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Journal of Clinical Medicine, Volume 13, Issue 4

2024 February-2 - 263 articles

Cover Story: According to the World Health Organization (WHO), the global seroprevalence of HBV in 2019 was 3.9%, with an estimated 820,000 HBV-associated deaths. Advanced fibrosis is a risk factor for the development of hepatocellular carcinoma and liver decompensation, and assessment of liver disease severity is important for treatment decisions in patients with Chronic Hepatitis B (CHB) with phases of infection and hepatitis. This review provides updated information on currently available non-invasive serum and imaging elastography tests for assessment of fibrosis severity. Imaging elastography may have better diagnostic performance for advanced disease, but simple blood-based tests continue to have utility for resource-limited areas. Optimal combinations of serum and imaging tests have not been established for assessment of fibrosis severity in CHB infection. View this paper
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Articles (263)

  • Review
  • Open Access
5 Citations
4,703 Views
13 Pages

19 February 2024

Gender-affirming hormone therapy (GAHT) is an important component in the process of transitioning for many transgender and gender-diverse (TGD) individuals. Multiple medical organizations recommend fertility preservation counseling prior to initiatio...

  • Review
  • Open Access
8 Citations
9,607 Views
16 Pages

Management of Neuromuscular Blocking Agents in Critically Ill Patients with Lung Diseases

  • Ida Giorgia Iavarone,
  • Lou’i Al-Husinat,
  • Jorge Luis Vélez-Páez,
  • Chiara Robba,
  • Pedro Leme Silva,
  • Patricia R. M. Rocco and
  • Denise Battaglini

19 February 2024

The use of neuromuscular blocking agents (NMBAs) is common in the intensive care unit (ICU). NMBAs have been used in critically ill patients with lung diseases to optimize mechanical ventilation, prevent spontaneous respiratory efforts, reduce the wo...

  • Article
  • Open Access
3 Citations
2,482 Views
14 Pages

Development and Internal Validation of a Model for Predicting Overall Survival in Subjects with MAFLD: A Cohort Study

  • Caterina Bonfiglio,
  • Angelo Campanella,
  • Rossella Donghia,
  • Antonella Bianco,
  • Isabella Franco,
  • Ritanna Curci,
  • Claudia Beatrice Bagnato,
  • Rossella Tatoli,
  • Gianluigi Giannelli and
  • Francesco Cuccaro

19 February 2024

Background & Aims: Fatty liver disease with metabolic dysfunction (MAFLD) is a new concept proposed to replace the previous concept of Non-Alcoholic Hepatic Steatosis (NAFLD). We developed and internally validated a prognostic model to predict th...

  • Review
  • Open Access
13 Citations
11,484 Views
11 Pages

Interactions between the Exocrine and the Endocrine Pancreas

  • Roberto Valente,
  • Alessandro Coppola,
  • Chiara Maria Scandavini,
  • Asif Halimi,
  • Annelie Magnusson,
  • Augusto Lauro,
  • Ira Sotirova,
  • Urban Arnelo and
  • Oskar Franklin

19 February 2024

The pancreas has two main functions: to produce and secrete digestive enzymes (exocrine function) and to produce hormones that regulate blood glucose and splanchnic secretion (endocrine function). The endocrine and exocrine portions of the pancreas a...

  • Article
  • Open Access
4 Citations
2,822 Views
15 Pages

Recognizing and Appreciating the Partner’s Support Protects Relationship Satisfaction during Cardiac Illness

  • Giada Rapelli,
  • Silvia Donato,
  • Emanuele Maria Giusti,
  • Giada Pietrabissa,
  • Miriam Parise,
  • Ariela Francesca Pagani,
  • Chiara A. M. Spatola,
  • Anna Bertoni and
  • Gianluca Castelnuovo

19 February 2024

Background: This study aimed to examine whether dyadic coping (DC) is associated with relationship satisfaction (RS) among couples facing cardiac diseases. Furthermore, the moderating role of both partners’ anxiety and depression was tested. Methods:...

  • Feature Paper
  • Article
  • Open Access
14 Citations
4,645 Views
17 Pages

Behavioral Disorders of Spatial Cognition in Patients with Mild Cognitive Impairment due to Alzheimer’s Disease: Preliminary Findings from the BDSC-MCI Project

  • Davide Maria Cammisuli,
  • Valeria Isella,
  • Federico Verde,
  • Vincenzo Silani,
  • Nicola Ticozzi,
  • Simone Pomati,
  • Virginia Bellocchio,
  • Valentina Granese,
  • Benedetta Vignati and
  • Gianluca Castelnuovo
  • + 3 authors

19 February 2024

(1) Background: Spatial cognition (SC) is one of the earliest cognitive domains to be impaired in the course of Alzheimer’s disease (AD), resulting in spatial disorientation and becoming lost even in familiar surroundings as later dementia symp...

  • Article
  • Open Access
21 Citations
6,053 Views
15 Pages

Immediate Effect of Cryo-Compression Therapy on Biomechanical Properties and Perfusion of Forearm Muscles in Mixed Martial Arts Fighters

  • Robert Trybulski,
  • Adrian Kużdżał,
  • Marta Bichowska-Pawęska,
  • Andriy Vovkanych,
  • Adam Kawczyński,
  • Grzegorz Biolik and
  • Jarosław Muracki

19 February 2024

Mixed martial arts (MMA) fighters use their arms and hands for striking with the fists, grappling, and defensive techniques, which puts a high load on the forearms and hand muscles. New methods are needed to decrease the risk of injury and increase t...

  • Review
  • Open Access
6 Citations
3,711 Views
18 Pages

19 February 2024

Chronic kidney disease patients appear to be predisposed to heart rhythm disorders, including atrial fibrillation/atrial flutter, ventricular arrhythmias, and supraventricular tachycardias, which increase the risk of sudden cardiac death. The pathoph...

  • Article
  • Open Access
3 Citations
3,638 Views
11 Pages

19 February 2024

Background: The objective of this study is to establish a potential correlation between postoperative improvement in upper eyelid ptosis, measured by the marginal reflex distance 1 (MRD1), and the immediate postoperative degrees of lagophthalmos (IPD...

  • Systematic Review
  • Open Access
8 Citations
6,545 Views
15 Pages

19 February 2024

Background: Oral midazolam is the most commonly used sedative premedication agent in pediatric patients. While effective, oral midazolam cannot reduce the incidence of emergence agitation. Oral dexmedetomidine may be effective in providing satisfacto...

  • Case Report
  • Open Access
2 Citations
5,319 Views
8 Pages

19 February 2024

Neuromyelitis optica spectrum disease (NMOSD) is a rare autoimmune disorder of the central nervous system characterized by optic neuritis, myelitis, or brain lesions. Its symptoms overlap with those of multiple sclerosis (MS), making a diagnosis of N...

  • Article
  • Open Access
5 Citations
4,463 Views
24 Pages

19 February 2024

Background: This meta-analysis aimed to determine the efficacy and safety of antidiabetic agents in the treatment of major depressive disorder and bipolar depression. Methods: Randomized controlled trials (RCTs) of antidiabetic agents in major depres...

  • Article
  • Open Access
3 Citations
2,233 Views
13 Pages

Long-Term Functional Limitations on Cardiopulmonary Exercise Testing in Emotion-Triggered Takotsubo Syndrome

  • Jean Pierre Jabbour,
  • Luca Arcari,
  • Luca Cacciotti,
  • Damiano Magrì,
  • Tommaso Recchioni,
  • Livia Valeri,
  • Enrico Maggio,
  • Carmine Dario Vizza,
  • Roberto Badagliacca and
  • Silvia Papa

19 February 2024

Background: In patients with prior Takotsubo syndrome (TTS), long-lasting functional cardiac limitations were described as compared with normal subjects. Emotion-triggered Takotsubo syndrome (E-TTS) has more favorable outcomes than TTS preceded by a...

  • Article
  • Open Access
2 Citations
2,492 Views
14 Pages

Validation of the Italian Version of the Web Screening Questionnaire for Common Mental Disorders

  • Giada Pietrabissa,
  • Michelle Semonella,
  • Gloria Marchesi,
  • Stefania Mannarini,
  • Gianluca Castelnuovo,
  • Gerhard Andersson and
  • Alessandro Alberto Rossi

19 February 2024

Background: The ever-increasing spread of Internet-based systems for common mental disorders has generated the need for brief online screening methods. This study aims to test the psychometric properties of the Web Screening Questionnaire (WSQ) to ex...

  • Article
  • Open Access
7 Citations
2,377 Views
15 Pages

Expression of Tissue Inhibitors of Metalloproteinases (TIMP-1, TIMP-2, TIMP-3, TIMP-4) in Blood Serum of Patients with Keratoconus

  • Marta Nowak-Wąs,
  • Paweł Wąs,
  • Zenon Czuba,
  • Romuald Wojnicz and
  • Dorota Wyględowska-Promieńska

19 February 2024

Background: The etiology of keratoconus is unclear. Current evidence suggests that inflammatory and systemic mechanisms might play a role in its pathophysiology. The proper interaction of proteolytic enzymes—matrix metalloproteinases—and...

  • Article
  • Open Access
6 Citations
2,508 Views
13 Pages

Complications and Outcomes in 39,864 Patients Receiving Standard Care Plus Mechanical Circulatory Support or Standard Care Alone for Infarct-Associated Cardiogenic Shock

  • Jan-Sören Padberg,
  • Jannik Feld,
  • Leonie Padberg,
  • Jeanette Köppe,
  • Lena Makowski,
  • Joachim Gerß,
  • Patrik Dröge,
  • Thomas Ruhnke,
  • Christian Günster and
  • Holger Reinecke
  • + 1 author

19 February 2024

Background: Temporary mechanical circulatory support devices (tMCS) are increasingly being used in patients with infarct-associated cardiogenic shock (AMICS). Evidence on patient selection, complications and long-term outcomes is lacking. We aim to i...

  • Article
  • Open Access
4 Citations
2,904 Views
11 Pages

Suitable Patient Selection and Optimal Timing of Treatment for Persistent Air Leak after Lung Resection

  • Yoshikane Yamauchi,
  • Hiroyuki Adachi,
  • Nobumasa Takahashi,
  • Takao Morohoshi,
  • Taketsugu Yamamoto,
  • Makoto Endo,
  • Tsuyoshi Ueno,
  • Tekkan Woo,
  • Yuichi Saito and
  • Noriyoshi Sawabata

19 February 2024

Objectives: The choice of therapeutic intervention for postoperative air leak varies between institutions. We aimed to identify the optimal timing and patient criteria for therapeutic intervention in cases of postoperative air leaks after lung resect...

  • Article
  • Open Access
6 Citations
2,887 Views
13 Pages

Caries Experience before and after COVID-19 Restrictions: An Observational Study

  • Eduardo Guerreiro,
  • João Botelho,
  • Vanessa Machado,
  • Luís Proença,
  • José João Mendes and
  • Ana Cristina Manso

19 February 2024

Background: The declaration of COVID-19 as a pandemic by the World Health Organization in 2020 led to the suspension of several clinical practices globally, including dentistry. This study investigates the impact of these restrictions on dental carie...

  • Article
  • Open Access
3 Citations
3,320 Views
16 Pages

Influence of Cementation Mode and Ferrule Design on the Fatigue Resistance of Monolithic Zirconia Endocrowns

  • Milan Stoilov,
  • Tobias Boehmer,
  • Lea Stoilov,
  • Helmut Stark,
  • Michael Marder,
  • Norbert Enkling and
  • Dominik Kraus

19 February 2024

Background: Classic endocrowns made of dental ceramics are considered a promising alternative to traditional post-endodontic restorations. The use of circular ferrules in endocrowns is a topic of controversial discussion. Therefore, the present study...

  • Article
  • Open Access
5 Citations
6,257 Views
10 Pages

The Impact of Mechanical Bowel Preparation and Oral Antibiotics in Colorectal Cancer Surgery (MECCA Study): A Prospective Randomized Clinical Trial

  • Maximos Frountzas,
  • Victoria Michalopoulou,
  • Georgia Georgiou,
  • Despoina Kanata,
  • Maria Matiatou,
  • Despina Kimpizi,
  • Georgia Matthaiou,
  • Spilios Spiliotopoulos,
  • Dimitrios Vouros and
  • George E. Theodoropoulos
  • + 1 author

19 February 2024

Background: Colorectal cancer surgery has been associated with surgical site infections (SSIs), leading to an increase in postoperative morbidity, length of stay and total cost. The aim of the present randomized study was to investigate the relations...

  • Article
  • Open Access
1 Citations
3,792 Views
8 Pages

Diagnostic Value of Ileal Lesions Found during Colonoscopy with Reference to Endoscopic Indications and Findings

  • Dae Sung Kim,
  • Ji Eun Ryu,
  • Jieun Shin,
  • Hoon Sup Koo,
  • Sanghyuk Lee,
  • Hwanhyi Cho,
  • Jongheon Na and
  • Kyu Chan Huh

19 February 2024

The diagnostic value of ileoscopy is not well established, and its routine practice is controversial. We aimed to investigate the diagnostic value of biopsy for macroscopically abnormal lesions in the terminal ileum and to identify the association be...

  • Article
  • Open Access
14 Citations
4,342 Views
17 Pages

TGF-β1, pSmad-2/3, Smad-7, and β-Catenin Are Augmented in the Pulmonary Arteries from Patients with Idiopathic Pulmonary Fibrosis (IPF): Role in Driving Endothelial-to-Mesenchymal Transition (EndMT)

  • Archana Vijay Gaikwad,
  • Mathew Suji Eapen,
  • Surajit Dey,
  • Prem Bhattarai,
  • Affan Mahmood Shahzad,
  • Collin Chia,
  • Jade Jaffar,
  • Glen Westall,
  • Darren Sutherland and
  • Sukhwinder Singh Sohal
  • + 3 authors

19 February 2024

Background: We have previously reported that endothelial-to-mesenchymal transition (EndMT) is an active process in patients with idiopathic pulmonary fibrosis (IPF) contributing to arterial remodelling. Here, we aim to quantify drivers of EndMT in IP...

  • Article
  • Open Access
21 Citations
3,647 Views
9 Pages

Prevalence of Steatotic Liver Disease Based on a New Nomenclature in the Japanese Population: A Health Checkup-Based Cross-Sectional Study

  • Takao Miwa,
  • Satoko Tajirika,
  • Nanako Imamura,
  • Miho Adachi,
  • Ryo Horita,
  • Tatsunori Hanai,
  • Taku Fukao,
  • Masahito Shimizu and
  • Mayumi Yamamoto

19 February 2024

This cross-sectional study examined the prevalence and characteristics of steatotic liver disease (SLD) based on a recently introduced nomenclature in the Japanese health checkup population. SLD was evaluated using liver ultrasonography, and particip...

  • Article
  • Open Access
1 Citations
2,613 Views
12 Pages

Linear IgA Bullous Dermatosis in Korea Using the Nationwide Health Insurance Database

  • Yu Rim Kim,
  • Ji Hyeon Kim,
  • Sang Won Kim,
  • Jae Min Lee and
  • Jacob S. Bae

19 February 2024

(1) Background: Linear immunoglobulin A bullous dermatosis (LABD) is a rare autoimmune, subepidermal blistering disease, characterized by linear IgA deposits along the epidermal basement membrane. LABD is idiopathic and is associated with medication...

  • Review
  • Open Access
12 Citations
5,621 Views
11 Pages

19 February 2024

Myopia control with new designs of spectacle lenses is a flourishing area of research. The present work reviews the effectiveness of new designs (DIMSs, defocus-incorporated multiple segments; CARE, cylindrical annular refractive element; HALs/SALs,...

  • Case Report
  • Open Access
4 Citations
5,851 Views
17 Pages

19 February 2024

Introduction: Although various surgical techniques have been utilized in the reconstruction of severely resorbed alveolar bone, its regeneration is still regarded as a major challenge. Most of the surgical techniques used in advanced ridge augmentati...

  • Review
  • Open Access
24 Citations
12,483 Views
17 Pages

Exploring the Therapeutic Potential of Ganoderma lucidum in Cancer

  • Gabriella Cancemi,
  • Santino Caserta,
  • Sebastiano Gangemi,
  • Giovanni Pioggia and
  • Alessandro Allegra

18 February 2024

Triterpenoids, such as ganoderic acid, and polysaccharides, including β-D-glucans, α-D-glucans, and α-D-mannans, are the main secondary metabolites of the medicinal fungus Ganoderma lucidum. There is evidence of the effects of ganode...

  • Article
  • Open Access
2,612 Views
14 Pages

18 February 2024

Background/Objective: Monitoring multiple cellular markers of immune cells may provide a more accurate evaluation of the immune status of people living with human immunodeficiency virus (PLHIV). This study assessed the value of CD16+CD56+ cells (NK c...

  • Feature Paper
  • Article
  • Open Access
2 Citations
5,433 Views
18 Pages

Perspectives for the Use of Umbilical Cord Blood in Transplantation and Beyond: Initiatives for an Advanced and Sustainable Public Banking Program in Greece

  • Patra Pateraki,
  • Helen Latsoudis,
  • Anastasia Papadopoulou,
  • Ioanna Gontika,
  • Irene Fragiadaki,
  • Irene Mavroudi,
  • Nikoleta Bizymi,
  • Aristea Batsali,
  • Michail E. Klontzas and
  • Helen A. Papadaki
  • + 5 authors

18 February 2024

The umbilical cord blood (UCB) donated in public UCB banks is a source of hematopoietic stem cells (HSC) alternative to bone marrow for allogeneic HSC transplantation (HSCT). However, the high rejection rate of the donated units due to the strict acc...

  • Article
  • Open Access
5 Citations
2,213 Views
10 Pages

Impact of Implant Size and Position on Subsidence Degree after Anterior Cervical Discectomy and Fusion: Radiological and Clinical Analysis

  • Adam Bębenek,
  • Maciej Dominiak,
  • Grzegorz Karpiński,
  • Tomasz Pawełczyk and
  • Bartosz Godlewski

18 February 2024

Background: Implant subsidence is recognized as a complication of interbody stabilization, although its relevance remains ambiguous, particularly in terms of relating the effect of the position and depth of subsidence on the clinical outcome of the p...

  • Article
  • Open Access
2 Citations
2,582 Views
17 Pages

18 February 2024

Background: Laparoscopic surgery demands high precision and skill, necessitating effective training protocols that account for factors such as hand dominance. This study investigates the impact of hand dominance on the acquisition and proficiency of...

  • Article
  • Open Access
10 Citations
2,606 Views
16 Pages

A Comparative Analysis of Liver Injury Markers in Post-COVID Syndrome among Elderly Patients: A Prospective Study

  • Adrian Vasile Bota,
  • Felix Bratosin,
  • Satya Sai Sri Bandi,
  • Iulia Bogdan,
  • David Vladut Razvan,
  • Ana-Olivia Toma,
  • Mirela Florica Indries,
  • Andrei Nicolae Csep,
  • Coralia Cotoraci and
  • Iosif Marincu
  • + 3 authors

18 February 2024

Background: In the wake of the global COVID-19 pandemic, understanding its prolonged impact on vulnerable populations has become a critical area of investigation. This study aimed to elucidate the distinctive post-acute sequelae of SARS-CoV-2 infecti...

  • Systematic Review
  • Open Access
1 Citations
2,934 Views
15 Pages

Clinical, Radiologic, and Functional Outcomes following Bone Grafting for Metacarpal Non-Unions: A Systematic Review

  • Omar El Sewify,
  • Jad Abi-Rafeh,
  • Jack Legler,
  • Shayan Karimi,
  • Aslan Baradaran and
  • Johnny I. Efanov

18 February 2024

Objectives: Metacarpal non-unions are complex hand defects that can lead to severe hand impairment. Treatment may require the use of artificial or autologous bone grafts. This systematic review aims to describe the outcomes of bone grafting following...

  • Review
  • Open Access
8 Citations
2,308 Views
11 Pages

18 February 2024

Purpose: This review summarizes the current scope of understanding associated with two common post-infectious complications associated with COVID-19 infection: Multi-System Inflammatory Syndrome in Children (MIS-C) and Post-Acute Sequelae of SARS-CoV...

  • Study Protocol
  • Open Access
2 Citations
1,822 Views
11 Pages

Prospective Study on the Correlation between CART and Leptin Gene Expression, Obesity, and Reproductive Hormones in Individuals Undergoing Bariatric Surgery

  • Charalampos Voros,
  • Kyriakos Mpananis,
  • Angeliki Papapanagiotou,
  • Abraham Pouliakis,
  • Despoina Mavrogianni,
  • Konstantina Mavriki,
  • Ioannis Gkaniatsos,
  • Christina Karasmani,
  • Ioannis Prokopakis and
  • Ekaterini Domali
  • + 3 authors

18 February 2024

Obesity, a global health concern affecting 650 million individuals of all ages worldwide, prompts health complications, including fertility issues. This research investigates the impact of bariatric surgery on morbidly obese females under 40, examini...

  • Article
  • Open Access
2 Citations
2,204 Views
12 Pages

Developing a Nomogram for Prioritizing Hysteroscopy in Endometrial Cancer Diagnosis: A Case-Control Study

  • Bruna Bottura,
  • Raphael Federicci Haddad,
  • Vanessa Alvarenga-Bezerra,
  • Vinicius Campos,
  • Luiza Perez,
  • Carolina Resende,
  • Fernanda de Almeida Asencio,
  • Adolfo Wenjaw Liao,
  • Mariano Tamura Vieira Gomes and
  • Renato Moretti-Marques
  • + 1 author

18 February 2024

(1) Background: The pandemic led to significant healthcare disruptions, resulting in postponed surgeries and extended waiting times for non-urgent treatments, including hysteroscopies essential for diagnosing endometrial cancer. This study aims to fo...

  • Brief Report
  • Open Access
4 Citations
2,332 Views
9 Pages

Stage 5 Chronic Kidney Disease: Epidemiological Analysis in a NorthEastern District of Italy Focusing on Access to Nephrological Care

  • Francesca K. Martino,
  • Giulia Fanton,
  • Fiammetta Zanetti,
  • Mariarosa Carta,
  • Federico Nalesso and
  • Giacomo Novara

18 February 2024

Background: We conducted a retrospective epidemiological study about the prevalence of stage 5 chronic kidney disease (CKD) in a high-income district, comparing some demographic characteristics and outcomes of those patients who had nephrological con...

  • Review
  • Open Access
6 Citations
6,580 Views
22 Pages

Weight Regain after Metabolic Surgery: Beyond the Surgical Failure

  • Juan Salazar,
  • Pablo Duran,
  • Bermary Garrido,
  • Heliana Parra,
  • Marlon Hernández,
  • Clímaco Cano,
  • Roberto Añez,
  • Henry García-Pacheco,
  • Gabriel Cubillos and
  • Valmore Bermúdez
  • + 2 authors

18 February 2024

Patients undergoing metabolic surgery have factors ranging from anatomo-surgical, endocrine metabolic, eating patterns and physical activity, mental health and psychological factors. Some of the latter can explain the possible pathophysiological neur...

  • Article
  • Open Access
5 Citations
7,230 Views
15 Pages

Monitoring of Women with Anti-Ro/SSA and Anti-La/SSB Antibodies in Germany—Status Quo and Intensified Monitoring Concepts

  • Ivonne Alexandra Bedei,
  • David Kniess,
  • Corinna Keil,
  • Aline Wolter,
  • Johanna Schenk,
  • Ulrich J. Sachs and
  • Roland Axt-Fliedner

17 February 2024

Background: The fetuses of pregnant women affected by anti-Ro/anti-La antibodies are at risk of developing complete atrioventricular heart block (CAVB) and other potentially life-threatening cardiac affections. CAVB can develop in less than 24 h. Tre...

  • Article
  • Open Access
25 Citations
8,503 Views
13 Pages

Medial or Lateral, That Is the Question: A Retrospective Study to Compare Two Injection Techniques in the Treatment of Knee Osteoarthritis Pain with Hyaluronic Acid

  • Giacomo Farì,
  • Rachele Mancini,
  • Laura Dell’Anna,
  • Vincenzo Ricci,
  • Simone Della Tommasa,
  • Francesco Paolo Bianchi,
  • Ilaria Ladisa,
  • Carlo De Serio,
  • Silvia Fiore and
  • Marisa Megna
  • + 3 authors

17 February 2024

Background: Mild-to-moderate knee osteoarthritis (KOA) can be successfully treated using intra-articular hyaluronic acid (IA-HA). The medial infrapatellar (MIP) approach and lateral infrapatellar (LIP) approach are two of the most used techniques for...

  • Article
  • Open Access
6 Citations
3,117 Views
13 Pages

Neurodevelopmental Outcome after Culture-Proven or So-Called Culture-Negative Sepsis in Preterm Infants

  • Luca Bedetti,
  • Lucia Corso,
  • Francesca Miselli,
  • Isotta Guidotti,
  • Carlotta Toffoli,
  • Rossella Miglio,
  • Maria Federica Roversi,
  • Elisa della Casa Muttini,
  • Marisa Pugliese and
  • Alberto Berardi
  • + 5 authors

17 February 2024

(1) Background: Prematurity is a serious condition associated with long-term neurological disability. This study aimed to compare the neurodevelopmental outcomes of preterm neonates with or without sepsis. (2) Methods: This single-center retrospectiv...

  • Article
  • Open Access
1 Citations
3,990 Views
19 Pages

Down Syndrome—Basque Alzheimer Initiative (DS-BAI): Clinic-Biological Cohort

  • Miren Altuna,
  • Ainara Estanga,
  • Adolfo Garrido,
  • Jon Saldias,
  • Marta Cañada,
  • Maitane Echeverria,
  • José Ángel Larrea,
  • Patricia Ayo,
  • Ainhoa Fiz and
  • Maite García-Sebastián
  • + 3 authors

17 February 2024

Background: Down syndrome (DS) is the most common genetically determined intellectual disability. In recent decades, it has experienced an exponential increase in life expectancy, leading to a rise in age-related diseases, including Alzheimer’s...

  • Article
  • Open Access
1 Citations
2,009 Views
15 Pages

17 February 2024

Background: A relationship between glaucoma and epiretinal membrane (ERM) has been suggested previously. We investigated the association between intraocular pressure (IOP) fluctuation and idiopathic ERM in patients with glaucoma or glaucoma suspect....

  • Systematic Review
  • Open Access
8 Citations
7,687 Views
20 Pages

Transient Neonatal Myasthenia Gravis as a Common Complication of a Rare Disease: A Systematic Review

  • Jenny Linnea Victoria Lindroos,
  • Marte-Helene Bjørk and
  • Nils Erik Gilhus

17 February 2024

Myasthenia gravis (MG) is a rare autoimmune disease. Transient neonatal myasthenia gravis (TNMG) is caused by pathogenic maternal autoantibodies that cross the placenta and disrupt signaling at the neuromuscular junction. This is a systematic review...

  • Article
  • Open Access
5 Citations
1,787 Views
10 Pages

Risk Factor Analysis for Developing Major Complications Following Esophageal Surgery—A Two-Center Study

  • Björn-Ole Stüben,
  • Gabriel Andreas Plitzko,
  • Louisa Stern,
  • Rainer Schmeding,
  • Karl-Frederick Karstens,
  • Matthias Reeh,
  • Jürgen Walter Treckmann,
  • Jakob Robert Izbicki,
  • Fuat Hakan Saner and
  • Dieter Paul Hoyer
  • + 2 authors

17 February 2024

Background: Esophagectomy carries a high risk of morbidity and mortality compared to other major surgeries. With the aim of creating an easy-to-use clinical preoperative risk assessment tool and to validate previously described risk factors for major...

  • Article
  • Open Access
3 Citations
2,431 Views
10 Pages

Prognostic Factors for Severe-to-Fatal Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis: A Multicenter Prospective Cohort Study

  • Kazuya Matsumoto,
  • Hisashi Noma,
  • Koichi Fujita,
  • Takeshi Tomoda,
  • Takumi Onoyama,
  • Keiji Hanada,
  • Akihito Okazaki,
  • Ken Hirao,
  • Daisuke Goto and
  • Hirofumi Kawamoto
  • + 19 authors

17 February 2024

The prognostic factors associated with severe-to-fatal post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) remain unclear despite the extensive number of studies on PEP. In total, 3739 ERCP patients with biliary disease with...

  • Article
  • Open Access
6 Citations
2,480 Views
11 Pages

Long-Term Follow-Up of Custom-Made Porous Hydroxyapatite Cranioplasties: Analysis of Infections in Adult and Pediatric Patients

  • Francesca Carolina Mannella,
  • Francesca Faedo,
  • Marta Fumagalli,
  • Giuseppe Danilo Norata,
  • Ismail Zaed and
  • Franco Servadei

17 February 2024

In neurosurgery, cranioplasty (CP) stands as a pivotal surgical intervention, particularly following head trauma or various neurosurgical interventions. This study scrutinizes the intricacies of CP, emphasizing its prevalence and associated complicat...

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J. Clin. Med. - ISSN 2077-0383