Next Article in Journal
Rumex japonicus Houtt. Protects Dopaminergic Neurons by Regulating Mitochondrial Function and Gut–Brain Axis in In Vitro and In Vivo Models of Parkinson’s Disease
Next Article in Special Issue
COVID-19 during Gestation: Maternal Implications of Evoked Oxidative Stress and Iron Metabolism Impairment
Previous Article in Journal
Effect of 5-Azacitidine Treatment on Redox Status and Inflammatory Condition in MDS Patients
Previous Article in Special Issue
Implications of Vitamins in COVID-19 Prevention and Treatment through Immunomodulatory and Anti-Oxidative Mechanisms
Review

Potential and Possible Therapeutic Effects of Melatonin on SARS-CoV-2 Infection

1
Department of Pathophysiology, Stavropol State Medical University, 355000 Stavropol, Russia
2
Department of Clinical Pharmacology, Stavropol State Medical University, 355000 Stavropol, Russia
3
Department of Pharmacology, Stavropol State Medical University, 355000 Stavropol, Russia
4
Center of Personalized Medicine, Stavropol State Medical University, 355000 Stavropol, Russia
*
Author to whom correspondence should be addressed.
Academic Editors: Javier Diaz-Castro, Jorge Moreno-Fernandez and Julio Ochoa Herrera
Antioxidants 2022, 11(1), 140; https://doi.org/10.3390/antiox11010140
Received: 21 December 2021 / Revised: 7 January 2022 / Accepted: 7 January 2022 / Published: 9 January 2022
(This article belongs to the Special Issue Oxidative Stress, Inflammatory Signaling, Nutrition and COVID-19)
The absence of effective drugs for COVID-19 prevention and treatment requires the search for new candidates among approved medicines. Fundamental studies and clinical observations allow us to approach an understanding of the mechanisms of damage and protection from exposure to SARS-CoV-2, to identify possible points of application for pharmacological interventions. In this review we presented studies on the anti-inflammatory, antioxidant, and immunotropic properties of melatonin. We have attempted to present scientifically proven mechanisms of action for the potential therapeutic use of melatonin during SARS-CoV-2 infection. A wide range of pharmacological properties allows its inclusion as an effective addition to the methods of prevention and treatment of COVID-19. View Full-Text
Keywords: melatonin; SARS-CoV-2; COVID-19; inflammation; cytokine storm melatonin; SARS-CoV-2; COVID-19; inflammation; cytokine storm
Show Figures

Figure 1

MDPI and ACS Style

Shchetinin, E.; Baturin, V.; Arushanyan, E.; Bolatchiev, A.; Bobryshev, D. Potential and Possible Therapeutic Effects of Melatonin on SARS-CoV-2 Infection. Antioxidants 2022, 11, 140. https://doi.org/10.3390/antiox11010140

AMA Style

Shchetinin E, Baturin V, Arushanyan E, Bolatchiev A, Bobryshev D. Potential and Possible Therapeutic Effects of Melatonin on SARS-CoV-2 Infection. Antioxidants. 2022; 11(1):140. https://doi.org/10.3390/antiox11010140

Chicago/Turabian Style

Shchetinin, Evgeny, Vladimir Baturin, Eduard Arushanyan, Albert Bolatchiev, and Dmitriy Bobryshev. 2022. "Potential and Possible Therapeutic Effects of Melatonin on SARS-CoV-2 Infection" Antioxidants 11, no. 1: 140. https://doi.org/10.3390/antiox11010140

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop