You are currently viewing a new version of our website. To view the old version click .

Antibiotics, Volume 9, Issue 6

June 2020 - 85 articles

Cover Story: Invasive fungal infections still constitute a major health problem, especially when affecting immunocompromised patients. A microbial natural products research program focused on the discovery of new antifungal compounds led to the identification and isolation of TKR 2999 from cultures of the fungus Foliophoma fallens, isolated from Pinus sp. using a dilution to extinction method. The structure of this lipodepsipeptide has been solved by spectroscopic and chemical methods and disclosed more than 20 years after its first report in a Japanese patent. The potent antifungal bioactivity of the molecule against Candida and Aspergillus species, the main pathogens causing fungal infections, has also been confirmed in our studies. Based on our results, Foliophoma has been identified as a genus to be added to the extensive list of fungal genera which are producers of interesting bioactive molecules. Vie

Articles (85)

  • Article
  • Open Access
27 Citations
6,582 Views
24 Pages

Isolation and Characterization of Pectobacterium Phage vB_PatM_CB7: New Insights into the Genus Certrevirus

  • Colin Buttimer,
  • Caoimhe Lynch,
  • Hanne Hendrix,
  • Horst Neve,
  • Jean-Paul Noben,
  • Rob Lavigne and
  • Aidan Coffey

To date, Certrevirus is one of two genera of bacteriophage (phage), with phages infecting Pectobacterium atrosepticum, an economically important phytopathogen that causes potato blackleg and soft rot disease. This study provides a detailed descriptio...

  • Article
  • Open Access
20 Citations
6,031 Views
15 Pages

Label-Free Electrochemical Microfluidic Chip for the Antimicrobial Susceptibility Testing

  • Hyoil Jeon,
  • Zeeshan A. Khan,
  • Emad Barakat and
  • Seungkyung Park

The emergence and spread of antibiotic-resistant bacteria is a global threat to human health. An accurate antibiotic susceptibility test (AST) before initiating the treatment is paramount in the treatment and bacterial resistance control. However, th...

  • Article
  • Open Access
31 Citations
11,839 Views
12 Pages

University Students’ Antibiotic Use and Knowledge of Antimicrobial Resistance: What Are the Common Myths?

  • Nurul Shaheera Shahpawee,
  • Li Ling Chaw,
  • Siti Hanna Muharram,
  • Hui Poh Goh,
  • Zahid Hussain and
  • Long Chiau Ming

We aimed to assess antibiotic usage and knowledge regarding antibiotics and antimicrobial resistance (AMR) among undergraduate students of the Universiti Brunei Darussalam (UBD), public university located in Brunei Darussalam. A cross-sectional study...

  • Article
  • Open Access
15 Citations
4,608 Views
13 Pages

Crystallography, in Silico Studies, and In Vitro Antifungal Studies of 2,4,5 Trisubstituted 1,2,3-Triazole Analogues

  • Katharigatta N. Venugopala,
  • Mohammed A. Khedr,
  • Yarabahally R. Girish,
  • Subhrajyoti Bhandary,
  • Deepak Chopra,
  • Mohamed A. Morsy,
  • Bandar E. Aldhubiab,
  • Pran Kishore Deb,
  • Mahesh Attimarad and
  • Anroop B. Nair
  • + 8 authors

A series of 2,4,5 trisubstituted-1,2,3-triazole analogues have been screened for their antifungal activity against five fungal strains, Candida parapsilosis, Candida albicans, Candida tropicalis, Aspergillus niger, and Trichophyton rubrum, via a 3-[4...

  • Article
  • Open Access
43 Citations
5,449 Views
12 Pages

Chalcones Isolated from Arrabidaea brachypoda Flowers as Inhibitors of NorA and MepA Multidrug Efflux Pumps of Staphylococcus aureus

  • Luís Mário Rezende-Júnior,
  • Leila Maria de Sousa Andrade,
  • Antonio Linkoln Alves Borges Leal,
  • Avilnete Belem de Souza Mesquita,
  • Ana Lurdes Portela de Araújo dos Santos,
  • José de Sousa Lima Neto,
  • José Pinto Siqueira-Júnior,
  • Carlos Emídio Sampaio Nogueira,
  • Glenn William Kaatz and
  • Henrique Douglas Melo Coutinho
  • + 3 authors

Bacterial resistance to antibiotics has become a public health issue around the world. The present study aimed to evaluate the antibacterial activity of chalcones isolated from flowers of Arrabidaea brachypoda, and their potential as efflux pump inhi...

  • Article
  • Open Access
5 Citations
3,916 Views
14 Pages

Studying the Gene Expression of Penicillium rubens Under the Effect of Eight Essential Oils

  • Zuzana Kisová,
  • Andrea Šoltýsová,
  • Mária Bučková,
  • Gábor Beke,
  • Andrea Puškárová and
  • Domenico Pangallo

Essential oils (EOs) are well-known for their beneficial properties against a broad range of microorganisms. For the better understanding of their mechanism of action in fungi, a microarray approach was used in order to evaluate the gene expression o...

  • Article
  • Open Access
14 Citations
4,916 Views
14 Pages

Essential oils (EOs) and honeybee products (e.g., honey and propolis) are natural mixtures of different volatile compounds that are frequently used in traditional medicine and for pathogen eradication. The aim of this study was to evaluate the antiba...

  • Article
  • Open Access
20 Citations
5,035 Views
9 Pages

Clinical Findings and Antimicrobial Susceptibility of Anaerobic Bacteria Isolated in Bloodstream Infections

  • Fernando Cobo,
  • Jaime Borrego,
  • Esther Gómez,
  • Isabel Casanovas,
  • Elizabeth Calatrava,
  • Carla Foronda and
  • José María Navarro-Marí

The objectives of this study were to report on the antimicrobial susceptibility of 141 clinically significant anaerobic bacteria isolated from bloodstream infections between January 2016 and April 2020 in a tertiary-care hospital in Granada (Spain) a...

  • Editorial
  • Open Access
14 Citations
4,314 Views
7 Pages

Antimicrobial resistance represents one of the most relevant threats to global public health and food security, affecting anyone, of any age, in any country and is responsible for longer hospital stays, higher medical costs and increased mortality. R...

  • Article
  • Open Access
47 Citations
4,675 Views
11 Pages

Antibacterial Properties of Nano-Ag Coating on Healing Abutment: An In Vitro and Clinical Study

  • Tetsurou Odatsu,
  • Shinichiro Kuroshima,
  • Mika Sato,
  • Kazuma Takase,
  • Alireza Valanezhad,
  • Mariko Naito and
  • Takashi Sawase

Peri-implantitis is an inflammatory disease with a relevant focus on the long-term success of dental implants and implant-supported prostheses. The present study focuses on the antibacterial effect of the silver nanoparticle and investigated the supp...

of 9

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Antibiotics - ISSN 2079-6382