The Role of Lipids in Cardiovascular and Neurodegenerative Diseases
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Biochemistry and Molecular Biology".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 381
Special Issue Editors
Interests: metabolomics; lipidomics; analytical chemistry
2. National & Local Joint Engineering Research Center for the Exploitation of Homology Resources of Medicine and Food, Guizhou University, Guiyang 550025, China
Interests: metabolomics; food safety; health; lipidomics
Special Issue Information
Dear Colleagues,
Lipid molecules, including glycerolipids, glycerophospholipids, sterol lipids, and other classes, are fundamental for both physiological processes and disease mechanisms. In cardiovascular diseases, dysregulated lipid metabolism is a key driver of atherosclerosis, leading to conditions such as heart attacks and strokes. The balance between LDL and HDL cholesterol, along with the inflammatory responses triggered by lipid accumulation, highlights the complexity of lipid involvement in cardiovascular health.
Similarly, in neurodegenerative diseases like Alzheimer’s disease and Parkinson’s disease, lipids play crucial roles in maintaining neuronal structure and function. Dysregulation of lipid homeostasis, particularly involving cholesterol and lipid rafts, contributes to the formation of pathological aggregates, neuroinflammation, and oxidative stress, accelerating neuronal damage and disease development.
This Special Issue gathers the latest research on the roles of lipid molecules in these diseases, offering insights into the underlying mechanisms and potential therapeutic targets. By exploring the intersections between lipid biology, cardiovascular science, and neurodegeneration, we aim to foster a deeper understanding of lipid biology and inspire new strategies for the prevention and treatment of these diseases.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: lipid biology, lipid peroxidation, lipidomics, lipid foods or nutrients, cardiovascular disease, and neurodegenerative diseases.
We look forward to receiving your contributions.
Dr. Yuanyuan Ji
Dr. Ronghui Gu
Dr. Yaxin Li
Guest Editors
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Keywords
- lipid biology
- lipid peroxidation
- lipidomics
- lipid foods or nutrients
- cardiovascular disease
- neurodegenerative diseases
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