Combination Therapy of Antimicrobial
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "The Global Need for Effective Antibiotics".
Deadline for manuscript submissions: closed (16 June 2022) | Viewed by 24318
Special Issue Editor
Interests: antimicrobial pharmacotherapy; bacterial metabolism; secondary metabolism/metabolic engineering; molecular biology; recombinant genetics; enzymology; pharmacokinetics/pharmacodynamics; mechanisms of antimicrobial resistance; antimicrobial tolerance
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Effective antimicrobial therapy has permitted entire fields of medicine to develop, including organ transplantation and highly intensive chemotherapy. However, treatment with a single antibiotic is not always sufficient in terms of antimicrobial potency or prevention of resistance development. Unlike treatments for HIV infection or tuberculosis, use of combination therapy remains controversial for many bacterial infections. This Special Issue seeks manuscript submissions that further our understanding of when combination therapy is appropriate, why combination therapy can be beneficial, and how best to administer antibiotic combinations. We propose topic prompts below, but manuscripts addressing other aspects of combination therapy are welcome:
- Appropriateness of empiric combination therapy in endovascular Staphylococcus aureus infection;
- Combination therapy as a resistance mitigation strategy;
- Genetic or physiological mechanisms of antimicrobial synergy;
- Clinical trial design to assess antimicrobial combinations;
- Antimicrobial combinations as salvage therapies;
- Appropriate endpoints to evaluate clinical effectiveness of combination therapy;
- Appropriate use criteria for initiation of combination therapy;
- Combination therapy in the context of resistance to one of the agents;
- Maintaining appropriate combination therapy across transitions of care.
Dr. Andrew David Berti
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Combination Therapy
- Synergy
- Antimicrobial Resistance