Metabolic Disorders and Their Complications: From Molecular Mechanisms to Therapeutic Perspectives
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Endocrinology and Metabolism Research".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 32
Special Issue Editors
Interests: diabetes; obesity; inflammatory disease; necroptosis; sarcopenia
Special Issues, Collections and Topics in MDPI journals
Interests: metabolic disease; lipid metabolism; type 2 diabetes; obesity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolic disturbances refer to disruptions in the body's normal chemical processes, specifically those involved in converting food into energy and utilizing nutrients, which are responsible for various functions such as breathing, circulation, and growth. These disturbances can cause metabolic disorders, which are mainly associated with nutrients, energy, and other essential molecules. The main causes of these problems are linked to biochemical pathways that regulate metabolism, due to genetic defects, lifestyle factors, or a combination of both. They can impact various organs and systems in the body, leading to a wide range of complications. The prevalence of metabolic disorders is increasing rapidly worldwide. The key signaling pathways that regulate metabolism include insulin signaling, AMP-activated protein kinase (AMPK), mechanistic target of rapamycin (mTOR), and other critical metabolic regulators. Metabolic disease is also influenced by the effects of environmental factors, such as diet and lifestyle, on the expression of genes related to metabolic regulation and disease susceptibility. Therefore, we must take control of these metabolic problems in order to improve human health. The main metabolism-related disorders are as follows:
- Diabetes;
- Obesity and metabolic syndrome;
- Polycystic ovarian syndrome;
- Cardiovascular disease;
- Neurological complications;
- Kidney problems;
- Endocrine dysfunction;
- Cancer risk.
Dr. Sandeep Kumar
Dr. Abhishek Gupta
Dr. Atul Kumar Pandey
Guest Editors
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Keywords
- metabolism
- diabetes
- obesity
- nutrition
- AMPK and mTOR
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