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Biology, Volume 13, Issue 4

April 2024 - 81 articles

Cover Story: Many proteins are glycosylated, for example, on asparagine residues, which can affect protein function in a variety of ways, but can also shield immunogenic sites in viral proteins from the immune system. This is also the case for highly glycosylated SARS-CoV-2 proteins. In this study, different receptor-binding domains (RBDs) of several SARS-CoV-2 variants of concern (VOCs), a subunit of the highly glycosylated spike protein, and the membrane protein, which has not been extensively studied, were produced in human cells and bacteria for the relevant VOCs. The resulting RBDs were analyzed for their N-glycosylation sites by mass spectrometry and for their ability to bind to IgG antibodies produced in response to SARS-CoV-2 infection by ELISA. View this paper
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Articles (81)

  • Article
  • Open Access
2 Citations
3,193 Views
23 Pages

Genomic Diversity and Recombination Analysis of the Spike Protein Gene from Selected Human Coronaviruses

  • Sayed Sartaj Sohrab,
  • Fatima Alsaqaf,
  • Ahmed Mohamed Hassan,
  • Ahmed Majdi Tolah,
  • Leena Hussein Bajrai and
  • Esam Ibraheem Azhar

22 April 2024

Human coronaviruses (HCoVs) are seriously associated with respiratory diseases in humans and animals. The first human pathogenic SARS-CoV emerged in 2002–2003. The second was MERS-CoV, reported from Jeddah, the Kingdom of Saudi Arabia, in 2012,...

  • Article
  • Open Access
12 Citations
3,094 Views
14 Pages

21 April 2024

Ammonia is a major water quality factor influencing the survival and health of shrimp, among which the gill is the main effector organ for ammonia toxicity. In this study, we chose two types of Litopenaeus vannamei that were cultured in 30‰ se...

  • Article
  • Open Access
2 Citations
2,393 Views
18 Pages

Genome-Wide Analysis of the HSF Gene Family Reveals Its Role in Astragalus mongholicus under Different Light Conditions

  • Zhen Wang,
  • Panpan Wang,
  • Jiajun He,
  • Lingyang Kong,
  • Wenwei Zhang,
  • Weili Liu,
  • Xiubo Liu and
  • Wei Ma

19 April 2024

Astragalus mongholicus is a traditional Chinese medicine (TCM) with important medicinal value and is widely used worldwide. Heat shock (HSF) transcription factors are among the most important transcription factors in plants and are involved in the tr...

  • Article
  • Open Access
19 Citations
4,929 Views
26 Pages

19 April 2024

The Atlantic blue crab Callinectes sapidus, which is native to the western Atlantic coast and listed among the 100 most invasive alien species in the Mediterranean Sea, is attracting a great deal of interest because of its rapid colonisation of new a...

  • Article
  • Open Access
2 Citations
2,514 Views
22 Pages

Impaired Spermatogenesis in Infertile Patients with Orchitis and Experimental Autoimmune Orchitis in Rats

  • María Sofía Amarilla,
  • Leilane Glienke,
  • Thaisy Munduruca Pires,
  • Cristian Marcelo Sobarzo,
  • Hernán Gustavo Oxilia,
  • María Florencia Fulco,
  • Marcelo Rodríguez Peña,
  • María Belén Maio,
  • Denisse Ferrer Viñals and
  • Livia Lustig
  • + 2 authors

19 April 2024

Experimental autoimmune orchitis (EAO) is a well-established rodent model of organ-specific autoimmunity associated with infertility in which the testis immunohistopathology has been extensively studied. In contrast, analysis of testis biopsies from...

  • Article
  • Open Access
1 Citations
3,095 Views
17 Pages

Utilizing 5′ UTR Engineering Enables Fine-Tuning of Multiple Genes within Operons to Balance Metabolic Flux in Bacillus subtilis

  • Jiajia You,
  • Yifan Wang,
  • Kang Wang,
  • Yuxuan Du,
  • Xiaoling Zhang,
  • Xian Zhang,
  • Taowei Yang,
  • Xuewei Pan and
  • Zhiming Rao

19 April 2024

The application of synthetic biology tools to modulate gene expression to increase yield has been thoroughly demonstrated as an effective and convenient approach in industrial production. In this study, we employed a high-throughput screening strateg...

  • Article
  • Open Access
1 Citations
2,394 Views
15 Pages

Dissecting Holistic Metabolic Acclimatization of Mucor circinelloides WJ11 Defective in Carotenoid Biosynthesis

  • Fanyue Li,
  • Roypim Thananusak,
  • Nachon Raethong,
  • Junhuan Yang,
  • Mingyue Wei,
  • Xingtang Zhao,
  • Kobkul Laoteng,
  • Yuanda Song and
  • Wanwipa Vongsangnak

18 April 2024

Mucor circinelloides WJ11 is a lipid-producing strain with industrial potential. A holistic approach using gene manipulation and bioprocessing development has improved lipid production and the strain’s economic viability. However, the systemati...

  • Article
  • Open Access
4 Citations
4,010 Views
24 Pages

18 April 2024

We sampled vegetation communities across plant invasion gradients at multiple wetland and stream mitigation sites in the Coastal Plain and Piedmont physiographic provinces of Virginia, USA. Impacts of invasion were evaluated by tracking changes in sp...

  • Article
  • Open Access
8 Citations
2,205 Views
14 Pages

18 April 2024

Herbivorous insects rely on volatile chemical cues from host plants to locate food sources and oviposition sites. General odorant binding proteins (GOBPs) are believed to be involved in the detection of host plant volatiles. In the present study, one...

  • Article
  • Open Access
2 Citations
2,628 Views
15 Pages

Potential of a Bead-Based Multiplex Assay for SARS-CoV-2 Antibody Detection

  • Karla Rottmayer,
  • Mandy Schwarze,
  • Christian Jassoy,
  • Ralf Hoffmann,
  • Henry Loeffler-Wirth and
  • Claudia Lehmann

18 April 2024

Serological assays for SARS-CoV-2 play a pivotal role in the definition of whether patients are infected, the understanding of viral epidemiology, the screening of convalescent sera for therapeutic and prophylactic purposes, and in obtaining a better...

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Biology - ISSN 2079-7737Creative Common CC BY license