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Children, Volume 10, Issue 10

2023 October - 139 articles

Cover Story: In this selected cover story, Körner et al. present striking immune dysregulations in children and adolescents at a dedicated specialty clinic for Post COVID-19 Condition (PCC) and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The reported patients exhibited elevated IgE levels and sensitizations to aeroallergens regardless of PCC severity. Patients with concomitant ME/CFS showed significantly elevated IgG subclasses IgG3 and IgG4. The authors discuss atopic disorders and an exaggerated immune response as potential risk factors for PCC in the context of neuropsychological and pneumological findings from comprehensive clinical and molecular investigations. This study draws necessary attention to early-onset immune dysregulation in the manifestation and severity of pediatric multi-system post-viral disease that may be relevant for other present and future pathogens. View this paper
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Articles (139)

  • Article
  • Open Access
2 Citations
1,823 Views
11 Pages

Health-Related Quality of Life and Mental Health of Children with Embryonal Abdominal Tumors

  • Paulina Behrendt,
  • Michael Boettcher,
  • Kira Tabea Zierke,
  • Safiullah Najem,
  • Holger Zapf,
  • Konrad Reinshagen,
  • Wilhelm Wößmann and
  • Johannes Boettcher

23 October 2023

(1) Background: Embryonal abdominal tumors are one of the most common entities of solid childhood cancer. The present study investigates the Health-Related Quality of Life (HRQoL) and the mental health of children to obtain a comprehensive picture of...

  • Article
  • Open Access
1,883 Views
22 Pages

23 October 2023

Williams Syndrome (WS) involves high rates of psychopathology across the lifespan. However, little is known about the early, longitudinal trajectory of internalising/externalising symptoms or the association between these and the family environment i...

  • Article
  • Open Access
18 Citations
7,465 Views
13 Pages

23 October 2023

Most research on the impact of maternal depressive symptoms on child development is conducted during the first year postpartum. Findings on long-term effects of maternal depression are still contradictory and underexplored. The present study investig...

  • Article
  • Open Access
7 Citations
4,017 Views
13 Pages

What Components of Working Memory Are Impaired in Children with Reading and/or Mathematics Difficulties?

  • Rui Chen,
  • George K. Georgiou,
  • Peng Peng,
  • Yuanyuan Li,
  • Beilei Li,
  • Jiali Wang and
  • Sha Tao

23 October 2023

Both reading difficulties (RD) and mathematics difficulties (MD) are common neurodevelopmental disorders. The co-occurrence of RD and MD, known as comorbid RDMD, is estimated to range between 21% and 45% of children with learning disabilities. Defici...

  • Article
  • Open Access
1 Citations
2,540 Views
10 Pages

Transphyseal Humeral Separations: An Often-Missed Fracture

  • Arun R. Hariharan,
  • Hans K. Nugraha,
  • Christine A. Ho,
  • Andrea Bauer,
  • Charles T. Mehlman,
  • Paul D. Sponseller,
  • Nathan N. O’Hara and
  • Joshua M. Abzug

23 October 2023

Background: Transphyseal humeral separations (TPHS) are rare injuries often associated with non-accidental trauma, necessitating accurate diagnosis. This study aims to assess the accuracy of diagnosis of TPHS. Methods: A retrospective review was cond...

  • Article
  • Open Access
5 Citations
2,754 Views
10 Pages

Cutaneous, Cranial, and Skeletal Defects in Children and Adults with Focal Dermal Hypoplasia

  • Ali Al Kaissi,
  • Sergey Ryabykh,
  • Vladimir Kenis,
  • Farid Ben Chehida,
  • Hamza Al Kaissi,
  • Susanne Gerit Kircher and
  • Franz Grill

22 October 2023

Background: The diagnostic process for children and adults manifesting a constellation of ectodermal abnormalities requires a conscientious and highly structured process. Material and Methods: Six girls (aged 6-month–8 years) and two older girl...

  • Article
  • Open Access
1 Citations
2,764 Views
12 Pages

22 October 2023

(1) Background: With shifts in daily dietary habits, concerns have arisen regarding potential impacts on metabolic health. This study sought to investigate the interplay between nutrient intake and its effects on the anthropometric and inflammatory p...

  • Article
  • Open Access
1 Citations
2,200 Views
12 Pages

Care Issues in Patients with Rett Syndrome: A Parental Perspective

  • Claudio Cherchi,
  • Elena Chiappini,
  • Maria Beatrice Chiarini Testa,
  • Paolo Banfi,
  • Edvige Veneselli and
  • Renato Cutrera

21 October 2023

Background: The purpose of this study is to better understand the way caregivers of patients with Rett syndrome perceive the quality of the health care services they receive and identify its main shortcomings. Methods: A survey was distributed to all...

  • Perspective
  • Open Access
6 Citations
2,740 Views
10 Pages

Opportunities and Challenges of Prognostic Models for Extremely Preterm Infants

  • Angret de Boer,
  • Pauline E. van Beek,
  • Peter Andriessen,
  • Floris Groenendaal,
  • Marije Hogeveen,
  • Julia S. Meijer,
  • Sylvia A. Obermann-Borst,
  • Wes Onland,
  • Liesbeth (H. C. J.) Scheepers and
  • Rosa Geurtzen
  • + 3 authors

21 October 2023

Predicting the short- and long-term outcomes of extremely preterm infants remains a challenge. Multivariable prognostic models might be valuable tools for clinicians, parents, and policymakers for providing accurate outcome estimates. In this perspec...

  • Article
  • Open Access
2 Citations
2,415 Views
17 Pages

Association between the Carbohydrate Quality Index (CQI) and Nutritional Adequacy in a Pediatric Cohort: The SENDO Project

  • Elise Fabios,
  • Miguel Ángel Martínez-González,
  • Lorena García-Blanco,
  • Víctor de la O,
  • Susana Santiago,
  • Itziar Zazpe and
  • Nerea Martín-Calvo

20 October 2023

Suboptimal micronutrient intake in children remains a public health concern around the world. This study examined the relationship between a previously defined dietary carbohydrate quality index (CQI) and the risk of micronutrient intake inadequacy i...

  • Systematic Review
  • Open Access
6 Citations
4,594 Views
10 Pages

20 October 2023

Probiotics are known to decrease incidences of necrotising enterocolitis, feeding intolerance, late-onset sepsis, and mortality in preterm infants. Administering an adequate dose is important for optimizing the benefits and safety of probiotics. We c...

  • Systematic Review
  • Open Access
3 Citations
2,320 Views
12 Pages

Characterization of Non-Food Foreign Bodies Aspirated by Children: A Systematic Review of the Literature

  • Giulia Lorenzoni,
  • Marco Vertuani,
  • Valeria Basso,
  • Paola Rescigno,
  • Honoria Ocagli and
  • Dario Gregori

20 October 2023

Background. Foreign Body Aspiration (FBA) represents a leading cause of death among unintentional injuries in children less than one year of age. This study reviewed case reports and case series reporting non-food FBA in children to characterize aspi...

  • Article
  • Open Access
3 Citations
4,476 Views
11 Pages

Evolution of the Terminal Plane from Deciduous to Mixed Dentition

  • María Eugenia Cabrera-Domínguez,
  • Antonia Domínguez-Reyes and
  • Antonio F. Galan-Gonzalez

20 October 2023

(1) Introduction: Correct development and growth of the dental arches and occlusion in the deciduous dentition is crucial for physiological occlusion in the permanent dentition. The present study evaluates the evolution of the terminal plane and cani...

  • Review
  • Open Access
2 Citations
2,920 Views
10 Pages

Sleep Respiratory Disorders in Children and Adolescents with Cystic Fibrosis and Primary Ciliary Dyskinesia

  • Maria Papale,
  • Sara Manti,
  • Santiago Presti,
  • Federico Mollica,
  • Giuseppe F. Parisi and
  • Salvatore Leonardi

20 October 2023

Cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) are genetic respiratory diseases featured by chronic upper and lower airway inflammation and infection, mainly due to impaired mucociliary clearance due to genetic mutations. Sleep is crucial...

  • Article
  • Open Access
1 Citations
1,979 Views
16 Pages

20 October 2023

(1) Aim: The aim of the study was to develop and analyze the psychometric properties of a hospital perception scale for healthy children aged 8 to 10 years. (2) Methods: A methodological design was employed. The scale’s validity was investigate...

  • Article
  • Open Access
1,965 Views
15 Pages

Does the Modality of Dental Treatment Affect the Treatment Prognosis and the Necessity of Re-Treatments?

  • İrem Bağ,
  • Seçil Çalışkan,
  • Alaz Oya Erenel,
  • Kübra Nur Sevimli and
  • Merve Candan

19 October 2023

Background: The utilization of evidence-based approaches is crucial to achieving long-term positive outcomes for treatment performed chairside or under general anesthesia. The study aimed to evaluate if treatment modality (at the chairside or under g...

  • Article
  • Open Access
2 Citations
3,009 Views
11 Pages

19 October 2023

Background: Past research has shown that perfectionistic strivings (PS) and perfectionistic concerns (PC) in the parenting domain are associated with an increase in parental burnout (PB), and that PB causally increases violence towards one’s of...

  • Article
  • Open Access
2 Citations
2,261 Views
15 Pages

Characteristics and Risk Factors Associated with SARS-CoV-2 Pneumonias in Hospitalized Pediatric Patients: A Pilot Study

  • María Hernández-García,
  • Claudia Solito,
  • Alba Pavón Ortiz,
  • Noelia Arguedas Casamayor,
  • Maria Melé-Casas,
  • Gemma Pons-Tomàs,
  • Mariona F. de Sevilla,
  • Rosa Pino,
  • Cristian Launes and
  • Juan José García-García
  • + 3 authors

19 October 2023

SARS-CoV-2 pneumonia in children has a lower incidence and severity compared to adults. Risk factors are adolescence and comorbidities. Our aims were to describe the characteristics of children admitted with SARS-CoV-2 pneumonia, identify risk factor...

  • Article
  • Open Access
7 Citations
3,138 Views
14 Pages

Sleep Stage Transitions and Sleep-Dependent Memory Consolidation in Children with Narcolepsy–Cataplexy

  • Katia Gagnon,
  • Amandine E. Rey,
  • Anne Guignard-Perret,
  • Aurore Guyon,
  • Eve Reynaud,
  • Vania Herbillon,
  • Jean-Marc Lina,
  • Julie Carrier,
  • Patricia Franco and
  • Stéphanie Mazza

18 October 2023

Electroencephalographic sleep stage transitions and altered first REM sleep period transitions have been identified as biomarkers of type 1 narcolepsy in adults, but not in children. Studies on memory complaints in narcolepsy have not yet investigate...

  • Case Report
  • Open Access
5 Citations
3,491 Views
9 Pages

Phenotype of Idiopathic Infantile Hypercalcemia Associated with the Heterozygous Pathogenic Variant of SLC34A1 and CYP24A1

  • Teofana Otilia Bizerea-Moga,
  • Flavia Chisavu,
  • Cristina Ilies,
  • Orsolya Olah,
  • Otilia Marginean,
  • Mihai Gafencu,
  • Gabriela Doros and
  • Ramona Stroescu

17 October 2023

Idiopathic infantile hypercalcemia (IIH) is a rare genetic disease, also called hypersensitivity to vitamin D3. The molecular heterogeneity allows for the differentiation between the two forms; IIH type 1 caused by CYP24A1 genetic variants and IIH ty...

  • Case Report
  • Open Access
2,042 Views
7 Pages

17 October 2023

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disorder, estimated to affect 1 in 1000 people. It displays a high level of variability in terms of onset and severity among affected individuals within the sam...

  • Review
  • Open Access
20 Citations
11,006 Views
21 Pages

“Light” on Phototherapy—Complications and Strategies for Shortening Its Duration, A Review of the Literature

  • Irit Shoris,
  • Ayala Gover,
  • Arina Toropine,
  • Adir Iofe,
  • Rasha Zoabi-Safadi,
  • Svetlana Tsuprun and
  • Arieh Riskin

17 October 2023

Neonatal hyperbilirubinemia is an extremely common metabolic complication of the neonatal period which may be associated with bilirubin encephalopathy and even death. Adverse neurological consequences are preventable if a timely diagnosis and treatme...

  • Case Report
  • Open Access
3 Citations
2,109 Views
12 Pages

17 October 2023

Inflammatory bowel disease (IBD) is the term given to a heterogeneous group of chronic inflammatory diseases of the gastrointestinal tract (GI). These include ulcerative colitis (UC), where the inflammatory process involves only the intestinal mucosa...

  • Review
  • Open Access
6 Citations
3,775 Views
11 Pages

Why Is There Always a Remnant Rib Hump Deformity after Spinal Operations in Idiopathic Scoliosis: Aetiological Implications and Recognition of the Proper Rib Level for Costoplasty

  • Theodoros B. Grivas,
  • Elias Vasiliadis,
  • George Vynichakis,
  • Michail Chandrinos,
  • Konstantinos Athanasopoulos and
  • Paschalis Christodoulides

17 October 2023

The aim of this report is to review the literature dealing with the postoperative correction of rib hump (RH) after spinal operations for adolescent idiopathic scoliosis (AIS) and its aetiological implications of hump postoperative fate for IS. Recom...

  • Article
  • Open Access
7 Citations
2,696 Views
13 Pages

Application of Next-Generation Sequencing to Enterobacter Hormaechei Subspecies Analysis during a Neonatal Intensive Care Unit Outbreak

  • Patrick Morhart,
  • Roman G. Gerlach,
  • Caroline Kunz,
  • Jürgen Held,
  • Giuseppe Valenza,
  • Joachim Wölfle,
  • Heiko Reutter,
  • Gregor J. Hanslik and
  • Fabian B. Fahlbusch

16 October 2023

Introduction: The Enterobacter cloacae complex (ECC) species are potential neonatal pathogens, and ECC strains are among the most commonly encountered Enterobacter spp. associated with nosocomial bloodstream infections. Outbreaks caused by ECC can le...

  • Article
  • Open Access
12 Citations
3,607 Views
12 Pages

16 October 2023

Background: The prognosis of orthodontic treatment for a patient with impacted canine teeth can be affected by many factors and understanding some of the characteristics of impacted teeth can increase the effectiveness and reduce the duration of trea...

  • Article
  • Open Access
9 Citations
2,449 Views
15 Pages

“Are You a Boy or a Girl?”—A Missing Response Analysis

  • Andreas Heinz,
  • András Költő,
  • Ashley B. Taylor and
  • Ace Chan

16 October 2023

Many adolescent health surveys ask if respondents are male or female. Non-response may be due to fear of de-anonymisation or being a gender-nonconforming youth. The present study investigates the frequency of non-response and its potential reasons. T...

  • Article
  • Open Access
5 Citations
2,887 Views
16 Pages

Identification of Metabolomic Signatures for Ischemic Hypoxic Encephalopathy Using a Neonatal Rat Model

  • Yulia Shevtsova,
  • Chupalav Eldarov,
  • Natalia Starodubtseva,
  • Kirill Goryunov,
  • Vitaliy Chagovets,
  • Oleg Ionov,
  • Egor Plotnikov and
  • Denis Silachev

16 October 2023

A study was performed to determine early metabolomic markers of ischemic hypoxic encephalopathy (HIE) using a Rice–Vannucci model for newborn rats. Dried blood spots from 7-day-old male and female rat pups, including 10 HIE-affected animals and...

  • Article
  • Open Access
1 Citations
2,401 Views
13 Pages

Focus Groups to Inform User-Centered Development of an eHealth Sleep Intervention for Adolescents: Perspectives of Youth with Insomnia Symptoms, with and without Pain

  • Michelle Tougas,
  • Gabrielle Rigney,
  • Christine Chambers,
  • Isabel Smith,
  • Joshua Mugford,
  • Laura Keeler,
  • Malgorzata Rajda and
  • Penny Corkum

16 October 2023

Introduction: Adolescence is a developmental stage that often coincides with increasing sleep problems. Focus groups were conducted to inform development of an adolescent eHealth sleep intervention by exploring opinions about (1) healthy sleep practi...

  • Article
  • Open Access
12 Citations
5,972 Views
13 Pages

16 October 2023

The purpose of this study was to analyse the effect of emotional intelligence between the perception of autonomy support from physical education teachers and self-esteem (positive and negative) in secondary-school physical education students. The stu...

  • Article
  • Open Access
19 Citations
6,920 Views
14 Pages

Body Image and Psychological Impact of Dental Appearance in Adolescents with Malocclusion: A Preliminary Exploratory Study

  • Federica Sicari,
  • Emanuele Maria Merlo,
  • Giulia Gentile,
  • Riccardo Nucera,
  • Marco Portelli,
  • Salvatore Settineri,
  • Liam Alexander MacKenzie Myles and
  • Angela Militi

16 October 2023

Background: Body image and psychosocial functioning represent central challenges during adolescence and early adulthood. Malocclusion, defined as an irregularity in the alignment of the teeth, is known to negatively influence psychological outcomes....

  • Article
  • Open Access
1,946 Views
11 Pages

Parental Perception of Remote Education in Pandemic: An Analysis Based on Children’s Cognitive Performance

  • Jasmin Bonilla-Santos,
  • Alfredis González-Hernández,
  • Dorian Yisela Cala-Martinez,
  • Duvan Fernando Gómez Morales and
  • Tatiana Padilla-García

16 October 2023

The COVID-19 pandemic significantly changed patterns of human interaction, including in the educational sector, which was forced to transform relationships among students, families, and the academic community. The present study sought to establish th...

  • Article
  • Open Access
4 Citations
3,231 Views
16 Pages

Understanding School Anxiety in Italian Adolescence through an Artificial Neural Network: Influence of Social Skills and Coping Strategies

  • Francisco Manuel Morales-Rodríguez,
  • Juan Pedro Martínez-Ramón,
  • Manuel Alejandro Narváez Peláez and
  • Catalda Corvasce

14 October 2023

School anxiety depends on multiple factors that occur directly or indirectly in the teaching–learning process, such as going to the blackboard in class or reporting low grades at home. Other factors that influence school climate are social skil...

  • Article
  • Open Access
4 Citations
3,261 Views
8 Pages

Nutritional Status of Children with Newly Diagnosed Food Allergies

  • Martyna Jasielska,
  • Anna Buczyńska,
  • Piotr Adamczyk and
  • Urszula Grzybowska-Chlebowczyk

14 October 2023

Background: Most published pediatric guidelines on food allergy highlight the importance of nutritional counseling and dietary adequacy to avoid either growth retardation or nutritional deficiencies. The aim of the study was an assessment of the nutr...

  • Review
  • Open Access
4 Citations
6,479 Views
10 Pages

Breast and Formula Milk and Early Puberty Onset

  • Valeria Calcaterra,
  • Hellas Cena,
  • Francesca Sottotetti,
  • Virginia Rossi,
  • Federica Loperfido and
  • Gianvincenzo Zuccotti

14 October 2023

Nutrients have an enormous impact on many hormonal systems and aspects of health, and nutrition status is a crucial regulator of growth and pubertal development in children and adolescents. In this narrative review, we explore the connection between...

  • Systematic Review
  • Open Access
3 Citations
5,304 Views
19 Pages

A Systematic Review of Clinical Practice Guidelines for Neonatal Abstinence Syndrome

  • Zoe Wei,
  • Yasmin Gilbert,
  • Arabhi Thananjeyan,
  • James Cope,
  • Rachael L. Morton,
  • Annie Li,
  • Cecile T. Pham,
  • Meredith Ward and
  • Ju Lee Oei

13 October 2023

Background: The prevalence of neonatal abstinence syndrome is increasing, but the number and quality of clinical practice guidelines available are unknown. This systematic review aimed to identify, appraise and evaluate clinical practice guidelines f...

  • Article
  • Open Access
6 Citations
2,692 Views
12 Pages

Clinical and Genetic Characterization of Patients with Primary Ciliary Dyskinesia in Southwest Saudi Arabia: A Cross Sectional Study

  • Ali Alsuheel Asseri,
  • Ayed A. Shati,
  • Ibrahim A. Asiri,
  • Reem H. Aldosari,
  • Hassan A. Al-Amri,
  • Mohammed Alshahrani,
  • Badriah G. Al-Asmari and
  • Haleimah Alalkami

13 October 2023

Background: Primary ciliary dyskinesia (PCD, MIM 244400) is an inherited ciliopathy disorder characterized by recurrent sinopulmonary infections, subfertility, and laterality defects. The true incidence of PCD in Saudi Arabia is not known, but it is...

  • Review
  • Open Access
5 Citations
4,310 Views
16 Pages

Accelerated Aging and the Life Course of Individuals Born Preterm

  • Audrey Bousquet,
  • Keia Sanderson,
  • T. Michael O’Shea and
  • Rebecca C. Fry

13 October 2023

Individuals born preterm have shorter lifespans and elevated rates of chronic illness that contribute to mortality risk when compared to individuals born at term. Emerging evidence suggests that individuals born preterm or of low birthweight also exh...

  • Article
  • Open Access
5 Citations
2,577 Views
14 Pages

Barriers and Facilitators to the Implementation of the Early-Onset Sepsis Calculator: A Multicenter Survey Study

  • Liesanne E. J. van Veen,
  • Bo M. van der Weijden,
  • Leti van Bodegom-Vos,
  • Jeroen Hol,
  • Douwe H. Visser,
  • Niek B. Achten and
  • Frans B. Plötz

12 October 2023

Prior studies demonstrated the neonatal early-onset sepsis (EOS) calculator’s potential in drastically reducing antibiotic prescriptions, and its international adoption is increasing rapidly. To optimize the EOS calculator’s impact, succe...

  • Article
  • Open Access
3 Citations
3,004 Views
13 Pages

12 October 2023

(1) Background: This implementation study reports on the results of the mobile vaccination teams’ (MVTs) activities during the first two years of the COVID-19 pandemic in Kyrgyzstan, when other vaccination services were disrupted. (2) Methods:...

  • Article
  • Open Access
5 Citations
2,188 Views
11 Pages

Small Intestinal Polyp Burden in Pediatric Peutz–Jeghers Syndrome Assessed through Capsule Endoscopy: A Longitudinal Study

  • Jeremy Stewart,
  • Nathan R. Fleishman,
  • Vincent S. Staggs,
  • Mike Thomson,
  • Nicole Stoecklein,
  • Caitlin E. Lawson,
  • Michael P. Washburn,
  • Shahid Umar and
  • Thomas M. Attard

12 October 2023

The management of pediatric Peutz–Jeghers Syndrome (PJS) focuses on the prevention of intussusception complicating small intestinal (SI) polyposis. This hinges on the accurate appraisal of the polyp burden to tailor therapeutic interventions. V...

  • Article
  • Open Access
3 Citations
3,459 Views
10 Pages

Knowledge, Beliefs, and Behaviors of Turkish Parents about Childhood Vaccination

  • Zuhal Emlek Sert,
  • Sevcan Topçu and
  • Aysun Çelebioğlu

12 October 2023

Background and Objectives: Vaccination is critical to the prevention and control of infectious disease outbreaks and is also one of the most important public health successes. When it comes to childhood vaccinations, parents’ consent is very im...

  • Article
  • Open Access
9 Citations
2,601 Views
13 Pages

Characteristics of the Inflammatory Bowel Disease in Children: A Croatian Single-Centre Retrospective Study

  • Ivan Pivac,
  • Antonia Jelicic Kadic,
  • Ranka Despot,
  • Vanda Zitko,
  • Darija Tudor,
  • Edita Runjic and
  • Josko Markic

11 October 2023

Inflammatory bowel diseases (IBDs), encompassing ulcerative colitis (UC) and Crohn’s disease (CD), are chronic gastrointestinal disorders often diagnosed in youth, presenting unique features compared to adult-onset cases. We aimed to profile pe...

  • Review
  • Open Access
17 Citations
4,567 Views
15 Pages

Effectiveness of School-Based Interventions in Europe for Promoting Healthy Lifestyle Behaviors in Children

  • Archontoula Drouka,
  • Dora Brikou,
  • Céline Causeret,
  • Nur Al Ali Al Malla,
  • Stéphane Sibalo,
  • Concha Ávila,
  • Gabriela Alcat,
  • Anastasia E. Kapetanakou,
  • Patricia Gurviez and
  • Mary Yannakoulia
  • + 3 authors

11 October 2023

The objective of this narrative review was to summarize existing literature on the effectiveness of school-based interventions, implemented in Europe, under the aim of promoting healthy lifestyle behaviors in children (6–10 years old). A search...

  • Review
  • Open Access
9 Citations
4,454 Views
11 Pages

Sleep Disordered Breathing in Children with Neuromuscular Disease

  • Ambika G. Chidambaram,
  • Sanjay Jhawar,
  • Craig M. McDonald and
  • Kiran Nandalike

11 October 2023

Sleep disordered breathing (SDB) in children with neuromuscular disease (NMD) is more prevalent compared to the general population, and often manifests as sleep-related hypoventilation, sleep-related hypoxemia, obstructive sleep apnea, central sleep...

  • Article
  • Open Access
16 Citations
6,304 Views
17 Pages

Promoting Equity in Access to Quality Early Childhood Education in China

  • Nirmala Rao,
  • Yi Yang,
  • Yufen Su and
  • Caroline Cohrssen

10 October 2023

This paper reviews the Chinese government’s efforts and progress towards ensuring equitable access to quality early childhood education (ECE). It begins with an overview of the Chinese context and analysing the reasons for a policy focus on ECE...

  • Brief Report
  • Open Access
3 Citations
1,769 Views
9 Pages

10 October 2023

Standardized protocols have been designed and developed specifically for clinical information collection and obtaining trio genomic information from infants affected with congenital anomalies (CA) and their parents, as well as securing human biologic...

  • Review
  • Open Access
12 Citations
8,649 Views
12 Pages

Clinical Management and Therapy of Precocious Puberty in the Sapienza University Pediatrics Hospital of Rome, Italy

  • Ginevra Micangeli,
  • Roberto Paparella,
  • Francesca Tarani,
  • Michela Menghi,
  • Giampiero Ferraguti,
  • Francesco Carlomagno,
  • Matteo Spaziani,
  • Ida Pucarelli,
  • Antonio Greco and
  • Luigi Tarani
  • + 1 author

10 October 2023

Puberty identifies the transition from childhood to adulthood. Precocious puberty is the onset of signs of pubertal development before age eight in girls and before age nine in boys, it has an incidence of 1/5000–1/10,000 with an F:M ratio rang...

  • Review
  • Open Access
2 Citations
2,728 Views
9 Pages

9 October 2023

Nasal nitric oxide (nNO) is a gas synthesized by the inducible and constitutive NO synthase (NOS) enzyme in the airway cells of the nasal mucosa. Like lung nitric oxide, it is thought to be associated with airway inflammation in various respiratory d...

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Children - ISSN 2227-9067