Significance of Antioxidant Mechanisms in Intestinal Inflammation—2nd Edition

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: 20 December 2025 | Viewed by 20

Special Issue Editors


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Guest Editor
Department of Pharmacology, Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain
Interests: antioxidant; immune response; inflammation; microbiota; polyphenols; prebiotics; probiotics
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Pharmacology, Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain
Interests: antioxidant; intestinal inflammation; microbiota; natural compounds; postbiotics; prebiotics; probiotics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In view of the great response to our previous Special Issue "Significance of Antioxidant Mechanisms in Intestinal Inflammation", we are excited to announce a new edition dedicated to this important and evolving topic.

Oxidative stress continues to play a pivotal role in the pathogenesis and progression of intestinal inflammation. In recent years, antioxidant therapy has emerged as a potential approach to mitigate inflammation and oxidative damage in the gut. In the context of intestinal inflammation, antioxidants such as vitamins C and E, selenium, and natural polyphenols like curcumin and resveratrol have shown promise in reducing inflammation by reducing oxidative damage to intestinal cells. Although numerous experimental and clinical studies have demonstrated that antioxidants could modulate key pathways involved in inflammation, such as NF-κB and MAPK signalling, leading to a reduced production of pro-inflammatory cytokines, many questions remain unanswered. A more comprehensive understanding of how reactive oxygen species are generated and regulated during intestinal inflammation—and how these processes interact with current and emerging therapies—will be essential in identifying novel therapeutic targets and strategies.

As Guest Editors, we invite you to contribute to this Special Issue focused on the role of oxidative stress in the initiation and progression of intestinal inflammation, as well as during therapeutic interventions.

Dr. Alba Rodríguez-Nogales
Dr. Maria Elena Rodriguez Cabezas
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • antioxidant therapy
  • antioxidants
  • intestinal inflammation
  • oxidative stress
  • polyphenol
  • reactive oxygen/nitrogen species
  • redox homeostasis

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This special issue is now open for submission.
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