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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Effect of Dietary Antioxidants in Chronic Disease Prevention

edited by

Baojun Xu

submission deadline 25 May 2025 | 9 articles | Viewed by 23817 | Submission Open

Keywords: dietary antioxidants; chronic diseases; molecular mechanisms; oxidative stress; reactive oxygen species; inflammation; signaling pathways

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Dietary Health: The Role of Functional Foods and Nutritional Supplements

edited by

Ivana Jukić

submission deadline 25 May 2025 | 4 articles | Viewed by 5220 | Submission Open

Keywords: functional food; diet; dietary supplements; nutrition; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Preventive and Therapeutic Effects of Fruit Antioxidants on Chronic Diseases

edited by

Chongde Sun

and

Yue Wang

submission deadline 30 May 2025 | 2 articles | Viewed by 4545 | Submission Open

Keywords: fruit antioxidants; chronic diseases; oxidative stress; inflammation; cardiovascular health; diabetes management; cancer prevention; neuroprotection; nutritional strategies

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Redox Biomarkers in Cancer

edited by Kevin D. Bunting

submission deadline 30 May 2025 | 1 articles | Viewed by 1741 | Submission Open

Keywords: hematopoiesis; leukemogenesis; redox signaling; JAK-STAT pathway; cancer biology; stem cell biology

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Effect of Nutritional Intervention and Diet on Oxidative Stress and Human Diseases

edited by

Josep A. Tur

, Cristina Bouzas and

Margalida Monserrat-Mesquida

submission deadline 30 May 2025 | 1 articles | Viewed by 983 | Submission Open

Keywords: nutrition; diet; oxidative stress; inflammation; human chronic diseases; supplements; cardiovascular diseases; diabetes; obesity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Diabetic Retinopathy

edited by Tatsuya Mimura

submission deadline 30 May 2025 | Viewed by 136 | Submission Open

Keywords: diabetic retinopaty; oxidative stress; antioxidants; inflammation; environmental factor

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants for Skin Health

edited by Rubia Casagrande

submission deadline 31 May 2025 | 17 articles | Viewed by 41458 | Submission Open

Keywords: skin inflammation; cytokine; skin oxidative stress; Nrf2; reduced glutathione; ultraviolet irradiation; drug delivery; flavonoid; terpenes; specialized pro-resolution lipid mediators

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Poultry Reproduction and Nutrition

edited by Caiqiao Zhang

submission deadline 31 May 2025 | 6 articles | Viewed by 19614 | Submission Open

Keywords: oxidative stress; antioxidants; poultry reproduction; poultry nutrition; molecular mechanisms; physiological homeostasis; ovarian development; ovarian aging; nutrition regulation; energy metabolism

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Phenolic Compounds in Foods, Plants and Related By-Products—2nd Edition

edited by

Giovanni Caprioli

submission deadline 31 May 2025 | 9 articles | Viewed by 17353 | Submission Open

Keywords: phenolic compounds; food and plants analyses; by-products chemical characterization; biological activities; valorization and recovery of by-products; food supplement; functional food; antioxidant activity; extraction methods; analytical methods

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Exploring Recent Advances in Plant Extracts: Understanding Antioxidant Mechanisms and Health Benefits

edited by Gianina Cristina Crişan and

Ana-Maria Vlase

submission deadline 31 May 2025 | 6 articles | Viewed by 15455 | Submission Open

Keywords: antioxidant activity; oxidative stress; molecular mechanisms; natural products; plant extracts; nutraceuticals; health outcomes; synergistic effects; chronic diseases; metabolic disorders; cancer prevention; bioaccessibility; metabolism; novel pharmaceutical formulations; modern extraction techniques; preclinical and clinical trials

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Valorization of the Antioxidant Power of Natural Compounds

edited by

and

submission deadline 31 May 2025 | 6 articles | Viewed by 14779 | Submission Open

Keywords: polyphenols; antioxidant activity; green extraction; green solvents; green chemistry; nanotechnology; natural and synthetic materials

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Redox Regulation in Animal Reproduction

edited by Zhongliang Jiang

submission deadline 31 May 2025 | 6 articles | Viewed by 12382 | Submission Open

Keywords: spermatogenesis; follicular atresia; oocyte maturation; granulosa cells; hormone regulation; autophagy; apoptosis; oxidative stress; signaling regulation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Redox Signaling in Cancer Progression and Therapy

edited by

Kui Wang

and

Yunlong Lei

submission deadline 31 May 2025 | 3 articles | Viewed by 6368 | Submission Open

Keywords: ROS; oxidative stress; redox signaling; cancer; antioxidants

Development and Validation of Methods for Analysis of Oxidative Stress in Humans and Animals—2nd Edition

edited by

José Joaquín Cerón

and

Camila Peres Rubio

submission deadline 31 May 2025 | 4 articles | Viewed by 5167 | Submission Open

Keywords: antioxidants; assays; health; oxidants; redox; validation; welfare

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Therapies in Cardiovascular, Cardiorenal and Metabolic Diseases

edited by Kaushik P. Patel, Hong Zheng and

Tapan Patel

submission deadline 31 May 2025 | 5 articles | Viewed by 3724 | Submission Open

Keywords: antioxidant therapies; oxidative stress; cardiovascular diseases; cardiorenal diseases; metabolic diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Recent Advances in Applications of Antioxidants in Livestock Health and Reproduction

edited by Weijun Pang

submission deadline 31 May 2025 | 2 articles | Viewed by 3388 | Submission Open

Keywords: antioxidants; livestock health; reproduction; production efficiency; disease-resistant ability; growth and development; latest progress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Role of Antioxidants in Enhancing Training Adaptation, Exercise Performance, and Post-exercise Recovery

edited by

Sihui Ma

and

Katsuhiko Suzuki

submission deadline 31 May 2025 | 1 articles | Viewed by 2635 | Submission Open

Keywords: exercise science; antioxidants; ROS; sports; exercise physiology

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Actions of Melatonin

edited by

Gaia Favero

submission deadline 31 May 2025 | 3 articles | Viewed by 2290 | Submission Open

Keywords: antioxidant effects; human health; melatonin; oxidative stress

Oxidative/Nitrosative Stress in Cardiovascular Diseases

edited by

Claudia Penna

and Saveria Femminò

submission deadline 31 May 2025 | 2 articles | Viewed by 2185 | Submission Open

Keywords: oxidative stress; cardiovascular disease; therapeutic approaches; biomarkers; exercise; aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Hormones and Oxidative Stress

edited by

Silvia Nistri

submission deadline 31 May 2025 | 1 articles | Viewed by 1947 | Submission Open

Keywords: reactive oxygen species; oxidative stress; hormones; antioxidants; melatonin; insulin; estrogen

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Trace Elements, Redox Balance, and Neurological Diseases

edited by

Yan-Zhong Chang

and Hong Jiang

submission deadline 31 May 2025 | 1 articles | Viewed by 1725 | Submission Open

Keywords: iron; copper; zinc; selenium; redox; Alzheimer's disease; Parkinson's disease; stroke; ageing; brain-targeted nanomedicines

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress Mechanisms and Parkinson's Disease Treatment

edited by

Juan Segura-Aguilar

submission deadline 31 May 2025 | 1 articles | Viewed by 865 | Submission Open

Keywords: Parkinson’ s disease; dopamine; dopamine oxidation; neuromelanin; dopaminergic neurons; antioxidants; neuroprotection; neurodegeneration; oxidative stress; protein degradation dysfunction; neuroinflammation; mitochondrial dysfunction; endoplasmic reticulum stress; alpha-synuclein oligomers; glutathione; glutathione transferase; DT-diaphorase; preclinical model for Parkinson's disease; VMAT2; dopamine transporter; tyrosine hydroxylase; dopamine-derived orto-quinones

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Targeting Oxidative Stress to Manage Pain

edited by

Cristiane Flora Villarreal

submission deadline 31 May 2025 | 1 articles | Viewed by 835 | Submission Open

Keywords: chronic pain; antioxidants; analgesics; nociceptive sensitization

Oxidative Stress and Immune Regulation in Respiratory Diseases

edited by María José Calzada

submission deadline 31 May 2025 | Viewed by 372 | Submission Open

Keywords: chronic respiratory diseases; oxidative stress; immune regulation; airway inflammation; mitochondrial dysfunction; pulmonary hypertension

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants from the Perspective of Environmental Physiology and Pathology

edited by

Gianfranco Santovito

submission deadline 31 May 2025 | Viewed by 175 | Submission Open

Keywords: antioxidants; environmental stress; pollutants; health; oxidative stress

Oxidative Stress in Cardiovascular Diseases (CVDs)

edited by

Roberto Palacios-Ramirez

and

Ernesto Martínez-Martínez

submission deadline 10 Jun 2025 | 5 articles | Viewed by 16403 | Submission Open

Keywords: ROS; oxidative stress; antioxidants; cardiovascular diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Exploring the Interplay of Antioxidant Activity and Phytochemical Composition in Plant Extracts and Bee Products

edited by

Lina Raudonė

, Mindaugas Liaudanskas and Sonata Trumbeckaite

submission deadline 10 Jun 2025 | 4 articles | Viewed by 6016 | Submission Open

Keywords: natural products; phenolic compounds; antioxidant activity; plant sources; bee products; health benefits; analytical methods; phytochemical composition

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants as Weapons to Maintain or Restore Oral Health

edited by

Célia Fortuna Rodrigues

and

José Carlos Andrade

submission deadline 10 Jun 2025 | 1 articles | Viewed by 1610 | Submission Open

Keywords: polyphenols; biofilms; oral mucositis; gingivitis; caries; AMR

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Homeostasis in Poultry/Animal Production

edited by

Peter F. Surai

submission deadline 15 Jun 2025 | 7 articles | Viewed by 16430 | Submission Open

Keywords: redox homeostasis; oxidative stress; antioxidants; transcription factors; immunity; inflammation; poultry; pigs; cattle

Antioxidants for the Oxidative Stabilisation of Food Lipids

edited by

Joaquin Velasco

submission deadline 15 Jun 2025 | 2 articles | Viewed by 3897 | Submission Open

Keywords: antioxidants; oxidative stabilisation; food lipids; oil– water interfaces; lipid oxidation

Mass Spectrometry in the Analysis of Antioxidants and Products of Redox Reactions

edited by

Rafał Frański

submission deadline 15 Jun 2025 | Viewed by 923 | Submission Open

Keywords: flavonoids; phenolic acids; tannins; lignans; glutathione; disulfide bond redox state; oxidoreductase; NADPH oxidase; cellular redox; food preservation; material stabilizers; electrodes; batteries; electrochemical cell

(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)

Plant Materials and Their Antioxidant Potential, 2nd Edition

edited by

Elisabeta Irina Geana

and

Ovidiu Tita

submission deadline 20 Jun 2025 | 10 articles | Viewed by 17576 | Submission Open

Keywords: fruits and vegetables; medicinal plants; agro-food industry; food ingredients; functional foods; nutraceuticals; food supplements; pharmaceutical products; antioxidant activity; oxidative stress; aging; anti-inflammatory activity; sustainable recovery; circular bioeconomy

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Applications of Antioxidant Nanoparticles, 2nd Edition

edited by

Rita Cortesi

and

Maddalena Sguizzato

submission deadline 20 Jun 2025 | 4 articles | Viewed by 9316 | Submission Open

Plant Antioxidants, Inflammation, and Chronic Disease

edited by

Hae-Jeung Lee

and

Jin Ah Cho

submission deadline 20 Jun 2025 | 7 articles | Viewed by 8878 | Submission Open

Keywords: plant antioxidants; free radicals; oxidative stress; polyphenol; carotenoids; vitamin C; vitamin E; selenium; inflammation; chronic disease; cardiovascular diseases; diabetes; cancer; neurodegenerative disorders; immune function

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Role of Nutrition and Exercise in the Prevention and Treatment of Oxidative Stress-Associated Diseases

edited by

Dejan Reljic

Yurdagül Zopf

and

Hans Joachim Herrmann

submission deadline 20 Jun 2025 | 4 articles | Viewed by 8420 | Submission Open

Keywords: nutrition; physical activity; exercise; oxidative stress; chronic diseases; cardiovascular disease; type 2 diabetes; cancer; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Translation of Antioxidant Therapies to the Clinical Arena of Ischemic Stroke

edited by María Castelló-Ruiz, Juan B. Salom and Irene Escudero-Martínez

submission deadline 20 Jun 2025 | 3 articles | Viewed by 6027 | Submission Open

Keywords: Ischemic stroke; endovascular treatment; reperfusion; oxidative stress; cerebroprotectants; antioxidant therapeutic approaches

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Systems in Plants

edited by

Francisco Espinosa Borreguero

, Ilda Jesús Casimiro Felicio and

Inmaculada Garrido Carballo

submission deadline 20 Jun 2025 | 1 articles | Viewed by 354 | Submission Open

Keywords: enzymatic antioxidants; non-enzymatic antioxidants; nitro-oxidative stress; reactive oxygen species; reactive nitrogen species; ROS and RNS signaling

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Role of Mitochondria and ROS in Health and Disease

edited by

Paola Venditti

Gaetana Napolitano

and

Gianluca Fasciolo

submission deadline 25 Jun 2025 | 6 articles | Viewed by 9734 | Submission Open

Keywords: ROS; mitochondria; antioxidant; oxidative stress; neurological diseases; metabolic diseases; retinal diseases; mitochondrial disfunctions; mitochondria endoplasmic reticulum communication; mitochondrial bioenergetics; ageing; physical activity

(This special issue belongs to the Section ROS, RNS and RSS)

Reactive Oxygen Species in Different Biological Processes—Second Edition

edited by

Fabiana Pizzolongo

and

Stefania Filosa

submission deadline 30 Jun 2025 | 7 articles | Viewed by 49242 | Submission Open

(This special issue belongs to the Section ROS, RNS and RSS)

The Use of Antioxidant-Rich Foods and Supplements in Disease Prevention

edited by

Abraham Wall Medrano

Escobar-Puentes Alberto A.

and

Gustavo Adolfo González-Águilar

submission deadline 30 Jun 2025 | 1 articles | Viewed by 6601 | Submission Open

Keywords: dietary antioxidants; bioactivity; metabolomics; human diet; xenobiotics; polyphenols; vitamins; health promotion

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Male Reproductive Health

edited by

Robert John Aitken

Joel R. Drevet

, Zamira Gibb and

Geoffry De Iuliis

submission deadline 30 Jun 2025 | 4 articles | Viewed by 4510 | Submission Open

Keywords: oxidative stress; antioxidant therapy; male reproductive health; male fertility; erectile dysfunction; prostatic disease; male ageing

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Age-Related Changes in Skeletal Muscle and Vascular Health

edited by

Thiago Silveira Álvares

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3800 | Submission Open

Keywords: phytochemicals; phenolic compounds; antioxidant supplementation; bioactivity; oxidative stress; reactive oxygen species; nitric oxide; endothelial function; microvascular reactivity; muscle oxygenation; muscle quality; fatigue resistance; sarcopenia; aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Antioxidants and Their Oxidized Derivatives in Processed Food

edited by Concetta Condurso and Maria Merlino

submission deadline 30 Jun 2025 | 1 articles | Viewed by 3692 | Submission Open

Keywords: natural antioxidants; oxidized derivatives; bioavailability/bioaccessibility; antioxidant activity; processed food; thermal treatment; non-thermal treatment; innovative processing technologies; mild processing technologies; active packaging; shelf-life; nutritional benefits; health benefits; sensory quality

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Multi-Target Profile of Antioxidant Compounds, Including Repurposing and Combination Strategies—2nd Edition

edited by

Roberta Rocca

submission deadline 30 Jun 2025 | 3 articles | Viewed by 3506 | Submission Open

Keywords: polypharmacology; multi-target ligands; rational drug; design repurposing; off-target effects; computational techniques

Antioxidant Activity of Polyphenolic Extracts

edited by

Dimitrios Stagos

submission deadline 30 Jun 2025 | 3 articles | Viewed by 3139 | Submission Open

Keywords: antioxidant activity; polyphenols; plant extracts; oxidative stress

Nitric Oxide (NO) and Hydrogen Sulfide (H₂S) in Biology, Illness, and Therapies—2nd Edition

edited by

Eizo Marutani

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2564 | Submission Open

Keywords: nitric oxide; hydrogen sulfide; persulfide/polysulfide; sulfur metabolism; redox reaction; interaction/crosstalk; antioxidants; disease; therapy; detection methods

(This special issue belongs to the Section ROS, RNS and RSS)

Recent Advances in Applications of Nanoantioxidants

edited by

Anna Calarco

and Raffaele Conte

submission deadline 30 Jun 2025 | 1 articles | Viewed by 2445 | Submission Open

Keywords: nanoantioxidants; nanoscale engineering; medicine; cosmetics; functional foods; material characterization

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidants and Food Supplements

edited by

Mariano Stornaiuolo

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2374 | Submission Open

Keywords: food supplements; natural bioactive compound; antioxidants; oxidative stress; cellular pathways; nutraceuticals; free radicals; health outcomes; disease prevention

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Carotenoids in Health and Disease

edited by Kazutoshi Shindo

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1065 | Submission Open

Keywords: antioxidant activities of carotenoids; analytical chemistry on carotenoids; reactive oxygen species (ROS) and disease; production of carotenoids

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Redox Biology and Genomic Integrity

edited by

Viktor Stolc

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1033 | Submission Open

Keywords: redox biology; reactive oxygen species (ROS); oxidative stress; oxidative DNA damage; genome stability; DNA repair; hypermutation; antioxidant defense mechanisms; mitochondrial dysfunction; Saccharomyces cerevisiae; cellular adaptation; epigenetics; telomeres

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