Table of Contents
Diagnostics, Volume 10, Issue 3 (March 2020) – 53 articles
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Cover Story (view full-size image) 18F-FLT PET/CT has been used in response assessment of neoadjuvant chemotherapy in soft-tissue [...] Read more. 18F-FLT PET/CT has been used in response assessment of neoadjuvant chemotherapy in soft-tissue sarcomas, but never in early response to systematically targeted therapies. In this pilot work, 18F-FLT PET/CT was studied for early response evaluation in patients with sarcomas receiving two new therapies: mdm2-inhibitor or c-met-inhibitor. An early response was observed within 1–4 weeks in patients who responded (8 out of 15), and new response criteria for these patients could be developed. View this paper.