Exploring Neuroinflammation in Central and Peripheral Neuropathic Pain and Related Disorders
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 33
Special Issue Editor
Interests: neuroscience; neuroinflammation; neuropsychological disorders; pathway analysis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neuropathic pain, driven by central and peripheral nervous system dysfunction, is intricately linked to neuroinflammation and often accompanied by affective (e.g., anxiety and depression) and cognitive (e.g., memory deficits and executive dysfunction) disorders. This Special Issue of Biomedicines invites preclinical research and review articles utilizing in silico, in vitro, and in vivo approaches to elucidate neuroinflammatory mechanisms in neuropathic pain and its comorbidities. We welcome studies employing computational modeling (in silico), cell-based assays (in vitro), and animal models (in vivo) to explore molecular pathways, cytokine signaling, and neuroimmune interactions. Submissions should focus on identifying novel biomarkers, therapeutic targets, or signaling cascades, emphasising medical, chemical, and non-pharmacological (e.g., neuromodulation and lifestyle interventions) treatment strategies. Clinical trial data will be excluded. We encourage contributions leveraging advanced techniques, such as omics-based pathway analyses, neural circuit modeling, or neuroimmune modulation, to address the interplay between neuropathic pain and affective–cognitive impairments. This issue aims to advance preclinical neuroscience, fostering innovative therapeutic strategies for debilitating conditions.
Dr. Tahmineh Mokhtari
Guest Editor
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Keywords
- neuroinflammation
- neuropathic pain
- central nervous system
- peripheral nervous system
- affective disorders
- cognitive disorders
- in silico modeling
- in vitro assays
- in vivo models
- medical and non-pharmacological interventions
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