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Antioxidants, Volume 11, Issue 1

January 2022 - 176 articles

Cover Story: Investigation of cell metabolism is hampered by the imprint of classical non-physiological media on various pathways. We evaluated changes in metabolism of four mammalian cell lines cultivated in human plasma-resembling Plasmax medium. This promoted the assembly of mitochondria into vast networks leading to enhanced respiration and increased sensitivity to respiration complex inhibitors. Plasmax also reduced lysosomal mass in cells. Cells maintained in Plasmax supported lower levels of replication of RNA viruses, including hepatitis C and influenza A viruses as well as SARS-CoV-2. Interestingly, levels of oxidative stress markers remained unchanged, pointing to a higher ability of the viruses in Plasmax to trigger ROS production. Altogether, these data clearly show that the physiological Plasmax medium should be used in metabolomics and redox biology studies. View this paper.
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Articles (176)

  • Review
  • Open Access
103 Citations
10,528 Views
26 Pages

Seaweed-Derived Proteins and Peptides: Promising Marine Bioactives

  • Javier Echave,
  • Paz Otero,
  • Paula Garcia-Oliveira,
  • Paulo E. S. Munekata,
  • Mirian Pateiro,
  • Jose M. Lorenzo,
  • Jesus Simal-Gandara and
  • Miguel A. Prieto

17 January 2022

Seaweeds are a typical food of East-Asian cuisine, to which are alleged several beneficial health effects have been attributed. Their availability and their nutritional and chemical composition have favored the increase in its consumption worldwide,...

  • Article
  • Open Access
21 Citations
5,017 Views
22 Pages

17 January 2022

Acremonium terricola culture (ATC) has similar bioactive constituents to Cordyceps and is known for its nutrient and pharmacological value, indicating the potential of ATC as a new feed additive in dairy cow feeding. The primary aim of this experimen...

  • Article
  • Open Access
21 Citations
4,341 Views
16 Pages

17 January 2022

Near-infrared (NIR) light-mediated photothermal therapy (PTT) and photodynamic therapy (PDT) have widely been used for cancer treatment applications. However, a number of limitations (e.g., low NIR absorption capacity of photothermal agents, insuffic...

  • Article
  • Open Access
8 Citations
3,434 Views
15 Pages

17 January 2022

To date, no effective drugs exist for amyotrophic lateral sclerosis (ALS), although riluzole (RZ) and edaravone have been approved for treatment. We previously reported that Bojungikgi-tang (BJIGT) improved motor activity through anti-inflammatory ef...

  • Review
  • Open Access
92 Citations
7,033 Views
20 Pages

Arterial Hypertension—Oxidative Stress and Inflammation

  • Julia Krzemińska,
  • Magdalena Wronka,
  • Ewelina Młynarska,
  • Beata Franczyk and
  • Jacek Rysz

17 January 2022

Arterial hypertension (AH) is a major cause of cardiovascular diseases (CVD), leading to dysfunction of many organs, including the heart, blood vessels and kidneys. AH is a multifactorial disease. It has been suggested that the development of each fa...

  • Article
  • Open Access
21 Citations
3,564 Views
13 Pages

17 January 2022

6,8-Diprenylorobol is a flavonoid compound extracted from Cudrania tricuspidata. It has various biological functions, such as inhibiting melanin synthesis and inducting cell death in cancerous cells. In addition, Cudrania tricuspidata is known to be...

  • Review
  • Open Access
49 Citations
7,799 Views
18 Pages

17 January 2022

Oxidative stress and neuroinflammation are common bases for disease onset and progression in many neurodegenerative diseases. In Parkinson disease, which is characterized by the degeneration of dopaminergic neurons resulting in dopamine depletion, th...

  • Review
  • Open Access
12 Citations
3,659 Views
18 Pages

Hydropersulfides (RSSH) and Nitric Oxide (NO) Signaling: Possible Effects on S-Nitrosothiols (RS-NO)

  • Jon M. Fukuto,
  • Cristina Perez-Ternero,
  • Jessica Zarenkiewicz,
  • Joseph Lin,
  • Adrian J. Hobbs and
  • John P. Toscano

16 January 2022

S-Nitrosothiol (RS-NO) formation in proteins and peptides have been implicated as factors in the etiology of many diseases and as possible regulators of thiol protein function. They have also been proposed as possible storage forms of nitric oxide (N...

  • Article
  • Open Access
27 Citations
5,940 Views
20 Pages

16 January 2022

Corn silk (Stigma maydis), rich in flavonoids, is traditionally used to treat edema, depression, and hyperglycemia and may alleviate ischemic stroke symptoms in Chinese medicine. This study examined whether corn silk water extract (CSW) could allevia...

  • Review
  • Open Access
41 Citations
7,298 Views
17 Pages

Antioxidant Paradox in Male Infertility: ‘A Blind Eye’ on Inflammation

  • Sulagna Dutta,
  • Pallav Sengupta,
  • Shubhadeep Roychoudhury,
  • Srikumar Chakravarthi,
  • Chee Woon Wang and
  • Petr Slama

16 January 2022

The pathophysiology of male infertility involves various interlinked endogenous pathways. About 50% of the cases of infertility in men are idiopathic, and oxidative stress (OS) reportedly serves as a central mechanism in impairing male fertility para...

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Antioxidants - ISSN 2076-3921