Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Physiology and Pathophysiology of the Kidney
edited by Gang Liu
submission deadline 30 Nov 2026 | 5 articles | Viewed by 11607 | Submission Open
Keywords: renal physiology; renal hemodynamics; kidney injury; regenerative therapies; urology
(This special issue belongs to the Section Physiology)
Regulatory Mechanisms of Plant Stress Response
edited by and Li Ren
submission deadline 30 Nov 2026 | 3 articles | Viewed by 9700 | Submission Open
Keywords: gene; gene expression; gene function; molecular regulation; genetic resource; phenotype; stress response
(This special issue belongs to the Section Genetics and Genomics)
Neurodegeneration: Pathways and Mechanisms submission deadline 30 Nov 2026 | 4 articles | Viewed by 8349 | Submission Open
Keywords: inflammation; oxidative stress; apoptosis; exercise; diet; cellular pathways
(This special issue belongs to the Section Neuroscience)
Ecological Dynamics of Vector-Borne Pathogens: From Hosts to Vectors submission deadline 30 Nov 2026 | 2 articles | Viewed by 5473 | Submission Open
Keywords: vector-borne pathogens; host–vector interactions; climate change; disease emergence
(This special issue belongs to the Section Microbiology)
Impact of Climate Change on Structural and Functional Characteristics of Freshwater Ecosystems and Its Implications for Their Resources’ Management submission deadline 30 Nov 2026 | 1 articles | Viewed by 5453 | Submission Open
Keywords: AI applications; biodiversity; biological assemblages; climate change; ecological resilience; ecosystem ser-vices; freshwater ecosystems; nutrient cycling; temperature
(This special issue belongs to the Section Ecology)
Genetics and Cell Biology in Crop Improvement
edited by , , Jie Huang and Xixi Liu
submission deadline 30 Nov 2026 | 1 articles | Viewed by 4891 | Submission Open
Keywords: plant genomics and genetics; gene cloning and function; crop molecular breeding; germplasm enhancement; genetic engineering; plant cell biology; crop adaptability
(This special issue belongs to the Section Plant Science)
Breast Cancer: Molecular and Cellular Mechanism and Biomarkers submission deadline 30 Nov 2026 | 4 articles | Viewed by 4340 | Submission Open
Keywords: breast cancer; biomarkers; molecular mechanisms; multidrug resistance; personalized medicine; molecular targeted therapy; gene expression
(This special issue belongs to the Section Cancer Biology)
The Role of Lipids in Cardiovascular and Neurodegenerative Diseases
edited by , and Yaxin Li
submission deadline 30 Nov 2026 | 1 articles | Viewed by 3941 | Submission Open
Keywords: lipid biology; lipid peroxidation; lipidomics; lipid foods or nutrients; cardiovascular disease; neurodegenerative diseases
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Insect Habits, Habitats and Interactions
edited by
submission deadline 30 Nov 2026 | 4 articles | Viewed by 3483 | Submission Open
Keywords: adaptation; Insecta; plant–insect interactions; life history; niche; coevolution; pollination; disease transmission; insect flight; metamorphosis; sociality
(This special issue belongs to the Section Ecology)
Role of Fibroblasts in Tissue Regeneration and Fibrosis submission deadline 30 Nov 2026 | 1 articles | Viewed by 3087 | Submission Open
Keywords: fibroblasts; tissue regeneration; fibrosis; cellular heterogeneity; extracellular matrix; cell signaling; mechanotransduction; omics; tissue remodeling; systems biology
(This special issue belongs to the Section Medical Biology)
The 1st International Online Conference on Biology—“Across Levels of Biological Organization” (Biology 2026)
edited by
submission deadline 30 Nov 2026 | 1 articles | Viewed by 2372 | Submission Open
Keywords: biological complexity; climate change; global biodiversity; host-parasite interactions; plant adaptations
Exploring the Molecular Basis of Cancer: Perspectives from Genetics and Epigenetics
edited by
submission deadline 30 Nov 2026 | 1 articles | Viewed by 2330 | Submission Open
Keywords: cancer genetics; epigenetics; tumor heterogeneity; histone modification; next-generation sequencing (NGS); cancer transcriptomics; gene regulation; mouse model; chromatin remodeling; CHIP-Seq; ATAC-seq; mutation; amplification
(This special issue belongs to the Section Genetics and Genomics)
Biological Foundations of Psychiatric Disorders
edited by Rammohan Shukla
submission deadline 30 Nov 2026 | 1 articles | Viewed by 1962 | Submission Open
Keywords: psychiatric disorders; molecular mechanisms; animal models; therapeutic discovery; genetic associations; sex differences; protocols; methods; behavioral studies; stress-related phenotypes
(This special issue belongs to the Section Neuroscience)
Machine Learning and AI Approaches for Genomic and Transcriptomic Insights in Health and Disease
edited by
submission deadline 30 Nov 2026 | 2 articles | Viewed by 1768 | Submission Open
Keywords: AI applications in biology and medicine; deep learning approaches in multiomic data integration and analysis; DNA/protein language modeling; computational genomics; AI-driven disease modeling
(This special issue belongs to the Section Bioinformatics)
Host–Pathogen Interactions: Mechanisms of Infection, Immune Evasion, and Novel Therapeutic Strategies submission deadline 30 Nov 2026 | 1 articles | Viewed by 752 | Submission Open
Keywords:

Host– pathogen interactions;

Immune evasion mechanisms;

Innate and adaptive immunity;

Microbial pathogenesis;

Immunomodulation;

Host-directed therapies;

Vaccine development;

Antimicrobial and antiviral strategies;

(This special issue belongs to the Section Immunology)
Current Research in the Biodiversity, Ecology, and Evolution of Chondrichthyan Fishes (Sharks, Rays and Chimaeras)
edited by , and João Paulo Capretz Batista da Silva
submission deadline 30 Nov 2026 | Viewed by 731 | Submission Open
Keywords: Chondrichthyes; Elasmobranchii; Holocephali; sharks; skates; rays; chimaeras; chimaeras; biodiversity; taxonomy; systematics; ecology; evolution
(This special issue belongs to the Section Marine and Freshwater Biology)
Integrative Immunology of the Skin: Unraveling Molecular Networks in Allergy, Autoimmunity, and Inflammation
edited by and
submission deadline 30 Nov 2026 | Viewed by 641 | Submission Open
Keywords: skin immunology; allergy and autoimmunity; chronic inflammation; cytokine and molecular networks; neuroimmune and microbiome interactions; systems immunology; multi-omics and spatial biology
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Redox-Active Phytochemicals as Modulators of ROS, RNS and RSS Signaling: From Molecular Mechanisms to Therapeutic Potential submission deadline 30 Nov 2026 | Viewed by 340 | Submission Open
Keywords: phytochemicals; bioactive compounds; medicinal plants; redox signaling; reactive oxygen species (ROS); reactive nitrogen species (RNS); reactive sulfur species (RSS); antioxidant mechanisms; redox modulation; hormesis; Nrf2 pathway; oxidative stress; natural products; nutraceuticals; health and disease
(This special issue belongs to the Section Plant Science)
Stem Cell Stress Responses: Mechanisms, Models, and Implications
edited by Taku Kaitsuka
submission deadline 30 Nov 2026 | Viewed by 315 | Submission Open
Keywords: stem cells; stress response; differentiation; heat stress; hypoxic stress; oxidative stress; mechanical stress; proteotoxic stress; membrane protein; stress-inducible transcription factor
(This special issue belongs to the Section Cell Biology)
Pathophysiology of Chronic Inflammatory Diseases
edited by Vincent Yuan
submission deadline 1 Dec 2026 | 5 articles | Viewed by 13440 | Submission Open
Keywords: chronic inflammation; autoimmune diseases; cytokines; inflammasome; metabolic dysfunction; oxidative stress; biomarkers; epigenetics; personalized medicine; therapeutic targets
(This special issue belongs to the Section Physiology)
Interactions and Cross-Kingdom Regulation of Hosts and Pathogens/Parasites
edited by and Jianfeng Qiu
submission deadline 1 Dec 2026 | 2 articles | Viewed by 1931 | Submission Open
Keywords: host; pathogen; parasite; interaction; cross-kingdom regulation; immune response; infection
(This special issue belongs to the Section Microbiology)
Sustainable Waste Management: Application of Biotechnology to Reduce Waste
edited by and Hande Ermis
submission deadline 1 Dec 2026 | 1 articles | Viewed by 1490 | Submission Open
Keywords: sustainable waste management; environmental biotechnology; microbial waste treatment; bioresource valorization; circular economy; waste-to-energy; bioreactors and bioprocesses; enzymatic degradation; industrial and municipal waste treatment
(This special issue belongs to the Section Biotechnology)
Neural and Non-Neural Substrates of Behavior
edited by
submission deadline 1 Dec 2026 | Viewed by 325 | Submission Open
Keywords: neural substrate; non-neural substrate; neural network; learning and memory; information processing; behavior
(This special issue belongs to the Section Neuroscience)
Environmental DNA (eDNA) for Assessment of Coastal Marine Biodiversity submission deadline 15 Dec 2026 | 7 articles | Viewed by 9384 | Submission Open
Keywords: eDNA metabarcoding; coastal marine ecosystems; biodiversity; genetic distances; ecological indicators
(This special issue belongs to the Section Ecology)
Bacterial Secretion Systems: Mechanisms, Regulation, and Their Roles in Microbe–Microbe and Microbe–Host Interactions
edited by
submission deadline 15 Dec 2026 | 1 articles | Viewed by 1412 | Submission Open
Keywords: secretion system; pathogenicity; quorum sensing; expression and regulation; transcriptomics; environmental adaptability; microbial interaction mechanism
(This special issue belongs to the Section Microbiology)
Young Researchers in Marine and Freshwater Biology
edited by
submission deadline 15 Dec 2026 | 1 articles | Viewed by 1257 | Submission Open
Keywords: aquatic ecology; aquatic physiology; aquatic ecosystems; aquatic species adaptation and evolution; aquatic biodiversity; aquatic mammals; aquatic top predators; aquatic invertebrates; aquatic symbioses; aquatic genetics; aquatic microbiology; limnology; biological oceanography; aquatic conservation; protection and sustainable exploitation
(This special issue belongs to the Section Marine and Freshwater Biology)
Recent Advances in Understanding Systemic Lupus Erythematosus Pathogenesis
edited by Rohit Upadhyay
submission deadline 15 Dec 2026 | Viewed by 881 | Submission Open
Keywords: systemic lupus erythematosus (SLE); autoimmunity; immune dysregulation; B and T cell biology; interferon signaling; autoantibodies; epigenetics; biomarkers; therapeutic targets; systems immunology
(This special issue belongs to the Section Medical Biology)
Genetic and Molecular Determinants of Chemical-Induced Genotoxicity and Oxidative Stress
edited by Tanima SenGupta and
submission deadline 15 Dec 2026 | Viewed by 202 | Submission Open
Keywords: DNA repair; DNA damage; ROS; mitochondrial dysfunction; genotoxicity; neurotoxicity; aging; cancer; nanomedicine; toxicology; endocrine disruption
(This special issue belongs to the Section Toxicology)
Biology of Liver Diseases submission deadline 20 Dec 2026 | 6 articles | Viewed by 24557 | Submission Open
Keywords: viral hepatitis; alcoholic hepatitis; non-alcoholic steatohepatitis; autoimmune hepatitis; primary biliary cholangitis; liver cirrhosis; liver cancer; portal hypertension
(This special issue belongs to the Section Medical Biology)
Impacts of Climate Change on Terrestrial Carbon Cycling and Biodiversity Across Spatial and Temporal Scales submission deadline 21 Dec 2026 | 4 articles | Viewed by 7588 | Submission Open
Keywords: climate change; terrestrial carbon cycling; biodiversity; spatial and temporal scales; ecosystem resilience; UN CBD; UN Decade on Ecosystem Restoration; responsible business; nature-based solutions; sustainable development
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Genetic Adaptation and Yield Optimization in Soybean Cultivation
edited by Glauco Vieira Miranda
submission deadline 25 Dec 2026 | 1 articles | Viewed by 681 | Submission Open
Keywords: soybean breeding; genetic adaptation; genotype × environment interaction; genomic prediction; enviromics; multi-environment trials; climate resilience; yield stability; artificial intelligence in agriculture; crop improvement
(This special issue belongs to the Section Plant Science)
Advances in Tropical and Subtropical Plant Ecology and Physiology
edited by Naysa Flávia Ferreira Do Nascimento and Edna Ursulino Alves
submission deadline 30 Dec 2026 | 6 articles | Viewed by 8534 | Submission Open
Keywords: tropical plants; plant ecology; plant physiology; environmental adaptations; phenotypic diversity; climate change; biodiversity conservation; sustainable management
(This special issue belongs to the Section Plant Science)
The Neurobiology of Sleep and Circadian Clock
edited by
submission deadline 30 Dec 2026 | 1 articles | Viewed by 5494 | Submission Open
Keywords: clock genes; neuroendocrine rhythms; circadian misalignment; sleep disorders; sleep health; light; jet lag; shift work
(This special issue belongs to the Section Neuroscience)
Neuroprotective Strategies in Preclinical Animal Models of Neurological Disorders
edited by Lucia Buccarello
submission deadline 30 Dec 2026 | 2 articles | Viewed by 2426 | Submission Open
Keywords: neuroprotective strategies; intracellular signaling pathways; synaptic dysfunction; oxidative stress: neuronal/cell death; preclinical animal models; neurodegeneration; microglia–neuron interaction; neurotrophin signaling; natural compounds
(This special issue belongs to the Section Neuroscience)
Feature Papers in Immunology submission deadline 30 Dec 2026 | 2 articles | Viewed by 1960 | Submission Open
Keywords: immune regulation and signaling networks; host–pathogen interactions; innate and adaptive immune responses; immunometabolism and metabolic control of immunity; tumor immunology and immune evasion; autoimmunity and inflammatory diseases; immune modulation and therapeutic targeting; microenvironmental regulation of immune function; molecular and cellular mechanisms of immunity; multi-omics and systems immunology approaches
(This special issue belongs to the Section Immunology)
Advances in Immunomodulation for Inflammatory Diseases
edited by
submission deadline 30 Dec 2026 | 1 articles | Viewed by 965 | Submission Open
Keywords: immunomodulation; inflammatory diseases; inflammasome; immune homeostasis; innate immunity; adaptive immunity; signaling pathways; immune regulation; chronic inflammation; autoimmunity; cytokines
(This special issue belongs to the Section Immunology)
Perspective of Signal Transduction in Cancer and Inflammation
edited by and Araceli Perez-Lopez
submission deadline 30 Dec 2026 | Viewed by 556 | Submission Open
Keywords: immuno-oncology; tumor microenvironment; signal transduction; cytokines; JAK/STAT; NF-κB; inflammasome; T-cell dysfunction; myeloid reprogramming; biomarkers
(This special issue belongs to the Section Immunology)
Advances and Perspectives in RNA Modifications and Non-Coding RNAs
edited by
submission deadline 30 Dec 2026 | Viewed by 399 | Submission Open
Keywords: tRNA biology; tRNA modifications; sequencing; translational control; codon decoding; tRNA fragments; RNA structure; ribosome dynamics; RNA-based regulation; disease mechanisms
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Biology, Pathogenesis, and Genomics of Animal Viruses
edited by Andrea Elizabeth Verna
submission deadline 30 Dec 2026 | Viewed by 376 | Submission Open
Keywords: animal viruses; molecular virology; viral genomics; host–virus interactions; viral pathogenesis; innate immunity; comparative genomics; One Health; emerging viruses
(This special issue belongs to the Section Microbiology)
Translational Kidney Injury Models: From Rodents to Organoids, Precision-Cut Slices, and Microphysiologic Systems
edited by
submission deadline 30 Dec 2026 | Viewed by 358 | Submission Open
Keywords: acute kidney injury; chronic kidney disease; AKI–CKD transition; animal models; precision-cut kidney slices; kidney organoids; microphysiologic systems/organ on chip; renal fibrosis; nephrotoxicity; translational nephrology
(This special issue belongs to the Section Medical Biology)
Molecular Mechanisms of Plant Immunity and Plant–Pathogen Interactions
edited by
submission deadline 30 Dec 2026 | Viewed by 308 | Submission Open
Keywords: plant pathogen; disease; molecular mechanisms; plant immunity; microbes
(This special issue belongs to the Section Plant Science)
Physiological, Biochemical, and Molecular Response in Plants under Light-Emitting Diode (LED) Treatment (Volume II) submission deadline 31 Dec 2026 | 9 articles | Viewed by 34417 | Submission Open
Keywords: antioxidants; bioactive compounds; biotic and abiotic stress; food quality; LED; nutrients; plant defense; plant response; productivity
(This special issue belongs to the Section Plant Science)
The Potential of Genetics and Plant Breeding in Crop Improvement submission deadline 31 Dec 2026 | 17 articles | Viewed by 21526 | Submission Open
Keywords: plants; plant signaling pathways; growth and development; genomics; transcriptomics; proteomics; metabolomics; gene transformation; molecular biology; biochemistry; molecular breeding; genome editing; CRISPR/Cas9; marker-assisted selection; genome-wide selection; crop improvement; genetic diversity; quality traits; yield; disease resistance; environmental stress; plant-microbe interactions; drought tolerance; salinity resistance; oxidative stress; phytohormone
(This special issue belongs to the Section Plant Science)
Advances in Aquatic Ecological Disasters and Toxicology
edited by and
submission deadline 31 Dec 2026 | 13 articles | Viewed by 18787 | Submission Open
Keywords: aquatic ecological disasters; aquatic toxicology; aquatic ecosystem; algal blooms; pollutants
State of the Art in Fish Nutrition: Antimicrobials, Immunostimulants, Synbiotics and Alternative Protein Sources
edited by Jiun-Yan Loh
submission deadline 31 Dec 2026 | 6 articles | Viewed by 17380 | Submission Open
Keywords: probiotics; prebiotics; synbiotics; immunostimulants; antimicrobial peptides; alternative protein/single-cell protein sources; insect meals; aquatic species; metabolisms; disease resistances
(This special issue belongs to the Section Zoology)
Young Investigators in Biochemistry and Molecular Biology
edited by
submission deadline 31 Dec 2026 | 9 articles | Viewed by 15506 | Submission Open
Keywords: protein structure and function; DNA Methylation; apoptosis; computational biology; molecular development biology; molecular enzymology; molecular evolution; molecular immunology; molecular virology; systems biology; proteins and nucleic acids; protein trafficking; proteomics; structural and functional genomics; transcriptomics; signaling
(This special issue belongs to the Section Biochemistry and Molecular Biology)
15 Years of Biology: The View Ahead
edited by
submission deadline 31 Dec 2026 | 12 articles | Viewed by 14691 | Submission Open
Keywords: behavioral biology; bioinformatics; biophysics; biotechnology; cancer biology; cell biology; conservation biology and biodiversity; developmental and reproductive biology; ecology; evolutionary biology; genetics and genomics; immunology; infection biology; marine and freshwater biology; medical biology; microbiology; neuroscience; physiology; plant science; toxicology; theoretical biology and biomathematics; zoology
Biology, Ecology and Management of Aquatic Macrophytes and Algae—2nd Edition
edited by , and
submission deadline 31 Dec 2026 | 10 articles | Viewed by 13399 | Submission Open
Keywords: aquatic macrophytes and algae; ecological planning and management; harmful algal blooms and control; biological resources and environment; aquatic ecosystem stability; ecological restoration; biodiversity; plant physiology; biomarkers; symbiotic microorganisms
Advances in Research on Diseases of Plants (2nd Edition)
edited by
submission deadline 31 Dec 2026 | 7 articles | Viewed by 12750 | Submission Open
Keywords: phytopathogen; plant immunity; plant disease resistance; gene expression/regulation; signal regulation; pathogenesis; virulence; genetic engineering; disease control
(This special issue belongs to the Section Plant Science)
Mechanisms of Genetic and Epigenetic Regulation Underlying Plant Resistance
edited by Feng Zhang, and
submission deadline 31 Dec 2026 | 11 articles | Viewed by 11128 | Submission Open
Keywords: plant biotic and abiotic stresses; multi-omics; genetic engineering; genome editing; epigenetic regulation
(This special issue belongs to the Section Plant Science)
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