Antioxidant Systems, Transcription Factors and Non-Coding RNAs
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "ROS, RNS and RSS".
Deadline for manuscript submissions: 15 September 2025 | Viewed by 664
Special Issue Editor
Interests: oxidative stress; cellular senescence; transcription factors; non-coding RNAs; chromatin remodeling factors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Antioxidant systems protect against perturbation of the intracellular redox status due to high levels of reactive oxygen/nitrogen species (ROS/RNS). Accordingly, dysfunction in these systems can trigger oxidative damage and foster diseases like neurodegeneration, senescence/aging, cancer, and different types of cardiac and kidney disorders. ROS/RNS-sensitive transcription factors closely associate with defense programs, since they can engage downstream enzymatic and non-enzymatic antioxidant pathways to restore redox balance. These defense processes are often dynamically interlinked with post-transcriptional regulatory mechanisms mediated by non-coding RNAs, mainly microRNAs, long-non-coding RNAs, and circular RNAs, also involved in epigenetic regulatory events. Therefore, the interplay between transcription factors and non-coding RNAs is found to be important within the antioxidant response, and ongoing research is focused on these redox regulators.
This Special Issue aims to collect original research articles, communications, and reviews defining novel non-coding RNA-mediated regulatory mechanisms that influence the activities of redox transcription factors and their importance in the antioxidant defense network. Exploring these characteristics may facilitate the development of novel non-coding RNA therapeutics, aimed at governing healthy living.
Dr. Raffaella Faraonio
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antioxidant systems
- oxidative stress
- transcription factors
- non-coding RNAs
- stress response
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