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Chemistry, Volume 5, Issue 4

December 2023 - 39 articles

Cover Story: The bio-based solvent dihydrolevoglucosenone (Cyrene) is a green and sustainable alternative to petroleum-based dipolar aprotic solvents. Cyrene can be prepared from cellulose in a simple two-step process and can be produced in a variety of yields. Cyrene is compatible with a large number of reactions in the chemical industry and can be applied in organic chemistry, biocatalysis, materials chemistry, graphene and lignin processing, etc. It is also green, non-mutagenic and non-toxic, which makes it very promising for applications. View this paper
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Articles (39)

  • Article
  • Open Access
2 Citations
2,921 Views
13 Pages

12 December 2023

The first total synthesis of the proposed structure of unprecedented indolyl derivative bearing 1,2-propanediol moiety is described. Isomerization of 3-alkoxyindolines through indolenium intermediates was the key step in the total synthesis. 1H, 13C-...

  • Article
  • Open Access
2 Citations
2,653 Views
16 Pages

12 December 2023

Brown algae possess a diverse array of acidic polysaccharides, including fucoidan. The present research intends to investigate the extraction and characterization of algal polysaccharides to explore their antiviral activity. A light brown sulfated po...

  • Review
  • Open Access
7 Citations
4,216 Views
43 Pages

Recent Advances in C–H Functionalization of Pyrenes

  • Srinivasarao Arulananda Babu,
  • Arup Dalal and
  • Subhankar Bodak

11 December 2023

In recent years, transition metal-catalyzed C–H activation and site-selective functionalization have been considered to be valuable synthetic tactics to functionalize organic compounds containing multiple C–H bonds. Pyrene is one of the p...

  • Review
  • Open Access
1 Citations
2,394 Views
13 Pages

Chiral Hydroxamic Acid Ligands in the Asymmetric Synthesis of Natural Products

  • Tushar Janardan Pawar,
  • Karla Irazu Ventura-Hernández,
  • Fernando Rafael Ramos-Morales and
  • José Luis Olivares-Romero

1 December 2023

Chiral hydroxamic acid (HA) and bis-hydroxamic acid (BHA) ligands have made significant contributions to the field of asymmetric synthesis, particularly in the synthesis of natural products. These ligands possess unique molecular structures that allo...

  • Article
  • Open Access
2,339 Views
18 Pages

1 December 2023

The iron-promoted 1,5-substitution reaction of endocyclic oxiranes with MeMgBr yields exocyclic 2,4,5-trienols with high diastereomeric ratios of up to 100:0. However, for the method’s success, the oxirane ring must have a trans-configuration....

  • Editorial
  • Open Access
2,984 Views
5 Pages

27 November 2023

It is my pleasure to welcome you to Chemistry (ISSN: 2624-8549), an open access peer-reviewed journal that publishes both primary reports and reviews highlighting important advances in fundamental areas of chemistry and/or illustrating the central ro...

  • Article
  • Open Access
2 Citations
3,663 Views
20 Pages

Bioactive Pyrrolo[2,1-f][1,2,4]triazines: Synthesis, Molecular Docking, In Vitro Cytotoxicity Assay and Antiviral Studies

  • Nataliya N. Mochulskaya,
  • Svetlana K. Kotovskaya,
  • Ilya I. Butorin,
  • Mikhail V. Varaksin,
  • Valery N. Charushin,
  • Vladimir L. Rusinov,
  • Yana L. Esaulkova,
  • Alexander V. Slita,
  • Polina A. Ilyina and
  • Vladimir V. Zarubaev

21 November 2023

A series of 2,4-disubstituted pyrrolo[2,1-f][1,2,4]triazines containing both aryl and thienyl substituents were synthesized by exploiting the 1,3-cycloaddition reaction of N(1)-ethyl-1,2,4-triazinium tetrafluoroborates with dimethyl acetylenedicarbox...

  • Essay
  • Open Access
3 Citations
6,474 Views
27 Pages

21 November 2023

The dn number or configuration is a very useful parameter in transition metal chemistry because it conveys information about the expected properties of a d-block metal complex, including its shape, magnetism, thermodynamic stability, kinetic lability...

  • Article
  • Open Access
9 Citations
2,381 Views
17 Pages

New Zwitterionic Imidazolones with Enhanced Water Solubility and Bioavailability: Synthesis, Anticancer Activity, and Molecular Docking

  • Saber Abu-Jabal,
  • Ahmad Ghareeb,
  • Derar Smadi,
  • Othman Hamed,
  • Mohyeddin Assali,
  • Avni Berisha,
  • Nael Abutaha,
  • Waseem Mansour,
  • Ameed Omairah and
  • Alaa Janem
  • + 1 author

21 November 2023

Finding an effective anticancer drug to combat cancer cell resistance remains a challenge. Herein, we synthesized a new series of imidazolone derivatives 4a–4i and assessed their anticancer activities against liver cancer cells (Hep3B), Hela ce...

  • Article
  • Open Access
1 Citations
1,964 Views
15 Pages

Polymerization Behavior and Rheological Properties of a Surfactant-Modified Reactive Hydrophobic Monomer

  • Xin Wen,
  • Lei Wang,
  • Xiaojuan Lai,
  • Guiru Liu,
  • Wenwen Yang,
  • Jinhao Gao,
  • Yameng Liu and
  • Wenyu Cui

14 November 2023

The structures and properties of hydrophobic association polymers can be controlled using micelles. In this work, we synthesize a reactive hydrophobic surfactant monomer, KS-3, from oleic acid, N,N-dimethylpropylenediamine, and allyl chloride. A stro...

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Chemistry - ISSN 2624-8549Creative Common CC BY license