Signalling Pathways in Cancer and Disease
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cancer Biology".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 459
Special Issue Editors
Interests: hippo signalling; mechanotransduction; YAP; cancer; polarity; Rho GTPases; signalling; organ growth; extracellular matrix; integrins; drug repurposing in cancer
Special Issues, Collections and Topics in MDPI journals
Interests: breast; cancer; non-coding; RNA; diagnostic; H19; microRNA-675; microRNA let 7; CA 15-3; drug repurposing in cancer
Special Issue Information
Dear Colleagues,
Cellular signalling pathways are integral to the regulation of essential biological processes across all forms of life and diseases. These pathways govern a wide array of cellular functions, including proliferation, cell–cell adhesion, extracellular matrix interactions, mechanotransduction, polarity establishment, and programmed cell death (apoptosis). The precise orchestration of these processes is critical for maintaining cellular and tissue homeostasis.
Disruptions or aberrations in these key signalling networks can lead to pathological outcomes, most notably cancer. Dysregulated signalling can drive oncogenesis, tumour progression, metastasis, and resistance to therapy. Understanding the molecular underpinnings of these pathways is therefore vital for identifying novel therapeutic targets and developing effective treatment strategies.
This Special Issue invites original article submissions and special reviews that explore the complexity of cellular signalling in the context of cancer. We particularly welcome studies that provide new insights into the mechanisms by which signalling pathways are altered in malignancy, as well as those that highlight innovative approaches to modulating these pathways for therapeutic benefit, to ensure that we can look at treating this debilitating disease with different methods.
Our goal is to advance the current understanding of signalling dynamics in cancer biology and to foster the development of translational strategies aimed at combating this multifaceted disease.
We look forward to your contributions to this Special Issue.
Dr. Ahmed Elbediwy
Guest Editor
Dr. Nadine Wehida
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer
- signalling
- metastasis
- tumorigenesis
- cancer targeting
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