therapy resistance; immune evasion
(This special issue belongs to the Section Cancer Biology and Oncology)
Roles of Extracellular Vesicles in the Complex Interaction Between Metabolic Disorder and Cancer
edited by
submission deadline 31 Aug 2026 | 3 articles | Viewed by 3388 | Submission Open
Keywords: extracellular vesicles; metabolic disorders; obesity; diabetes; cardiovascular diseases; cancer; mechanism; diagnosis; treatment
(This special issue belongs to the Section Molecular and Translational Medicine)
Omics Approaches on Immune-Mediated Inflammatory Diseases: Towards Novel Biomarkers and Potential Therapeutic Targets, 3rd Edition submission deadline 31 Aug 2026 | 1 articles | Viewed by 3316 | Submission Open
Keywords: IMIDs; IBD; Crohn’s disease; ulcerative colitis; SLE; Sjogren’s syndrome; rheumatoid arthritis; psoriatic arthritis; multiple sclerosis; bulk and single-cell omics; multi-omics flow cytometry; next-generation microscopy; tissue microarrays; systems biology
(This special issue belongs to the Section Immunology and Immunotherapy)
Drug Resistance and Novel Targets for Cancer Therapy—Third Edition submission deadline 31 Aug 2026 | 3 articles | Viewed by 3226 | Submission Open
Keywords: cancer; drug resistance; targeted therapy; conventional chemotherapy; natural products; molecular targets; cancer hallmarks; therapeutic agents
(This special issue belongs to the Section Cancer Biology and Oncology)
MicroRNAs in Precision Medicine: Regulation, Biomarkers and Novel Therapeutics
edited by Shing Cheng Tan
submission deadline 31 Aug 2026 | 2 articles | Viewed by 3116 | Submission Open
Keywords: MicroRNAs; non-coding RNAs; biomarkers; therapeutic targets; cancer; omics technologies; precision medicine; disease pathogenesis
(This special issue belongs to the Section Molecular and Translational Medicine)
Translational and Precision Medicine in Osteoarthritis, Bone Healing and Musculoskeletal Diseases
edited by , and Heather Elizabeth Owston
submission deadline 31 Aug 2026 | 3 articles | Viewed by 2825 | Submission Open
Keywords: osteoarthritis; non-union; osteoporosis; fracture related infection; fragility; bone regeneration; mesenchymal stromal cells; tissue engineering; scaffolds; growth factors
(This special issue belongs to the Section Molecular and Translational Medicine)
Cell Metabolism in Brain Physiology and Pathology: From Molecular Mechanisms to Therapeutic Targets
edited by and Mayra Colardo
submission deadline 31 Aug 2026 | 2 articles | Viewed by 2620 | Submission Open
Keywords: autophagy; energy homeostasis; glucose metabolism; lipids; metabolism; nervous system; oxidative stress; protein metabolism; neurodegeneration; neurodevelopment
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Biologics for Bone and Soft Tissue Regeneration: What Is New, What Is True—Second Edition submission deadline 31 Aug 2026 | 1 articles | Viewed by 2537 | Submission Open
Keywords: regenerative medicine; stem cells; exosomes; musculoskeletal injuries; osteoarthritis; tissue regeneration; tissue engineering; biologics; bone; soft tissue
(This special issue belongs to the Section Biomedical Engineering and Materials)
Metabolic Disorders and Their Complications: From Molecular Mechanisms to Therapeutic Perspectives submission deadline 31 Aug 2026 | 1 articles | Viewed by 2222 | Submission Open
Keywords: metabolism; diabetes; obesity; nutrition; AMPK and mTOR
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Nanotechnology in Pharmaceuticals
edited by Pratap Basim, and
submission deadline 31 Aug 2026 | 2 articles | Viewed by 2079 | Submission Open
Keywords: nanotechnology; drug delivery; diagnostics; theranostics; biomimetics; nanocarriers; targeted delivery; routes of administration
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Exploring Neuroinflammation in Central and Peripheral Neuropathic Pain and Related Disorders
edited by
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1948 | Submission Open
Keywords: neuroinflammation; neuropathic pain; central nervous system; peripheral nervous system; affective disorders; cognitive disorders; in silico modeling; in vitro assays; in vivo models; medical and non-pharmacological interventions
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advances in Hematological Malignancies: Diagnostic Strategies, Molecular Mechanisms, Prognostic Markers and Therapeutic Approaches
edited by José Antonio García-Vela and Fernando Martin-Moro
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1898 | Submission Open
Keywords: hematological malignancies; diagnostic strategies; hematopathology; flow cytometry; molecular biology; prognostic markers; targeted therapies; immunotherapy; cellular therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Hepatic and Gastrointestinal Diseases in Germany (2nd Edition)
edited by
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1771 | Submission Open
Keywords: biomarker; prevalence; Germany; inflammatory bowel disease; cancer
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Pathogenesis and Treatment of Infectious Diseases
edited by Francesca Gioia
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1770 | Submission Open
Keywords: antimicrobial resistance; phage therapy; host–pathogen interactions; molecular diagnostics; immunotherapy
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Biologic Drugs: The Evolution of Asthma Therapeutics submission deadline 31 Aug 2026 | 2 articles | Viewed by 1741 | Submission Open
Keywords: severe asthma; IgE; IL-4; IL-5; IL-13; TSLP; monoclonal antibodies
(This special issue belongs to the Section Immunology and Immunotherapy)
Recent Advances in Sickle Cell Disease
edited by
submission deadline 31 Aug 2026 | 2 articles | Viewed by 1673 | Submission Open
Keywords: sickle cell disease; education; screening; chronic pain; pain mechanisms; disease-modifying therapies; cell-based gene therapies; pain management; comprehensive disease management
(This special issue belongs to the Section Molecular and Translational Medicine)
Risk Factors and Molecular Mechanisms in Diabetes and Cardiovascular Complications
edited by
submission deadline 31 Aug 2026 | 2 articles | Viewed by 1646 | Submission Open
Keywords: diabetes; cardiovascular disease; atherosclerosis; ischemic heart disease; insulin resistance; risk factors; molecular mechanisms
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Technological Innovations Transforming Cerebrovascular Disease Management
edited by Lawrence Ka Sing Wong
submission deadline 31 Aug 2026 | 2 articles | Viewed by 1578 | Submission Open
Keywords: cerebrovascular diseases; stroke; new technology; diagnostic imaging; thrombolysis; mechanical thrombectomy; robotic exoskeleton; artificial intelligence; brain–computer interface
(This special issue belongs to the Section Molecular and Translational Medicine)
Insights into Retinal Development, Disease, and Neuroprotection with Pharmacologic and Perioperative Considerations
edited by Siyuan Song
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1389 | Submission Open
Keywords: retinal development; retinal degeneration; diabetic retinopathy; glaucoma/optic neuropathy; neuroprotection; neuroinflammation; microglia; single-cell/spatial omics; retinal organoids; anesthesia and analgesia
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Immune Cell Plasticity in Malignancy and Autoimmunity: Mechanism and Implication
edited by Joanna Kosalka-Wegiel, Aleksandra H. Opinc-Rosiak, and
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1235 | Submission Open
Keywords: immune cell plasticity; autoimmune diseases; systemic autoimmunity; organ-specific autoimmunity; immune dysregulation; pathophysiology; molecular mechanisms; immune biomarkers; immunotherapy; targeted therapies
(This special issue belongs to the Section Cell Biology and Pathology)
Current Challenges and Future Trends in Intracranial Aneurysms: Mechanisms, Biomarkers, and Therapeutic Strategies
edited by Zhongsong Shi and
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1176 | Submission Open
Keywords: intracranial aneurysm; subarachnoid hemorrhage; inflammation; immune; smooth muscle cell; endothelial dysfunction; hemodynamic forces; biomarkers; neuroimaging; non-coding RNA; multi-omics; endovascular treatment; computational fluid dynamic
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Fibroblasts: Insights from Molecular and Pathophysiology Perspectives—2nd Edition
edited by and
submission deadline 31 Aug 2026 | 2 articles | Viewed by 1154 | Submission Open
Keywords: fibroblasts and myofibroblasts; fibrosis (organ and tissue fibrosis); tissue remodelling; extracellular matrix; cellular signalling; fibroblast differentiation; new in vitro models of fibrotic-related diseases
(This special issue belongs to the Section Cell Biology and Pathology)
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