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Pathogens, Volume 12, Issue 4

April 2023 - 125 articles

Cover Story: Borrelia miyamotoi is an emerging pathogen that is transmitted by the same hard-bodied (ixodid) ticks that transmit Borrelia burgdorferi, the causative agent of Lyme disease. Human cases have been reported in North America, Europe, and Asia. In North America, B. miyamotoi infection is widespread in Ixodes ticks in the Northeastern, Northern Midwestern, and Far Western United States and in Canada. In endemic areas, human B. miyamotoi seroprevalence averages from 1 to 3% of the population, compared with 15 to 20% for B. burgdorferi. The most common clinical manifestations of B. miyamotoi infection are fever, fatigue, headache, chills, myalgia, arthralgia, and nausea. Complications include relapsing fever and meningoencephalitis. Diagnosis is confirmed by PCR or blood smear. Antibiotic therapy is the same as for Lyme disease. View this paper
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Articles (125)

  • Article
  • Open Access
3 Citations
3,293 Views
11 Pages

Establishment of a Simple and Rapid Nucleic Acid Detection Method for Hookworm Identification

  • Xin Ding,
  • Yougui Yang,
  • Yingshu Zhang,
  • Qiang Zhang,
  • Fanzhen Mao and
  • Yang Dai

Hookworm infection is one of the most common neglected tropical diseases and is mainly found in tropical and subtropical areas. Two species of human hookworm are distributed in China, i.e., Ancylostoma duodenale (AD) and Necator americanus (NA). Back...

  • Review
  • Open Access
5 Citations
2,990 Views
13 Pages

Legionella pneumophila is the causative agent of Legionnaires’ disease, causing fever and lung infection, with a death rate up to 15% in severe cases. In the process of infection, Legionella pneumophila secretes over 330 effectors into hos...

  • Article
  • Open Access
4 Citations
5,126 Views
15 Pages

Viability of African Swine Fever Virus with the Shallow Burial with Carbon Carcass Disposal Method

  • Hoang Minh Duc,
  • Mark Hutchinson,
  • Gary A. Flory,
  • Pham Hong Ngan,
  • Hoang Minh Son,
  • Le Van Hung,
  • Tran Thi Khanh Hoa,
  • Nguyen Thi Lan,
  • Truong Quang Lam and
  • Dale Rozeboom
  • + 5 authors

African swine fever (ASF) is a highly contagious swine disease with high mortality. In many countries, culling pigs infected and exposed to the ASF virus is mandatory to control the disease, which poses a real challenge in the disposal of large numbe...

  • Review
  • Open Access
5 Citations
3,479 Views
13 Pages

Familial Hypercholesterolemia and Acute Coronary Syndromes: The Microbiota–Immunity Axis in the New Diagnostic and Prognostic Frontiers

  • Andrea Piccioni,
  • Elena Niccolai,
  • Gloria Rozzi,
  • Giacomo Spaziani,
  • Christian Zanza,
  • Marcello Candelli,
  • Marcello Covino,
  • Antonio Gasbarrini,
  • Francesco Franceschi and
  • Amedeo Amedei

Familial hypercholesterolemia is a common genetic disorder with a propensity towards early onset of atherosclerotic cardiovascular disease (CVD). The main goal of therapy is to reduce the LDL cholesterol and the current treatment generally consists o...

  • Article
  • Open Access
4 Citations
3,073 Views
17 Pages

SARS-CoV-2 Variants by Whole-Genome Sequencing in a University Hospital in Bangkok: First to Third COVID-19 Waves

  • Chayanee Setthapramote,
  • Thanwa Wongsuk,
  • Chuphong Thongnak,
  • Uraporn Phumisantiphong,
  • Tonsan Hansirisathit and
  • Maytawan Thanunchai

Background: Multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants emerged globally during the recent coronavirus disease (COVID-19) pandemic. From April 2020 to April 2021, Thailand experienced three COVID-19 waves, and each...

  • Article
  • Open Access
2 Citations
2,268 Views
10 Pages

Neuroangiostrongyliasis (NAS) is an emerging tropical disease in humans and some animals which is caused by infection with the parasitic nematode Angiostrongylus cantonensis. It is the leading cause of eosinophilic meningitis worldwide. Diagnoses in...

  • Viewpoint
  • Open Access
9 Citations
4,277 Views
8 Pages

Neuroangiostrongyliasis: Updated Provisional Guidelines for Diagnosis and Case Definitions

  • Carlos Graeff-Teixeira,
  • Kittisak Sawanyawisuth,
  • Shan Lv,
  • William Sears,
  • Zhaily González Rodríguez,
  • Hilda Hernández Álvarez,
  • Pedro Casanova Arias,
  • Leticia Karolini Walger Schultz,
  • Alicia Rojas and
  • John Jacob
  • + 2 authors

Angiostrongylus cantonensis is the main causative agent for eosinophilic meningoencephalitis in humans. Larvae are rarely found in the cerebral spinal fluid (CSF). Consequently, serology and DNA detection represent important diagnostic tools. However...

  • Review
  • Open Access
210 Citations
60,896 Views
17 Pages

Urinary Tract Infections: The Current Scenario and Future Prospects

  • Giuseppe Mancuso,
  • Angelina Midiri,
  • Elisabetta Gerace,
  • Maria Marra,
  • Sebastiana Zummo and
  • Carmelo Biondo

Urinary tract infections (UTIs) are among the most common bacterial infections worldwide, occurring in both community and healthcare settings. Although the clinical symptoms of UTIs are heterogeneous and range from uncomplicated (uUTIs) to complicate...

  • Article
  • Open Access
3 Citations
2,952 Views
12 Pages

Feral Swine as Indirect Indicators of Environmental Anthrax Contamination and Potential Mechanical Vectors of Infectious Spores

  • Rachel M. Maison,
  • Maggie R. Priore,
  • Vienna R. Brown,
  • Michael J. Bodenchuk,
  • Bradley R. Borlee,
  • Richard A. Bowen and
  • Angela M. Bosco-Lauth

Anthrax is a disease that affects livestock, wildlife, and humans worldwide; however, its relative impacts on these populations remain underappreciated. Feral swine (Sus scrofa) are relatively resistant to developing anthrax, and past serosurveys hav...

  • Article
  • Open Access
7 Citations
2,627 Views
15 Pages

Characterization and Control of Dendrobium officinale Bud Blight Disease

  • Jinzhao Zhang,
  • Haodong Sha,
  • Weiliang Chen and
  • Bizeng Mao

Dendrobium officinale is an important traditional Chinese medicine (TCM). A disease causing bud blight in D. officinale appeared in 2021 in Yueqing city, Zhejiang Province, China. In this paper, 127 isolates were obtained from 61 plants. The isolates...

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Pathogens - ISSN 2076-0817