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Diagnostics, Volume 9, Issue 1

March 2019 - 35 articles

Cover Story: The field of wound care is challenged by bacteria harboured within the wounds, which delay wound healing and are challenging for clinicians to detect. A handheld fluorescence imaging device, novel to the wound care space, is able to visualize and localize regions of concerning bacterial loads based on their unique red- and cyan-coloured fluorescence signals. In the fluorescence image on the cover of this issue, bacteria within the wound uniquely fluoresced red and pink when imaged with the device, facilitating point-of-care diagnosis of bacterial presence at moderate to heavy loads. This tutorial provides clinicians with information and examples of typical fluorescence signals from tissue and bacteria seen in wounds. View this paper.
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Articles (35)

  • Article
  • Open Access
7 Citations
5,573 Views
13 Pages

Very Early Response Evaluation by PET/MR in Patients with Lung Cancer—Timing and Feasibility

  • Natasha Hemicke Langer,
  • Seppo W. Langer,
  • Helle Hjorth Johannesen,
  • Adam Espe Hansen,
  • Junia Costa,
  • Thomas Levin Klausen,
  • Julie Forman,
  • Anders Olin,
  • Sine Hvid Rasmussen and
  • Jens Benn Sørensen
  • + 3 authors

Purpose: With the increasing number of therapy options available for patients with lung cancer, early response evaluation is needed. We performed this pilot study to assess the feasibility of early, repeated Positron emission tomography-magnetic reso...

  • Article
  • Open Access
45 Citations
6,880 Views
9 Pages

Active Matrix Metalloproteinase-8 Point-of-Care (PoC)/Chairside Mouthrinse Test vs. Bleeding on Probing in Diagnosing Subclinical Periodontitis in Adolescents

  • Ismo T. Räisänen,
  • Timo Sorsa,
  • Gerrit-Jan van der Schoor,
  • Taina Tervahartiala,
  • Peter van der Schoor,
  • Dirk-Rolf Gieselmann and
  • Anna Maria Heikkinen

This cross-sectional study compares the effectiveness of an active MMP-8 (aMMP-8) point-of-care (PoC)/chairside mouthrinse test to the conventional bleeding on probing (BOP) (cutoff 20%) test in detecting subclinical periodontitis/pre-periodontitis i...

  • Article
  • Open Access
21 Citations
6,842 Views
10 Pages

Autism spectrum disorder (ASD) is a neurological and developmental disorder whose late diagnosis is based on subjective tests. In seeking for earlier diagnosis, we aimed to find objective biomarkers via analysis of resting-state functional MRI (rs-fM...

  • Article
  • Open Access
28 Citations
10,497 Views
13 Pages

Predicting Pulmonary Function Testing from Quantified Computed Tomography Using Machine Learning Algorithms in Patients with COPD

  • Joshua Gawlitza,
  • Timo Sturm,
  • Kai Spohrer,
  • Thomas Henzler,
  • Ibrahim Akin,
  • Stefan Schönberg,
  • Martin Borggrefe,
  • Holger Haubenreisser and
  • Frederik Trinkmann

Introduction: Quantitative computed tomography (qCT) is an emergent technique for diagnostics and research in patients with chronic obstructive pulmonary disease (COPD). qCT parameters demonstrate a correlation with pulmonary function tests and sympt...

  • Review
  • Open Access
45 Citations
11,734 Views
16 Pages

Diabetes technology has continually evolved over the years to improve quality of life and ease of care for affected patients. Frequent blood glucose (BG) checks and multiple daily insulin injections have become standard of care in Type 1 diabetes (T1...

  • Review
  • Open Access
117 Citations
11,587 Views
11 Pages

The aim of this study was to provide an overview of the literature available on machine learning (ML) algorithms applied to the Lung Image Database Consortium Image Collection (LIDC-IDRI) database as a tool for the optimization of detecting lung nodu...

  • Review
  • Open Access
37 Citations
8,780 Views
10 Pages

Roles of ERCP in the Early Diagnosis of Pancreatic Cancer

  • Keiji Hanada,
  • Tomoyuki Minami,
  • Akinori Shimizu,
  • Motomitsu Fukuhara,
  • Shigeki Yano,
  • Kenji Sasaki,
  • Masanori Koda,
  • Kayo Sugiyama,
  • Shuji Yonehara and
  • Akio Yanagisawa

It has been reported that endoscopic retrograde cholangiopancreatography (ERCP) is of value in evaluating precise pancreatograms of the pancreatic duct (PD). Recently, institutions have tended to perform magnetic resonance cholangiopancreatography (M...

  • Article
  • Open Access
25 Citations
5,340 Views
12 Pages

Background: Vascular diseases are multifactorial and several risk factors may have synergetic effect on the global vascular risk. Among patients with diabetes, we investigated whether vitamin B6 species differ according to global cardiovascular risk....

  • Article
  • Open Access
5,590 Views
11 Pages

In regenerative medicine, evaluation of bone mineral density using a microfocus X-ray generator could eventually be used to determine the degree of bone tissue regeneration. To evaluate bone mineral density against regenerated bone material, two low-...

  • Article
  • Open Access
49 Citations
20,636 Views
13 Pages

Considerable controversy has existed with efforts to assess post-exertional malaise (PEM), which is one of the defining features of myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS). While a number of self-report questionnaires have b...

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Diagnostics - ISSN 2075-4418