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Journal of Clinical Medicine, Volume 13, Issue 5

March-1 2024 - 338 articles

Cover Story: Sepsis is a potentially lethal medical condition with a time-sensitive window for treatment. Distinguishing between sepsis and non-infectious causes of systemic inflammation can be clinically challenging, especially early in illness when no site of infection or pathogen has been identified, and organ damage is not yet evident. SeptiCyte RAPID, a US FDA-cleared host-response gene-expression assay, is an aid for diagnosing sepsis. SeptiCyte RAPID discriminates between sepsis and non-infectious systemic inflammation with an area under the receiver operating a characteristic curve of 0.82–0.95 (depending upon cohort) and provides a probability of sepsis within 60 minutes.This study suggests that SeptiCyte RAPID alone, or when combined with commonly used demographic, clinical, or laboratory variables, can contribute clinical utility for the early identification of sepsis. View this paper
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Articles (338)

  • Article
  • Open Access
11 Citations
3,801 Views
13 Pages

Noise-Optimized CBCT Imaging of Temporomandibular Joints—The Impact of AI on Image Quality

  • Wojciech Kazimierczak,
  • Kamila Kędziora,
  • Joanna Janiszewska-Olszowska,
  • Natalia Kazimierczak and
  • Zbigniew Serafin

5 March 2024

Background: Temporomandibular joint disorder (TMD) is a common medical condition. Cone beam computed tomography (CBCT) is effective in assessing TMD-related bone changes, but image noise may impair diagnosis. Emerging deep learning reconstruction alg...

  • Article
  • Open Access
2 Citations
2,419 Views
10 Pages

5 March 2024

Purpose: Mutations in Topoisomerase I–binding RS protein (TOPORS) have been previously documented and have been described to result in pathological autosomal dominant retinitis pigmentosa (adRP). In our study, we describe the various genotypes...

  • Systematic Review
  • Open Access
10 Citations
3,706 Views
13 Pages

The Role of Adjuvant Therapy for the Treatment of Micrometastases in Endometrial Cancer: A Systematic Review and Meta-Analysis

  • Carlo Ronsini,
  • Stefania Napolitano,
  • Irene Iavarone,
  • Pietro Fumiento,
  • Maria Giovanna Vastarella,
  • Antonella Reino,
  • Rossella Molitierno,
  • Lugi Cobellis,
  • Pasquale De Franciscis and
  • Stefano Cianci

5 March 2024

Endometrial cancer is the most incident gynecological cancer. Lymph node dissemination is one of the most important factors for the patient’s prognosis. Pelvic lymph nodes are the primary site of extra-uterine dissemination in endometrial cance...

  • Review
  • Open Access
2 Citations
3,199 Views
21 Pages

Hearing Loss in Baraitser–Winter Syndrome: Case Reports and Review of the Literature

  • Sara Ghiselli,
  • Giulia Parmeggiani,
  • Giulia Zambonini and
  • Domenico Cuda

5 March 2024

Background: Baraitser–Winter Syndrome (BRWS) is a rare autosomal dominant condition associated with hearing loss (HL). In the literature, two types of this condition are reported, Baraitser–Winter type 1 (BRWS1) and type 2 (BRWS2) produce...

  • Review
  • Open Access
6 Citations
2,363 Views
9 Pages

The Management of a Geriatric Patient Using Dabigatran Therapy on Dentigerous Cyst with Oral Bleeding

  • Glauco Chisci,
  • Dafne Chisci,
  • Enea Chisci,
  • Viola Chisci,
  • Michela Stumpo and
  • Elettra Chisci

5 March 2024

Jaw cysts represent a great matter of interest in oral and maxillofacial surgery. Jaw cyst surgery is a common intervention in oral surgery but, in the case of a multidisciplinary patient, the oral surgeon needs to meet with other specialists. A cyst...

  • Article
  • Open Access
6 Citations
2,885 Views
24 Pages

“Real-Time Neuromonitoring” Increases the Safety and Non-Invasiveness and Shortens the Duration of Idiopathic Scoliosis Surgery

  • Przemysław Daroszewski,
  • Juliusz Huber,
  • Katarzyna Kaczmarek,
  • Piotr Janusz,
  • Paweł Główka,
  • Marek Tomaszewski and
  • Tomasz Kotwicki

5 March 2024

Introduction: A practical solution to the incidental unreliability of intraoperative neuromonitoring (IONM) may be the simultaneous neurophysiological recording and control of the surgical field through a camera (the concept of “Real-time&rdquo...

  • Article
  • Open Access
2,046 Views
10 Pages

Outcomes of Severe ARDS COVID-19 Patients Denied for Venovenous ECMO Support: A Prospective Observational Comparative Study

  • Aude Sylvestre,
  • Jean-Marie Forel,
  • Laura Textoris,
  • Ines Gragueb-Chatti,
  • Florence Daviet,
  • Saida Salmi,
  • Mélanie Adda,
  • Antoine Roch,
  • Laurent Papazian and
  • Sami Hraiech
  • + 1 author

5 March 2024

Background: Few data are available concerning the outcome of patients denied venovenous extracorporeal membrane oxygenation (VV-ECMO) relative to severe acute respiratory distress syndrome (ARDS) due to COVID-19. Methods: We compared the 90-day survi...

  • Article
  • Open Access
6 Citations
8,357 Views
12 Pages

5 March 2024

Background: Percutaneous vertebroplasty (PVP) and kyphoplasty (PKP) are established methods in the treatment of vertebral compression fractures (VCFs). In our manuscript, the target was to evaluate the efficacy of PVPs/PKPs and to determine the impli...

  • Review
  • Open Access
6 Citations
7,974 Views
14 Pages

The Role of IVC Filters in the Management of Acute Pulmonary Embolism

  • Samer Asmar,
  • George Michael,
  • Vincent Gallo and
  • Mitchell D. Weinberg

5 March 2024

Venous thromboembolism (VTE), comprising deep venous thrombosis (DVT) and pulmonary embolism (PE), is a prevalent cardiovascular condition, ranking third globally after myocardial infarction and stroke. The risk of VTE rises with age, posing a growin...

  • Review
  • Open Access
8 Citations
3,096 Views
13 Pages

Severity of Complications after Locking Plate Osteosynthesis in Distal Femur Fractures

  • Roshan Gurung,
  • Alexander Terrill,
  • Gentry White,
  • Markus Windolf,
  • Ladina Hofmann-Fliri,
  • Constantin Dlaska,
  • Michael Schuetz and
  • Devakara R. Epari

5 March 2024

Background: Locked plating for distal femur fractures is widely recommended and used. We systematically reviewed clinical studies assessing the benefits and harms of fracture fixation with locked plates in AO/OTA Type 32 and 33 femur fractures. Metho...

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J. Clin. Med. - ISSN 2077-0383