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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Coral Physiological Plasticity and Environmental Adaptation: From Molecular Mechanisms to Ecosystem Resilience

edited by

Jennifer L. Matthews

submission deadline 30 Sep 2026 | Submission Open

Keywords: environmental stressors; physiological plasticity; climate resilience; molecular mechanisms; coral symbiosis; adaptive potential; ocean acidification; thermal tolerance

(This special issue belongs to the Section Marine and Freshwater Biology)

Pollination Biology: 2nd Edition

edited by

Yu Gao

and

Bartosz Płachno

submission deadline 1 Oct 2026 | Viewed by 120 | Submission Open

Keywords: conservation biology; insect diversity; pollinator-plant interactions; ecosystem service; pollinating insect; flower; bee

(This special issue belongs to the Section Ecology)

Semaphorins as Drivers of Inflammatory Disease: Setting Immune Cells in Motion

edited by

Tiago Granja

submission deadline 3 Oct 2026 | Viewed by 57 | Submission Open

Keywords: semaphorins; inflammation; neuronal guidance proteins; soluble guidance cues; cell motility; cytoskeletal dynamics; extracellular matrix

(This special issue belongs to the Section Immunology)

Multi-omics Approaches in Agricultural Crops to Unravel Responses to Environmental Stresses and Advance Sustainable Agriculture

edited by

Vito Butardo

submission deadline 30 Oct 2026 | 2 articles | Viewed by 5688 | Submission Open

Keywords: plant functional genomics; environmental stress; climate change; crop yield; crop quality; nutritional properties; omics approaches; genomics; transcriptomics; proteomics; metabolomics; epigenomics; phenomics; stress-tolerant crops; breeding strategies; data integration; systems biology; sustainable agriculture; underutilized crops; orphan crops; beneficial microorganisms

(This special issue belongs to the Section Plant Science)

Pathophysiology of Hearing Loss

edited by Charles E. Bishop

submission deadline 30 Oct 2026 | 2 articles | Viewed by 1130 | Submission Open

Keywords: hearing loss; cochlea; noise; deafness genes; cell death; hair cells; inner ear; biotoxicity; metabolic risk; gene mutation; physiology and pathophysiology; animal models; biomarkers and molecular mechanisms

(This special issue belongs to the Section Physiology)

Molecular, Biophysical, and Neurophysiological Mechanisms Underlying Magnetoreception

edited by

Weidong Pan

and

Guijun Wan

submission deadline 30 Oct 2026 | Viewed by 153 | Submission Open

Keywords: earth magnetic field; magnetosensing; magnetite; radical pair; orientation; navigation; magnetic receptor; electroreceptor; neurophysiology

Animal Virus–Host Interactions and Cross-Species Dynamics

edited by

Anan Jongkaewwattana

and

Thanathom Chailangkarn

submission deadline 30 Oct 2026 | Viewed by 104 | Submission Open

Keywords: animal viruses; zoonosis; pathogenesis; host immunity; vaccines; antivirals; host– pathogen interaction; One Health; veterinary virology

(This special issue belongs to the Section Infection Biology)

Fatty Acid Metabolism and Inflammation

edited by

Mi-hee Park

submission deadline 30 Oct 2026 | Viewed by 80 | Submission Open

Keywords: fatty acid metabolism; metabolic dysfunction; mitochondrial impairment; oxidative stress; glucose metabolism; lipid metabolism; Immune modulation; Inflammation; biomarkers

(This special issue belongs to the Section Physiology)

Advances in Zebrafish as an Experimental Model: From Husbandry to Cutting-Edge Applications

edited by Rosario Moyano-Salvago,

Rafael Mora Medina

and

Nahúm Ayala-Soldado

submission deadline 30 Oct 2026 | Viewed by 34 | Submission Open

Keywords: zebrafish; experimental model; developmental biology; genetics; gene editing; transgenesis; toxicology; regeneration; animal welfare; biomedical research

(This special issue belongs to the Section Zoology)

Immunosenescence and Its Modification by Interventions

edited by

Andreas Meryk

and Luca Pangrazzi

submission deadline 31 Oct 2026 | 1 articles | Viewed by 6254 | Submission Open

Keywords: immunosenescence; aging immune system; inflammaging; vaccine efficacy in elderly; nutritional immunomodulation; exercise and immunity; senolytic therapies; T-cell exhaustion; thymic rejuvenation; age-related diseases

(This special issue belongs to the Section Immunology)

Mitochondria and Cardiovascular Diseases

edited by Qingxun Hu

submission deadline 31 Oct 2026 | 1 articles | Viewed by 3110 | Submission Open

Keywords: cardiovascular diseases; mitochondria; pathophysiology; cardiology; cell metabolism; animal models; epigenetics; redox biology

(This special issue belongs to the Section Physiology)

Advances in Plant Multi-Omics

edited by

Xiuzhang Li

, Zhonglong Guo and Xuekai Wei

submission deadline 31 Oct 2026 | 1 articles | Viewed by 597 | Submission Open

Keywords: multi-omics integration; plant systems biology; high-throughput sequencing; bioinformatics integration; stress response

(This special issue belongs to the Section Plant Science)

Transcriptional Regulation in Eukaryotes

edited by Anil Kumar Panigrahi

submission deadline 31 Oct 2026 | Viewed by 527 | Submission Open

Keywords: transcription factors (TFs); transcriptional coregulators; RNA polymerase II; chromatin modifications and remodeling; enhancers; silencers; non-coding RNAs; 3D chromatin architecture; multi-omics integration; single-cell technologies

(This special issue belongs to the Section Genetics and Genomics)

Brain Organoids: Construction, Analysis, and Application

edited by

Jonghun Kim

submission deadline 31 Oct 2026 | Viewed by 221 | Submission Open

Keywords: brain organoids; iPSCs; neurodevelopmental disorders; region-specific organoids; functional neuronal analysis

Decoding RNA Modifications in Cancer Biology

edited by Yutao Zhao

submission deadline 31 Oct 2026 | Viewed by 129 | Submission Open

Keywords: RNA modifications; epitranscriptomics; gene regulation; RNA biology; post-transcriptional regulation; N6-methyladenosine (m6A); pseudouridine (Ψ )

(This special issue belongs to the Section Cancer Biology)

Current Advances in Cancer Genomics

edited by

Yuanxiang Li

submission deadline 31 Oct 2026 | Viewed by 90 | Submission Open

Keywords: cancer genomics; tumor heterogeneity; epigenomics; single-cell sequencing; multi-omics; genomic biomarkers; precision oncology; computational genomics; non-coding RNA; drug resistance

(This special issue belongs to the Section Cancer Biology)

Pathogenesis and Immune Evasion of Mycobacteria in Mammals

edited by Federico Carlos Blanco and Cristina Lourdes Vázquez

submission deadline 31 Oct 2026 | Viewed by 77 | Submission Open

Keywords: mycobacteria; pathogenesis; immune evasion; host– pathogen interactions; latency; zoonotic transmission; comparative immunology; vaccine development; host-directed therapies

(This special issue belongs to the Section Immunology)

Molecular Mechanisms of AHPND: From Pathogen Virulence to Host Immunity

edited by

Sonia A. Soto-Rodriguez

submission deadline 31 Oct 2026 | Viewed by 44 | Submission Open

Keywords: AHPND; Vibrio; pathogenesis; host immunity; shrimp disease; aquaculture; virulence mechanisms; omics

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Research Advances on Biology and Genetics of Bees

edited by

Jiaxing Huang

and

Guiling Ding

submission deadline 31 Oct 2026 | Viewed by 27 | Submission Open

Keywords: bee biology; pollination ecology; environmental stressors; bee genomics and omics; bee health and conservation; foraging behavior and social organization

(This special issue belongs to the Section Zoology)

Reproduction Under the Microscope: From Oocyte Architecture to Reproductive Function

edited by

Manuel Belli

submission deadline 1 Nov 2026 | Submission Open

Keywords: reproductive biology; oocyte; gametogenesis; fertilization; embryonic development; electron microscopy; ultrastructure; reproductive pathology

Genetics and Evolutionary Biology of Aquatic Organisms

edited by

Qianhong Gu

and Liang Guo

submission deadline 15 Nov 2026 | 3 articles | Viewed by 1678 | Submission Open

Keywords: population genetics; conservation genetics; biodiversity; comparative genomics; polyploidization; rapid adaptation; population genetic divergence; thermal tolerance; hypoxia adaptation; deep-sea pressure adaptation; convergent evolution; molecular clock; phylogeography; population genetic structure; divergence time; inbreeding depression; genetic diversity; genomic selection; genome assembly; transcriptomics; population genomics

(This special issue belongs to the Section Evolutionary Biology)

Erythrocytes in Human Life—Functions Beyond Oxygen Transport

edited by

Vesna Ilic

and

Ivana Drvenica

submission deadline 15 Nov 2026 | Viewed by 170 | Submission Open

Keywords: erythrocytes in physiological processes; erythrocytes in disease pathophysiology; erythrocyte biomechanics; erythrocyte imaging; erythrocyte membrane; erythrocyte metabolism; haemoglobin; immune modulation; redox homeostasis

(This special issue belongs to the Section Cell Biology)

Regulatory Mechanisms of Plant Stress Response

edited by

Yuxuan Hou

and Li Ren

submission deadline 30 Nov 2026 | 3 articles | Viewed by 5206 | Submission Open

Keywords: gene; gene expression; gene function; molecular regulation; genetic resource; phenotype; stress response

(This special issue belongs to the Section Genetics and Genomics)

Physiology and Pathophysiology of the Kidney

edited by Gang Liu

submission deadline 30 Nov 2026 | 3 articles | Viewed by 4976 | Submission Open

Keywords: renal physiology; renal hemodynamics; kidney injury; regenerative therapies; urology

(This special issue belongs to the Section Physiology)

The 1st International Online Conference on Biology—“Across Levels of the Biological Organization” (Biology 2025)

edited by

Andrés Moya

submission deadline 30 Nov 2026 | Viewed by 410 | Submission Open

Keywords: biological complexity; climate change; global biodiversity; host-parasite interactions; plant adaptations

Current Research in the Biodiversity, Ecology, and Evolution of Chondrichthyan Fishes (Sharks, Rays and Chimaeras)

edited by

Simon Weigmann

Diego F.B. Vaz

and João Paulo Capretz Batista da Silva

submission deadline 30 Nov 2026 | Viewed by 406 | Submission Open

Keywords: Chondrichthyes; Elasmobranchii; Holocephali; sharks; skates; rays; chimaeras; chimaeras; biodiversity; taxonomy; systematics; ecology; evolution

(This special issue belongs to the Section Marine and Freshwater Biology)

Exploring the Molecular Basis of Cancer: Perspectives from Genetics and Epigenetics

edited by

Shilpa Dhar

submission deadline 30 Nov 2026 | Viewed by 393 | Submission Open

Keywords: cancer genetics; epigenetics; tumor heterogeneity; histone modification; next-generation sequencing (NGS); cancer transcriptomics; gene regulation; mouse model; chromatin remodeling; CHIP-Seq; ATAC-seq; mutation; amplification

(This special issue belongs to the Section Genetics and Genomics)

Biological Foundations of Psychiatric Disorders

edited by Rammohan Shukla

submission deadline 30 Nov 2026 | Viewed by 256 | Submission Open

Keywords: psychiatric disorders; molecular mechanisms; animal models; therapeutic discovery; genetic associations; sex differences; protocols; methods; behavioral studies; stress-related phenotypes

(This special issue belongs to the Section Neuroscience)

Stem Cell Stress Responses: Mechanisms, Models, and Implications

edited by Taku Kaitsuka

submission deadline 30 Nov 2026 | Viewed by 98 | Submission Open

Keywords: stem cells; stress response; differentiation; heat stress; hypoxic stress; oxidative stress; mechanical stress; proteotoxic stress; membrane protein; stress-inducible transcription factor

(This special issue belongs to the Section Cell Biology)

Ecological Dynamics of Vector-Borne Pathogens: From Hosts to Vectors

edited by

Sofia Ferreira Anastácio

Joana Ferrolho Gibson

and Hugo C. R. Vilhena

submission deadline 30 Nov 2026 | Viewed by 96 | Submission Open

Keywords: vector-borne pathogens; host– vector interactions; climate change; disease emergence

(This special issue belongs to the Section Microbiology)

Neurodegeneration: Pathways and Mechanisms

edited by

Ferdinando Franzoni

and

Giorgia Scarfò

submission deadline 30 Nov 2026 | Viewed by 57 | Submission Open

Keywords: inflammation; oxidative stress; apoptosis; exercise; diet; cellular pathways

(This special issue belongs to the Section Neuroscience)

New Perspectives of Immunity Against SARS-CoV-2

edited by

Jorge A. Soto

and

Felipe Melo-González

submission deadline 30 Nov 2026 | Viewed by 49 | Submission Open

Keywords: innate and adaptive immune responses; viral immune evasion; mucosal and systemic immunity; vaccine-induced protection; host– pathogen interactions; immunomodulation and antiviral strategies

(This special issue belongs to the Section Immunology)

Machine Learning and AI Approaches for Genomic and Transcriptomic Insights in Health and Disease

edited by

Sushil Shakyawar

submission deadline 30 Nov 2026 | Submission Open

Keywords: AI applications in biology and medicine; deep learning approaches in multiomic data integration and analysis; DNA/protein language modeling; computational genomics; AI-driven disease modeling

(This special issue belongs to the Section Bioinformatics)

Redox-Active Phytochemicals as Modulators of ROS, RNS and RSS Signaling: From Molecular Mechanisms to Therapeutic Potential

edited by

Lucas Fornari Laurindo

submission deadline 30 Nov 2026 | Submission Open

Keywords: phytochemicals; bioactive compounds; medicinal plants; redox signaling; reactive oxygen species (ROS); reactive nitrogen species (RNS); reactive sulfur species (RSS); antioxidant mechanisms; redox modulation; hormesis; Nrf2 pathway; oxidative stress; natural products; nutraceuticals; health and disease

(This special issue belongs to the Section Plant Science)

Pathophysiology of Chronic Inflammatory Diseases

edited by Vincent Yuan

submission deadline 1 Dec 2026 | 4 articles | Viewed by 6326 | Submission Open

Keywords: chronic inflammation; autoimmune diseases; cytokines; inflammasome; metabolic dysfunction; oxidative stress; biomarkers; epigenetics; personalized medicine; therapeutic targets

(This special issue belongs to the Section Physiology)

Neural and Non-Neural Substrates of Behavior

edited by

Sam Zheng

submission deadline 1 Dec 2026 | Submission Open

Keywords: neural substrate; non-neural substrate; neural network; learning and memory; information processing; behavior

(This special issue belongs to the Section Neuroscience)

Recent Advances in Understanding Systemic Lupus Erythematosus Pathogenesis

edited by Rohit Upadhyay

submission deadline 15 Dec 2026 | Viewed by 326 | Submission Open

Keywords: systemic lupus erythematosus (SLE); autoimmunity; immune dysregulation; B and T cell biology; interferon signaling; autoantibodies; epigenetics; biomarkers; therapeutic targets; systems immunology

(This special issue belongs to the Section Medical Biology)

Bacterial Secretion Systems: Mechanisms, Regulation, and Their Roles in Microbe–Microbe and Microbe–Host Interactions

edited by

Lingfang Zhu

submission deadline 15 Dec 2026 | Viewed by 76 | Submission Open

Keywords: secretion system; pathogenicity; quorum sensing; expression and regulation; transcriptomics; environmental adaptability; microbial interaction mechanism

(This special issue belongs to the Section Microbiology)

Biology of Liver Diseases

edited by

Tadashi Namisaki

and

Hiroaki Takaya

submission deadline 20 Dec 2026 | 4 articles | Viewed by 13110 | Submission Open

Keywords: viral hepatitis; alcoholic hepatitis; non-alcoholic steatohepatitis; autoimmune hepatitis; primary biliary cholangitis; liver cirrhosis; liver cancer; portal hypertension

(This special issue belongs to the Section Medical Biology)

Impacts of Climate Change on Terrestrial Carbon Cycling and Biodiversity Across Spatial and Temporal Scales

edited by

Nophea Sasaki

and

Takuji W. Tsusaka

submission deadline 21 Dec 2026 | 4 articles | Viewed by 2877 | Submission Open

Keywords: climate change; terrestrial carbon cycling; biodiversity; spatial and temporal scales; ecosystem resilience; UN CBD; UN Decade on Ecosystem Restoration; responsible business; nature-based solutions; sustainable development

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Advances in Tropical and Subtropical Plant Ecology and Physiology

edited by Naysa Flávia Ferreira Do Nascimento and Edna Ursulino Alves

submission deadline 30 Dec 2026 | 4 articles | Viewed by 1281 | Submission Open

Keywords: tropical plants; plant ecology; plant physiology; environmental adaptations; phenotypic diversity; climate change; biodiversity conservation; sustainable management

(This special issue belongs to the Section Plant Science)

Feature Papers in Immunology

edited by

Natalia Osna

and

Anup Singh Pathania

submission deadline 30 Dec 2026 | Viewed by 11 | Submission Open

Keywords: immune regulation and signaling networks; host– pathogen interactions; innate and adaptive immune responses; immunometabolism and metabolic control of immunity; tumor immunology and immune evasion; autoimmunity and inflammatory diseases; immune modulation and therapeutic targeting; microenvironmental regulation of immune function; molecular and cellular mechanisms of immunity; multi-omics and systems immunology approaches

(This special issue belongs to the Section Immunology)

Biology, Pathogenesis, and Genomics of Animal Viruses

edited by Andrea Elizabeth Verna

submission deadline 30 Dec 2026 | Submission Open

Keywords: animal viruses; molecular virology; viral genomics; host– virus interactions; viral pathogenesis; innate immunity; comparative genomics; One Health; emerging viruses

(This special issue belongs to the Section Microbiology)

Neuroprotective Strategies in Preclinical Animal Models of Neurological Disorders

edited by Lucia Buccarello

submission deadline 30 Dec 2026 | Submission Open

Keywords: neuroprotective strategies; intracellular signaling pathways; synaptic dysfunction; oxidative stress: neuronal/cell death; preclinical animal models; neurodegeneration; microglia– neuron interaction; neurotrophin signaling; natural compounds

(This special issue belongs to the Section Neuroscience)

Biology, Ecology and Management of Aquatic Macrophytes and Algae—2nd Edition

edited by

Jinlin Liu

Wei Liu

and Shuang Zhao

submission deadline 31 Dec 2026 | 5 articles | Viewed by 5473 | Submission Open

Keywords: aquatic macrophytes and algae; ecological planning and management; harmful algal blooms and control; biological resources and environment; aquatic ecosystem stability; ecological restoration; biodiversity; plant physiology; biomarkers; symbiotic microorganisms

Aquatic Economic Animal Breeding and Healthy Farming (2nd Edition)

edited by Yude Wang and Shengwei Luo

submission deadline 31 Dec 2026 | 1 articles | Viewed by 588 | Submission Open

Keywords: rice– fish; fish; and aquaculture; hybridization and genetic breeding; nutrient additive and requirement; physiology and immune response; disease control; pathogenesis research; probiotic identification and function; transcriptomics; proteomics; metabonomics

(This special issue belongs to the Section Zoology)

Cellular Senescence in Development, Regeneration, Aging, and Cancer

edited by

Selim Chaib

submission deadline 31 Dec 2026 | Viewed by 528 | Submission Open

Keywords: cellular senescence; aging; cancer; obesity; metabolism; geroscience; age-related diseases; SASP; senolytics; biomarkers

Metabolic and Stress Responses in Aquatic Animals (2nd Edition)

edited by

Marcelino Herrera

, Laura Fernández-Alacid and

Ignacio Ruiz-Jarabo

submission deadline 31 Dec 2026 | 1 articles | Viewed by 284 | Submission Open

Keywords: stress; metabolism; animal welfare; aquaculture; cephalopods; fish; molluscs; crustaceans; aquatic animals; animal physiology

(This special issue belongs to the Section Zoology)

Plant Developmental Transition Under Changing Climate

edited by Zeeshan Nasim

submission deadline 31 Dec 2026 | Viewed by 209 | Submission Open

Keywords: plant development; reproductive transition; flowering; climate change; global warming TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Ecology)

Advances in Biomechanics in Physiology and Pathology

edited by

Milan Toma

submission deadline 31 Dec 2026 | Viewed by 160 | Submission Open

Keywords: biomechanics; mechanics; extracellular matrix; cellular mechanics; tissue remodeling; developmental biomechanics; computational modeling; bioimaging; engineered microenvironments; artificial intelligence; machine learning

(This special issue belongs to the Section Biophysics)

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