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Journal of Clinical Medicine, Volume 13, Issue 4

February-2 2024 - 263 articles

Cover Story: According to the World Health Organization (WHO), the global seroprevalence of HBV in 2019 was 3.9%, with an estimated 820,000 HBV-associated deaths. Advanced fibrosis is a risk factor for the development of hepatocellular carcinoma and liver decompensation, and assessment of liver disease severity is important for treatment decisions in patients with Chronic Hepatitis B (CHB) with phases of infection and hepatitis. This review provides updated information on currently available non-invasive serum and imaging elastography tests for assessment of fibrosis severity. Imaging elastography may have better diagnostic performance for advanced disease, but simple blood-based tests continue to have utility for resource-limited areas. Optimal combinations of serum and imaging tests have not been established for assessment of fibrosis severity in CHB infection. View this paper
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Articles (263)

  • Review
  • Open Access
5 Citations
4,546 Views
13 Pages

19 February 2024

Gender-affirming hormone therapy (GAHT) is an important component in the process of transitioning for many transgender and gender-diverse (TGD) individuals. Multiple medical organizations recommend fertility preservation counseling prior to initiatio...

  • Review
  • Open Access
7 Citations
9,215 Views
16 Pages

Management of Neuromuscular Blocking Agents in Critically Ill Patients with Lung Diseases

  • Ida Giorgia Iavarone,
  • Lou’i Al-Husinat,
  • Jorge Luis Vélez-Páez,
  • Chiara Robba,
  • Pedro Leme Silva,
  • Patricia R. M. Rocco and
  • Denise Battaglini

19 February 2024

The use of neuromuscular blocking agents (NMBAs) is common in the intensive care unit (ICU). NMBAs have been used in critically ill patients with lung diseases to optimize mechanical ventilation, prevent spontaneous respiratory efforts, reduce the wo...

  • Article
  • Open Access
3 Citations
2,380 Views
14 Pages

Development and Internal Validation of a Model for Predicting Overall Survival in Subjects with MAFLD: A Cohort Study

  • Caterina Bonfiglio,
  • Angelo Campanella,
  • Rossella Donghia,
  • Antonella Bianco,
  • Isabella Franco,
  • Ritanna Curci,
  • Claudia Beatrice Bagnato,
  • Rossella Tatoli,
  • Gianluigi Giannelli and
  • Francesco Cuccaro

19 February 2024

Background & Aims: Fatty liver disease with metabolic dysfunction (MAFLD) is a new concept proposed to replace the previous concept of Non-Alcoholic Hepatic Steatosis (NAFLD). We developed and internally validated a prognostic model to predict th...

  • Review
  • Open Access
13 Citations
11,037 Views
11 Pages

Interactions between the Exocrine and the Endocrine Pancreas

  • Roberto Valente,
  • Alessandro Coppola,
  • Chiara Maria Scandavini,
  • Asif Halimi,
  • Annelie Magnusson,
  • Augusto Lauro,
  • Ira Sotirova,
  • Urban Arnelo and
  • Oskar Franklin

19 February 2024

The pancreas has two main functions: to produce and secrete digestive enzymes (exocrine function) and to produce hormones that regulate blood glucose and splanchnic secretion (endocrine function). The endocrine and exocrine portions of the pancreas a...

  • Article
  • Open Access
4 Citations
2,654 Views
15 Pages

Recognizing and Appreciating the Partner’s Support Protects Relationship Satisfaction during Cardiac Illness

  • Giada Rapelli,
  • Silvia Donato,
  • Emanuele Maria Giusti,
  • Giada Pietrabissa,
  • Miriam Parise,
  • Ariela Francesca Pagani,
  • Chiara A. M. Spatola,
  • Anna Bertoni and
  • Gianluca Castelnuovo

19 February 2024

Background: This study aimed to examine whether dyadic coping (DC) is associated with relationship satisfaction (RS) among couples facing cardiac diseases. Furthermore, the moderating role of both partners’ anxiety and depression was tested. Methods:...

  • Feature Paper
  • Article
  • Open Access
13 Citations
4,454 Views
17 Pages

Behavioral Disorders of Spatial Cognition in Patients with Mild Cognitive Impairment due to Alzheimer’s Disease: Preliminary Findings from the BDSC-MCI Project

  • Davide Maria Cammisuli,
  • Valeria Isella,
  • Federico Verde,
  • Vincenzo Silani,
  • Nicola Ticozzi,
  • Simone Pomati,
  • Virginia Bellocchio,
  • Valentina Granese,
  • Benedetta Vignati and
  • Gloria Marchesi
  • + 3 authors

19 February 2024

(1) Background: Spatial cognition (SC) is one of the earliest cognitive domains to be impaired in the course of Alzheimer’s disease (AD), resulting in spatial disorientation and becoming lost even in familiar surroundings as later dementia symp...

  • Article
  • Open Access
18 Citations
5,782 Views
15 Pages

Immediate Effect of Cryo-Compression Therapy on Biomechanical Properties and Perfusion of Forearm Muscles in Mixed Martial Arts Fighters

  • Robert Trybulski,
  • Adrian Kużdżał,
  • Marta Bichowska-Pawęska,
  • Andriy Vovkanych,
  • Adam Kawczyński,
  • Grzegorz Biolik and
  • Jarosław Muracki

19 February 2024

Mixed martial arts (MMA) fighters use their arms and hands for striking with the fists, grappling, and defensive techniques, which puts a high load on the forearms and hand muscles. New methods are needed to decrease the risk of injury and increase t...

  • Review
  • Open Access
6 Citations
3,582 Views
18 Pages

19 February 2024

Chronic kidney disease patients appear to be predisposed to heart rhythm disorders, including atrial fibrillation/atrial flutter, ventricular arrhythmias, and supraventricular tachycardias, which increase the risk of sudden cardiac death. The pathoph...

  • Article
  • Open Access
3 Citations
3,508 Views
11 Pages

19 February 2024

Background: The objective of this study is to establish a potential correlation between postoperative improvement in upper eyelid ptosis, measured by the marginal reflex distance 1 (MRD1), and the immediate postoperative degrees of lagophthalmos (IPD...

  • Systematic Review
  • Open Access
7 Citations
6,271 Views
15 Pages

19 February 2024

Background: Oral midazolam is the most commonly used sedative premedication agent in pediatric patients. While effective, oral midazolam cannot reduce the incidence of emergence agitation. Oral dexmedetomidine may be effective in providing satisfacto...

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J. Clin. Med. - ISSN 2077-0383