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Journal of Clinical Medicine, Volume 13, Issue 6

March-2 2024 - 306 articles

Cover Story: Candida (C.) auris is a fungal pathogen; it is considered to be an emerging global health threat due to its rapid spread across the world and the emergence of strains that are resistant to multiple antifungal agents, thereby causing hospital infections in pediatric and adult populations, particularly in ICUs. Despite its widespread impact, there is a limited understanding of the clinical course and transmission dynamics of neonatal systemic C. auris infections, thereby hindering their effective prevention and management. Hence, there is a clinical need to understand the pathogenesis of C. auris infections during the neonatal period and to characterize the interactions between neonates and C. auris. Thus, we conducted a systematic review to gather and update our knowledge and practices concerning the risk factors, clinical presentation, and outcomes of C. auris infection in neonates. View this paper
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Articles (306)

  • Article
  • Open Access
1 Citations
2,299 Views
11 Pages

Trends of Early Helicobacter pylori-Uninfected Gastric Cancer in an Aging Regional Area

  • Hidehito Maeda,
  • Fumisato Sasaki,
  • Takayuki Ooi,
  • Shohei Uehara,
  • Hiroki Yano,
  • Yoichi Sameshima,
  • Yoshio Fukuda,
  • Yuichiro Nasu,
  • Yusuke Fujino and
  • Koichiro Shigeta
  • + 4 authors

21 March 2024

Background/Objectives: We aimed to determine the trends over time and current status of early Helicobacter pylori-uninfected gastric cancer (HpUIGC) treatment in a region with an aging population. Methods: This retrospective, multi-center observation...

  • Article
  • Open Access
3 Citations
3,016 Views
13 Pages

A Novel Method for Determining Fibrin/Fibrinogen Degradation Products and Fibrinogen Threshold Criteria via Artificial Intelligence in Massive Hemorrhage during Delivery with Hematuria

  • Yasunari Miyagi,
  • Katsuhiko Tada,
  • Ichiro Yasuhi,
  • Keisuke Tsumura,
  • Yuka Maegawa,
  • Norifumi Tanaka,
  • Tomoya Mizunoe,
  • Ikuko Emoto,
  • Kazuhisa Maeda and
  • Kosuke Kawakami
  • + 1 author

21 March 2024

(1) Background: Although the diagnostic criteria for massive hemorrhage with organ dysfunction, such as disseminated intravascular coagulation associated with delivery, have been empirically established based on clinical findings, strict logic has ye...

  • Article
  • Open Access
1 Citations
2,023 Views
12 Pages

Venous Thromboembolism Management throughout the COVID-19 Era: Addressing Acute and Long-Term Challenges

  • Maddalena Alessandra Wu,
  • Alba Taino,
  • Pietro Facchinetti,
  • Valentina Rossi,
  • Diego Ruggiero,
  • Silvia Berra,
  • Giulia Blanda,
  • Nicola Flor,
  • Chiara Cogliati and
  • Riccardo Colombo

21 March 2024

Background: COVID-19 increases the risk of venous thromboembolism (VTE) through a complex interplay of mechanisms collectively referred to as immunothrombosis. Limited data exist on VTE challenges in the acute setting throughout a dynamic long-term f...

  • Systematic Review
  • Open Access
3 Citations
4,037 Views
15 Pages

21 March 2024

(1) Background: The present review aims to identify risk factors with predictive value for differentiating between pseudoexfoliation patients at risk of developing intra- or postoperative complications and those without operative risk during cataract...

  • Article
  • Open Access
3 Citations
3,874 Views
12 Pages

21 March 2024

Background: We aimed to analyze the clinical outcomes and effectiveness of cervical biportal endoscopic spine surgery (C-BESS) and anterior cervical discectomy and fusion (ACDF) in patients with symptomatic cervical disc herniation. Methods: This stu...

  • Article
  • Open Access
5 Citations
3,585 Views
18 Pages

Recalled Maternal Rearing Behaviour of Individuals Born Preterm and Their Mothers: The Impact of Intimate Mother–Child Contact

  • Daniëlle Otten,
  • Mareike Ernst,
  • Alexander K. Schuster,
  • Jonas Tesarz,
  • Sandra Gißler,
  • Eva Mildenberger,
  • Norbert Pfeiffer,
  • Manfred E. Beutel and
  • Achim Fieß

21 March 2024

Background: Preterm birth is a risk factor for a variety of detrimental health outcomes. Previous studies have identified recalled (or remembered) parental rearing behaviour as a potential modifier of preterm individuals’ mental health in adult...

  • Article
  • Open Access
8 Citations
9,630 Views
13 Pages

Real-Life Comparison of Four JAK Inhibitors in Rheumatoid Arthritis (ELECTRA-i Study)

  • Maurizio Benucci,
  • Francesca Li Gobbi,
  • Arianna Damiani,
  • Edda Russo,
  • Serena Guiducci,
  • Mariangela Manfredi,
  • Barbara Lari,
  • Valentina Grossi and
  • Maria Infantino

21 March 2024

Background: Real-world evidence of the efficacy and adverse events of JAK inhibitor treatment (Tofacitinib, Baricitinib, Upadacitinib, and Filgotinib) in rheumatoid arthritis is still limited. Methods: We studied 115 patients from the Rheumatology Un...

  • Review
  • Open Access
15 Citations
7,903 Views
20 Pages

The Quality of Life in Patients with Spinal Cord Injury: Assessment and Rehabilitation

  • Davide Cardile,
  • Andrea Calderone,
  • Rosaria De Luca,
  • Francesco Corallo,
  • Angelo Quartarone and
  • Rocco Salvatore Calabrò

21 March 2024

Background and Objectives: Spinal Cord Injury (SCI) develops when the spinal cord is damaged and leads to partial or complete loss of motor and/or sensory function, usually below the level of injury. Medical advances in the last few decades have enab...

  • Article
  • Open Access
9 Citations
2,547 Views
15 Pages

21 March 2024

Background: To report on the outcome of intravitreal brolucizumab compared to aflibercept in patients with diabetic macular edema (DME). Methods: Prospective, observational, study in 35 eyes of 24 patients with a loading dose of five injections of 6...

  • Systematic Review
  • Open Access
10 Citations
5,602 Views
20 Pages

Aromatase Inhibitors and Plasma Lipid Changes in Postmenopausal Women with Breast Cancer: A Systematic Review and Meta-Analysis

  • Bálint Bérczi,
  • Nelli Farkas,
  • Péter Hegyi,
  • Barbara Tóth,
  • Dezső Csupor,
  • Balázs Németh,
  • Anita Lukács,
  • László Márk Czumbel,
  • Beáta Kerémi and
  • István Kiss
  • + 4 authors

21 March 2024

Background: Women are typically diagnosed with estrogen receptor-positive breast cancer around the postmenopausal period when declining estrogen levels initiate changes in lipid profiles. Aromatase inhibitors (AI) are used to prevent the progression...

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J. Clin. Med. - ISSN 2077-0383