Table of Contents
Diagnostics, Volume 10, Issue 4 (April 2020) – 75 articles
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Cover Story (view full-size image) The differential diagnosis in Interstitial Lung Diseases (ILDs) can be challenging due to the large [...] Read more. The differential diagnosis in Interstitial Lung Diseases (ILDs) can be challenging due to the large number of possible causes. Autoimmune Diseases (ADs) are a common cause of ILD, not always easy to recognize. Rheumatologists are rarely involved in diagnostic Multi-Disciplinary Teams for ILD and patients generally refer to pulmonologists for their symptoms. High-Resolution Computed Tomography can help the diagnosis in presence of Nonspecific Interstitial Pneumonia pattern, but ADs are able to produce all possible ILD patterns, alone or even combined. In this scenario, auto-antibodies can have a great value, although patients can be seronegative, and myositis-specific antibodies are still not widely diffused in clinical practice. Moreover, systemic symptoms and signs are frequently nuanced and may not be noticed by non-trained physicians. Hereby, we discuss elements suggestive for ADs-ILD, reporting our methodology. For the presentation, we chose a picture of “ILD-hands”, because hands