Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Transcriptional Regulation in Eukaryotes
edited by Anil Kumar Panigrahi
submission deadline 31 Oct 2026 | Viewed by 545 | Submission Open
Keywords: transcription factors (TFs); transcriptional coregulators; RNA polymerase II; chromatin modifications and remodeling; enhancers; silencers; non-coding RNAs; 3D chromatin architecture; multi-omics integration; single-cell technologies
(This special issue belongs to the Section Genetics and Genomics)
Brain Organoids: Construction, Analysis, and Application
edited by
submission deadline 31 Oct 2026 | Viewed by 231 | Submission Open
Keywords: brain organoids; iPSCs; neurodevelopmental disorders; region-specific organoids; functional neuronal analysis
Decoding RNA Modifications in Cancer Biology
edited by Yutao Zhao
submission deadline 31 Oct 2026 | Viewed by 137 | Submission Open
Keywords: RNA modifications; epitranscriptomics; gene regulation; RNA biology; post-transcriptional regulation; N6-methyladenosine (m6A); pseudouridine (Ψ )
(This special issue belongs to the Section Cancer Biology)
Current Advances in Cancer Genomics
edited by
submission deadline 31 Oct 2026 | Viewed by 99 | Submission Open
Keywords: cancer genomics; tumor heterogeneity; epigenomics; single-cell sequencing; multi-omics; genomic biomarkers; precision oncology; computational genomics; non-coding RNA; drug resistance
(This special issue belongs to the Section Cancer Biology)
Pathogenesis and Immune Evasion of Mycobacteria in Mammals
edited by Federico Carlos Blanco and Cristina Lourdes Vázquez
submission deadline 31 Oct 2026 | Viewed by 97 | Submission Open
Keywords: mycobacteria; pathogenesis; immune evasion; host– pathogen interactions; latency; zoonotic transmission; comparative immunology; vaccine development; host-directed therapies
(This special issue belongs to the Section Immunology)
Molecular Mechanisms of AHPND: From Pathogen Virulence to Host Immunity submission deadline 31 Oct 2026 | Viewed by 54 | Submission Open
Keywords: AHPND; Vibrio; pathogenesis; host immunity; shrimp disease; aquaculture; virulence mechanisms; omics
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Research Advances on Biology and Genetics of Bees
edited by and
submission deadline 31 Oct 2026 | Viewed by 40 | Submission Open
Keywords: bee biology; pollination ecology; environmental stressors; bee genomics and omics; bee health and conservation; foraging behavior and social organization
(This special issue belongs to the Section Zoology)
Reproduction Under the Microscope: From Oocyte Architecture to Reproductive Function
edited by
submission deadline 1 Nov 2026 | Viewed by 19 | Submission Open
Keywords: reproductive biology; oocyte; gametogenesis; fertilization; embryonic development; electron microscopy; ultrastructure; reproductive pathology
Genetics and Evolutionary Biology of Aquatic Organisms
edited by and Liang Guo
submission deadline 15 Nov 2026 | 3 articles | Viewed by 1958 | Submission Open
Keywords: population genetics; conservation genetics; biodiversity; comparative genomics; polyploidization; rapid adaptation; population genetic divergence; thermal tolerance; hypoxia adaptation; deep-sea pressure adaptation; convergent evolution; molecular clock; phylogeography; population genetic structure; divergence time; inbreeding depression; genetic diversity; genomic selection; genome assembly; transcriptomics; population genomics
(This special issue belongs to the Section Evolutionary Biology)
Erythrocytes in Human Life—Functions Beyond Oxygen Transport
edited by and
submission deadline 15 Nov 2026 | Viewed by 182 | Submission Open
Keywords: erythrocytes in physiological processes; erythrocytes in disease pathophysiology; erythrocyte biomechanics; erythrocyte imaging; erythrocyte membrane; erythrocyte metabolism; haemoglobin; immune modulation; redox homeostasis
(This special issue belongs to the Section Cell Biology)
Regulatory Mechanisms of Plant Stress Response
edited by and Li Ren
submission deadline 30 Nov 2026 | 3 articles | Viewed by 5570 | Submission Open
Keywords: gene; gene expression; gene function; molecular regulation; genetic resource; phenotype; stress response
(This special issue belongs to the Section Genetics and Genomics)
Physiology and Pathophysiology of the Kidney
edited by Gang Liu
submission deadline 30 Nov 2026 | 3 articles | Viewed by 5158 | Submission Open
Keywords: renal physiology; renal hemodynamics; kidney injury; regenerative therapies; urology
(This special issue belongs to the Section Physiology)
Genetics and Cell Biology in Crop Improvement
edited by , , Jie Huang and Xixi Liu
submission deadline 30 Nov 2026 | 1 articles | Viewed by 2576 | Submission Open
Keywords: plant genomics and genetics; gene cloning and function; crop molecular breeding; germplasm enhancement; genetic engineering; plant cell biology; crop adaptability
(This special issue belongs to the Section Plant Science)
Current Research in the Biodiversity, Ecology, and Evolution of Chondrichthyan Fishes (Sharks, Rays and Chimaeras)
edited by , and João Paulo Capretz Batista da Silva
submission deadline 30 Nov 2026 | Viewed by 452 | Submission Open
Keywords: Chondrichthyes; Elasmobranchii; Holocephali; sharks; skates; rays; chimaeras; chimaeras; biodiversity; taxonomy; systematics; ecology; evolution
(This special issue belongs to the Section Marine and Freshwater Biology)
The 1st International Online Conference on Biology—“Across Levels of the Biological Organization” (Biology 2025)
edited by
submission deadline 30 Nov 2026 | Viewed by 446 | Submission Open
Keywords: biological complexity; climate change; global biodiversity; host-parasite interactions; plant adaptations
Exploring the Molecular Basis of Cancer: Perspectives from Genetics and Epigenetics
edited by
submission deadline 30 Nov 2026 | Viewed by 414 | Submission Open
Keywords: cancer genetics; epigenetics; tumor heterogeneity; histone modification; next-generation sequencing (NGS); cancer transcriptomics; gene regulation; mouse model; chromatin remodeling; CHIP-Seq; ATAC-seq; mutation; amplification
(This special issue belongs to the Section Genetics and Genomics)
Breast Cancer: Molecular and Cellular Mechanism and Biomarkers submission deadline 30 Nov 2026 | Viewed by 396 | Submission Open
Keywords: breast cancer; biomarkers; molecular mechanisms; multidrug resistance; personalized medicine; molecular targeted therapy; gene expression
(This special issue belongs to the Section Cancer Biology)
Biological Foundations of Psychiatric Disorders
edited by Rammohan Shukla
submission deadline 30 Nov 2026 | Viewed by 265 | Submission Open
Keywords: psychiatric disorders; molecular mechanisms; animal models; therapeutic discovery; genetic associations; sex differences; protocols; methods; behavioral studies; stress-related phenotypes
(This special issue belongs to the Section Neuroscience)
Ecological Dynamics of Vector-Borne Pathogens: From Hosts to Vectors
edited by , and Hugo C. R. Vilhena
submission deadline 30 Nov 2026 | Viewed by 107 | Submission Open
Keywords: vector-borne pathogens; host– vector interactions; climate change; disease emergence
(This special issue belongs to the Section Microbiology)
Stem Cell Stress Responses: Mechanisms, Models, and Implications
edited by Taku Kaitsuka
submission deadline 30 Nov 2026 | Viewed by 103 | Submission Open
Keywords: stem cells; stress response; differentiation; heat stress; hypoxic stress; oxidative stress; mechanical stress; proteotoxic stress; membrane protein; stress-inducible transcription factor
(This special issue belongs to the Section Cell Biology)
Neurodegeneration: Pathways and Mechanisms submission deadline 30 Nov 2026 | Viewed by 77 | Submission Open
Keywords: inflammation; oxidative stress; apoptosis; exercise; diet; cellular pathways
(This special issue belongs to the Section Neuroscience)
New Perspectives of Immunity Against SARS-CoV-2 submission deadline 30 Nov 2026 | Viewed by 61 | Submission Open
Keywords: innate and adaptive immune responses; viral immune evasion; mucosal and systemic immunity; vaccine-induced protection; host– pathogen interactions; immunomodulation and antiviral strategies
(This special issue belongs to the Section Immunology)
Insect Habits, Habitats and Interactions
edited by
submission deadline 30 Nov 2026 | Viewed by 21 | Submission Open
Keywords: adaptation; Insecta; plant– insect interactions; life history; niche; coevolution; pollination; disease transmission; insect flight; metamorphosis; sociality
(This special issue belongs to the Section Ecology)
Machine Learning and AI Approaches for Genomic and Transcriptomic Insights in Health and Disease
edited by
submission deadline 30 Nov 2026 | Viewed by 20 | Submission Open
Keywords: AI applications in biology and medicine; deep learning approaches in multiomic data integration and analysis; DNA/protein language modeling; computational genomics; AI-driven disease modeling
(This special issue belongs to the Section Bioinformatics)
Redox-Active Phytochemicals as Modulators of ROS, RNS and RSS Signaling: From Molecular Mechanisms to Therapeutic Potential submission deadline 30 Nov 2026 | Viewed by 20 | Submission Open
Keywords: phytochemicals; bioactive compounds; medicinal plants; redox signaling; reactive oxygen species (ROS); reactive nitrogen species (RNS); reactive sulfur species (RSS); antioxidant mechanisms; redox modulation; hormesis; Nrf2 pathway; oxidative stress; natural products; nutraceuticals; health and disease
(This special issue belongs to the Section Plant Science)
Pathophysiology of Chronic Inflammatory Diseases
edited by Vincent Yuan
submission deadline 1 Dec 2026 | 4 articles | Viewed by 6724 | Submission Open
Keywords: chronic inflammation; autoimmune diseases; cytokines; inflammasome; metabolic dysfunction; oxidative stress; biomarkers; epigenetics; personalized medicine; therapeutic targets
(This special issue belongs to the Section Physiology)
Neural and Non-Neural Substrates of Behavior
edited by
submission deadline 1 Dec 2026 | Viewed by 25 | Submission Open
Keywords: neural substrate; non-neural substrate; neural network; learning and memory; information processing; behavior
(This special issue belongs to the Section Neuroscience)
Recent Advances in Understanding Systemic Lupus Erythematosus Pathogenesis
edited by Rohit Upadhyay
submission deadline 15 Dec 2026 | Viewed by 346 | Submission Open
Keywords: systemic lupus erythematosus (SLE); autoimmunity; immune dysregulation; B and T cell biology; interferon signaling; autoantibodies; epigenetics; biomarkers; therapeutic targets; systems immunology
(This special issue belongs to the Section Medical Biology)
Bacterial Secretion Systems: Mechanisms, Regulation, and Their Roles in Microbe–Microbe and Microbe–Host Interactions
edited by
submission deadline 15 Dec 2026 | Viewed by 93 | Submission Open
Keywords: secretion system; pathogenicity; quorum sensing; expression and regulation; transcriptomics; environmental adaptability; microbial interaction mechanism
(This special issue belongs to the Section Microbiology)
Biology of Liver Diseases submission deadline 20 Dec 2026 | 4 articles | Viewed by 13710 | Submission Open
Keywords: viral hepatitis; alcoholic hepatitis; non-alcoholic steatohepatitis; autoimmune hepatitis; primary biliary cholangitis; liver cirrhosis; liver cancer; portal hypertension
(This special issue belongs to the Section Medical Biology)
Impacts of Climate Change on Terrestrial Carbon Cycling and Biodiversity Across Spatial and Temporal Scales submission deadline 21 Dec 2026 | 4 articles | Viewed by 3281 | Submission Open
Keywords: climate change; terrestrial carbon cycling; biodiversity; spatial and temporal scales; ecosystem resilience; UN CBD; UN Decade on Ecosystem Restoration; responsible business; nature-based solutions; sustainable development
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Advances in Tropical and Subtropical Plant Ecology and Physiology
edited by Naysa Flávia Ferreira Do Nascimento and Edna Ursulino Alves
submission deadline 30 Dec 2026 | 5 articles | Viewed by 1941 | Submission Open
Keywords: tropical plants; plant ecology; plant physiology; environmental adaptations; phenotypic diversity; climate change; biodiversity conservation; sustainable management
(This special issue belongs to the Section Plant Science)
Neuroprotective Strategies in Preclinical Animal Models of Neurological Disorders
edited by Lucia Buccarello
submission deadline 30 Dec 2026 | Viewed by 30 | Submission Open
Keywords: neuroprotective strategies; intracellular signaling pathways; synaptic dysfunction; oxidative stress: neuronal/cell death; preclinical animal models; neurodegeneration; microglia– neuron interaction; neurotrophin signaling; natural compounds
(This special issue belongs to the Section Neuroscience)
Biology, Pathogenesis, and Genomics of Animal Viruses
edited by Andrea Elizabeth Verna
submission deadline 30 Dec 2026 | Viewed by 28 | Submission Open
Keywords: animal viruses; molecular virology; viral genomics; host– virus interactions; viral pathogenesis; innate immunity; comparative genomics; One Health; emerging viruses
(This special issue belongs to the Section Microbiology)
Advances and Perspectives in tRNA Biology
edited by
submission deadline 30 Dec 2026 | Viewed by 26 | Submission Open
Keywords: tRNA biology; tRNA modifications; sequencing; translational control; codon decoding; tRNA fragments; RNA structure; ribosome dynamics; RNA-based regulation; disease mechanisms
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Feature Papers in Immunology submission deadline 30 Dec 2026 | Viewed by 20 | Submission Open
Keywords: immune regulation and signaling networks; host– pathogen interactions; innate and adaptive immune responses; immunometabolism and metabolic control of immunity; tumor immunology and immune evasion; autoimmunity and inflammatory diseases; immune modulation and therapeutic targeting; microenvironmental regulation of immune function; molecular and cellular mechanisms of immunity; multi-omics and systems immunology approaches
(This special issue belongs to the Section Immunology)
Advances in Aquatic Ecological Disasters and Toxicology
edited by and
submission deadline 31 Dec 2026 | 8 articles | Viewed by 8512 | Submission Open
Keywords: aquatic ecological disasters; aquatic toxicology; aquatic ecosystem; algal blooms; pollutants
Biology, Ecology and Management of Aquatic Macrophytes and Algae—2nd Edition
edited by , and Shuang Zhao
submission deadline 31 Dec 2026 | 5 articles | Viewed by 5732 | Submission Open
Keywords: aquatic macrophytes and algae; ecological planning and management; harmful algal blooms and control; biological resources and environment; aquatic ecosystem stability; ecological restoration; biodiversity; plant physiology; biomarkers; symbiotic microorganisms
The Potential of Genetics and Plant Breeding in Crop Improvement submission deadline 31 Dec 2026 | 6 articles | Viewed by 5423 | Submission Open
Keywords: plants; plant signaling pathways; growth and development; genomics; transcriptomics; proteomics; metabolomics; gene transformation; molecular biology; biochemistry; molecular breeding; genome editing; CRISPR/Cas9; marker-assisted selection; genome-wide selection; crop improvement; genetic diversity; quality traits; yield; disease resistance; environmental stress; plant-microbe interactions; drought tolerance; salinity resistance; oxidative stress; phytohormone
(This special issue belongs to the Section Plant Science)
Sustainable Management of Aquatic Animal Health: Advances in Immunology, Pathogenesis, and Innovative Disease Control Strategies
edited by and
submission deadline 31 Dec 2026 | 2 articles | Viewed by 3536 | Submission Open
Keywords: aquatic animal health; immunology; pathogenesis; CRISPR-based innovations; sustainable aquaculture
(This special issue belongs to the Section Immunology)
Pathobiology of Cardiac Arrhythmias and Heart Failure Issues
edited by Mohit Hulsurkar
submission deadline 31 Dec 2026 | 1 articles | Viewed by 916 | Submission Open
Keywords: cardiac arrhythmias; atrial fibrillation; heart failure; ion channelopathy; cardiac fibrosis; cardiomyopathy
(This special issue belongs to the Section Physiology)
Advances in Biological Research into Shrimps, Crabs and Lobsters (2nd Edition)
edited by Lutz Auerswald
submission deadline 31 Dec 2026 | 3 articles | Viewed by 653 | Submission Open
Keywords: Crustacea; Decapoda; biology; fishery; aquaculture; ecology; bio-compounds; seafood; physiology; immunology; genetics
(This special issue belongs to the Section Zoology)
Aquatic Economic Animal Breeding and Healthy Farming (2nd Edition)
edited by Yude Wang and Shengwei Luo
submission deadline 31 Dec 2026 | 1 articles | Viewed by 639 | Submission Open
Keywords: rice– fish; fish; and aquaculture; hybridization and genetic breeding; nutrient additive and requirement; physiology and immune response; disease control; pathogenesis research; probiotic identification and function; transcriptomics; proteomics; metabonomics
(This special issue belongs to the Section Zoology)
Cellular Senescence in Development, Regeneration, Aging, and Cancer
edited by
submission deadline 31 Dec 2026 | Viewed by 557 | Submission Open
Keywords: cellular senescence; aging; cancer; obesity; metabolism; geroscience; age-related diseases; SASP; senolytics; biomarkers
Feature Papers on Toxicology
edited by
submission deadline 31 Dec 2026 | 2 articles | Viewed by 474 | Submission Open
Keywords: toxicology; cellular toxicity; organ toxicity; biomarkers; molecular mechanisms; in vitro models; in vivo models; risk assessment; environmental exposures; chemical toxicology
(This special issue belongs to the Section Toxicology)
Adaptation and Protection Mechanisms in Marine Ecosystem Under Climate Change
edited by and Ya-Fan Chan
submission deadline 31 Dec 2026 | Viewed by 437 | Submission Open
Keywords: global climate change; seawater acidification; marine ecosystem; marine biology; marine biogeochemistry TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in Zulu   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate Zulu to Simplified Chinese Never translate Zulu Never translate admin.mdpi.com
(This special issue belongs to the Section Ecology)
Metabolic and Stress Responses in Aquatic Animals (2nd Edition)
edited by , Laura Fernández-Alacid and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 367 | Submission Open
Keywords: stress; metabolism; animal welfare; aquaculture; cephalopods; fish; molluscs; crustaceans; aquatic animals; animal physiology
(This special issue belongs to the Section Zoology)
Vegetation Detection and Ecosystem Carbon Modeling submission deadline 31 Dec 2026 | Viewed by 315 | Submission Open
Keywords: vegetation detection; ecosystem carbon modeling  ; biomass estimation  ; carbon dynamics  ; forest and agro-ecosystem monitoring  ; remote sensing  ; allometric modeling  ; machine learning  ; UAV imagery; climate-change mitigation
(This special issue belongs to the Section Ecology)
Fungal Biodiversity and Ecology: Unraveling Ecological Roles, Interactions, and Environmental Adaptations
edited by Xin Qian, Junzhi Qiu and Yonglong Wang
submission deadline 31 Dec 2026 | Viewed by 268 | Submission Open
Keywords: fungal biodiversity; fungal ecology; ecosystem functioning; community assembly; fungal interactions; taxonomy and systematics; extreme environments; biogeography; fungal conservation; biotechnology applications
(This special issue belongs to the Section Ecology)
Plant Developmental Transition Under Changing Climate
edited by Zeeshan Nasim
submission deadline 31 Dec 2026 | Viewed by 215 | Submission Open
Keywords: plant development; reproductive transition; flowering; climate change; global warming TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Ecology)
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