Table of Contents
Diagnostics, Volume 10, Issue 5 (May 2020) – 88 articles
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Cover Story (view full-size image) Magnetic lateral flow immunoassays (LFIAs) are emerging as powerful biosensors for diagnostics. On [...] Read more. Magnetic lateral flow immunoassays (LFIAs) are emerging as powerful biosensors for diagnostics. On one hand, magnetic nanoparticles (MNPs) used as labels can be quantified by external devices, allowing the development of simple tests with quantitative capability. They can be used with optical and magnetic sensing, and they can also be detected by the naked eye. On the other hand, MNPs are used for immunomagnetic separation, enabling sensitivity and selectivity improvements. On this basis, magnetic LFIAs have been recently used for the determination of biomarkers, pathogens, toxins, allergens and drugs. The limits of detection reported were better than those achieved with conventional labels (gold and latex nanoparticles). In this paper, we have analysed the current knowledge on magnetic lateral flow immunoassays, with a special focus on the type of magnetic nanoparticles used and magnetic principles for transduction. View this paper