Molecular Research in Breast Cancer
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 1194
Special Issue Editors
Interests: TNBC; miRNA; cell death; cancer stem cells
Special Issues, Collections and Topics in MDPI journals
Interests: cancer; cancer stem cells; oxidative stress; antioxidant activity cell death; cancer therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Breast cancer, one of the most common cancers affecting women worldwide, is classified based on its histological and molecular variability. This variability influences prognosis and treatment strategies, making breast cancer a complex disease to study and manage. One particularly heterogeneous subgroup is triple-negative breast cancer (TNBC), characterized by the absence of PR, ER, and HER2/NEU receptor expression. This molecular profile confers TNBC a particularly metastatic and invasive nature, along with drug resistance and a poor prognosis. Consequently, TNBC lacks specific molecular targets, making it difficult to establish effective therapeutic strategies, and conventional chemotherapy remains the primary treatment option.
The Special Issue, titled “Molecular Research in Breast Cancer”, aims to collect recent findings in this context, such as the following:
- Genetic, epigenetic, and transcriptional profiles;
- Descriptions of proteomic features and biochemical pathways;
- Identification of cancer stem cells and their interactions with the microenvironment;
- Metabolic reprogramming;
- Effects induced by various drugs, in vitro and in vivo;
- Breast cancer immunity and metabolic reprogramming;
- Any evidence useful in identifying novel molecular targets to address the aggressive nature of TNBC.
We welcome contributions that enhance our understanding of breast cancer at the molecular level, providing insights that could lead to more effective treatments and improved patient outcomes.
Dr. Anna De Blasio
Dr. Daniela Carlisi
Guest Editors
Manuscript Submission Information
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Keywords
- breast cancer
- apoptosis
- signaling pathways
- drug resistance
- metastasis
- cancer stem cells
- microRNA
- biomarkers
- drug target
- tumor metabolism
- tumor immunity
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Related Special Issue
- Molecular Research of Triple-Negative Breast Cancer in Biomedicines (9 articles)
