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Proceedings, 2026, INOVATEC 2025

The 6th International Congress on Health Innovation—INOVATEC 2025

Hybrid | 21–23 November 2025

Volume Editor:

Andreanne Gomes Vasconcelos, University of Brasília (UnB), Brasília, Brazil
Amílcar Sabino Damazo, University of Brasília (UnB), Brasília, Brazil
José Roberto de Souza de Almeida Leite, University of Brasília (UnB), Brasília, Brazil

Number of Papers: 154
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Cover Story (view full-size image): The 6th International Congress on Health Innovation (INOVATEC 2025) was held from 21 to 23 November 2025 in Brasília, Brazil, with the theme “Disruptive innovations for inclusive, [...] Read more.
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2 pages, 149 KB  
Editorial
Statement of Peer Review
by Andreanne Vasconcelos, Amílcar Damazo and José Roberto Leite
Proceedings 2026, 137(1), 153; https://doi.org/10.3390/proceedings2026137153 - 28 Apr 2026
Viewed by 265
Abstract
In submitting conference proceedings to Proceedings, the Volume Editors of the proceedings would like to certify to the publisher that all papers published in this volume have been subjected to peer review by the designated expert referees and were administered by the [...] Read more.
In submitting conference proceedings to Proceedings, the Volume Editors of the proceedings would like to certify to the publisher that all papers published in this volume have been subjected to peer review by the designated expert referees and were administered by the Volume Editors, strictly following the policies announced on the conference website (https://inovatecdf [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
5 pages, 562 KB  
Editorial
Preface of the 6th International Congress on Health Innovation—INOVATEC 2025
by Andreanne Vasconcelos, Amílcar Damazo and José Roberto Leite
Proceedings 2026, 137(1), 154; https://doi.org/10.3390/proceedings2026137154 - 28 Apr 2026
Viewed by 375
Abstract
The 6th International Congress on Health Innovation—INOVATEC 2025—was held from 21 to 23 November 2025 in Brasília, Federal District, Brazil, with the theme “Disruptive innovations for inclusive, borderless health” (inovatecdf [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
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Research

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2 pages, 119 KB  
Abstract
Correlation Between Mu Rhythm on Electroencephalogram and Visual Behaviors in Children with ASD: An Integrative Literature Review
by Pedro H. F. Pinto, Humberto M. A. Montenegro and Carlos N. Aucélio
Proceedings 2026, 137(1), 1; https://doi.org/10.3390/proceedings2026137001 - 14 Feb 2026
Viewed by 360
Abstract
Introduction: The present study investigates the correlation between Mu rhythm, a marker of neuronal activity present in the electroencephalogram (EEG), and visual behaviors in children with autism spectrum disorder (ASD) [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 108 KB  
Abstract
Prions as Neglected Infectious Agents: A Review on Atypical Transmission Routes, Environmental Resilience, and Epidemiological Implications for Global Health
by Caio C. Carvalho and Maria C. E. S. Barros
Proceedings 2026, 137(1), 2; https://doi.org/10.3390/proceedings2026137002 - 14 Feb 2026
Viewed by 516
Abstract
Introduction: Prions are unique protein-based infectious agents responsible for the class of diseases known as Transmissible Spongiform Encephalopathies (TSEs), which are universally fatal [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 137 KB  
Abstract
Advances in Assistive Technology: A Systematic Review of 3D-Printed Hand Prostheses
by Ulisses B. Viana Filho, Lucas E. da S. Barbosa, Maria J. da S. Santos, Thayná M. F. de Oliveira, Marcelo de A. Buriti and Amanda G. de A. Vieira
Proceedings 2026, 137(1), 3; https://doi.org/10.3390/proceedings2026137003 - 17 Feb 2026
Viewed by 468
Abstract
Introduction: The application of 3D printing in the development of hand prostheses offers customized, low-cost solutions with high functional potential for the field of assistive technology [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 162 KB  
Abstract
Applications of Spectroscopy in Veterinary Clinical Analysis—Literary Review
by Thiago R. Silva, Lavinia M. Barbosa, Rômulo D. A. Andrade, Eduarda S. Fabri, Maria H. R. Marques and Heitor A. B. da Silva
Proceedings 2026, 137(1), 4; https://doi.org/10.3390/proceedings2026137004 - 17 Feb 2026
Viewed by 564
Abstract
Introduction: UV–Vis spectrophotometry is a central technique in veterinary diagnostics, enabling quantification of biomolecules such as glucose, proteins, and creatinine, as well as minerals and pharmaceuticals [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 155 KB  
Abstract
3D Spheroid Models for Drug Testing and Histological Processing with Coconut Oil: An Experimental Study of In Vitro Analysis
by Vinícius Q. F. Silva, Juliano C. T. T. Almeida, Luan B. V. Costa, Maria G. Silva, Andreanne G. Vasconcelos and José R. S. A. Leite
Proceedings 2026, 137(1), 5; https://doi.org/10.3390/proceedings2026137005 - 18 Feb 2026
Viewed by 384
Abstract
Introduction: Three-dimensional (3D) cell cultures are laboratory models composed of cells that grow in three dimensions and interact with each other and the extracellular matrix, which results in proliferation, differentiation, morphology, and functionality conditions similar to those in living tissues and makes [...] Read more.
Introduction: Three-dimensional (3D) cell cultures are laboratory models composed of cells that grow in three dimensions and interact with each other and the extracellular matrix, which results in proliferation, differentiation, morphology, and functionality conditions similar to those in living tissues and makes these platforms adequate for drug testing [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 152 KB  
Abstract
Impacts of Emerging Technologies on Hospital Buildings in Brazil
by João Paulo L. Pompermaier, Lizandra G. L. Vergara and Patrícia B. Cavalcanti
Proceedings 2026, 137(1), 6; https://doi.org/10.3390/proceedings2026137006 - 18 Feb 2026
Viewed by 373
Abstract
Introduction: Healthcare 4 [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 136 KB  
Abstract
Impact of Nanosensors on Monitoring and Diagnosis of Cardiovascular Diseases: A Systematic Review
by Lucas Emanuel da Silva Barbosa, Ulisses Bezerra Viana Filho, Thayná Mylena Ferreira de Oliveira, Maria Júlia da Silva Santos and Marcelo de Almeida Buriti
Proceedings 2026, 137(1), 7; https://doi.org/10.3390/proceedings2026137007 - 19 Feb 2026
Viewed by 295
Abstract
Introduction: Nanosensors are emerging technologies in the diagnosis and monitoring of cardiovascular diseases, standing out for their high sensitivity and clinical potential [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 137 KB  
Abstract
Functional Radioligand Assays for Investigating the Interaction Between NeuroVAL Peptide and Dopaminergic Receptors: Standardization and Validation
by Jéssica W. Ferreira, Gabriel A. A. Campos, Letícia G. Veras and Márcia Renata Mortari
Proceedings 2026, 137(1), 8; https://doi.org/10.3390/proceedings2026137008 - 19 Feb 2026
Viewed by 347
Abstract
Introduction: Binding assays are essential in the screening of substances for new drugs, allowing the evaluation of the interaction of compounds with relevant molecular targets [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 133 KB  
Abstract
Annatto-Based Nanoemulsions as Promising Agents for Wound Healing
by Jhenyfer B. Santos, Gabriella O. Silva, Graziella A. Joanitti and Marcella L. B. Carneiro
Proceedings 2026, 137(1), 9; https://doi.org/10.3390/proceedings2026137009 - 19 Feb 2026
Viewed by 286
Abstract
Introduction: Annatto biocompounds (BiOx) exhibit antioxidant, anti-inflammatory, and antimicrobial properties, which can be enhanced through nanostructuring to promote wound healing [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 133 KB  
Abstract
Development of Melatonin-Loaded Chitosan Nanoparticles for Enhanced Topical Drug Delivery
by Giovanna A. F. Barcelos, Jayanaraian F. M. Andrade, Maria E. M. Nóbrega, Marcílio Cunha-Filho, Guilherme M. Gelfuso and Tais Gratieri
Proceedings 2026, 137(1), 10; https://doi.org/10.3390/proceedings2026137010 - 19 Feb 2026
Viewed by 455
Abstract
Introduction: Melatonin (MEL) is a natural hormone with anti-aging, anti-wrinkle, and anti-inflammatory properties, making it promising for topical cosmetics [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 160 KB  
Abstract
Evaluation of the Antimicrobial Activity of Kombucha Cellulose Discs Hydrated with Lactobacillus gasseri Supernatant
by Carla Azevedo Bilac, Mickelle Oliveira Evangelista Monteiro, Isabelle Rijo Oliveira, Rebeca Dias dos Santos, Letícia Fernandes Silva Rodrigues, Daniel Oliveira Freire, Nathália Lorena Rocha Freire, Izabel Cristina Rodrigues da Silva, Livia Cristina Lira de Sá Barreto and Daniela Castilho Orsi
Proceedings 2026, 137(1), 11; https://doi.org/10.3390/proceedings2026137011 - 19 Feb 2026
Viewed by 468
Abstract
Introduction: Bacterial cellulose (BC) is a natural biopolymer produced by bacteria and has been widely studied for biomedical applications [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 147 KB  
Abstract
Formulation and Characterization of Annatto Oil and Curcumin Nanoemulsions with Wound Healing and Antimicrobial Potential
by Gabriella O. Silva, Patrícia A. Oliveira, Mosar C. Rodrigues, Paulo H. Oliveira, Sebastião W. Silva, Graziella A. Joanitti and Marcella L. B. Carneiro
Proceedings 2026, 137(1), 12; https://doi.org/10.3390/proceedings2026137012 - 20 Feb 2026
Viewed by 263
Abstract
Introduction Nanoemulsions (NEs) are promising systems to improve the solubility and bioavailability of poorly water-soluble compounds [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 122 KB  
Abstract
Epidemiological Profile of Patients with Malignant Neoplasia of the Glans Penis in the Federal District and Goiás (2019–2025)
by Isadora M. França, Gabriela P. Silveira, Isabelly Silva, Josuel B. Albuquerque and Paulo H. R. Martins
Proceedings 2026, 137(1), 13; https://doi.org/10.3390/proceedings2026137013 - 20 Feb 2026
Viewed by 270
Abstract
Introduction: Malignant neoplasia of the glans penis (MNG), represented by squamous cell carcinoma, is a major health problem, especially in developing countries, where prevalence is higher and diagnoses tend to occur at advanced stages [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 135 KB  
Abstract
Engineering of Microbial Expression Systems for the In Vitro Production of Anticancer Peptides
by Giovana A. Vasconcelos, Pedro E. B. Guedes, Thais M. M. Ferreira, Victor A. Cunha, André R. C. Junior, Octavio L. Franco and Karen O. Osiro
Proceedings 2026, 137(1), 14; https://doi.org/10.3390/proceedings2026137014 - 20 Feb 2026
Viewed by 285
Abstract
Introduction: Cancer causes nearly 10 million deaths worldwide each year, with approximately 704,000 new cases in Brazil [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 121 KB  
Abstract
Anatomical and Clinical Integration in the Diagnosis of Piriformis Syndrome: A Systematic Review and Cadaveric Findings
by Samuel C. da Silva, Ana C. F. Leite, Isaac D. S. V. Prado, Lavinia H. A. Torres, Luigi Gallo, Mateus G. C. Soares and Carlos N. Aucélio
Proceedings 2026, 137(1), 15; https://doi.org/10.3390/proceedings2026137015 - 21 Feb 2026
Viewed by 434
Abstract
Introduction: Piriformis syndrome (PS) is a compressive neuropathy caused by sciatic nerve irritation due to its relationship with the piriformis muscle [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 139 KB  
Abstract
Effects of Methylphenidate Use Among Undiagnosed College Students with ADHD: An Integrative Literature Review
by Ana Clara L. S. Rodrigues, Cintia C. Mascarenhas, Emilly A. C. Silvério, Janaina C. Mascarenhas, Kathleen L. O. Dutra, Letycia C. Silva, Marcela N. Cavassani, Rafaella B. Nunes and Sophia A. Vilela
Proceedings 2026, 137(1), 16; https://doi.org/10.3390/proceedings2026137016 - 20 Feb 2026
Viewed by 479
Abstract
Introduction: Methylphenidate (Ritalina) is a central nervous system stimulant widely used in the treatment of attention deficit hyperactivity disorder (ADHD) [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 176 KB  
Abstract
CAR-NK Cells: A Promising Emerging Approach in Cancer Immunotherapy—A Review
by Eduarda S. Fabri, Maria H. R. Marques, Heitor A. B. Da Silva, Thiago R. Silva, Lavinia M. Barbosa and Rômulo D. Albuquerque
Proceedings 2026, 137(1), 17; https://doi.org/10.3390/proceedings2026137017 - 23 Feb 2026
Viewed by 924
Abstract
Chimeric Antigen Receptor-modified Natural Killer (CAR-NK) cells have emerged as a promising strategy in cancer immunotherapy by combining the intrinsic cytotoxic activity of NK cells with antigen-specific targeting through genetic engineering [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 151 KB  
Abstract
Blue Light-Enhanced Nanoformulations: Curcumin and Annatto Oil as Photodynamic Agents in Inflammation Modulation
by Lucas M. Syllos, Natalia L. Chaves, Luísa C. Coelho, Gabriella O. Silva, Mosar C. Rodrigues, Graziella A. Joanitti, Anamélia L. Bocca and Marcella L. B. Carneiro
Proceedings 2026, 137(1), 18; https://doi.org/10.3390/proceedings2026137018 - 23 Feb 2026
Viewed by 277
Abstract
Introduction: Chronic inflammation and oxidative stress sustain diabetic-wound pathophysiology [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 145 KB  
Abstract
Genetic Influence of APOB XbaI Polymorphism on Eating Behaviors and Hematological Profiles in Depressed Adults: A Pilot Clinical Insight
by Antonio A. F. Soares, Dante M. T. Teixeira, Alexandre S. R. Pereira, Alexandre P. Batista, Bruna F. M. Alencar, Calliandra M. S. Silva, Marcela M. G. Paes, Matheus G. Castro, Sophia T. T. Alves and Izabel C. R. Silva
Proceedings 2026, 137(1), 19; https://doi.org/10.3390/proceedings2026137019 - 23 Feb 2026
Viewed by 270
Abstract
Introduction: Lipid metabolism disturbances have been linked to depression pathophysiology, with apolipoprotein B (APOB)—a key component of LDL particles—emerging as a relevant biomarker [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 137 KB  
Abstract
The Impact of Vaping and Nicotine on the Cardiovascular System: A Literature Review
by Larissa C. Guilhardi, Ananda S. Martins, Gabriela de J. S. Santos, Lucas F. Rodrigues, Polyana Y. do N. Dias, Emanuele C. Soares, Isabele G. de Olivera, Luís G. D. S. Albuquerque, Anna L. A. de Lima and Ligia C. A. Cardoso-Duarte
Proceedings 2026, 137(1), 20; https://doi.org/10.3390/proceedings2026137020 - 24 Feb 2026
Viewed by 640
Abstract
Introduction: Electronic cigarette use has been associated with adverse cardiovascular outcomes, including reduced oxygenation, elevated blood pressure, arrhythmias, and cardiorespiratory arrest [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 147 KB  
Abstract
A Comparative Descriptive Field Study on Physical Activity Practice and Adolescents’ BMI
by Thayná M. F. de Oliveira, Ulisses B. Viana Filho, Maria J. da S. Santos, Lucas E. da S. Barbosa and Marcelo de A. Buriti
Proceedings 2026, 137(1), 21; https://doi.org/10.3390/proceedings2026137021 - 24 Feb 2026
Viewed by 229
Abstract
Introduction: Physical Activity (PA) is essential for adolescent health, providing both physical and social benefits [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 154 KB  
Abstract
Histological Analysis of the Skin of Pithecopus spp. (Anura) and Functional Characterization of the Tryptophillin PaT-2 as an Antioxidant Peptide
by Flávia Geordana Damasceno Araújo, Henrique Loback Lopes de Araújo, Maria da Gloria da Silva, Eder Alves Barbosa, Andreanne Gomes Vasconcelos, Amílcar Sabino Damazo, Fernanda Leonel Silva, Daniel Carneiro Moreira and José Roberto de Souza de Almeida Leite
Proceedings 2026, 137(1), 22; https://doi.org/10.3390/proceedings2026137022 - 20 Feb 2026
Viewed by 247
Abstract
Introduction: Amphibians of the family Phyllomedusidae are characterized by complex cutaneous secretions with ecological and pharmacological relevance [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 142 KB  
Abstract
A Deep Brain Stimulation (DBS) for the Treatment of Refractory Depression: A Review of the Literature
by Maria F. O. Melo, Heitor C. Souza, Raíssa P. Naves, Victor I. Maciel, Isabele C. Mortari, Letícia G. L. Morais, Isabela M. Pereira, Amanda S. N. Oliveira, Ana J. S. Guerra and Helen D. S. C. Souza
Proceedings 2026, 137(1), 23; https://doi.org/10.3390/proceedings2026137023 - 20 Feb 2026
Viewed by 352
Abstract
Introduction: Depression is a chronic and multifactorial psychiatric illness that causes symptoms such as profound sadness, discouragement, loss of interest in activities, changes in sleep and appetite, and negative thoughts [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 149 KB  
Abstract
Impacts of Digital Technologies on the Cognitive Performance of Older Adults: A Systematic Literature Review
by Alicy Costa Cruvinel, Raíssa Pimentel Naves, Nicole Vieira Cruvinel, Ana Júlia Souza Guerra, Rafaela Teles Cruvinel, Maria Fernanda Oliveira Melo, Lucas Costa Cruvinel, Amanda Marques Lima, Letícia Geloysse Louredo Morais and Helen Danyane Soares Caetano Souza
Proceedings 2026, 137(1), 24; https://doi.org/10.3390/proceedings2026137024 - 24 Feb 2026
Viewed by 471
Abstract
Introduction: Population aging has intensified, bringing a higher prevalence of cognitive decline, related not only to the natural aging process but also to conditions such as mild cognitive impairment and dementias, including Alzheimer’s disease [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 165 KB  
Abstract
Antibacterial and Antioxidant Activity of Basil (Ocimum basilicum), Lemongrass (Elionurus muticus), and Pitanga (Eugenia uniflora) Essential Oils
by Rebeca D. dos Santos, Julia F. do Carmo, Daniele M. Silva, Anita M. Meireles, Eduarda R. Mendes, Carla A. Bilac, Letícia F. S. Rodrigues, Daniel O. Freire, Izabel C. R. da Silva and Daniela C. Orsi
Proceedings 2026, 137(1), 25; https://doi.org/10.3390/proceedings2026137025 - 24 Feb 2026
Viewed by 231
Abstract
Introduction: Essential oils (EO), present in leaves, flowers, stems, and roots, are rich in terpenes and phenolic compounds, conferring antimicrobial and antioxidant activities [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 121 KB  
Abstract
Health Education as a Social Technology in Tackling Geohelminthiases Experience with School-Aged Children
by Priscila S. da Costa, Natalia C. Aquino, Isabella C. A. Bessas and Neudson J. Martinho
Proceedings 2026, 137(1), 26; https://doi.org/10.3390/proceedings2026137026 - 25 Feb 2026
Viewed by 236
Abstract
Introduction: Geohelminthiases, classified as neglected tropical diseases, remain a persistent public health challenge, particularly in regions marked by social inequalities, inadequate sanitation, and substandard housing [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 142 KB  
Abstract
Comparative Analysis of Genomic DNA (gDNA) and Complementary DNA (cDNA) for the Identification of GATA1 Variants by Sanger Sequencing
by Maria Clara V. Berto, Isis M. Q. Magalhães, Marina C. Ribeiro, Bruna C. Guido, Agenor C. M. S. Júnior and Ricardo Camargo
Proceedings 2026, 137(1), 27; https://doi.org/10.3390/proceedings2026137027 - 25 Feb 2026
Viewed by 452
Abstract
Introduction: Variants in GATA1 gene represent an early and critical event in Transient Abnormal Myelopoiesis (TAM) and in the progression to Myeloid Leukemia associated with Down syndrome (ML-DS) [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 134 KB  
Abstract
Testosterone and Cervicovaginal Health in Transgender Men: An Integrative Review of Clinical Repercussions and the SUS
by João V. A. Sabate, Luanna R. Araujo, Lara K. P. G. Silva and Sussana S. T. Barbosa
Proceedings 2026, 137(1), 28; https://doi.org/10.3390/proceedings2026137028 - 25 Feb 2026
Viewed by 337
Abstract
Introduction: This study aimed to analyze scientific data on hormonal modulation with testosterone, its effects on cervicovaginal health in transgender men, and the role of the Unified Health System (SUS) in providing care to these individuals [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 129 KB  
Abstract
EGFRvIII-Targeted CAR-T Cell Therapy: A Systematic Review of Emerging Treatment Strategies for Glioblastoma
by Ana C. F. Leite, Luigi Gallo, Lavinia H. A. Torres, Mateus G. C. Soares, Samuel C. Silva, Isaac D. S. V. Prado and Carlos N. Aucélio
Proceedings 2026, 137(1), 29; https://doi.org/10.3390/proceedings2026137029 - 25 Feb 2026
Cited by 1 | Viewed by 1124
Abstract
Glioblastoma (GBM) is the most aggressive primary brain tumor, characterized by marked molecular heterogeneity and resistance to standard therapeutic approaches [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 124 KB  
Abstract
Electroencephalographic Findings as Treatment Markers in Children with Subdural Effusion by Meningitis by Haemophilus influenzae 
by Matheus S. Oliveira and Carlos N. Aucelio
Proceedings 2026, 137(1), 30; https://doi.org/10.3390/proceedings2026137030 - 25 Feb 2026
Viewed by 240
Abstract
The electroencephalogram (EEG) plays an important role in the clinical follow-up of children affected by subdural effusion secondary to Haemophilus influenzae meningitis, contributing to the evaluation of brain function and to the monitoring of response to treatment [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
121 KB  
Abstract
Cognitive and Emotional Effects of Music Through Neural Entrainment and Neuroplasticity: A Systematic Review
by Samuel C. da Silva, Ana C. F. Leite, Isaac D. S. V. Prado, Lavinia H. A. Torres, Luigi Gallo, Mateus G. C. Soares and Carlos N. Aucélio
Proceedings 2026, 137(1), 31; https://doi.org/10.3390/proceedings2026137131 - 20 Feb 2026
Viewed by 627
Abstract
Introduction: Music has accompanied humanity since the earliest civilizations, exerting social, esthetic, and neuromodulatory impacts [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 125 KB  
Abstract
Critical Gaps in Stroke Care: A Call for Urgent Reform in Laboratory Protocols and Diagnostic Access in Brazil
by Matheus G. Castro, Juliana M. A. Seixas, Antonio A. F. Soares, Alexandre P. Batista, Calliandra M. S. Silva, Cristina L. B. Furia and Izabel C. R. Silva
Proceedings 2026, 137(1), 32; https://doi.org/10.3390/proceedings2026137032 - 25 Feb 2026
Viewed by 204
Abstract
Introduction: Stroke remains a leading cause of morbidity and mortality in Brazil, requiring rapid and effective responses from the initial point of care [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 163 KB  
Abstract
Disk-Diffusion of Citrus aurantium dulcis, Rosmarinus officinalis, and Melaleuca alternifolia Essential Oils Against Bacteria and Yeasts
by Anita M. Meireles, Rebeca D. dos Santos, Sophia T. T. Alves, Stephanie de A. Mendonça, Julia F. do Carmo, Eduarda R. Mendes, Carla A. Bilac, Letícia F. S. Rodrigues, Izabel C. R. da Silva and Daniela C. Orsi
Proceedings 2026, 137(1), 33; https://doi.org/10.3390/proceedings2026137033 - 25 Feb 2026
Viewed by 287
Abstract
Introduction: Essential oils (EOs) are volatile compounds widely recognized for their antimicrobial properties [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 128 KB  
Abstract
The Therapeutic Potential of Snake Venom Toxins for the Treatment of Central Nervous System Tumors: A Review
by Luigi Gallo, Ana C. F. Leite, Isaac D. S. V. Prado, Lavínia H. A. Torres, Mateus G. C. Soares, Samuel C. Silva and Carlos N. Aucélio
Proceedings 2026, 137(1), 34; https://doi.org/10.3390/proceedings2026137034 - 25 Feb 2026
Viewed by 353
Abstract
Introduction: In the current treatment of central nervous system (CNS) tumors, natural bioactive compounds, especially snake venom toxins, stand out as promising therapeutic candidates for selectively modulating critical molecular targets in tumor progression [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 139 KB  
Abstract
The Relevance of the Biomedical Professional in Brazil’s National Immunization Program: A Descriptive Study
by Luanna R. Araujo, Thayssa N. F. Victer, Heloísa F. B. Souza and Glenda M. Mota
Proceedings 2026, 137(1), 35; https://doi.org/10.3390/proceedings2026137035 - 25 Feb 2026
Viewed by 234
Abstract
Introduction: The Unified Health System (SUS), established in 1988, ensures universality, comprehensiveness, and equity in healthcare [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 120 KB  
Abstract
Educational Practices in Hygiene and Sanitation as a Sustainable Strategy for the Prevention of Geohelminthiases: A Literature Review
by Priscila Sales Da Costa, Natalia De Carvalho Aquino, Isabele Silva Barbosa, Lorrayny Kristhal Schneiker Martins Bispo and Neudson Johnson Martinho
Proceedings 2026, 137(1), 36; https://doi.org/10.3390/proceedings2026137036 - 25 Feb 2026
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Abstract
Introduction: Geohelminthiases are parasitic infections transmitted through helminth eggs present in soil, water, and food [...] Full article
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2 pages, 144 KB  
Abstract
Non-Invasive Technologies for Anemia Screening in Remote Settings: A Literature Review
by Mailane A. Barreto, Ana E. V. Leal, Ângela V. Ribeiro, Daniel S. Santos, Gabrielle M. Alves, Gabrielly S. B. Rodrigues, Pedro A. Melo and Fernando V. C. Pucci
Proceedings 2026, 137(1), 37; https://doi.org/10.3390/proceedings2026137037 - 25 Feb 2026
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Abstract
Introduction: Anemia is a hematological condition characterized by reduced hemoglobin levels in the blood, impairing oxygen transport to tissues [...] Full article
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2 pages, 149 KB  
Abstract
Biochemical and Hematological Modulation by Smart Biomaterial-Based Therapies in Diabetic Wounds
by Gildemar J. B. Crispim, Gabriella O. Silva, Paulo H. Oliveira, Lara S. Almeida, Mosar C. Rodrigues, Graziella A. Joanitti and Marcella L. B. Carneiro
Proceedings 2026, 137(1), 38; https://doi.org/10.3390/proceedings2026137038 - 25 Feb 2026
Viewed by 239
Abstract
Introduction: Diabetes Mellitus (DM) impairs wound healing due to persistent hyperglycemia, promoting chronic inflammation and increasing infection risk [...] Full article
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2 pages, 140 KB  
Abstract
Potential Cytotoxic Effect of the Drug Interaction Between 5-FU and Carcinogens: Histopathological Evidence in an In Vivo Murine Model
by José Carlos E. Queiroz, Bruno S. Sá, Ester Alves Belarmino, Estéfani Alves Belarmino, Ana Gabriela P. Meneses, Pedro Paulo R. C. Melo, Maria G. da Silva, Amílcar S. Damazo, Ana Lúcia C. Sarmento and Andreanne G. Vasconcelos
Proceedings 2026, 137(1), 39; https://doi.org/10.3390/proceedings2026137039 - 25 Feb 2026
Viewed by 358
Abstract
Introduction: 5-fluorouracil (5-FU) is the standard chemotherapeutic agent for treating squamous cell carcinoma (SCC) [...] Full article
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2 pages, 121 KB  
Abstract
Phenolic Content and Antioxidant Activity of Softgel Capsules Containing Liquid Propolis Extract from Different Brands
by Yan M. S. Ribeiro, Karolina O. Gomes, Lívia C. S. Barreto, Izabel C. R. Silva and Daniela C. Orsi
Proceedings 2026, 137(1), 40; https://doi.org/10.3390/proceedings2026137040 - 25 Feb 2026
Viewed by 256
Abstract
Introduction: Dietary supplements can provide nutrients, bioactive substances, enzymes, or probiotics as a complement to diet [...] Full article
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2 pages, 155 KB  
Abstract
Phenotypic and Genotypic Antibiotic Resistance in Escherichia coli from Artisanal Minas Frescal Cheese in the Federal District, Brazil
by Letícia F. S. Rodrigues, Carla A. Bilac, Daniel O. Freire, Rebeca D. Santos, Andrea S. S. Moraes, Yan M. S. Ribeiro, Thálisson D. D. Cardoso, Bruno A. Prado, Daniela C. Orsi and Izabel C. R. Silva
Proceedings 2026, 137(1), 41; https://doi.org/10.3390/proceedings2026137041 - 25 Feb 2026
Viewed by 245
Abstract
Introduction: Artisanal Minas Frescal cheese, often produced under suboptimal hygienic/sanitary conditions, may harbor potentially pathogenic and antibiotic-resistant microorganisms [...] Full article
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2 pages, 120 KB  
Abstract
Development of a New Molecular Approach for Detecting Genetic Variants Predisposing to Thiopurine Toxicity in Pediatric ALL
by Cecília V. Lima and Agenor C. M. S. Júnior
Proceedings 2026, 137(1), 42; https://doi.org/10.3390/proceedings2026137042 - 25 Feb 2026
Viewed by 252
Abstract
Introduction: Thiopurine-associated toxicity in pediatric acute lymphoblastic leukemia (ALL) is related to polymorphisms in the TPMT and NUDT15 genes [...] Full article
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2 pages, 149 KB  
Abstract
Quality of Commercial and Manipulated Food Supplements Containing Ora-Pro-Nóbis Using an In Vitro Microbiological Approach
by Karolina O. Gomes, João P. G. S. Barros, Marta O. Araújo, Calliandra M. de Souza Silva, Daniel O. Freire, Yan M. S. Ribeiro, Priscila B. F. Arquelau, Izabel C. R. Silva, Lívia C. L. S. Barreto and Daniela C. Orsi
Proceedings 2026, 137(1), 43; https://doi.org/10.3390/proceedings2026137043 - 25 Feb 2026
Viewed by 299
Abstract
Introduction: Traditionally, the leaves and fruits of ora-pro-nóbis (OPN) are used to relieve inflammation, osteoporosis, iron deficiency anemia, dermatitis, and gastrointestinal disorders [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 158 KB  
Abstract
Quantification of Flavonoids and Computational Evaluation of Major Compounds of Chrysobalanus icaco L. Against Trypanosoma cruzi
by Mariana Fochesato, Ytallo C. Sousa, Ygor V. F. Pinheiro and Leiz M. C. Véras
Proceedings 2026, 137(1), 44; https://doi.org/10.3390/proceedings2026137044 - 25 Feb 2026
Viewed by 233
Abstract
Introduction: Chrysobalanus icaco L., popularly known as guajiru, is a medicinal plant
belonging to the family Chrysobalanaceae [...] Full article
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2 pages, 180 KB  
Abstract
Antimicrobial Activity of Vaccinium spp. (Blueberry) Leaf Extracts Against Candida albicans, Pseudomonas aeruginosa, and Staphylococcus aureus 
by Nathália Lorena Rocha Freire, Nicole C. B. Rêgo, Priscila B. F. Arquelau, Rebeca Dia dos Santos, Carla A. Bilac, Daniel O. Freire, Izabel C. R. Silva, Daniela C. Orsi and Eliana F. Gris
Proceedings 2026, 137(1), 45; https://doi.org/10.3390/proceedings2026137045 - 26 Feb 2026
Viewed by 399
Abstract
Introduction: The rise in antimicrobial resistance represents a global public health challenge, reinforcing the search for naturally occurring bioactive compounds with antimicrobial potential [...] Full article
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2 pages, 133 KB  
Abstract
Clinical Applicability of Physical Exercise in Alzheimer’s Disease and Mild Cognitive Impairment: A Secondary Analysis of Systematic Reviews
by Raphael L. Olegário, Elton F. F. S. Vieira, Júlia B. Hecksher, Lizandra R. Andrade, Marina L. S. Costa, Estêvão A. C. Waterloo-Filho, Kristine L. Alarcão and Cláudia Goulart
Proceedings 2026, 137(1), 46; https://doi.org/10.3390/proceedings2026137046 - 26 Feb 2026
Viewed by 320
Abstract
Introduction: Alzheimer’s disease (AD) and mild cognitive impairment (MCI) are major causes of cognitive decline, often accompanied by sleep disturbances and amyloid-β (Aβ) deposition [...] Full article
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2 pages, 142 KB  
Abstract
Determination of the Antibacterial Activity of Eucalyptus, Lavender, and Citronella Essential Oils Against Gram-Negative Microorganisms
by Eduarda R. Mendes, Rebeca D. dos Santos, Sophia T. T. Alves, Daniele M. Silva, Anita M. Meireles, Julia F. do Carmo, Carla A. Bilac, Letícia F. S. Rodrigues, Izabel C. R. da Silva and Daniela C. Orsi
Proceedings 2026, 137(1), 47; https://doi.org/10.3390/proceedings2026137047 - 26 Feb 2026
Viewed by 274
Abstract
Introduction: Gram-negative bacteria present a major therapeutic challenge due to their phospholipid barrier, which restricts drug penetration [...] Full article
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2 pages, 127 KB  
Abstract
Two Complementary Methods for the Measurement of Immunogenic Lipopeptides Critical Micelle Concentration
by Jésica A. Rodríguez, Silvia A. Camperi, Paolo Di Gianvincenzo and Sergio E. Moya
Proceedings 2026, 137(1), 48; https://doi.org/10.3390/proceedings2026137048 - 26 Feb 2026
Viewed by 288
Abstract
Introduction: Immunogenic lipopeptides are promising immunogens since their amphiphilic nature allows them to assemble into micelles, improving solubility, stability, and circulation half-life [...] Full article
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2 pages, 171 KB  
Abstract
Serum Levels of IL-10 and IL-1β in Elderly Individuals: Associations with Clinical and Demographic Factors
by Renata de Souza Freitas, Calliandra Maria de Souza Silva, Silvana Schwerz Funghetto, Rosângela Vieira de Andrade and Izabel Cristina Rodrigues da Silva
Proceedings 2026, 137(1), 49; https://doi.org/10.3390/proceedings2026137049 - 26 Feb 2026
Viewed by 407
Abstract
Introduction: Chronic low-grade inflammation is a hallmark of aging and is associated with various clinical conditions in older adults [...] Full article
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2 pages, 131 KB  
Abstract
Three-Dimensional Printing of Bone Structures: Evaluation of Heat Resistance in Anatomical Models for Replacement in Elderly Victims of Fractures
by Fabricio W. B. Martins, Cassiana M. Melo and Linconl A. O. Benito
Proceedings 2026, 137(1), 50; https://doi.org/10.3390/proceedings2026137050 - 26 Feb 2026
Viewed by 243
Abstract
Introduction: Three-dimensional printing in healthcare is emerging as a promising alternative for personalized therapies, enabling the development of prosthetics and anatomical models capable of assisting in clinical and surgical treatments [...] Full article
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2 pages, 121 KB  
Abstract
Histochemical Evaluation of Skin Lesions from Cutaneous Leishmaniasis Patients: Comparison of Processing with Xylene or Coconut Oil
by Cleia Abrantes da Silva, Jessica Luana Sousa da Costa, Maria Gloria da Silva and Amilcar Sabino Damazo
Proceedings 2026, 137(1), 51; https://doi.org/10.3390/proceedings2026137051 - 26 Feb 2026
Viewed by 231
Abstract
Introduction: Cutaneous leishmaniasis (CL) is a notifiable disease, and histopathological analysis constitutes one of the main diagnostic methods [...] Full article
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2 pages, 113 KB  
Abstract
Pathophysiological Mechanisms of EEG Alterations in Children with Subdural Effusion Due to Meningitis
by Matheus S. Oliveira and Carlos N. Aucelio
Proceedings 2026, 137(1), 52; https://doi.org/10.3390/proceedings2026137052 - 27 Feb 2026
Viewed by 243
Abstract
Introduction: Understanding the pathophysiological mechanisms underlying electroencephalographic alterations of subdural effusion as a complication of bacterial meningitis is essential for electro clinical correlation and optimization of patient management [...] Full article
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2 pages, 147 KB  
Abstract
Antimicrobial Potential and Synergistic Effect of Oregano Essential Oil (Origanum vulgare L.)
by Clara A. P. Rezende, Letícia F. S. Rodrigues, Carla A. Bilac, Daniel O. Freire, Rebeca D. Santos, Andrea S. S. Moraes, Thálisson D. D. Cardoso, Bruno A. Prado, Daniela C. Orsi and Izabel C. R. Silva
Proceedings 2026, 137(1), 53; https://doi.org/10.3390/proceedings2026137053 - 27 Feb 2026
Viewed by 888
Abstract
Introduction: Oregano (Origanum vulgare L [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
1 pages, 123 KB  
Abstract
A Review of Traumatic Brain Injury Evaluation in Sports
by Igor G. M. Quirido, Eduarda R. Martins, Mariana Y. Rodrigues, Cauã F. Martins and Selma A. S. Kückelhaus
Proceedings 2026, 137(1), 54; https://doi.org/10.3390/proceedings2026137054 - 27 Feb 2026
Viewed by 223
Abstract
Introduction: Traumatic brain injury (TBI), characterized by changes in brain function due to external forces, is an important challenge [...] Full article
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2 pages, 123 KB  
Abstract
Silver Nanoparticles and Their Antimicrobial Activity on Multidrug-Resistant Bacteria (AgNPs): A Literature Review
by Maria H. R. Marques, Eduarda S. Fabri, Heitor A. B. Da Silva, Thiago R. Silva, Lavinia M. Barbosa and Romulo D. A. Andrade
Proceedings 2026, 137(1), 55; https://doi.org/10.3390/proceedings2026137055 - 27 Feb 2026
Viewed by 719
Abstract
Conventional antibiotics have become increasingly compromised due to the constant growth of bacterial resistance, requiring new therapeutic strategies [...] Full article
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2 pages, 168 KB  
Abstract
Antimicrobial Resistance: Evidence on the Impact of Inappropriate Antibiotic Use—A Literature Review
by Anaclara A. Silva, Helena Costa, Maria Eduarda L. Reis, Sofia R. A. Assunção, Maria Gabriela F. Prado and Eduardo O. Pires
Proceedings 2026, 137(1), 56; https://doi.org/10.3390/proceedings2026137056 - 24 Feb 2026
Viewed by 496
Abstract
Introduction: Antimicrobial Resistance (AMR) is a major 21st-century global concern, given its projected rise in mortality and significant public health impacts [...] Full article
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2 pages, 125 KB  
Abstract
Association Between CYP2C19*2 Polymorphism and Clinical–Psychosocial Features in Patients with Major Depressive Disorder
by Larissa S. S. Bonasser, Calliandra M. de Souza Silva, Caroline F. Fratelli, Alexandre S. R. Pereira, Daniel O. Freire, Elias L. B. Cavalcante, Guilherme O. Rodrigues, Joanilson C. M. dos Santos, Jr., Livia C. L. de S. Barreto and Izabel C. R. da Silva
Proceedings 2026, 137(1), 57; https://doi.org/10.3390/proceedings2026137057 - 27 Feb 2026
Viewed by 235
Abstract
Introduction: The CYP2C19*2 allele is associated with reduced enzymatic activity and elevated scores in the personality trait “harm avoidance,” reflecting increased anticipatory worry and social shyness [...] Full article
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2 pages, 124 KB  
Abstract
Trivalent Peptide Design for Bevacizumab Salt-Induced Affinity Precipitation
by Joaquin A. Eloy, Gabriela R. Barredo-Vacchelli, Jésica A. Rodríguez, Barbara Richichi, Marco Marradi and Silvia A. Camperi
Proceedings 2026, 137(1), 58; https://doi.org/10.3390/proceedings2026137058 - 27 Feb 2026
Viewed by 373
Abstract
Introduction: Bevacizumab, applied in cancer treatment, binds vascular endothelial growth factor (VEGF) inhibiting blood vessels growth, avoiding tumours expansion [...] Full article
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2 pages, 131 KB  
Abstract
In Vitro Evaluation of Topical Follicular Delivery of Minoxidil and Latanoprost Co-Entrapped in Lipid Nanocarriers
by Camila O. Cardoso, Paula M. Oliveira, Mateus T. Silva, Marcílio Cunha-Filho, Taís Gratieri, Yogeshvar N. Kalia and Guilherme M. Gelfuso
Proceedings 2026, 137(1), 59; https://doi.org/10.3390/proceedings2026137059 - 27 Feb 2026
Viewed by 434
Abstract
Introduction: A major challenge in treating androgenic alopecia topically is delivering high drug levels in hair follicles while minimizing systemic absorption [...] Full article
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2 pages, 177 KB  
Abstract
Impacts of the COVID-19 Pandemic on Childhood Vaccination Coverage in Brazil: A Literature Review
by Anaclara A. Silva, Eduardo O. Pires, Helena Costa, Maria E. L. Reis, Maria G. F. Prado and Sofia R. A. Assunção
Proceedings 2026, 137(1), 60; https://doi.org/10.3390/proceedings2026137060 - 27 Feb 2026
Viewed by 396
Abstract
Introduction: The COVID-19 pandemic deepened a pre-existing decline in childhood vaccination coverage (VC) in Brazil, exposing children to diseases that had been eradicated [...] Full article
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2 pages, 164 KB  
Abstract
Development and Characterization of an Ex Vivo Human Skin Model for Melanoma Studies
by Maria V. Souto-Silva, Jankerle Boeloni, Eliza Duarte, Mayra Mendes, Carolina Souto, Stefhani Barcelos, Florêncio F. C. Neto, Guilherme M. Gelfuso, Felipe Saldanha-Araujo and Juliana L. Carvalho
Proceedings 2026, 137(1), 61; https://doi.org/10.3390/proceedings2026137061 - 28 Feb 2026
Viewed by 445
Abstract
Introduction: The development of ex vivo skin tumor models represents a relevant alternative to animal use, allowing the investigation of melanoma progression under physiological conditions closer to human skin [...] Full article
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2 pages, 125 KB  
Abstract
CYP2C19*17 Variant and Thyroid Function: A Genetic Link Between Metabolism, Cancer, and Endocrine Disruption
by Isabelle G. T. Mendonça, Leticia M. M. Lima, Calliandra Maria de Souza Silva, Marcos B. Mendonça, Daniel B. P. Filho, Rafael M. Morais, Larissa S. S. Bonasser, Ligia C. A. Cardoso-Duarte, Cristina L. B. Furia and Izabel C. R. Silva
Proceedings 2026, 137(1), 62; https://doi.org/10.3390/proceedings2026137062 - 28 Feb 2026
Viewed by 346
Abstract
Introduction: Cytochrome P450 (CYP) enzymes are essential for metabolizing drugs, hormones, and environmental compounds [...] Full article
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2 pages, 150 KB  
Abstract
Beyond Mood: Clinical Implications of DRD3 Ser9Gly Polymorphism in Eating Behavior and Biochemical Markers
by Bruna R. Gontijo, Yago R. Gontijo, Calliandra M. S. Silva, Julia M. Reis, Marcela M. G. Paes, Maurício L. Santos, Nádia C. Assunção, Rafaela O. Lopes, Caroline F. Fratelli and Izabel C. R. Silva
Proceedings 2026, 137(1), 63; https://doi.org/10.3390/proceedings2026137063 - 2 Mar 2026
Viewed by 500
Abstract
Introduction: Dopaminergic signaling, particularly via the dopamine receptor D3 (DRD3), is implicated in reward processing, mood regulation, and eating behavior [...] Full article
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2 pages, 150 KB  
Abstract
PCSK9 and Thyroid Tumor Dynamics: Exploring the Metabolic–Oncogenic Interface in PTC Patients
by Micaela A. Soares, Dante M. T. Teixeira, Bruna R. Gontijo, Calliandra M. S. Silva, Rafael M. Morais, Ligia C. A. Cardoso-Duarte, Jamila R. Oliveira, Cristina L. B. Furia and Izabel C. R. da Silva
Proceedings 2026, 137(1), 64; https://doi.org/10.3390/proceedings2026137064 - 2 Mar 2026
Viewed by 335
Abstract
Introduction: PCSK9 encodes a protein that regulates cholesterol homeostasis by promoting degradation of the low-density lipoprotein receptor (LDLR), thereby increasing plasma LDL-cholesterol levels and influencing cardiovascular risk [...] Full article
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2 pages, 160 KB  
Abstract
Applications of Artificial Intelligence in the Diagnosis of Acute Promyelocytic Leukemia: A Bibliographic Review
by Ângela V. Ribeiro, Gabrielle M. Alves, Gabrielly S. B. Rodrigues, Carlos D. C. M. Silva, Mailane A. Barreto, Daniel S. Santos, Ana E. V. Leal and Marcus V. C. M. Silva
Proceedings 2026, 137(1), 65; https://doi.org/10.3390/proceedings2026137065 - 2 Mar 2026
Viewed by 359
Abstract
Introduction: The use of Artificial Intelligence (AI) in healthcare has transformed professional practice, offering efficient results, optimizing processes, and expediting diagnostic evaluations [...] Full article
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2 pages, 123 KB  
Abstract
Visual Evoked Potentials in the Detection and Monitoring of Optic Neuritis in Multiple Sclerosis
by Enzo K. M. Rodrigues, Luiz F. V. Carvalho, Renato P. Cúrcio, Thiago C. Oliveira and Carlos N. Aucélio
Proceedings 2026, 137(1), 66; https://doi.org/10.3390/proceedings2026137066 - 2 Mar 2026
Viewed by 657
Abstract
Introduction: Visual Evoked Potential (VEP) detects failures in nerve conduction along visual pathways [...] Full article
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2 pages, 134 KB  
Abstract
Validation of a Chromatographic Method for Simultaneous Quantification of Imiquimod and Terbinafine in Porcine Skin
by Mikaella C. Sousa, Marianne A. P. C. Nogueira, Marcílio Cunha-Filho, Taís Gratieri, Larissa F. Matos and Guilherme M. Gelfuso
Proceedings 2026, 137(1), 67; https://doi.org/10.3390/proceedings2026137067 - 2 Mar 2026
Viewed by 242
Abstract
Introduction: Chromoblastomycosis is a chronic and neglected fungal infection of the skin and subcutaneous tissue, requiring long-term treatment and presenting therapeutic challenges [...] Full article
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2 pages, 137 KB  
Abstract
Genetic Editing with CRISPR in Cellular Models of Hematological Diseases: A Review
by Heitor A. B. da Silva, Eduarda S. Fabri, Maria H. R. Marques, Gustavo S. Feitosa and Thais S. de Oliveira
Proceedings 2026, 137(1), 68; https://doi.org/10.3390/proceedings2026137068 - 2 Mar 2026
Viewed by 620
Abstract
In hematology, the CRISPR-Cas9 system has emerged as an innovative technology for treating genetic blood diseases, enabling precise DNA editing [...] Full article
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2 pages, 120 KB  
Abstract
Eye Movement Desensitization Ande Reprocessing (EMDR): Therapeutic Approach to Reframe Traumatic Memories
by Juliano Cintra Taveira Tupina Almeida, Pedro Gabriel Rodrigues Gomes, Daniel Carmona Ferreira, Daniel Mota Cardoso, Kevin Prates Bellorio, Carlos Gustavo Santos and Carlos Nogueira Aucélio
Proceedings 2026, 137(1), 69; https://doi.org/10.3390/proceedings2026137069 - 2 Mar 2026
Viewed by 433
Abstract
Introduction: EMDR is a therapeutic method used to treat traumatic memories and Post-traumatic Stress Disorder (PTSD), based on the idea that eye movements, similar to those observed during Rapid Eye Movement (REM) sleep, can help in the processing of traumatic memories [...] Full article
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2 pages, 120 KB  
Abstract
Impact of Neuroparasitic Diseases on Neurological Development in Brazilian Children: A Systematic Review
by Lavinia H. A. Torres, Ana C. F. Leite, Isaac D. S. V. Prado, Luigi Gallo, Mateus G. C. Soares, Samuel C. Silva and Carlos N. Aucélio
Proceedings 2026, 137(1), 70; https://doi.org/10.3390/proceedings2026137070 - 2 Mar 2026
Viewed by 546
Abstract
Introduction: Neuroparasitic infections represent a public health challenge among children and adolescents in Brazil, causing clinical manifestations that range from mild symptoms to severe neurological sequelae [...] Full article
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2 pages, 121 KB  
Abstract
Evaluation of the Mechanical Resistance of 3D-Printed Bone Structures for Fracture Treatment in the Elderly: A Proposal for Innovation and Rehabilitation
by Cassiana M. Melo, Fabrício W. B. Martins, Linconl A. O. Benito and Rosana C. Benito
Proceedings 2026, 137(1), 71; https://doi.org/10.3390/proceedings2026137071 - 2 Mar 2026
Viewed by 250
Abstract
Introduction: Advances in additive manufacturing technologies have driven significant transformations in various sectors, particularly in healthcare [...] Full article
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2 pages, 109 KB  
Abstract
Impacts of Geo Helminthiasis on the Growth and Development of Children: A Literature Review
by Ludmylla E. S. C. Goncalves, Neudson J. Martinho, Natalia C. Aquino, Dhennyfer K. Gomes, Ana Karolina A. Broiano, Maria Clara S. Correia and Priscila S. Costa
Proceedings 2026, 137(1), 72; https://doi.org/10.3390/proceedings2026137072 - 2 Mar 2026
Viewed by 276
Abstract
Introduction: Soil-transmitted helminthiases, classified as neglected tropical diseases, represent a significant public health problem in regions characterized by poor sanitation and social vulnerability [...] Full article
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2 pages, 174 KB  
Abstract
Epidemiological Trends of Melanoma in Brazil (2013–2023): Analysis of the Brazilian DATASUS Database
by Maria G. B. Rodrigues, Samuel O. L. Barbosa, Bruno S. L. Dallago, Shélida V. Braz, Sophia A. Portela, Thomás W. E. Lima, João S. P. Barbosa, Renata A. E. Dantas and Silvia Pereira
Proceedings 2026, 137(1), 73; https://doi.org/10.3390/proceedings2026137073 - 2 Mar 2026
Viewed by 497
Abstract
Introduction: Melanoma is a malignant neoplasm associated with excessive ultraviolet (UV) radiation exposure [...] Full article
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2 pages, 167 KB  
Abstract
In Vitro Antimicrobial Activity of Vetiver Essential Oil (Chrysopogon zizanioides)
by Hayla B. T. Ruas, Letícia F. S. Rodrigues, Carla A. Bilac, Daniel O. Freire, Rebeca Dias dos Santos, Yan M. S. Ribeiro, Thálisson D. D. Cardoso, Bruno A. Prado, Daniela C. Orsi and Izabel C. R. Silva
Proceedings 2026, 137(1), 74; https://doi.org/10.3390/proceedings2026137074 - 2 Mar 2026
Viewed by 497
Abstract
Introduction: Vetiver (Chrysopogon zizanioides) is a perennial grass traditionally used in folk medicine due to the properties of its essential oil, mainly obtained from the roots, which exhibits antimicrobial, antiparasitic, anti-inflammatory, antifungal, and antioxidant activities [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 147 KB  
Abstract
Epidemiological Profile of Hepatitis A Outbreaks in the Southeast Region (2020–2023)
by Eduarda S. Fabri, Heitor A. B. Da Silva, Maria H. R. Marques, Thiago R. Silva, Lavinia M. Barbosa and Romulo D. A. Andrade
Proceedings 2026, 137(1), 75; https://doi.org/10.3390/proceedings2026137075 - 2 Mar 2026
Viewed by 351
Abstract
Hepatitis is a group of inflammatory liver diseases affecting a vital organ responsible for essential metabolic functions [...] Full article
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2 pages, 130 KB  
Abstract
Innovative Biomaterial-Based Therapies Accelerate Wound Regeneration and Modulate Inflammation in Diabetic Mice
by Gildemar José Bezerra Crispim, Gabriella de Oliveira Silva, Graziela Anselmo Joanitti, Cleia Abrantes da Silva, Amilcar Sabino Damazo and Marcela Lemos Brettas Carneiro
Proceedings 2026, 137(1), 76; https://doi.org/10.3390/proceedings2026137076 - 2 Mar 2026
Viewed by 247
Abstract
Introduction: Diabetes is a major clinical challenge due to delayed tissue repair, persistent inflammation, and high risk of infection [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 149 KB  
Abstract
Innovation in Anxiety Management: An Integrative Review of Genetic, Physiological, and Behavioral Factors
by Helen D. S. C. Souza, Sávio C. Souza, Heitor C. Souza, Victor I. Maciel, Raíssa Pimentel Naves, Rafaela T. Cruvinel, Maria Fernanda C. Goulart, Nicole V. Cruvinel and Sérgio P. Souza
Proceedings 2026, 137(1), 77; https://doi.org/10.3390/proceedings2026137077 - 2 Mar 2026
Viewed by 350
Abstract
Introduction: Anxiety is a complex pathology modulated by the interaction among genetic vulnerabilities, neural physiology, inflammatory system activity, and behavioral and environmental factors such as parental stress or lifestyle [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 162 KB  
Abstract
Nanoemulsion-Based Dressing: FTIR Spectroscopic Characterization
by Paulo H. Oliveira, Patrícia A. Oliveira, Gabriella O. Silva, Sebastião W. Silva, Glécia V. S. Luz, Graziella A. Joanitti and Marcella L. B. Carneiro
Proceedings 2026, 137(1), 78; https://doi.org/10.3390/proceedings2026137078 - 3 Mar 2026
Viewed by 544
Abstract
Introduction: Fourier-transform infrared spectroscopy (FTIR) is a key technique in the characterization of biomaterials, allowing the identification of functional groups and the verification of bioactive compound incorporation in nanostructured systems. In this study, the spectral signature of raw materials used in the formulation [...] Read more.
Introduction: Fourier-transform infrared spectroscopy (FTIR) is a key technique in the characterization of biomaterials, allowing the identification of functional groups and the verification of bioactive compound incorporation in nanostructured systems. In this study, the spectral signature of raw materials used in the formulation of a nanoemulsion with curcumin, sunflower oil, annatto oil, and Cremophor applied in the production of a dressing consisting of a natural latex biomembrane (Hevea brasiliensis) was evaluated. Methodology: FTIR spectra were obtained from isolated raw materials (curcumin, vegetable oils, and Cremophor) and from the curcumin-containing nanoemulsion formulation, aiming to compare their spectral profiles and identify possible chemical interactions. Results: Curcumin showed characteristic bands around 3328–3508 cm−1 (–OH), 1637 cm−1 (C=O and conjugated C=C), and 1505 cm−1 (aromatic ring), confirming its polyphenolic structure. Sunflower oil exhibited an intense peak at 1744 cm−1 (ester carbonyl), associated with its triglyceride composition, while annatto oil showed a band at 1633 cm−1 (conjugated C=O), indicative of bixine and carotenoids. Cremophor presented peaks at 3460 cm−1 (–OH) and 1726 cm−1 (C=O), typical of ethoxylated surfactants. In the curcumin-containing nanoemulsion, the Cremophor spectral profile predominated, but new bands between 1511 and 1637 cm−1, associated with curcumin, confirmed its incorporation into the matrix. Conclusion: The FTIR results confirmed the preservation of the spectral signatures of the raw materials and the successful integration of curcumin into the nanoemulsion, reinforcing its potential for application in biomaterial-based dressings Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 133 KB  
Abstract
PCSK9 E670G Polymorphism and Its Clinical Implications in Obese Elderly Patients Undergoing Bariatric Surgery
by Dante M. T. Teixeira, Calliandra M. S. Silva, Matheus G. Castro, Gustavo M. Ferreira, Juliana M. A. Seixas, Caroline F. Fratelli, Rosana C. Benito, Evelyn M. Kogawa, Linconl A. O. Benito and Izabel C. R. Silva
Proceedings 2026, 137(1), 79; https://doi.org/10.3390/proceedings2026137079 - 28 Feb 2026
Viewed by 223
Abstract
Introduction: The PCSK9 gene encodes the NARC-1 protein, a key regulator of cholesterol metabolism [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 109 KB  
Abstract
Prion Diseases and the Brain: A Narrative Review of Region-Specific Neurodegeneration in Transmissible Spongiform Encephalopathies
by Caio C. Carvalho and Maria C. E. S. Barros
Proceedings 2026, 137(1), 80; https://doi.org/10.3390/proceedings2026137080 - 3 Mar 2026
Viewed by 572
Abstract
Introduction: Prion diseases, or Transmissible Spongiform Encephalopathies (TSEs), are fatal neurodegenerative disorders caused by protein misfolding [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 152 KB  
Abstract
Oncogenomics as a Therapeutic Approach in Anaplastic Thyroid Carcinoma: A Literature Review
by Maria G. B. Rodrigues, Samuel O. L. Barbosa, Pedro R. Vaz, Sophia Marciel, Bruno S. L. Dallago and Shélida V. Braz
Proceedings 2026, 137(1), 81; https://doi.org/10.3390/proceedings2026137081 - 3 Mar 2026
Viewed by 553
Abstract
Introduction: Anaplastic Thyroid Carcinoma (ATC) is a rare and highly lethal neoplasm [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 134 KB  
Abstract
Kombucha with Clitoria Ternatea: A Functional Beverage with High Antioxidant Potential
by Marta Oliveira de Araújo, Hugo Raphael Lima Araujo, Karolina Oliveira Gomes, Calliandra Maria de Souza Silva, Izabel Cristina Rodrigues da Silva and Daniela Castilho Orsi
Proceedings 2026, 137(1), 82; https://doi.org/10.3390/proceedings2026137082 - 2 Mar 2026
Viewed by 520
Abstract
Introduction: Kombucha is a fermented beverage traditionally prepared with green tea and a symbiotic culture of bacteria and yeast (SCOBY), known for its health-promoting properties [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 124 KB  
Abstract
A Critical Review of Traumatic Brain Injury Rehabilitation in Sports: Multidisciplinary Therapy and Athlete Recovery
by Eduarda R. Martins, Cauã F. Martins, Igor G. M. Quirido, Mariana Y. Rodrigues and Carlos N. Aucélio
Proceedings 2026, 137(1), 83; https://doi.org/10.3390/proceedings2026137083 - 3 Mar 2026
Viewed by 286
Abstract
Introduction: Traumatic Brain Injury (TBI) is a disruption of normal brain function commonly triggered by falls, violence, motor vehicle accidents, or contact sports, and is considered one of the leading causes of death and disability [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 121 KB  
Abstract
The Impact of Incomplete Notification Forms on Leprosy Surveillance
by Ludmylla E. S. C. Goncalves, Allana S. Milanski, Thiago V. S. Truppel, Jason H. Batista, Dayelle S. Silva and Neudson J. Martinho
Proceedings 2026, 137(1), 84; https://doi.org/10.3390/proceedings2026137084 - 4 Mar 2026
Viewed by 246
Abstract
Introduction: The effectiveness of leprosy control actions depends on the quality of records in notification forms and medical charts [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 121 KB  
Abstract
Induction of Seizures from DREADDs in Rodents
by Giovanna F. Oliveira, Maria Camila Acero-Castillo, Aline Borges, Márcia Mortari, Patrick A. Forcelli and Rafael S. Maior
Proceedings 2026, 137(1), 85; https://doi.org/10.3390/proceedings2026137085 - 2 Mar 2026
Viewed by 326
Abstract
Introduction: Temporal lobe epilepsy (TLE) is clinically relevant due to its severity and the high percentage of patients resistant to available medications [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 120 KB  
Abstract
Genetic Improvement of Solanum tuberosum for Sustainable Space Agriculture: A Review
by Débora N. Anjos and Scarlat G. R. Anjos
Proceedings 2026, 137(1), 86; https://doi.org/10.3390/proceedings2026137086 - 4 Mar 2026
Viewed by 323
Abstract
Introduction: During long-duration space missions, astronauts face several physiological challenges due to microgravity, radiation, isolation, and confinement, which can lead to neuroinflammation, cognitive impairments, and other long-term effects [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 129 KB  
Abstract
Beyond Emergency: Intersectoral Strategies for Sustainable Dengue Control in the Federal District of Brazil
by Matheus H. L. Pereira and Scarlat G. R. dos Anjos
Proceedings 2026, 137(1), 87; https://doi.org/10.3390/proceedings2026137087 - 27 Feb 2026
Viewed by 213
Abstract
Introduction: In 2024, the Federal District of Brazil faced one of its most severe dengue outbreaks, with record cases and deaths [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 139 KB  
Abstract
The Use of Dermoscopic and Confocal Microscopic Technologies in Oncological Diagnosis: A Literature Review
by Raíssa P. Naves, Heitor C. Souza, Nicole V. Cruvinel, Alicy C. Cruvinel, Ana Júlia S. Guerra, Isabele C. Mortari, Rafaela T. Cruvinel, Sávio C. Souza, Victor I. Maciel and Helen D. S. C. Souza
Proceedings 2026, 137(1), 88; https://doi.org/10.3390/proceedings2026137088 - 4 Mar 2026
Viewed by 249
Abstract
Introduction: Dermoscopy and confocal microscopy are technologies used in neoplasm identification through high-resolution image records [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 135 KB  
Abstract
Biomarkers and Suicidal Ideation in Depression: A Pilot Study Combining Clinical and Laboratory Data
by Gustavo F. Mortari, Manuela A. Pires, Alexandre S. R. Pereira, Marcela M. G. Paes, Antonio A. F. Soares, Larissa S. S. Bonasser, Alexandre P. Baptista, Caroline F. Fratelli, Calliandra M. S. Silva and Izabel C. R. Silva
Proceedings 2026, 137(1), 89; https://doi.org/10.3390/proceedings2026137089 - 4 Mar 2026
Viewed by 297
Abstract
Major Depressive Disorder (MDD) is strongly associated with suicidal behavior [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 165 KB  
Abstract
Modulation of Antioxidant Pathway by Bioactive Peptides: Impact on Post-Thaw Sperm Viability and Motility
by Bruno S. Sá, Ana Gabriela P. Meneses, Sophia A. dos Reis, Natália P. B. Valadares, João B. Nunes, Pedro Paulo R. C. Melo, Andreanne G. Vasconcelos and José Roberto S. A. Leite
Proceedings 2026, 137(1), 90; https://doi.org/10.3390/proceedings2026137090 - 4 Mar 2026
Viewed by 473
Abstract
Introduction: Sperm cryopreservation is a crucial advancement for fertility preservation—whether for social or clinical medical reasons—allowing for the postponement of gamete use and favoring reproductive planning [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 147 KB  
Abstract
3D Cell Culture Models for the Study of New Anti-Inflammatory Drugs: Toxicity and Cell Viability
by Juliano C. T. T. Almeida, Luan B. V. Costa, Vinícius Q. F. Silva, Maria da G. da Silva, Andreanne G. Vasconcelos and José Roberto de S. A. Leite
Proceedings 2026, 137(1), 91; https://doi.org/10.3390/proceedings2026137091 - 4 Mar 2026
Viewed by 432
Abstract
Introduction: In Brazil, pressure ulcer wounds have a significant impact on public health [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 128 KB  
Abstract
Light-Driven Therapies: Antioxidant and Photodynamic Potential of Nanoemulsions
by Jhenyfer B. Santos, Mosar Correa Rodrigues, Graziella A. Joanitti and Marcella L. B. Carneiro
Proceedings 2026, 137(1), 92; https://doi.org/10.3390/proceedings2026137092 - 4 Mar 2026
Viewed by 292
Abstract
Introduction: Curcumin and annatto oil are rich in bioactive compounds with well-documented antioxidant and therapeutic properties; however, their applications are limited by their low solubility and potential toxicity in free forms [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 163 KB  
Abstract
Antibacterial Activity of Polymeric Nanoparticles with Ceftazidime Against ESBL-Producing Klebsiella pneumoniae 
by Lívia S. Menezes, Bianca M. R. Araújo, Rayna K. G. Silva, Antônia C. J. Oliveira, Durcilene A. Silva, Fábio O. S. Ribeiro and Alyne R. A. Nobre
Proceedings 2026, 137(1), 93; https://doi.org/10.3390/proceedings2026137093 - 4 Mar 2026
Viewed by 284
Abstract
Introduction: The resistance of Gram-negative bacteria to ceftazidime (CAZ) represents a global challenge, limiting therapeutic strategies and hindering infection control [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 158 KB  
Abstract
Cell-Free Supernatants of Lactobacillus gasseri and Lactobacillus crispatus Exhibit Antimicrobial Activity Against Resistant Pathogens
by Isabelle R. Oliveira, Carla A. Bilac, Rebeca D. Santos, Letícia F. S. Rodrigues, Daniel O. Freire, Nathália L. R. Freire, Priscila B. F. Arquelau, Izabel C. R. Silva, Livia C. L. S. Barreto and Daniela C. Orsi
Proceedings 2026, 137(1), 94; https://doi.org/10.3390/proceedings2026137094 - 4 Mar 2026
Viewed by 261
Abstract
Introduction: Lactobacillus gasseri and Lactobacillus crispatus are lactic acid bacteria from the vaginal and intestinal microbiota that produce bioactive metabolites with antimicrobial potential [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 129 KB  
Abstract
Salivary Metabolomic Profile in Individuals with Different Stages of Renal Function: A Scoping Review
by Letícia D. Medeiros, Aline L. de Oliveira, Cristine M. Stefani, Solange Baraldi and Laudimar A. Oliveira
Proceedings 2026, 137(1), 95; https://doi.org/10.3390/proceedings2026137095 - 4 Mar 2026
Viewed by 231
Abstract
Introduction: Saliva is a complex biofluid with multiple physiological roles and a rich molecular composition, including proteins, metabolites, microorganisms, immune cells, lipids, enzymes, and other compounds [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 168 KB  
Abstract
Development and Validation of a Printed Educational Material to Promote Medication Adherence Among Elderly with Hypertension: A Methodological Study
by Silvana Schwerz Funghetto, Alayne Laryssa Martins Pereira, Marina Morato Stival, Giovana Alcântara, Izabel Rodrigues da Silva, Luciano Ramos de Lima, Margô Gomes de Oliveira Karnikowski, Aline Farias Oliveira, Yuri Gustavo de Sousa Barbalho and Raíza Rana de Souza Lima Trombini
Proceedings 2026, 137(1), 96; https://doi.org/10.3390/proceedings2026137096 - 4 Mar 2026
Viewed by 298
Abstract
Introduction: Systemic arterial hypertension (SAH) is a prevalent chronic condition among the elderly, requiring continuous pharmacological treatment and self-care [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 145 KB  
Abstract
Minimum Inhibitory Concentration of Curcumin and Annatto Oil Nanoemulsions on Staphylococcus aureus with and Without Blue LED Irradiation
by Gabriella de Oliveira Silva, Namuhell Oliveira da Silva, Ildinete Silva Pereira, Graziella A. Joanitti and Marcella L. B. Carneiro
Proceedings 2026, 137(1), 97; https://doi.org/10.3390/proceedings2026137097 - 4 Mar 2026
Viewed by 407
Abstract
Introduction: Nanoemulsions are promising for the improvement of the solubility and bioavailability of poorly water-soluble antimicrobials such as curcumin [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 122 KB  
Abstract
Tofersen: The Use of Antisense Oligonucleotide as a Therapeutic Approach to SOD1-Associated Amyotrophic Lateral Sclerosis—A Literature Review
by Isaac D. S. V. Prado, Ana C. F. Leite, Lavínia H. A. Torres, Luigi Gallo, Mateus G. C. Soares, Samuel C. Da Silva and Carlos N. Aucélio
Proceedings 2026, 137(1), 98; https://doi.org/10.3390/proceedings2026137098 - 4 Mar 2026
Viewed by 973
Abstract
Introduction: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that affects motor neurons, causing weakness and atrophy [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 167 KB  
Abstract
Mobile App Improves Adherence to Antihypertensive Treatment in Elderly People with Hypertension: A Randomized Clinical Trial
by Alayne L. M. Pereira, Silvana S. Funghetto, Marina M. Stival, Giovana Alcântara, Izabel R. Silva, Aline F. Oliveira, Yuri G. S. Barbalho and Raíza R. De S. L. Trombini
Proceedings 2026, 137(1), 99; https://doi.org/10.3390/proceedings2026137099 - 4 Mar 2026
Viewed by 417
Abstract
Keywords: hypertension; medication adherence; mobile applications [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 158 KB  
Abstract
Temporal Modulation of Interferon α/γ by LDT409 in Trypanosoma Cruzi-Infected Human Adipocytes
by Vitória F. S. Pessoa, Eduarda P. Correa, Marcelo P. Machado, Emãnuella M. Garcez, Amandda E. Silva-Carvalho, Mariana Hecht, Nadjar Nitz, Juliana L. Carvalho, Luiz Romeiro and Luciana Hagström
Proceedings 2026, 137(1), 100; https://doi.org/10.3390/proceedings2026137100 - 5 Mar 2026
Viewed by 312
Abstract
Introduction: Chagas disease (CD) remains a serious public health problem [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 122 KB  
Abstract
Relationship Between Leprosy and Education in UBS in Cuiabá and Várzea Grande-MT
by Thiago V. S. Truppel, Ludmylla E. S. C. Goncalves, Allana S. Milanski, Jason H. Batista, Dayelle S. Silva and Neudson J. Martinho
Proceedings 2026, 137(1), 101; https://doi.org/10.3390/proceedings2026137101 - 5 Mar 2026
Viewed by 229
Abstract
Introduction: Leprosy remains a major notifiable disease and a neglected public health problem in Brazil [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 123 KB  
Abstract
The Role of Prevention and Diagnosis in Sports-Related Traumatic Brain Injury: A Review
by Mariana Y. Rodrigues, Eduarda R. Martins, Cauã F. Martins, Igor G. M. Quirido and Carlos N. Aucélio
Proceedings 2026, 137(1), 102; https://doi.org/10.3390/proceedings2026137102 - 5 Mar 2026
Viewed by 399
Abstract
Introduction: Traumatic brain injury (TBI) is a disruption of normal brain function caused by falls, violence, car accidents, and contact sports [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 119 KB  
Abstract
Social Challenges in the Diagnosis and Control of HIV: A Review
by Anna Cecília S. S. Pinheiro and Scarlat G. R. dos Anjos
Proceedings 2026, 137(1), 103; https://doi.org/10.3390/proceedings2026137103 - 5 Mar 2026
Viewed by 334
Abstract
Introduction: Despite advancements in knowledge and access to information about HIV transmission and treatment, Brazil has experienced a growing incidence of infections among young people and women, including pregnant individuals [...] Full article
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2 pages, 141 KB  
Abstract
Trends in Delivery Types and Maternal Profiles in the Public Health System of the Federal District, Brazil (2015–2024)
by Renata de Souza Freitas and Fernando José Silva de Araújo
Proceedings 2026, 137(1), 104; https://doi.org/10.3390/proceedings2026137104 - 5 Mar 2026
Viewed by 284
Abstract
Introduction: Understanding delivery trends is crucial for maternal and neonatal health planning [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 151 KB  
Abstract
Effects of Cannabidiol (CBD) on the Treatment of Anxiety and Depression in Adults: A Literature Review
by Heitor C. Souza, Raíssa P. Naves, Sávio C. Souza, Rafaela T. Cruvinel, Maria Fernanda O. Melo, Isabele C. Mortari, Victor I. Maciel, Raquel Naves, Ayla S. Marques and Helen D. S. C. Souza
Proceedings 2026, 137(1), 105; https://doi.org/10.3390/proceedings2026137105 - 5 Mar 2026
Viewed by 1354
Abstract
Introduction: Anxiety and depression are among the most prevalent mental disorders globally, significantly impacting public health, quality of life, and individuals’ overall functioning [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 120 KB  
Abstract
Nursing Practice and Bioethical Aspects of Oral Contraceptive Use in Primary Care: Literature Review
by Andrey Hudson I. M. de Araújo, Brunna L. Neves, Ana Cláudia A. Valladares-Torres and Diane Maria S. K. Lago
Proceedings 2026, 137(1), 106; https://doi.org/10.3390/proceedings2026137106 - 5 Mar 2026
Viewed by 276
Abstract
Introduction: Women’s health policies in Brazil guarantee family planning and access to contraceptives through the Unified Health System (SUS), with oral contraceptives being the most used [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 148 KB  
Abstract
Indicators of Anxiety and Depression Among Health Science Students at a Public University in the Federal District
by Andrey Hudson I. M. De Araújo, Kelb B. Santos, Diane Maria S. K. Lago, Ana Cláudia A. Valladares-Torres, Andrea D. Gallassi and Mariana Idnês De O. I. Mendes
Proceedings 2026, 137(1), 107; https://doi.org/10.3390/proceedings2026137107 - 5 Mar 2026
Viewed by 322
Abstract
Introduction: Health, according to the WHO, includes physical, mental, and social well-being [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 142 KB  
Abstract
Genetic Marker for Stroke: NOS3-786 T/C Polymorphism Predicts Risk and Recovery Outcomes
by Ligia C. A. Cardoso-Duarte, Felipe S. A. Borges, Renata S. Freitas, Daniel O. Freire, Hélia C. De Souza, Luzitano B. Ferreira, Calliandra M. S. Silva and Izabel C. R. Da Silva
Proceedings 2026, 137(1), 108; https://doi.org/10.3390/proceedings2026137108 - 5 Mar 2026
Viewed by 393
Abstract
Introduction: Nitric oxide (NO) plays a crucial role in regulating cerebral blood flow and neuronal signaling [...] Full article
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2 pages, 119 KB  
Abstract
Synergistic Effects of Low-Level UV and Hydrogen Peroxide in Reducing Airborne Influenza A (H1N1)
by Arlo Bowe, Paula Jaramillo, Oliver C. Dsa and Angela Southey
Proceedings 2026, 137(1), 109; https://doi.org/10.3390/proceedings2026137109 - 6 Mar 2026
Viewed by 437
Abstract
Introduction: Influenza A (H1N1) is a highly contagious respiratory virus transmitted via droplets and aerosols, representing a major public health challenge [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 144 KB  
Abstract
Nanoparticles in Parkinson’s Treatment: A Review on the Impact of Nanoparticles Carrying Dopamine Precursors Across the Blood–Brain Barrier
by Amanda S. N. Oliveira, Isabela M. Pereira, Isabele C. Mortari, Júlia S. Carvalho, Maria Eduarda F. Andrade, Nicole V. Cruvinel, Ricardo S. Bernardes, Victor I. Maciel, Heitor C. Souza and Letícia G. L. Morais
Proceedings 2026, 137(1), 110; https://doi.org/10.3390/proceedings2026137110 - 6 Mar 2026
Viewed by 488
Abstract
Introduction: Parkinson’s disease is a major neurodegenerative disorder characterized by dopamine depletion in the basal ganglia, resulting in various motor and non-motor symptoms [...] Full article
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2 pages, 130 KB  
Abstract
Subclinical Leprosy Detection in Patients Undergoing Immunosuppressive and Immunobiological Therapy in the Federal District
by Jéssica L. S. da Costa, Arthur B. Fernandes, Cleia A. Silva, Luciana P. F. Martins, Maria G. Silva and Amílcar S. Damazo
Proceedings 2026, 137(1), 111; https://doi.org/10.3390/proceedings2026137111 - 6 Mar 2026
Viewed by 371
Abstract
Introduction: Leprosy is a chronic infectious disease that affects the skin and peripheral nerves, with clinical manifestations depending on the host’s immune response to Mycobacterium leprae [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 138 KB  
Abstract
Analysis of Varicella Vaccination Coverage in the Central-West Region of Brazil, 2023–2025
by Júlia M. C. Soares, Jonas L. Almeida, Nathalia L. S. Cordeiro and Thais S. de Oliveira
Proceedings 2026, 137(1), 112; https://doi.org/10.3390/proceedings2026137112 - 9 Mar 2026
Viewed by 339
Abstract
Introduction: Chickenpox (varicella) is a highly contagious viral disease that can cause severe complications in some population groups [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 154 KB  
Abstract
From Genes to Surgery: How NOS3 Intron 4 Shapes Obesity Risk and Metabolic Outcomes
by Jéssica B. Macêdo, Carine Royer, Dante M. T. Teixeira, Calliandra M. S. Silva, Rosana C. Benito, Evelyn M. Kogawa, Linconl A. O. Benito and Izabel C. R. Silva
Proceedings 2026, 137(1), 113; https://doi.org/10.3390/proceedings2026137113 - 2 Mar 2026
Viewed by 218
Abstract
Introduction: Obesity is a multifactorial disease with high global prevalence and substantial metabolic–cardiovascular burden [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 154 KB  
Abstract
In Vitro Hygienic and Sanitary Check of Minimally Processed Fruits and the Incidence of Cases in Brazil
by Isabela M. Freitas, Ana Clara Saraiva de Souza and Rachel C. P. S. Caetano
Proceedings 2026, 137(1), 114; https://doi.org/10.3390/proceedings2026137114 - 9 Mar 2026
Viewed by 412
Abstract
Introduction: Fruits contain high nutritional value, but when consumed without proper hygiene, they pose health risks to consumers due to the presence of bacteria [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 124 KB  
Abstract
From Dissection to Neuromodulation: Anatomical–Clinical Brachial Plexus Framework for Pain Management in Plexopathies
by Daniel Assunção Aires Moreira, Catarina Quezado Duval and Enzo Kauan Mendes Rodrigues
Proceedings 2026, 137(1), 115; https://doi.org/10.3390/proceedings2026137115 - 9 Mar 2026
Viewed by 295
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Introduction: Brachial plexopathies often associated with refractory neuropathic pain [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 143 KB  
Abstract
When a Cough Hides a Rare Diagnosis: An Inflammatory Myofibroblastic Tumor in a Pediatric Patient—A Case Report
by João P. S. Aguiar, Mateus N. Batista, Thais I. A. dos Santos, Maria E. A. G. Santos, Ghabriel A. Amorim, Raphael D. O. M. Ferreira, Arthur H. Câmara, Ana C. A. de Oliveira, Vitor J. G. de Oliveira and Carlos N. Aucélio
Proceedings 2026, 137(1), 116; https://doi.org/10.3390/proceedings2026137116 - 9 Mar 2026
Viewed by 377
Abstract
Introduction: An inflammatory myofibroblastic tumor (IMT) is a type of tumor that is considered rare in the literature; it has a highly nonspecific and variable clinical profile, often being confused with other pathologies [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 148 KB  
Abstract
Leishmaniasis and Economic Invisibility: Epidemiology of a Neglected Disease and the Limits of Market Logic in Brazilian Healthcare—Epidemiological Study
by Maria G. da Silva, Bruno S. Sá, Camila N. Menezes, Eliane L. de Freitas, Jessica L. S. da Costa, Cleia A. da Silva and Amilcar S. Damazo
Proceedings 2026, 137(1), 117; https://doi.org/10.3390/proceedings2026137117 - 10 Mar 2026
Viewed by 428
Abstract
Introduction: The low financial profitability of the treatment of neglected diseases, such as cutaneous leishmaniasis (CL), results in outdated treatments with limited efficacy and high toxicity [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 143 KB  
Abstract
Topical Use of Pterodon pubescens Extract (LDT-PPH) in Healing of Neuropathic Ulcer in Leprosy: Case Report
by Camila N. Menezes, Maria G. Silva, Luiz A. S. Romeiro, Naiara D. Santos and Amílcar S. Damazo
Proceedings 2026, 137(1), 118; https://doi.org/10.3390/proceedings2026137118 - 10 Mar 2026
Viewed by 420
Abstract
Introduction: Hansen’s disease remains a public health challenge associated with neuropathic ulcers that are difficult to heal [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 140 KB  
Abstract
Short-Chain Fatty Acids Induce Cell Death in Glioblastoma Cells via Distinct Mechanisms
by Elizabete Cristina Iseke Bispo, Germano Aguiar Ferreira, Ricardo Titze Almeida and Felipe Saldanha-Araujo
Proceedings 2026, 137(1), 119; https://doi.org/10.3390/proceedings2026137119 - 11 Mar 2026
Viewed by 306
Abstract
Introduction: Glioblastoma (GBM) is the most common and aggressive type of glioma. Although current treatment strategies are well-established, their effectiveness remains limited. Recent studies have highlighted the potential of short-chain fatty acids (SCFAs)—such as acetate, butyrate, propionate, and valeric acid—as therapeutic agents [...] Read more.
Introduction: Glioblastoma (GBM) is the most common and aggressive type of glioma. Although current treatment strategies are well-established, their effectiveness remains limited. Recent studies have highlighted the potential of short-chain fatty acids (SCFAs)—such as acetate, butyrate, propionate, and valeric acid—as therapeutic agents against various solid tumors. Methodology: We evaluated the cell viability of A172, a GBM cell line, upon treatment with SCFAs using MTT assay. We then investigated the underlying molecular mechanisms of cell death induced by sodium butyrate and valeric acid, using their respective IC50 concentrations via Real-Time qPCR. Results: The IC50 values indicated that A172 cells were more sensitive to sodium butyrate and valeric acid (IC50 = 9.22 mM and 19.04 mM, respectively) than to sodium propionate and sodium acetate (IC50 = 41.21 mM and 121.2 mM, respectively) after 72 h of treatment. In cells treated with sodium butyrate, we observed an increased expression of BAK and decreased expression of P53 and CASP1. Treatment with valeric acid led to upregulation of BCL-2, BAK, and RIPK3, along with downregulation of P53. Conclusions: Our preliminary findings suggest that SCFAs, particularly sodium butyrate and valeric acid, can induce cell death in GBM cells through distinct molecular pathways. While further studies are necessary to elucidate the exact mechanisms, these results support the potential of SCFAs as therapeutic candidates for glioblastoma. Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 119 KB  
Abstract
DEAF1-PDB: An Online Database of Three-Dimensional Structures Obtained by Comparative Modeling of DEAF1-Related Molecules
by Amanda V. S. Santos, Raphael S. Bonadio, Ana K. Bittencourt, Kassandra C. Chaves and Ricardo M. Ramos
Proceedings 2026, 137(1), 120; https://doi.org/10.3390/proceedings2026137120 - 12 Mar 2026
Viewed by 421
Abstract
Introduction: The DEAF1 (Deformed Epidermal Autoregulatory Factor 1) gene is a highly expressed transcription factor in the central nervous system and is essential for embryonic and neuronal development [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 154 KB  
Abstract
Proposal of a Medical Technology for Treating Pressure Injuries: RAPHA® Equipment
by Sâmyla de S. Melo and Mario F. F. Rosa
Proceedings 2026, 137(1), 121; https://doi.org/10.3390/proceedings2026137121 - 12 Mar 2026
Viewed by 250
Abstract
A pressure injury is defined as a localized wound to the skin or to the underlying skin tissue over a bony prominence, caused by pressure and shear [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 138 KB  
Abstract
Literature Review: Nanotechnology as a Therapeutic Tool in the Treatment of Oncological Diseases
by Mateus N. Batista, João P. S. Aguiar, Thais I. A. dos Santos, Maria E. A. G. Santos, Ghabriel A. Amorim, Raphael D. O. M. Ferreira, Arthur H. Câmara, Ana C. A. de Oliveira, Vitor J. G. de Oliveira and Carlos N. Aucélio
Proceedings 2026, 137(1), 122; https://doi.org/10.3390/proceedings2026137122 - 17 Mar 2026
Viewed by 363
Abstract
Introduction: The treatment of tumors faces challenges, such as low specificity for tumor tissue, systemic toxicity, and side effects [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 129 KB  
Abstract
Microalgal Biotechnology Driving Sustainable Bioeconomy: Food, AgriHealth, Bioremediation, and On-Site Biofertilizer Integration
by Natalia Lorena Cancelarich and Antonela Martelli
Proceedings 2026, 137(1), 123; https://doi.org/10.3390/proceedings2026137123 - 17 Mar 2026
Viewed by 348
Abstract
Introduction: Microalgae are emerging as a biotechnological platform driving innovation in the bioeconomy, AgriHealth, and Food Health sectors, producing high-value compounds such as omega-3 fatty acids, proteins, pigments, and antioxidants, while enabling carbon sequestration and wastewater bioremediation within circular economy models [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 142 KB  
Abstract
A Systematic Review of Neuroplasticity Induced by Brain–Computer Interface Combined with Virtual Reality (BCI-VR)
by Maria F. C. Goulart, Victor I. Maciel, Isabele C. Mortari, Sávio C. Souza, Rafaela T. Cruvinel, Ricardo S. Bernardes, Raíssa P. Naves, Maria F. O. Melo, Nicole V. Cruvinel and Helen D. S. C. Souza
Proceedings 2026, 137(1), 124; https://doi.org/10.3390/proceedings2026137124 - 24 Mar 2026
Cited by 1 | Viewed by 424
Abstract
Introduction: Stroke is a leading cause of permanent neurological disability, often accompanied by motor deficits that impair functionality and quality of life [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 118 KB  
Abstract
Transcriptomic Analysis Reveals microRNA Therapeutic Candidates Targeting Chronic Airway Inflammation in Cystic Fibrosis
by Elise Maria O. Albino, Miriam J. Weber and Hugo L. Correa
Proceedings 2026, 137(1), 125; https://doi.org/10.3390/proceedings2026137125 - 24 Mar 2026
Viewed by 316
Abstract
Introduction: Cystic fibrosis (CF) is an autosomal recessive genetic disorder caused by mutations in the CFTR gene, resulting in a production of abnormally thick secretions, chronic airway inflammation, and severe respiratory complications [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 119 KB  
Abstract
Proposal for a Multidimensional Digital Health Instrument for the Screening of Neurodevelopmental Disorders in Children and Adolescents
by Ana C. C. Rocha and Jorge L. L. Zeredo
Proceedings 2026, 137(1), 126; https://doi.org/10.3390/proceedings2026137126 - 24 Mar 2026
Viewed by 283
Abstract
Introduction: The absence of a unified conceptual framework for analyzing algorithmic violence against children and adolescents represents a critical gap in public health [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 140 KB  
Abstract
Development and Functionalization of Magnetic Nanoparticles for Extraction of Circulating DNA (cfDNA): Platform for Liquid Biopsy
by Daniel S. Ramos, Yasmin R. C. L. Albuquerque, Juliano A. Chaker and Fabio Pittella-Silva
Proceedings 2026, 137(1), 127; https://doi.org/10.3390/proceedings2026137127 - 24 Mar 2026
Viewed by 331
Abstract
Introduction: Liquid biopsy is an emerging and promising technique that enables the detection of molecular biomarkers in various body fluids, such as blood, urine, and saliva [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 137 KB  
Abstract
Virtual Reality in Medical Education: A Bibliographic Literature Review on Its Potential to Enhance Clinical and Soft Skills
by Gabriela S. B. Alves, Lucas B. D. A. Corrêa, Renata U. Alves, Alexandre S. R. Pereira, Vanessa A. Pegoraro and Fabiana P. M. C. Leal
Proceedings 2026, 137(1), 128; https://doi.org/10.3390/proceedings2026137128 - 24 Mar 2026
Viewed by 412
Abstract
Introduction: Recent medical undergraduate curricula have integrated technology, such as virtual reality simulators (VRS), enabling ongoing clinical skills training, including the objective structured clinical examination (OSCE), semiology, and professional tools [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 148 KB  
Abstract
Computational Screening of Membrane Protein Epitopes for Vaccine Development Against Trypanosoma brucei 
by Mariana Fochesato, Kayllany P. Santos, Maria E. L. Fernandes, Ytallo C. Sousa, Ygor Victor Ferreira Pinheiro and Leiz Maria Costa Véras
Proceedings 2026, 137(1), 129; https://doi.org/10.3390/proceedings2026137129 - 25 Mar 2026
Viewed by 337
Abstract
Introduction: African trypanosomiasis is a fatal parasitic disease that affects both humans and animals [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 129 KB  
Abstract
Use of Chitosan as a Carrier for the Release of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
by Maria H. R. Marques, Eduarda S. Fabri, Heitor A. B. Da Silva, Thiago R. Silva, Lavinia M. Barbosa, Fernando H. Nascimento and Romulo D. A. Andrade
Proceedings 2026, 137(1), 130; https://doi.org/10.3390/proceedings2026137130 - 25 Mar 2026
Cited by 1 | Viewed by 467
Abstract
Ibuprofen and ketoprofen (NSAIDs) are widely prescribed due to their anti-inflammatory, analgesic, antipyretic, and antithrombotic effects [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 121 KB  
Abstract
Efficacy of Physical Exercise on Sleep Quality in Patients with Mild Cognitive Impairment: A Systematic Review
by Elton F. F. S. Vieira, Lizandra R. Andrade, Raphael L. Olegário and Cláudia Goulart
Proceedings 2026, 137(1), 131; https://doi.org/10.3390/proceedings2026137031 - 25 Feb 2026
Viewed by 315
Abstract
Introduction: Mild cognitive impairment (MCI) is a transitional stage between typical cognitive ageing and dementia, often accompanied by sleep disturbances [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 139 KB  
Abstract
Artificial Intelligence in Risk Stratification of Acute Myocardial Infarction and Mortality: A Narrative Review
by Laiza C. F. Souza, Isadora F. Grande, Beatriz V. Silva, Thomas W. N. Barreiros, Carlos D. M. Fernandes, Nathália R. S. Carneiro, Tiago F. Bossato and Fabiano F. M. da Silva
Proceedings 2026, 137(1), 132; https://doi.org/10.3390/proceedings2026137132 - 31 Mar 2026
Viewed by 404
Abstract
Introduction: Acute Myocardial Infarction (AMI) is one of the leading causes of global mortality, requiring early diagnosis and effective risk stratification [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 114 KB  
Abstract
Literature Review: Cranberry in Preventive Medicine—A Herbal Approach to Recurrent Urinary Tract Infections
by Hizza K. B. Rocha, Lais J. Capistrano and Maria L. S. Almeida
Proceedings 2026, 137(1), 133; https://doi.org/10.3390/proceedings2026137133 - 31 Mar 2026
Viewed by 344
Abstract
Introduction: Urinary tract infections (UTIs) represent a growing health challenge, due to the rise of antimicrobial resistance (AMR) in common pathogens. Bacteria such as Escherichia coli, responsible for 80% of cases, and Pseudomonas aeruginosa, an opportunistic pathogen of concern, have developed effective [...] Read more.
Introduction: Urinary tract infections (UTIs) represent a growing health challenge, due to the rise of antimicrobial resistance (AMR) in common pathogens. Bacteria such as Escherichia coli, responsible for 80% of cases, and Pseudomonas aeruginosa, an opportunistic pathogen of concern, have developed effective virulence mechanisms. These mechanisms include the use of adhesins, such as type 1 and P fimbriae, to attach to uroepithelial cells, and the formation of biofilms, which protect bacteria from immune system and antibiotics, favoring recurrent infections. Methodology: This study is an integrative review based on articles published until 2015, identified in PubMed, Scopus, and Google Scholar using specific keywords. The inclusion criteria considered clinical relevance and the main findings. Results: In this context, cranberry (Vaccinium macrocarpon) emerges as a complementary strategy for the prevention and treatment of UTIs. The fruit is rich in bioactive compounds, particularly type A proanthocyanidins (PACs). The main action of PACs is to inhibit the adhesion of uropathogenic bacteria to the walls of the urinary tract, an effect that extends to type 1 and P fimbriae, which are resistant to other inhibitors. Additionally, studies show that PACs can interfere with quorum sensing, a cellular communication system bacteria use to coordinate biofilm formation. Conclusions: By disrupting this process, cranberries make pathogens more vulnerable to the action of the immune system and medications, possibly controlling the inflammatory response associated with the infection. Clinical evidence, although not always statistically significant, suggests a reduced risk of symptomatic UTIs with consumption of cranberry extract. Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 133 KB  
Abstract
Preclinical Evaluation of the Toxicity of a Nanosystem in a New Murine Model of Gestational Breast Cancer
by Lohara S. de Lima Barboza, Lara S. Almeida, Giovanna Torres, Luisa Vieira, Aline B. S. Santos, Maria A. G. Soler and Laise R. Andrade
Proceedings 2026, 137(1), 134; https://doi.org/10.3390/proceedings2026137134 - 1 Apr 2026
Viewed by 317
Abstract
Introduction: Breast cancer during pregnancy presents a rare yet clinically challenging scenario due to limited therapeutic options that ensure maternal–fetal safety [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 158 KB  
Abstract
Sample Integrity in Respiratory Virus Surveillance: A Study on Volume Loss in Collection Kits at a Public Health Laboratory
by Farah Camila Murtadha, Edejan Heise de Paula, Fernanda Bernardes Luz, Luan Augusto Azevedo Santos, Fernanda Geórgia de Oliveira Andrade Yamada, Fabiano José Queiroz Costa, Grasiela Araújo da Silva and Tânia Portella Costa
Proceedings 2026, 137(1), 135; https://doi.org/10.3390/proceedings2026137135 - 2 Apr 2026
Viewed by 402
Abstract
Introduction: Sample integrity is a critical factor for the reliability of molecular testing in public health laboratories, especially for epidemiological surveillance data [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 157 KB  
Abstract
Optimization of the Chimeric Peptide Chim4 for Cell Selectivity and Proteolysis Stability
by João B. Nunes, Bruno S. Sá, Guilherme H. S. Santos, Izadora C. M. Oliveira, Sonia M. Freitas, Marcelo H. S. Ramada, José R. S. A. Leite and Guilherme D. Brand
Proceedings 2026, 137(1), 136; https://doi.org/10.3390/proceedings2026137136 - 3 Apr 2026
Viewed by 315
Abstract
Introduction: The rise of bacterial resistance has driven the search for new therapies, with antimicrobial peptides (AMPs) emerging as promising candidates [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 165 KB  
Abstract
Antiparasitic Evaluation of Niclosamide Derivatives as Potential Therapeutic Candidates Against Schistosoma mansoni 
by Rayssa A. Cajas, Monique C. Amaro, Lucas Fukui Silva, João Paulo dos S. Fernandes and Josué de Moraes
Proceedings 2026, 137(1), 137; https://doi.org/10.3390/proceedings2026137137 - 3 Apr 2026
Viewed by 394
Abstract
Introduction: Schistosomiasis, caused by trematodes of the genus Schistosoma, remains a major neglected tropical disease affecting over 240 million people, mainly in low-income regions [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 137 KB  
Abstract
Monkeypox from Diagnosis to Treatment: Epidemiological Analysis of Monkeypox in Southern Brazil Using Public SINAN Data (2022–2025)
by Sumara de Freitas, Marilia E. Almeida and Joao B. A. Neto
Proceedings 2026, 137(1), 138; https://doi.org/10.3390/proceedings2026137138 - 7 Apr 2026
Viewed by 407
Abstract
Introduction: Monkeypox (mpox) is an emerging public health concern, with more than 134,000 confirmed cases worldwide by 2025 [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 139 KB  
Abstract
New Pharmacological Perspectives in the Treatment of Fibromyalgia: A Review of Therapeutic Innovations
by Rayanna de O. Silva, Maria Fernanda C. Goulart, Nicole V. Cruvinel, Letícia G. Franco, Maria Eduarda L. Rosa, Amanda S. N. Oliveira, Victor I. Maciel, Letícia G. L. Morais, Helen D. S. C. Souza and Isabele C. Mortari
Proceedings 2026, 137(1), 139; https://doi.org/10.3390/proceedings2026137139 - 7 Apr 2026
Viewed by 558
Abstract
Introduction: Fibromyalgia is a chronic, multifactorial pain syndrome that is difficult to manage and is characterized by neurochemical changes, dysfunction in pain perception mechanisms, inflammatory factors, and psychosocial aspects [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 128 KB  
Abstract
Panorama of Psychological Care in a CER III: Sociodemographic and Clinical Profile
by Rogério F. Bessa, Marcello P. A. Seiffert, Ana I. A. Oliveira and Miguel F. S. Ferreira
Proceedings 2026, 137(1), 140; https://doi.org/10.3390/proceedings2026137140 - 7 Apr 2026
Viewed by 260
Abstract
Introduction: Specialized Rehabilitation Centers (CERs) play a strategic role within the Brazilian Unified Health System (SUS), articulating interdisciplinary practices for people with disabilities [...] Full article
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2 pages, 160 KB  
Abstract
Antifungal and Antioxidant Activities of Guava (Psidium guajava), Peppermint (Mentha piperita), and Patchouli (Pogostemon cablin) Essential Oils
by Julia F. do Carmo, Rebeca D. dos Santos, Sophia T. T. Alves, Daniele M. Silva, Anita M. Meireles, Eduarda R. Mendes, Carla A. Bilac, Letícia F. S. Rodrigues, Izabel C. R. Silva and Daniela C. Orsi
Proceedings 2026, 137(1), 141; https://doi.org/10.3390/proceedings2026137141 - 7 Apr 2026
Viewed by 390
Abstract
Introduction: Essential oils (EO), rich in bioactive compounds, possess diverse biological properties [...] Full article
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2 pages, 139 KB  
Abstract
Diagnostic Innovation vs. Sustainable Disposal: The Waste Dilemma in RT-qPCR Testing and Its Ecological and Financial Costs to Public Health
by Luan A. A. Santos, Edejan H. Paula, Farah C. Murtadha, Fernanda Y. G. O. Andrade, Fabiano J. Q. Costa, Grasiela A. Silva and Tânia P. Costa
Proceedings 2026, 137(1), 142; https://doi.org/10.3390/proceedings2026137142 - 7 Apr 2026
Viewed by 305
Abstract
Introduction: RT-qPCR represents a crucial diagnostic innovation in the epidemiological surveillance of respiratory viruses such as SARS-CoV-2 and influenza [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 160 KB  
Abstract
Characterization of Mesenchymal Stem Cells for Use in Advanced Therapies
by Daiany S. Dobuchak, Vinicius Marchiori-Silva, Fernando C. Pereira, Carolina M. C. Oliveira Souza, João C. Zielak and Moira P. Leão
Proceedings 2026, 137(1), 143; https://doi.org/10.3390/proceedings2026137143 - 7 Apr 2026
Viewed by 449
Abstract
Introduction: Umbilical cord-derived mesenchymal stem cells, especially from Wharton jelly (WJ-MSCs), are a promising source for regenerative medicine due to their low immunogenicity, immunomodulatory properties, and ethical sourcing [...] Full article
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2 pages, 130 KB  
Abstract
The Development of Technological Support for Multiprofessional Rehabilitation Care in the SUS
by Miguel F. S. Ferreira, Ana I. A. Oliveira, Leonardo J. M. Costa, Lygia C. Silva, Lauro L. S. Pessoa, Marcilene A. Pinheiro, Perla J. C. Barbosa and Rogério F. B. Bessa
Proceedings 2026, 137(1), 144; https://doi.org/10.3390/proceedings2026137144 - 8 Apr 2026
Viewed by 285
Abstract
Introduction: This paper describes the design and development of a technological support system for managing multidisciplinary care in Specialized Rehabilitation Centers (CER) within the Brazilian Unified Health System (SUS) [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 137 KB  
Abstract
Artificial Intelligence in Lung Cancer Screening: From Innovation to Clinical Impact—A Narrative Review
by Carlos Daniel M. Fernandes, Nathalia R. S. Carneiro, Kauan G. Amaral, Laiza C. F. Souza and Gilda E. O. Fonseca
Proceedings 2026, 137(1), 145; https://doi.org/10.3390/proceedings2026137145 - 8 Apr 2026
Viewed by 402
Abstract
Introduction: Lung cancer remains one of the greatest challenges in public health, with high mortality largely due to late diagnosis [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 149 KB  
Abstract
Myopia in the Digital Era: An Integrative Review on the Impact of Screen Exposure on the Vision of Children Aged 6 to 12 Years
by Letícia G. L. Morais, Ricardo S. Bernardes, Nicole V. Cruvinel, Heitor C. Souza, Alicy C. Cruvinel, Letícia G. Franco, Maria Eduarda F. Andrade, Isabela M. Pereira, Rayanna O. Silva and Helen D. S. C. Souza
Proceedings 2026, 137(1), 146; https://doi.org/10.3390/proceedings2026137146 - 8 Apr 2026
Viewed by 356
Abstract
Introduction: The increase in childhood myopia in recent decades represents a public health challenge [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 142 KB  
Abstract
Continuous Glucose Monitoring Technologies in Children with Type 1 Diabetes: An Integrative Review of Efficacy and Adherence over the Past Five Years
by Letícia G. L. Morais, Rafaela T. Cruvinel, Maria F. O. Melo, Heitor C. Souza, Alicy C. Cruvinel, Letícia G. Franco, Maria E. F. Andrade, Isabela M. Pereira, Sávio C. Souza and Helen D. S. C. Souza
Proceedings 2026, 137(1), 147; https://doi.org/10.3390/proceedings2026137147 - 8 Apr 2026
Viewed by 329
Abstract
Introduction: Type 1 diabetes mellitus (DM1) is a common chronic autoimmune disease in childhood, characterized by absolute insulin deficiency [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 109 KB  
Abstract
Assessing Lexical Diversity in Pharmaceutical Leaflets Using Type-Token Ratio for AI-Generated Inclusive Video Leaflets
by Yuri M. C. Luz and Bianca F. O. Camargo
Proceedings 2026, 137(1), 148; https://doi.org/10.3390/proceedings2026137148 - 10 Apr 2026
Viewed by 305
Abstract
Introduction: Low health literacy limits patient understanding of pharmaceutical leaflets [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 140 KB  
Abstract
Sleep Deprivation and Its Consequences on Neuropsychomotor Development in Children: A Systematic Review
by Maria Eduarda. L. Rosa, Victor I. Maciel, Rayanna O. Silva, Ricardo S. Bernardes, Nicole V. Cruvinel, Maria Eduarda. F. Andrade, Isabela M. Pereira, Amanda S. N. Oliveira, Júlia S. Carvalho and Helen. D. S. C. Souza
Proceedings 2026, 137(1), 149; https://doi.org/10.3390/proceedings2026137149 - 9 Apr 2026
Viewed by 282
Abstract
Introduction: Sleep is essential for the neuropsychomotor development of children and adolescents, influencing learning, attention, memory, and emotional regulation [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 137 KB  
Abstract
Epidemiological Analysis of Monkeypox in Northeastern Brazil: Sex, Race, Age and STIs with SINAN Data (2022–2025)
by Marilia Elias de Almeida, Sumara De Freitas, Glécia Virgolino Da Silva Luz and João Beccon De Almeida Neto
Proceedings 2026, 137(1), 150; https://doi.org/10.3390/proceedings2026137150 - 16 Apr 2026
Viewed by 4101
Abstract
Introduction: Monkeypox (mpox) is a viral zoonosis that, by early 2025, surpassed 134,000 confirmed cases worldwide [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 151 KB  
Abstract
In Vitro Comparative Study of the Viability and Adhesion of Wharton’s Jelly Mesenchymal Stem Cells on Different Scaffolds
by Daiany S. Dobuchak, Luana Garcia, Carolina M. C. Oliveira Souza, Deise S. S. Paz, Moira Pedroso Leão and João C. Zielak
Proceedings 2026, 137(1), 151; https://doi.org/10.3390/proceedings2026137151 - 17 Apr 2026
Viewed by 370
Abstract
Introduction: In regenerative medicine, there is a growing demand for innovative strategies to treat difficult-to-heal cutaneous wounds [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
2 pages, 121 KB  
Abstract
Preclinical Evaluation of the Biodistribution of AuPLU/AlClPc (Gold–Pluronic Associated with Phthalocyanine) in a Novel Murine Model of Gestational Breast Cancer
by Lara S. Almeida, Lohara S. de Lima Barboza, Giovanna Torres, Luísa Vieira, Aline B. S. Santos, Maria A. G. Soler and Laise R. Andrade
Proceedings 2026, 137(1), 152; https://doi.org/10.3390/proceedings2026137152 - 27 Apr 2026
Viewed by 259
Abstract
Introduction: Breast cancer during pregnancy (GBC) is a rare and challenging condition due to the limited availability of safe and effective therapies for both mother and fetus [...] Full article
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
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