2026 September - 18 articles
Background/Objectives: Social media has become a major source of health information worldwide; however, how users appraise the credibility of online health information and verify its reliability may be associated with medication-related decision-maki...
Background: Medication errors (MEs) are an important cause of preventable harm but remain insufficiently quantified in emergency care. This study assessed the frequency, characteristics, and clinical impact of MEs among adverse drug reaction (ADR)&nd...
Background: Sodium-glucose cotransporter-2 (SGLT2) inhibitors have been shown to reduce the rate of chronic kidney disease (CKD) progression and provide cardioprotective benefits beyond glycemic control. However, evidence regarding their effects on k...
Background: Anticoagulant treatment is central to the prevention and management of thromboembolic cardiovascular disease, and contemporary practice has increasingly shifted toward direct oral anticoagulants. Objectives: To quantify ambulatory anticoa...
Background/Objectives: Primary non-adherence occurs when a prescribed medicine is never collected, preventing treatment from the beginning. Despite non-adherence being a widespread problem, most evidence comes from Western European and North American...
Background/Objectives: Patient access to cannabinoid-based therapies in Brazil has expanded with the availability of regulated Cannabis-derived products (CDPs). This study explored CDP prescribing practices among Brazilian physicians. Methods: Betwee...
Background/Objectives: Antipsychotic-induced hyperprolactinemia may adversely affect skeletal health through suppression of the hypothalamic–pituitary–gonadal axis; however, the independent association between circulating prolactin and bo...
Background/Objectives: Comparator selection can change disproportionality findings when multidrug therapies are represented by report-level listings rather than verified treatment histories. We evaluated a proxy-comparator framework for cardiometabol...
Background/Objectives: Tenofovir disoproxil fumarate (TDF)-containing regimens remain the cornerstone of first-line antiretroviral therapy (ART) in many low- and middle-income countries. However, concerns regarding treatment failure and antiretrovira...
Background/Objectives: Croatia is among the European countries with moderately high antibiotic consumption and correspondingly elevated antimicrobial resistance (AMR) rates. National-level surveillance, however, masks substantial county-level heterog...
Background/Objectives: Methylphenidate is widely used for attention-deficit/hyperactivity disorder and is available in immediate-release (IR) and extended-release (XR) formulations. Long-term reported private-sector dispensing data from Costa Rica re...
Background: In Italy, seasonal flu vaccination was recommended for all children aged 6 months to 6 years, all adults aged ≥60 years and specific at-risk groups. Influenza vac-cine effectiveness (IVE) varies from season to season. It can be related...
Background: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) and GLP-1/glucose-dependent insulinotropic polypeptide (GIP) dual agonists have revolutionized the treatment of type 2 diabetes and obesity. The rapid growth in public interest, off-lab...
Background and Objective: Helicobacter pylori infection remains a major cause of chronic gastritis, dyspepsia, and peptic ulcer disease worldwide. Increasing antibiotic resistance, particularly to clarithromycin, has reduced the effectiveness of stan...
Background: The purpose of this preliminary study was to evaluate the use of the Zipf–Mandelbrot (ZM) law to mathematically model the percentage occurrence of adverse drug reactions (ADRs), as a function of rank, reported to the United States F...
Background: Proton pump inhibitors (PPIs) are widely used for the treatment of gastrointestinal (GI) disorders. Omeprazole is one of the most commonly prescribed PPIs in Thailand. However, it is frequently overprescribed in hospital settings, increas...
Background/Objectives: We described adverse event reporting patterns for insulin glargine marketed as 100 units/mL (Lantus), 300 units/mL (Toujeo), and 100 units/mL biosimilars (Basaglar/Semglee). Methods: We analyzed Food and Drug Administration Adv...
Background/Objectives: Medication adherence is a critical determinant of therapeutic outcomes in type 2 diabetes mellitus (T2DM); however, its relationship with glycemic control remains inconsistent, particularly in real-world and socially vulnerable...
