2026 August - 109 articles
Addressing the current issues of the uncertain primary frequency bands and the difficulty in directly measuring the spectral characteristics of neural electromagnetic signals transmitted within nerve fibers, this study investigates the spectral and t...
Time-of-flight magnetic resonance angiography (TOF-MRA) is widely used for noninvasive visualization of arterial anatomy, but extracting hemodynamics like blood velocity typically requires supplementary phase-contrast scans, tagging or multi-TE image...
Background: Paclitaxel is a cornerstone chemotherapeutic agent widely used in breast cancer treatment, primarily through the stabilization of microtubule dynamics. Beyond its canonical tubulin-targeting activity, increasing evidence suggests that pac...
We develop a reaction–diffusion–chemotaxis model for spatial tumour–immune–chemokine dynamics that couples logistic tumour growth, immune-mediated killing, chemokine-dependent immune recruitment, chemotactic migration, and sig...
Background: Predicting recurrence after liver transplantation (LT) for hepatocellular carcinoma (HCC) remains important for post-transplant risk stratification and surveillance planning. The Milan criteria discriminate only moderately and some machin...
Vocal rise time (VRT) acoustically measures from when vocal cord vibration begins to when phonation achieves a peak steady state. This acoustic-based study examines manual and automatic VRT measurements based on different vowel onset recordings (e.g....
Individuals with transtibial amputation have impaired postural control due to limited ankle function. Conventional energy-storing-and-return (ESAR) prosthetic feet mainly support sagittal-plane mechanics and provide limited frontal-plane adaptability...
Skeletal-anchored mesial sliders are increasingly used for molar mesialization, yet their mechanical behavior has not been compared under standardized conditions. This in vitro pilot study evaluated four slider designs (BENEfit® Beneslider [BB],...
Vascularized tumor organoid and tumor-on-chip models are increasingly used to examine treatment response, yet a weak therapeutic effect does not by itself identify the failed transport or biological step. Reduced efficacy may result from inadequate d...
A clinical observation of a previously asymptomatic native knee developing a relevant coronal alignment change after total hip arthroplasty (THA) motivated this research. This raised the question of whether the native knee morphology could influence...
The rapid growth of multimodal neuroimaging research has produced fragmented literature that limits systematic characterization of cross-modal relationships and disease-specific knowledge structures. To address this, we constructed a multimodal neuro...
Purpose: To compare concordance of corneal tomographic measurements obtained using Anterion versus Pentacam HR. Setting: Outpatient ophthalmology clinic. Design: Retrospective cross-sectional study. Methods: Eyes without corneal abnormalities underwe...
The accurate evaluation of gastrointestinal (GI) diseases such as celiac disease (CeD) relies on the assessment of villous architecture, yet progress in imaging-based diagnostics, particularly video capsule endoscopy (VCE), is constrained by the abse...
Osteonecrosis of the femoral head (ONFH) is a progressive and potentially disabling condition caused by compromised blood supply to the femoral head, leading to bone necrosis and collapse. Early diagnosis is essential to enable joint-preserving inter...
Three-dimensional facial scanning is an important tool in reconstructive surgery and burn medicine for objective documentation, treatment planning, and fabrication of patient-specific devices. While professional structured-light scanners provide high...
Static pedobarometry is widely used to assess plantar pressure distribution and postural control; however, its clinical interpretation depends on measurement repeatability and reliability. The aim of our article is to evaluate the repeatability of pl...
The growing demand for high-quality plasmid DNA (pDNA) in cell and gene therapy, including chimeric antigen receptor T-cell therapy (CAR-T) manufacturing, is constrained by the limited availability of transfection-grade plasmids. This study describes...
Accurate morphological analysis of blood smears is vital for hematological diagnosis, yet manual examination is labor-intensive and subjective. While deep learning offers automation, its black-box nature and computational demands often hinder clinica...
Background/Objectives: Tissue fold artifacts observed in hematoxylin-eosin (H&E)- stained preparations used in histology education can complicate the assessment of normal tissue architecture and affect students’ accurate interpretation of m...
Background: The ASA Physical Status (ASA-PS) classification and the Charlson Comorbidity Index (CCI) are common pre-operative scoring tools. Language models could automate structured pre-operative scoring, but direct comparisons require paired infere...
Background: Facial nerve regeneration across segmental defects remains challenging despite advances in nerve guidance conduits. Tissue engineering strategies that combine biomaterial scaffolds with bioactive and cellular components may enhance functi...
Porous Ti-6Al-4V lattice implants combine high specific strength, osseointegrative porosity, and compatibility with additive manufacturing, but conventional stiffness tuning through porosity, pore size, or unit-cell topology compromises biological po...
Whether arch-specific anatomical configuration affects early peri-implant bone behavior in monolithic zirconia full-arch prostheses is unclear. This prospective cohort study evaluated 40 edentulous patients with 49 monolithic zirconia full-arch prost...
Multimodal large language models are increasingly used for dermatologic queries, but whether Fitzpatrick skin type (FST) labels affect diagnostic accuracy is unknown. We evaluated 656 biopsy-confirmed photographs from the Diverse Dermatology Images (...
Lung cancer arises from mutations in lung cells, disrupting their normal growth cycle and leading to uncontrolled cell division. These rapidly dividing cells lose function and fail to form healthy lung tissue. Several factors contribute to the diffic...
Background: Manual bag-valve ventilation is a fundamental intervention in prehospital and emergency care but remains highly operator-related and frequently associated with inappropriate tidal volume delivery. Excessive or insufficient ventilation may...
Early identification of COVID-19 patients requiring intensive care is critical for improving treatment prioritization, supporting clinical decision-making, and managing limited hospital resources. While structured electronic health record (EHR) data...
Artificial intelligence and bioengineering have developed along different historical trajectories, yet their areas of interest have progressively converged [...]
Background: Neurodynamic techniques are commonly used to improve neural mobility and musculoskeletal function, but their effects on muscle mechanical properties remain unclear. This study investigated the acute effects of femoral nerve slider, femora...
Biodegradable magnesium (Mg)-based implants represent a paradigm shift in orthopedic biomaterials, offering temporary mechanical support, inherent osteogenic bioactivity, and elimination of hardware removal surgery. These properties are particularly...
(1) Background: To compare tube resistance among glaucoma drainage devices (GDDs) with different tube geometries under various intraluminal polypropylene (PP) thread conditions and assess agreement between measured and formula-derived pressure–...
Background: Individuals with spinal cord injury (SCI) frequently experience chronic pain, trunk instability, and respiratory dysfunction. This pilot trial investigated the synergistic effects of a combined neuro-orthotic approach (thoracolumbosacral...
Accurate gait event detection using inertial measurement units (IMUs) is essential for temporal gait analysis, but frame-level detection is challenged by sparse initial contact (IC) and foot-off (FO) events. This study evaluated recurrent neural netw...
Imaging underpins the diagnosis and structural staging of osteonecrosis of the femoral head (ONFH) but does not directly quantify functional impairment during weight-bearing walking. We developed a subject-level ONFH classification framework using mu...
Contemporary intensive care operates in an environment with high-complexity cases, large volumes of information, and vast physiological, biological, and therapeutic data, collected from laboratory results, investigations, and therapies for organ supp...
The Internet of Medical Things (IoMT) is a promising technology for enabling smart and efficient healthcare systems through continuous physiological monitoring, early anomaly detection, and proactive patient management. However, IoMT sensors are vuln...
Human skin tone is an important consideration in pulse oximetry and evaluating skin health conditions. Various tools are available to measure skin tone, including visual scales, palette based estimations, and optical sensor based devices. The objecti...
Aerosol jet printing, AJP, has emerged as a versatile direct ink writing technology enabling high-resolution, non-contact patterning of diverse biomaterials across a broad viscosity range. This capability facilitates the fabrication of complex micro-...
Introduction: Voice-based digital biomarkers have emerged as a promising approach for distinguishing individuals with neurodegenerative disorders, particularly Parkinson’s disease (PD), from healthy subjects (HS). With the increasing availabili...
Sports-related oro-dento-facial trauma is a major clinical and socioeconomic burden, with oro-dento-facial injuries affecting approximately 30–40% of athletes. Mouthguards are widely recommended as primary protective devices, yet the comparativ...
A prosthetic vascular graft is an important vascular conduit used for end-to-end anastomosis; however, optimizing pore morphology to improve local hemodynamic performance remains a significant challenge. The purpose of this study was to investigate t...
Promptable medical segmentation models can be sensitive to small targets, weak boundaries, heterogeneous texture, and inaccurate user prompts. We propose HBF-BCER, a prompt-preserving adaptation of the SAM ViT-B architecture for medical image segment...
Footwear geometry plays an important role in determining mechanical performance, plantar load distribution, comfort, and foot stability during gait. Understanding how constructive design parameters influence foot biomechanics is essential for develop...
Vision-language models (VLMs) are increasingly evaluated for retinal image interpretation, but end-task discrimination does not establish whether a prediction depends on the optical coherence tomography (OCT) image. We evaluated RetinaVLM, LLaVA-Med,...
Mouse models have been indispensable for defining the mechanisms of atherosclerosis, yet no single model reproduces the full spectrum of human disease. This review provides a practical framework for selecting mouse models according to the biological...
Conventional spinal braces often suffer from poor fit and low breathability, with most 3D-printing research focusing on scoliosis rather than general support. This study evaluated the biomechanical performance and range of motion (ROM) restriction of...
This exploratory in vivo study investigated the therapeutic potential of intradiscal platelet-rich plasma (PRP) in a rat model of degenerative disc disease (DDD) using quantitative 4.7-T MRI and histologic correlation. Eight female Sprague-Dawley rat...
Osteoarthritis is an irreversible degenerative joint disease driven by sustained NF-κB-mediated inflammatory responses, and conventional intra-articular hyaluronic acid or small-molecule NF-κB inhibitors cannot achieve targeted on-demand...
Sports teams are constantly seeking advanced technologies to gain a competitive edge by enhancing athletic performance, accelerating recovery, and minimizing injury risk. Sweat serves as a readily accessible biofluid which enables non-invasive measur...
Alveolar bone resorption after tooth extraction complicates subsequent dental implant placement. OsteoBiol® GTO® (Tecnoss®, Giaveno, Italy) is an innovative pre-hydrated heterologous collagenated bone mix blended with a thermosensitive co...
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