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  • Review
  • Open Access
164 Citations
54,338 Views
55 Pages

Salmonellosis: An Overview of Epidemiology, Pathogenesis, and Innovative Approaches to Mitigate the Antimicrobial Resistant Infections

  • Bibek Lamichhane,
  • Asmaa M. M. Mawad,
  • Mohamed Saleh,
  • William G. Kelley,
  • Patrick J. Harrington,
  • Cayenne W. Lovestad,
  • Jessica Amezcua,
  • Mohamed M. Sarhan,
  • Mohamed E. El Zowalaty and
  • Hazem Ramadan
  • + 2 authors

Salmonella is a major foodborne pathogen and a leading cause of gastroenteritis in humans and animals. Salmonella is highly pathogenic and encompasses more than 2600 characterized serovars. The transmission of Salmonella to humans occurs through the...

  • Review
  • Open Access
42 Citations
45,154 Views
37 Pages

19 December 2022

Bacterial central nervous system (CNS) infections are serious and carry significant morbidity and mortality. They encompass many syndromes, the most common being meningitis, which may occur spontaneously or as a consequence of neurosurgical procedure...

  • Review
  • Open Access
138 Citations
38,360 Views
30 Pages

3 November 2023

Multidrug-resistant Gram-negative bacterial infections are exponentially increasing, posing one of the most urgent global healthcare and economic threats. Due to the lack of new therapies, the World Health Organization classified these bacterial spec...

  • Review
  • Open Access
56 Citations
35,247 Views
19 Pages

Evidence-Based Treatment of Pseudomonas aeruginosa Infections: A Critical Reappraisal

  • Arta Karruli,
  • Christian Catalini,
  • Chiara D’Amore,
  • Francesco Foglia,
  • Fabio Mari,
  • Arjan Harxhi,
  • Massimiliano Galdiero and
  • Emanuele Durante-Mangoni

16 February 2023

Multidrug-resistant (MDR)/extensively drug-resistant (XDR) Pseudomonas aeruginosa is emerging as a major threat related to adverse patient outcomes. The goal of this review is to describe evidence-based empiric and targeted treatment regimens that ca...

  • Article
  • Open Access
3 Citations
35,098 Views
21 Pages

Background: The emergence of multidrug-resistant (MDR) Staphylococcus aureus presents a critical global health challenge due to treatment failures and high mortality rates. Faced with this growing threat, new antimicrobials with original modes of act...

  • Review
  • Open Access
30 Citations
34,801 Views
13 Pages

Topical Antibiotic Treatment in Dermatology

  • Matthew Dallo,
  • Kavina Patel and
  • Adelaide A. Hebert

Many indications in dermatology can be effectively managed with topical antibiotics, including acne vulgaris, wound infections, secondarily infected dermatitis, and impetigo. Dermatologists must be familiar with the wide spectrum of topical antibioti...

  • Review
  • Open Access
34 Citations
32,768 Views
37 Pages

Staphylococcus aureus: A Review of the Pathogenesis and Virulence Mechanisms

  • Rahima Touaitia,
  • Assia Mairi,
  • Nasir Adam Ibrahim,
  • Nosiba S. Basher,
  • Takfarinas Idres and
  • Abdelaziz Touati

Staphylococcus aureus is a formidable human pathogen responsible for infections ranging from superficial skin lesions to life-threatening systemic diseases. This review synthesizes current knowledge on its pathogenesis, emphasizing colonization dynam...

  • Review
  • Open Access
231 Citations
32,717 Views
23 Pages

Klebsiella pneumoniae is a Gram-negative opportunistic pathogen responsible for a variety of community and hospital infections. Infections caused by carbapenem-resistant K. pneumoniae (CRKP) constitute a major threat for public health and are strongl...

  • Review
  • Open Access
162 Citations
32,230 Views
27 Pages

Clinical Impact of Staphylococcus aureus Skin and Soft Tissue Infections

  • Matthew S. Linz,
  • Arun Mattappallil,
  • Diana Finkel and
  • Dane Parker

The pathogenic bacterium Staphylococcus aureus is the most common pathogen isolated in skin-and-soft-tissue infections (SSTIs) in the United States. Most S. aureus SSTIs are caused by the epidemic clone USA300 in the USA. These infections can be...

  • Review
  • Open Access
23 Citations
30,979 Views
24 Pages

Neonatal Sepsis: A Comprehensive Review

  • Charikleia Kariniotaki,
  • Christina Thomou,
  • Despoina Gkentzi,
  • Eleftherios Panteris,
  • Gabriel Dimitriou and
  • Eleftheria Hatzidaki

Neonatal sepsis remains a significant cause of neonatal morbidity and mortality globally. At present, no clear consensus definition for sepsis in neonates exists, even though a positive blood culture is considered as the gold standard for definitive...

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Antibiotics - ISSN 2079-6382