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Veterinary Sciences, Volume 7, Issue 2

2020 June - 45 articles

Cover Story: Tumors of mesenchymal origin are rarely reported in the pancreas. Therefore, this study characterized 17 feline nonepithelial pancreatic tumors, including their clinical data, histopathology, and immunohistochemistry. Selected pancreatic and inflammatory serum parameters were recorded, when available. The neoplasms were characterized as round cell tumors (n = 13) or spindle cell tumors (n = 4). Round cell tumors included 12 lymphomas and one mast cell tumor in ectopic splenic tissue within the pancreas. Spindle cell tumors included two hemangiosarcomas, one pleomorphic sarcoma, and one fibrosarcoma. These are the first descriptions of a pancreatic pleomorphic sarcoma and a mast cell tumor in accessory spleens within the feline pancreas. View this paper.
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Articles (45)

  • Review
  • Open Access
120 Citations
16,810 Views
20 Pages

Infectious Bronchitis Virus Evolution, Diagnosis and Control

  • Matteo Legnardi,
  • Claudia Maria Tucciarone,
  • Giovanni Franzo and
  • Mattia Cecchinato

RNA viruses are characterized by high mutation and recombination rates, which allow a rapid adaptation to new environments. Most of the emerging diseases and host jumps are therefore sustained by these viruses. Rapid evolution may also hinder the und...

(This article belongs to the Special Issue Trends in Poultry Diseases)
  • Review
  • Open Access
36 Citations
13,058 Views
26 Pages

Palmitoylethanolamide and Related ALIAmides: Prohomeostatic Lipid Compounds for Animal Health and Wellbeing

  • Enrico Gugliandolo,
  • Alessio Filippo Peritore,
  • Cristian Piras,
  • Salvatore Cuzzocrea and
  • Rosalia Crupi

Virtually every cellular process is affected by diet and this represents the foundation of dietary management to a variety of small animal disorders. Special attention is currently being paid to a family of naturally occurring lipid amides acting thr...

  • Article
  • Open Access
8 Citations
5,412 Views
18 Pages

DNA methylation of different gene components, including different exons and introns, or different lengths of exons and introns is associated with differences in gene expression. To investigate the methylation of porcine gene components associated wit...

  • Article
  • Open Access
20 Citations
11,191 Views
12 Pages

Public Perceptions of Veterinarians from Social and Online Media Listening

  • Nicole Widmar,
  • Courtney Bir,
  • John Lai and
  • Christopher Wolf

The public perception of the veterinary medicine profession is of increasing concern given the mounting challenges facing the industry, ranging from student debt loads to mental health implications arising from compassion fatigue, euthanasia, and oth...

(This article belongs to the Section Veterinary Education, Veterinary Communication and Animal Behavior)
  • Article
  • Open Access
25 Citations
6,082 Views
11 Pages

Microbial Profile of the Ventriculum of Honey Bee (Apis mellifera ligustica Spinola, 1806) Fed with Veterinary Drugs, Dietary Supplements and Non-Protein Amino Acids

  • Giovanni Cilia,
  • Filippo Fratini,
  • Elena Tafi,
  • Barbara Turchi,
  • Simone Mancini,
  • Simona Sagona,
  • Antonio Nanetti,
  • Domenico Cerri and
  • Antonio Felicioli

The effects of veterinary drugs, dietary supplements and non-protein amino acids on the European honey bee (Apis mellifera ligustica Spinola, 1806) ventriculum microbial profile were investigated. Total viable aerobic bacteria, Enterobacteriaceae, st...

(This article belongs to the Special Issue Honey Bee Health)
  • Article
  • Open Access
11 Citations
5,596 Views
13 Pages

Comparative Genome Analysis of a Pathogenic Erysipelothrix rhusiopathiae Isolate WH13013 from Pig Reveals Potential Genes Involve in Bacterial Adaptions and Pathogenesis

  • Longsheng Yang,
  • Yongwei Zhu,
  • Zhong Peng,
  • Yi Ding,
  • Kai Jie,
  • Zijian Wang,
  • Ying Peng,
  • Xibiao Tang,
  • Xiangru Wang and
  • Chen Tan
  • + 1 author

Erysipelothrix rhusiopathiae is a common pathogen responsible for pig erysipelas. However, the molecular basis for the pathogenesis of E. rhusiopathiae remains to be elucidated. In this study, the complete genome sequence of the E. rhusiopathiae stra...

(This article belongs to the Section Veterinary Microbiology, Parasitology and Immunology)
  • Review
  • Open Access
121 Citations
13,713 Views
9 Pages

Heat stress compromises efficient poultry production by impairing growth performance and increasing mortality. Mechanisms to dissipate excess heat divert energy from efficient production. This includes increased energy expenditure for respiration, ox...

  • Article
  • Open Access
6 Citations
8,319 Views
8 Pages

Evaluation of Symmetric Dimethylarginine (SDMA) in Dogs with Acute Pancreatitis

  • Eleonora Gori,
  • Alessio Pierini,
  • Ilaria Lippi,
  • Valentina Meucci,
  • Francesca Perondi and
  • Veronica Marchetti

Symmetric dimethylarginine (SDMA) is considered an important biomarker of kidney dysfunction. The aims of the study were to evaluate SDMA in dogs with acute pancreatitis (AP) and its relationship with the presence of kidney injury and mortality. A co...

  • Article
  • Open Access
20 Citations
6,407 Views
12 Pages

Prevalence and Diversity of Avian Influenza Virus Hemagglutinin Sero-Subtypes in Poultry and Wild Birds in Bangladesh

  • Mohammad M. Hassan,
  • Mohamed E. El Zowalaty,
  • Ariful Islam,
  • Shahneaz A. Khan,
  • Md. K. Rahman,
  • Josef D. Järhult and
  • Md. A. Hoque

Highly pathogenic avian influenza H5 viruses have pandemic potential, cause significant economic losses and are of veterinary and public health concerns. This study aimed to investigate the distribution and diversity of hemagglutinin (HA) subtypes of...

  • Article
  • Open Access
7 Citations
6,659 Views
15 Pages

Immunohistochemical Studies of Cytokeratins and Differentiation Markers in Bovine Ocular Squamous Cell Carcinoma

  • Helena Vala,
  • Tânia Carvalho,
  • Carlos Pinto,
  • Maria A. Pereira,
  • João R. Mesquita,
  • Maria C. Peleteiro,
  • Lluís Ferrer and
  • Dolores Fondevila

Bovine Ocular Squamous Cell Carcinoma is considered the most common bovine tumour, causing significant economic losses, mainly by abattoir condemnations. To obtain a better insight into the genesis and neoplastic transformation, 19 samples collected...

(This article belongs to the Section Anatomy, Histology and Pathology)
  • Article
  • Open Access
20 Citations
5,185 Views
13 Pages

Chicken meat is a food of high nutritional quality; its production requires birds called broilers breeders and looking after all aspects that influence their reproductive capacity. An ongoing controversy exists among researchers related to the weight...

  • Article
  • Open Access
19 Citations
6,171 Views
18 Pages

Minimal Invasive Piezoelectric Osteotomy in Neurosurgery: Technic, Applications, and Clinical Outcomes of a Retrospective Case Series

  • Alberto Maria Crovace,
  • Sabino Luzzi,
  • Luca Lacitignola,
  • Gerardo Fatone,
  • Alice Giotta Lucifero,
  • Tomaso Vercellotti and
  • Antonio Crovace

Objective: To report the physical and technical principles, clinical applications, and outcomes of the minimal invasive piezoelectric osteotomy in a consecutive veterinary neurosurgical series. Methods: A series of 292 dogs and 32 cats underwent an o...

  • Communication
  • Open Access
11 Citations
6,703 Views
6 Pages

Hemangiosarcomas (HSA) are common neoplasms of dogs that often metastasize and are typically fatal. Recently it was demonstrated that thalidomide extends the survival time of dogs with HSA, potentially due to thalidomide-induced inhibition of vascula...

  • Communication
  • Open Access
16 Citations
5,578 Views
6 Pages

Cattle are susceptible to infection with multiple serovars of pathogenic leptospires, resulting in abortion, stillbirth, premature birth, reproductive failure and milk drop syndrome. Cattle also act as a reservoir host for L. borgpetersenii serovar H...

(This article belongs to the Section Veterinary Microbiology, Parasitology and Immunology)
  • Article
  • Open Access
20 Citations
7,128 Views
14 Pages

Efficacy of Live Attenuated Vaccine and Commercially Available Lectin against Avian Pathogenic E. coli Infection in Broiler Chickens

  • Ahmed I. Abd El-Mawgoud,
  • El-Shayma El-Nahass,
  • Salama A.S. Shany,
  • Azza A. EL-Sawah,
  • Al-Hussien M. Dahshan,
  • Soad A. Nasef and
  • Ahmed Ali

In this study, the protective efficacy of an E. coli live attenuated vaccine was compared to the preventive administration of lectin preparation before the challenge. Two hundred broiler chicks were divided into eight equal groups. The first group wa...

(This article belongs to the Section Veterinary Microbiology, Parasitology and Immunology)
  • Communication
  • Open Access
8 Citations
5,412 Views
9 Pages

Characterizing the Role of SMYD2 in Mammalian Embryogenesis—Future Directions

  • Dillon K. Jarrell,
  • Kelly N. Hassell,
  • Debbie C. Crans,
  • Shari Lanning and
  • Mark A. Brown

The SET and MYND domain-containing (SMYD) family of lysine methyltransferases are essential in several mammalian developmental pathways. Although predominantly expressed in the heart, the role of SMYD2 in heart development has yet to be fully elucida...

  • Review
  • Open Access
29 Citations
7,277 Views
12 Pages

Pneumoperitoneum in Veterinary Laparoscopy: A Review

  • Jacqueline Scott,
  • Ameet Singh and
  • Alexander Valverde

Objective: To review the effects of carbon dioxide pneumoperitoneum during laparoscopy, evaluate alternative techniques to establishing a working space and compare this to current recommendations in veterinary surgery. Study Design: Literature review...

  • Article
  • Open Access
7 Citations
6,045 Views
15 Pages

Evidence is accumulating that tumour development is driven by cancer stem cells (CSCs). In order to understand the presence and potential contribution of stem cells (SCs) as tumour-initiating cells in canine cutaneous tumours, we selected three putat...

(This article belongs to the Section Anatomy, Histology and Pathology)
  • Article
  • Open Access
4 Citations
7,120 Views
15 Pages

Using Manual and Computer-Based Text-Mining to Uncover Research Trends for Apis mellifera

  • Esmaeil Amiri,
  • Prashant Waiker,
  • Olav Rueppell and
  • Prashanti Manda

Honey bee research is believed to be influenced dramatically by colony collapse disorder (CCD) and the sequenced genome release in 2006, but this assertion has never been tested. By employing text-mining approaches, research trends were tested by ana...

(This article belongs to the Special Issue Honey Bee Health)
  • Article
  • Open Access
13 Citations
4,934 Views
11 Pages

Toxicity in Goats Exposed to Arsenic in the Region Lagunera, Northern Mexico

  • Natalia B. Ortega-Morales,
  • José A. Cueto-Wong,
  • Eutiquio Barrientos-Juárez,
  • Gonzalo García-Vargas,
  • Homero Salinas-González,
  • Alain Buendía Garcia and
  • Javier Morán-Martínez

The Region Lagunera, a region in northeast Mexico, is undergoing significant problems with the quality of its groundwater, which exceeds the permissible limits of contaminants and/or heavy metals stipulated in Mexican legislation. The present study e...

  • Article
  • Open Access
3 Citations
8,237 Views
13 Pages

In avian medicine, Doppler sonographic techniques are used to visualize and estimate blood flow in the heart. In the literature there is a lack of standardized studies of the use of color Doppler flow on healthy avian species. For this purpose, we ex...

  • Article
  • Open Access
14 Citations
7,466 Views
7 Pages

The Outcome and Economic Viability of Embryo Production Using IVF and SOV Techniques in the Wagyu Breed of Cattle

  • Fernanda L. Facioli,
  • Flávia De Marchi,
  • Mariana G. Marques,
  • Paulo R. P. Michelon,
  • Eraldo L. Zanella,
  • Kyle C. Caires,
  • Jerry J. Reeves and
  • Ricardo Zanella

The Japanese black cattle breed (Wagyu) has an improved metabolism, which allows them to have a higher marbling score when compared with other cattle breeds. However, this may affect other aspects of the animal’s physiology, including hormone secreti...

  • Article
  • Open Access
9 Citations
6,617 Views
11 Pages

Effects of Joint Lavage with Dimethylsulfoxide on LPS-Induced Synovitis in Horses—Clinical and Laboratorial Aspects

  • Eric Danilo Pauls Sotelo,
  • Cynthia Prado Vendruscolo,
  • Joice Fülber,
  • Sarah Raphaela Torquato Seidel,
  • Fernando Mosquera Jaramillo,
  • Fernanda Rodrigues Agreste,
  • Luís Cláudio Lopes Correia da Silva and
  • Raquel Yvonne Arantes Baccarin

30 April 2020

Several studies in human and equine medicine have produced controversial results regarding the role of dimethylsulfoxide (DMSO) as a therapeutic agent. This study aimed to evaluate the effect of joint lavage with different DMSO concentrations on biom...

  • Article
  • Open Access
49 Citations
8,050 Views
11 Pages

27 April 2020

Methicillin-resistant Staphylococcus aureus (MRSA) is a well-known pathogen with a serious impact on human and veterinary public health. To determine antibiotic resistance of MRSA in poultry, 4248 nasal swabs were collected from 840 poultry farms in...

(This article belongs to the Special Issue Resistant Staphylococci in Animals)
  • Article
  • Open Access
9 Citations
8,846 Views
12 Pages

Clinical and Pathological Data of 17 Non-Epithelial Pancreatic Tumors in Cats

  • Katrin Törner,
  • Marlies Staudacher,
  • Katja Steiger and
  • Heike Aupperle-Lellbach

27 April 2020

Tumors of mesenchymal origin are rarely reported in the pancreas. Therefore, this study characterized 17 feline non-epithelial pancreatic tumors, including clinical data, histopathology, and immunohistochemistry. Seventeen feline pancreatic tissue sa...

  • Review
  • Open Access
44 Citations
8,358 Views
12 Pages

A Review of the Public Health Challenges of Salmonella and Turtles

  • Hamid Reza Sodagari,
  • Ihab Habib,
  • Majedeh Pakzad Shahabi,
  • Narelle A. Dybing,
  • Penghao Wang and
  • Mieghan Bruce

27 April 2020

Non-typhoidal Salmonella serovars are recognized as zoonotic pathogens. Although human salmonellosis is frequently associated with ingestion of contaminated foods of animal origin, contact with animals may also be a significant source of Salmonella i...

(This article belongs to the Section Veterinary Microbiology, Parasitology and Immunology)
  • Article
  • Open Access
17 Citations
4,478 Views
10 Pages

Effect of Oral Administration of 1,3-1,6 β-Glucans in DWV Naturally Infected Newly Emerged Bees (Apis mellifera L.)

  • Antonio Felicioli,
  • Mario Forzan,
  • Simona Sagona,
  • Paola D’Agostino,
  • Diego Baido,
  • Baldassare Fronte and
  • Maurizio Mazzei

25 April 2020

Honeybee pathogens have an important role in honeybee colony mortality and colony losses; most of them are widely spread and necessitate worldwide solutions to contrast honeybee’s decline. Possible accepted solutions to cope with the spread of...

  • Article
  • Open Access
1 Citations
4,363 Views
8 Pages

In Vitro Inhibiting Effects of Three Fungal Species on Eggs of Donkey Gastrointestinal Strongyles

  • Michela Maestrini,
  • Simona Nardoni,
  • Francesca Mancianti,
  • Simone Mancini and
  • Stefania Perrucci

25 April 2020

Recently, donkeys have gained popularity mainly due to the use of donkey milk by the cosmetic industry and for human consumption. Gastrointestinal strongyles (GIS) are considered a potential cause of disease and reduced production in infected donkeys...

  • Article
  • Open Access
8 Citations
5,630 Views
15 Pages

23 April 2020

Neuroblastoma, the most common extracranial solid tumor in children, accounts for 15% of all pediatric cancer deaths. Pharmaceutical applications of S-Nitrosylation, which, under normal conditions is involved with a host of epigenetic and embryologic...

  • Article
  • Open Access
27 Citations
8,232 Views
8 Pages

22 April 2020

Veterinary medicine consists of virtually the same medical specialties as human medicine, with veterinarians performing similar roles as medical doctors, albeit with different species. Despite these similarities, anecdotally, some perceptions of vete...

(This article belongs to the Section Veterinary Education, Veterinary Communication and Animal Behavior)
  • Article
  • Open Access
14 Citations
5,710 Views
12 Pages

22 April 2020

Decades of selective breeding for commercial purposes have rendered the broiler chicken (Gallus gallus domesticus) highly susceptible to heat and cold stress. A multitude of studies have documented the effects of thermal manipulation (TM) on broiler...

  • Case Report
  • Open Access
3 Citations
6,746 Views
11 Pages

Atypical Multibacterial Granulomatous Myositis in a Horse: First Report in Italy

  • Claudia Rifici,
  • Anna-Rita Attili,
  • Davide De Biase,
  • Roselane Gonçalves dos Santos,
  • Núbia Seyffert,
  • Thiago Luiz De Paula Castro,
  • Henrique Cesar Pereira Figueiredo,
  • Carmelo Scaramozzino,
  • Stefano Reale and
  • Giuseppe Mazzullo
  • + 4 authors

21 April 2020

Infectious causes of myositis are reported relatively uncommonly in horses. Among them, bacterial causes include Streptococcus equi subsp. zooepidemicus, Actinobacillus equuli, Fusobacterium spp. Staphylococcus spp, and Corynebacterium pseudotubercul...

  • Article
  • Open Access
22 Citations
5,900 Views
12 Pages

Antimicrobial Resistance Profiles and Characterization of Escherichia coli Strains from Cases of Neonatal Diarrhea in Spanish Pig Farms

  • Anna Vidal,
  • Laia Aguirre,
  • Chiara Seminati,
  • Montse Tello,
  • Noelia Redondo,
  • Marga Martín and
  • Laila Darwich

21 April 2020

Escherichia coli is considered one of the most common agents associated with neonatal diarrhea in piglets. The aim of this work was to characterize the pathogenic and antimicrobial resistance (AMR) profiles of 122 E. coli strains isolated from pigs s...

(This article belongs to the Section Veterinary Microbiology, Parasitology and Immunology)
  • Article
  • Open Access
40 Citations
6,681 Views
13 Pages

16 April 2020

In this study, fresh seafood in retail markets was investigated for the antibiotic susceptibility patterns of the faecal indicator Escherichia coli and distribution of important β-lactamase encoding genes. E. coli were isolated from 50 (37 fish...

  • Review
  • Open Access
26 Citations
9,174 Views
25 Pages

Akkermansia and Microbial Degradation of Mucus in Cats and Dogs: Implications to the Growing Worldwide Epidemic of Pet Obesity

  • Jose F. Garcia-Mazcorro,
  • Yasushi Minamoto,
  • Jorge R. Kawas,
  • Jan S. Suchodolski and
  • Willem M. de Vos

15 April 2020

Akkermansia muciniphila is a mucin-degrading bacterium that has shown the potential to provide anti-inflammatory and anti-obesity effects in mouse and man. We here focus on companion animals, specifically cats and dogs, and evaluate the microbial deg...

(This article belongs to the Section Veterinary Microbiology, Parasitology and Immunology)
  • Article
  • Open Access
42 Citations
9,963 Views
9 Pages

A Clinical Investigation on Serum Amyloid A Concentration in Client-Owned Healthy and Diseased Cats in a Primary Care Animal Hospital

  • Masashi Yuki,
  • Reina Aoyama,
  • Masahiro Nakagawa,
  • Takashi Hirano,
  • Eiji Naitoh and
  • Daiki Kainuma

15 April 2020

Although measurement of serum amyloid A (SAA) concentration in client-owned cats has already been shown to be clinically useful, limited data are available on common diseases at primary care hospitals. In this study, we measured the SAA concentration...

  • Article
  • Open Access
34 Citations
5,112 Views
12 Pages

Clinical, Molecular and Serological Diagnosis of Canine Leishmaniosis: An Integrated Approach

  • Maria Paola Maurelli,
  • Antonio Bosco,
  • Valentina Foglia Manzillo,
  • Fabrizio Vitale,
  • Daniela Giaquinto,
  • Lavinia Ciuca,
  • Giuseppe Molinaro,
  • Giuseppe Cringoli,
  • Gaetano Oliva and
  • Manuela Gizzarelli
  • + 1 author

14 April 2020

Canine leishmaniosis (CanL) is caused by protozoans of the genus Leishmania and characterized by a broad spectrum of clinical signs in dogs. Early diagnosis is of great importance in order to perform an appropriate therapy and to prevent progression...

  • Communication
  • Open Access
8 Citations
4,297 Views
8 Pages

Effect of Intramuscular Medetomidine Administration on Tear Flow in Rats

  • Teppei Kanda,
  • Yuka Mizoguchi,
  • Kayo Furumoto,
  • Yuki Shimizu,
  • Noritaka Maeta and
  • Toshinori Furukawa

13 April 2020

Medetomidine has been reported to decrease tear flow significantly in dogs, cats, and pigs when used as a sedative or analgesic; however, there are no such reports when it comes to rats. The present study aimed to investigate the effect of medetomidi...

  • Article
  • Open Access
6 Citations
9,573 Views
13 Pages

Trauma-Associated Pulmonary Laceration in Dogs—A Cross Sectional Study of 364 Dogs

  • Giovanna Bertolini,
  • Chiara Briola,
  • Luca Angeloni,
  • Arianna Costa,
  • Paola Rocchi and
  • Marco Caldin

12 April 2020

In this study, we describe the computed tomography (CT) features of pulmonary laceration in a study population, which included 364 client-owned dogs that underwent CT examination for thoracic trauma, and compared the characteristics and outcomes of d...

  • Article
  • Open Access
32 Citations
4,143 Views
8 Pages

Twenty-four Awassi lambs were randomly divided into two dietary treatments to assess the influence of black cumin meal (BCM; Nigella sativa L.) feeding on growth performance. Diets were no BCM (CON) or 150 g BCM/kg DM (BCM150)). Lambs were fed the ex...

  • Article
  • Open Access
8 Citations
5,560 Views
8 Pages

Assessment of Intra- and Inter-observer Measurement Variability in a Radiographic Metacarpophalangeal Joint Osteophytosis Scoring System for the Horse

  • Luca Lacitignola,
  • Annarita Imperante,
  • Francesco Staffieri,
  • Rocco De Siena,
  • Pasquale De Luca,
  • Arianna Muci and
  • Antonio Crovace

The study evaluated the intra- and inter-observer measurement variability of an osteophytosis metacarpophalangeal joint scoring system. Ten (n = 10) dorso/palmar, latero/medial, and oblique views of equine metacarpophalangeal joints affected by osteo...

  • Review
  • Open Access
22 Citations
30,288 Views
14 Pages

Impact of Nutritional Supplementation on Canine Dermatological Disorders

  • Andrea Marchegiani,
  • Alessandro Fruganti,
  • Andrea Spaterna,
  • Elena Dalle Vedove,
  • Benedetta Bachetti,
  • Marcella Massimini,
  • Francesco Di Pierro,
  • Alessandra Gavazza and
  • Matteo Cerquetella

Nutritional supplements, also known as complementary feeds, are products administered with the aim of furnishing health benefits, regardless of nutritional needs. They have been used since ancient times in veterinary dermatology, and a number of stud...

  • Case Report
  • Open Access
10 Citations
8,558 Views
6 Pages

Sebaceous adenitis and concurrent meibomian gland dysfunction (MGD) were diagnosed in a two-year-old mongrel dog presenting with hypotrichosis, exfoliative dermatitis and blepharitis. Diagnosis of sebaceous adenitis was based on history, clinical sig...

  • Article
  • Open Access
34 Citations
7,538 Views
10 Pages

Molecular Detection of Multidrug Resistant Staphylococcus aureus Isolated from Bovine Mastitis Milk in Bangladesh

  • Md. Salauddin,
  • Mir Rowshan Akter,
  • Md. Khaled Hossain,
  • K. H. M. Nazmul Hussain Nazir,
  • Ayman Noreddin and
  • Mohamed E. El Zowalaty

30 March 2020

The current study was conducted to isolate and identify multidrug-resistant Staphylococcus aureus (MDR-SA) from mastitis milk samples and to determine their antimicrobial susceptibility pattern. A total of 48 bovine mastitis (BM) milk samples were co...

  • Article
  • Open Access
8 Citations
5,882 Views
19 Pages

25 March 2020

Computed tomography angiography (CTA) and biochemical parameters cannot specify liver pathologies in dogs with congenital portosystemic shunts (CPSS) that are easily determined by invasive histopathology. This study aims to assess the possibility of...

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Vet. Sci. - ISSN 2306-7381