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Life, Volume 13, Issue 7

2023 July - 196 articles

Cover Story: Although immunotherapy has proved to be a very efficient therapeutic strategy for many types of tumors, the results for pancreatic cancer (PC) have been very poor. Indeed, chemotherapy remains the standard treatment for this tumor in the advanced stage. The main reasons for the poor efficacy of immunotherapy probably lie in the peculiar features of the pancreatic tumor microenvironment in comparison with other malignancies. In addition, the biomarkers usually evaluated to define immunotherapy efficacy in other cancers appear to be useless in PC. This review aims to describe the main features of the pancreatic tumor microenvironment from an immunological point of view and to summarize the current data on immunotherapy efficacy and immune biomarkers in PC. View this paper
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Articles (196)

  • Article
  • Open Access
5 Citations
4,069 Views
20 Pages

Leaf Morphological and Epidermal Traits Variability along Environmental Gradients in Ten Natural Populations of Pistacia lentiscus

  • Abdelghafour Doghbage,
  • Safia Belhadj,
  • Fathi Abdellatif Belhouadjeb,
  • Hassen Boukerker,
  • Jean Philippe Mevy,
  • Thierry Gauquelin,
  • Alain Tonetto,
  • Saifi Merdas,
  • Bakria Touati and
  • Walid Soufan
  • + 4 authors

24 July 2023

The species belonging to the genus Pistacia possess ecological, economic, and medicinal value. They show a very high ecological plasticity. This research is a contribution to the study of the intraspecific diversity and variability of 10 populations...

  • Review
  • Open Access
11 Citations
5,864 Views
12 Pages

24 July 2023

This review article discusses the clinical significance of intraoperative neurophysiological monitoring (IONM), provides recommendations for monitoring protocols, and considers the interpretation of results in microvascular decompression (MVD) for he...

  • Article
  • Open Access
2 Citations
3,847 Views
10 Pages

Bacterial Contamination in Total Joint Replacement: Should We Change into a New Set of Clean Scrub Suits Whenever Entering the Operating Room?

  • Toshiyuki Tateiwa,
  • Yasuhito Takahashi,
  • Tsunehito Ishida,
  • Toshinori Masaoka,
  • Takaaki Shishido and
  • Kengo Yamamoto

24 July 2023

Background: The aims of this study are as follows: (1) to investigate the level and probability of bacterial contamination on scrub suits over time for medical personnel working inside and/or outside the operating room (OR) area; (2) to discuss the p...

  • Review
  • Open Access
4 Citations
3,655 Views
13 Pages

Cerebral Vasomotor Reactivity in COVID-19: A Narrative Review

  • Zahra Ghotbi,
  • Mehrdad Estakhr,
  • Melika Hosseini and
  • Reza Bavarsad Shahripour

24 July 2023

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the respiratory system but can also lead to neurological complications. Among COVID-19 patients, the endothelium is considered the Achilles heel. A variety of endothelial...

  • Review
  • Open Access
3 Citations
3,005 Views
18 Pages

24 July 2023

Most human proteins are modified by enzymes that act on the α-amino group of a newly synthesized polypeptide. Methionine aminopeptidases can remove the initiator methionine and expose the second amino acid for further modification by enzymes responsi...

  • Article
  • Open Access
1 Citations
2,170 Views
11 Pages

Hemostatic Effects of Raloxifene in Ovariectomized Rats

  • Denys Alva-Chavarría,
  • Maribel Soto-Núñez,
  • Edgar Flores-Soto and
  • Ruth Jaimez

23 July 2023

This study aimed to explore the effects of raloxifene (Rx) and estradiol (E2) on prothrombin time (PT), partial thromboplastin time (APTT), coagulation factors (VII, X, XI), and fibrinogen concentrations in rats. Female rats were ovariectomized 11 da...

  • Article
  • Open Access
12 Citations
4,547 Views
14 Pages

Antiviral Potential of Specially Selected Bulgarian Propolis Extracts: In Vitro Activity against Structurally Different Viruses

  • Neli Milenova Vilhelmova-Ilieva,
  • Ivanka Nikolova Nikolova,
  • Nadya Yordanova Nikolova,
  • Zdravka Dimitrova Petrova,
  • Madlena Stephanova Trepechova,
  • Dora Ilieva Holechek,
  • Mina Mihaylova Todorova,
  • Mariyana Georgieva Topuzova,
  • Ivan Georgiev Ivanov and
  • Yulian Dimitrov Tumbarski

23 July 2023

Propolis is a natural mixture of resins, wax, and pollen from plant buds and flowers, enriched with enzymes and bee saliva. It also contains various essential oils, vitamins, mineral salts, trace elements, hormones, and ferments. It has been found th...

  • Article
  • Open Access
3 Citations
2,298 Views
12 Pages

Hypofractionated Post-Prostatectomy Radiotherapy in 16 Fractions: A Single-Institution Outcome

  • Pavol Dubinsky,
  • Vladimir Vojtek,
  • Katarina Belanova,
  • Natalia Janickova,
  • Noemi Balazova and
  • Zuzana Tomkova

23 July 2023

Background: The optimal hypofractionated schedule of post-prostatectomy radiotherapy remains to be established. We evaluated treatment outcomes and toxicity of moderately hypofractionated post-prostatectomy radiotherapy in 16 daily fractions delivere...

  • Article
  • Open Access
3 Citations
3,410 Views
17 Pages

Histopathological Pulmonary Lesions in 1st-Day Newborn Piglets Derived from PRRSV-1 MLV Vaccinated Sows at the Last Stage of Gestation

  • Georgios I. Papakonstantinou,
  • Dimitra Psalla,
  • Aris Pourlis,
  • Ioanna Stylianaki,
  • Labrini V. Athanasiou,
  • Eleni Tzika,
  • Eleftherios Meletis,
  • Polychronis Kostoulas,
  • George Maragkakis and
  • Vasileios G. Papatsiros
  • + 2 authors

23 July 2023

Modified live virus (MLV) vaccines for the control of porcine respiratory and reproductive syndrome virus (PRRSV) have been associated with the vertical and horizontal transmission of vaccine viruses. The present study aimed to describe pathological...

  • Review
  • Open Access
7 Citations
3,182 Views
12 Pages

22 July 2023

Metabolic syndrome (MetS) imposes a substantial burden on the healthcare systems and economies of countries and is a major public health concern worldwide. MetS is mainly caused by an imbalance between calorie intake and energy expenditure; however,...

  • Article
  • Open Access
4 Citations
2,621 Views
12 Pages

Suppression of Metastatic Ovarian Cancer Cells by Bepridil, a Calcium Channel Blocker

  • Songzi Zhang,
  • Dokyeong Kim,
  • Minyoung Park,
  • Jing Hu Yin,
  • Junseong Park and
  • Yeun-Jun Chung

22 July 2023

Although surgery followed by platinum-based therapy is effective as a standard treatment in the early stages of ovarian cancer, the majority of cases are diagnosed at advanced stages, leading to poor prognosis. Thus, the identification of novel thera...

  • Article
  • Open Access
1 Citations
4,738 Views
11 Pages

21 July 2023

Background: The passive leg-raising (PLR) test was developed to predict fluid responsiveness and reduce fluid overload. However, the hemodynamic response of healthy individuals to the PLR test and how it changes during the day, between the morning an...

  • Review
  • Open Access
4 Citations
2,928 Views
13 Pages

21 July 2023

Due to technological advancements during the past 20 years, transcatheter aortic valve replacements (TAVRs) have significantly improved the treatment of symptomatic and severe aortic stenosis, significantly improving patient outcomes. The continuous...

  • Article
  • Open Access
8 Citations
2,236 Views
20 Pages

21 July 2023

Plants with high biomass adapted to conditions of increased moisture and with significant salt tolerance appear to be particularly attractive candidates for phytoremediation studies. The aim of the present study was to examine the tolerance of Rumex ...

  • Review
  • Open Access
10 Citations
5,684 Views
18 Pages

Lung Transplantation in a New Era in the Field of Cystic Fibrosis

  • Wei Huang,
  • Alexander T. Smith,
  • Maksim Korotun,
  • Aldo Iacono and
  • Janice Wang

21 July 2023

Lung transplantation for people with cystic fibrosis (PwCF) is a critical therapeutic option, in a disease without a cure to this day, and its overall success in this population is evident. The medical advancements in knowledge, treatment, and clinic...

  • Article
  • Open Access
5 Citations
2,714 Views
13 Pages

Decreased HDL-C Levels as a Predictor of Organ Failure in Acute Pancreatitis in the Emergency Department

  • Ana Rocío Venegas-Tamayo,
  • Olga Mariel Peña-Veites,
  • Martha Alicia Hernández-González and
  • Cornelio Barrientos-Alvarado

21 July 2023

High-density lipoprotein cholesterol (HDL-C) is reported as a biomarker of systemic inflammation and multi-organ failure (MOF), which has been rarely investigated in acute pancreatitis (AP), a frequent condition in the emergency department (ED). The...

  • Review
  • Open Access
4 Citations
3,364 Views
11 Pages

Golimumab for Polyarticular Juvenile Idiopathic Arthritis and Psoriatic Arthritis: Pharmacologic and Clinical Considerations

  • Sydney Moore McIntosh,
  • Christian Kerut,
  • Payton P. Hollenshead,
  • Dorothy H. Askins,
  • Kasra Mansourian,
  • Zachary R. Palowsky,
  • Varsha Allampalli,
  • Shahab Ahmadzadeh,
  • Sahar Shekoohi and
  • Alan D. Kaye

21 July 2023

Psoriatic arthritis is a chronic debilitating autoimmune condition, and when diagnosed in patients before the age of eighteen, it is considered pediatric polyarticular juvenile idiopathic arthritis. Monoarticular or polyarticular psoriatic arthritis...

  • Article
  • Open Access
3 Citations
2,616 Views
24 Pages

21 July 2023

Breast cancer continuously poses serious clinical challenges to human health due to its intrinsic heterogenicity and evolving drug resistance. Recently, increasing evidence has shown that pyroptosis, known as a programmed and inflammatory form of cel...

  • Review
  • Open Access
28 Citations
5,776 Views
16 Pages

The Role of Renin–Angiotensin System in Diabetic Cardiomyopathy: A Narrative Review

  • João Pedro Thimotheo Batista,
  • André Oliveira Vilela de Faria,
  • Thomas Felipe Silva Ribeiro and
  • Ana Cristina Simões e Silva

21 July 2023

Diabetic cardiomyopathy refers to myocardial dysfunction in type 2 diabetes, but without the traditional cardiovascular risk factors or overt clinical atherosclerosis and valvular disease. The activation of the renin–angiotensin system (RAS), o...

  • Article
  • Open Access
2 Citations
2,851 Views
12 Pages

Cerebral Perfusion Pressure-Guided Therapy in Patients with Subarachnoid Haemorrhage—A Retrospective Analysis

  • Agata Gradys,
  • Jakub Szrama,
  • Zsolt Molnar,
  • Przemysław Guzik and
  • Krzysztof Kusza

21 July 2023

Background: Prevention and treatment of haemodynamic instability and increased intracranial pressure (ICP) in patients with subarachnoid haemorrhage (SAH) is vital. This study aimed to evaluate the effects of protocolised cerebral perfusion pressure...

  • Article
  • Open Access
5 Citations
1,995 Views
10 Pages

Genetic Structure and Biodiversity in Wild Centropomus parallelus and in Wild and Recently Domesticated Centropomus undecimallis Populations

  • Marcos Edgar Herkenhoff,
  • Miklos Maximiliano Bajay and
  • Carlos André da Veiga Lima-Rosa Costamilan

20 July 2023

Centropomus undecimalis (common snook) and Centropomus parallelus (fat snook) have a wide distribution from southern Florida to southern Brazil. Due to their value as a food source, these species have been heavily exploited through predatory fishing,...

  • Article
  • Open Access
5 Citations
3,232 Views
12 Pages

20 July 2023

(1) Background: bridging revascularization therapy is now the standard of care in patients with ischemic stroke due to large vessel occlusion. This study aimed to determine the frequency of symptomatic intracranial hemorrhage (sICH) related to this t...

  • Article
  • Open Access
6 Citations
2,080 Views
15 Pages

Assessment of the Health of Soils Contaminated with Ag, Bi, Tl, and Te by the Intensity of Microbiological Activity

  • Tatiana Minnikova,
  • Sergei Kolesnikov,
  • Dmitry Khoroshaev,
  • Natalia Tsepina,
  • Natalia Evstegneeva and
  • Alena Timoshenko

20 July 2023

Soil health is the basis of ecological and food security for humanity. Among the informative indicators of soil health are microbiological indicators based on the intensity of the carbon dioxide release from the soil. The reaction of the microbial co...

  • Review
  • Open Access
36 Citations
12,517 Views
18 Pages

Pediatric Obesity: Complications and Current Day Management

  • Mary Ellen Vajravelu,
  • Emir Tas and
  • Silva Arslanian

20 July 2023

Obesity affects approximately 1 in 5 youth globally and increases the risk of complications during adolescence and young adulthood, including type 2 diabetes, dyslipidemia, hypertension, non-alcoholic fatty liver disease, obstructive sleep apnea, and...

  • Article
  • Open Access
2 Citations
1,901 Views
11 Pages

Homoarginine Associates with Carotid Intima-Media Thickness and Atrial Fibrillation and Predicts Adverse Events after Stroke

  • Laura Schwieren,
  • Märit Jensen,
  • Robert Schulz,
  • Susanne Lezius,
  • Elena Laxy,
  • Magalie Milatz,
  • Götz Thomalla,
  • Rainer Böger,
  • Christian Gerloff and
  • Chi-un Choe
  • + 2 authors

20 July 2023

Homoarginine is associated with cardio- and cerebrovascular morbidity and mortality. However, the underlying pathomechanisms remain elusive. Here, we evaluated the association of homoarginine with adverse events (i.e., death, stroke, and myocardial i...

  • Review
  • Open Access
13 Citations
14,698 Views
68 Pages

19 July 2023

The Latin word lupus, meaning wolf, was in the medical literature prior to the 1200s to describe skin lesions that devour flesh, and the resources available to physicians to help people were limited. The present text reviews the ethnobotanical and ph...

  • Article
  • Open Access
6 Citations
3,029 Views
22 Pages

19 July 2023

Structural atherosclerosis, as evaluated by carotid intima-media thickness (CIMT), is reported to be positively associated with hypertension. However, angiogenesis, which plays an important role in the progression of structural atherosclerosis, preve...

  • Systematic Review
  • Open Access
2,557 Views
21 Pages

The Role of Blood Oxygen Level Dependent Signal Variability in Pediatric Neuroscience: A Systematic Review

  • Michael F. Dinatolo,
  • Daiana Roxana Pur,
  • Roy Eagleson and
  • Sandrine de Ribaupierre

19 July 2023

Background: As pediatric BOLD Signal Variability (SV) analysis is relatively novel, there is a need to provide a foundational framework that gives researchers an entry point into engaging with the topic. This begins with clarifying the definition of...

  • Case Report
  • Open Access
3 Citations
2,267 Views
8 Pages

Radiotherapy-Induced Atrial Myxoma: A Case Report and Literature Review

  • Walid Shalata,
  • Ismaell Massalha,
  • Shlomo Yaron Ishay,
  • Elena Chernomordikova,
  • Ashraf Abu Jama,
  • Keren Rouvinov,
  • Yulia Dudnik and
  • Alexander Yakobson

19 July 2023

In this particular case study, we present a 66-year-old male who was diagnosed with an atrial myxoma eight years after receiving treatment for non-small cell lung cancer. The patient underwent chemo-radiotherapy (mediastinal area) in 2012 to address...

  • Article
  • Open Access
30 Citations
3,359 Views
14 Pages

Evaluation of Antioxidant Activity, Cytotoxicity, and Genotoxicity of Ptychotis verticillata Essential Oil: Towards Novel Breast Cancer Therapeutics

  • Mohamed Taibi,
  • Amine Elbouzidi,
  • Sabir Ouahhoud,
  • El Hassania Loukili,
  • Douâae Ou-Yahya,
  • Safae Ouahabi,
  • Ali S. Alqahtani,
  • Omar M. Noman,
  • Mohamed Addi and
  • Khalid Chaabane
  • + 4 authors

19 July 2023

Breast cancer is a disease characterized by the uncontrolled proliferation of malignant cells in breast tissue, and oxidative stress activated by an accumulation of reactive oxygen species (ROS) is associated with its development and progression. Ess...

  • Article
  • Open Access
6 Citations
2,880 Views
19 Pages

Cuproptosis and Immune-Related Gene Signature Predicts Immunotherapy Response and Prognosis in Lung Adenocarcinoma

  • Zihao Sun,
  • Xiujing Chen,
  • Xiaoning Huang,
  • Yanfen Wu,
  • Lijuan Shao,
  • Suna Zhou,
  • Zhu Zheng,
  • Yiguang Lin and
  • Size Chen

19 July 2023

Cuproptosis and associated immune-related genes (IRG) have been implicated in tumorigenesis and tumor progression. However, their effects on lung adenocarcinoma (LUAD) have not been elucidated. Therefore, we investigated the impact of cuproptosis-ass...

  • Article
  • Open Access
7 Citations
2,837 Views
12 Pages

Risk Factors and Outcomes of Children with Congenital Heart Disease on Extracorporeal Membrane Oxygenation—A Ten-Year Single-Center Report

  • Antonio Amodeo,
  • Milena Stojanovic,
  • Tugba Erdil,
  • Hitendu Dave,
  • Robert Cesnjevar,
  • Sebastian Paal,
  • Oliver Kretschmar and
  • Martin Schweiger

19 July 2023

For children born with congenital heart defects (CHDs), extracorporeal life support may be necessary. This retrospective single-center study aimed to investigate the outcomes of children with CHDs on extracorporeal membrane oxygenation (ECMO), focusi...

  • Article
  • Open Access
5 Citations
2,441 Views
13 Pages

Sigma-1 Receptor Activation Is Protective against TGFβ2-Induced Extracellular Matrix Changes in Human Trabecular Meshwork Cells

  • Minh Ngoc Tran,
  • Timea Medveczki,
  • Balazs Besztercei,
  • Gyorgy Torok,
  • Attila J. Szabo,
  • Xavier Gasull,
  • Illes Kovacs,
  • Andrea Fekete and
  • Judit Hodrea

19 July 2023

The trabecular meshwork (TM) route is the principal outflow egress of the aqueous humor. Actin cytoskeletal remodeling in the TM and extracellular matrix (ECM) deposition increase TM stiffness, outflow resistance, and elevate intraocular pressure (IO...

  • Review
  • Open Access
30 Citations
24,238 Views
15 Pages

Dual Antiplatelet Therapy: A Concise Review for Clinicians

  • Hafeez Ul Hassan Virk,
  • Johao Escobar,
  • Mario Rodriguez,
  • Eric R. Bates,
  • Umair Khalid,
  • Hani Jneid,
  • Yochai Birnbaum,
  • Glenn N. Levine,
  • Sidney C. Smith and
  • Chayakrit Krittanawong

18 July 2023

Dual antiplatelet therapy (DAPT) combines two antiplatelet agents to decrease the risk of thrombotic complications associated with atherosclerotic cardiovascular diseases. Emerging data about the duration of DAPT is being published continuously. New...

  • Article
  • Open Access
9 Citations
3,235 Views
13 Pages

18 July 2023

Simple sequence repeats (SSRs) are highly versatile markers in genetic diversity analysis and plant breeding, making them widely applicable. They hold potential in lentil (Lens culinaris) breeding for genetic diversity analysis, marker-assisted selec...

  • Article
  • Open Access
1 Citations
2,079 Views
21 Pages

Enhanced Resolution of Neutron Autoradiography with UV-C Sensitization to Study Boron Microdistribution in Animal Models

  • Agustina Mariana Portu,
  • María Sol Espain,
  • Silvia Inés Thorp,
  • Verónica Andrea Trivillin,
  • Paula Curotto,
  • Andrea Monti Hughes,
  • Emiliano César Cayetano Pozzi,
  • Marcela Alejandra Garabalino,
  • Mónica Alejandra Palmieri and
  • Gisela Saint Martin
  • + 3 authors

18 July 2023

The assessment of boron microdistribution is essential to evaluate the suitability of boron neutron capture therapy (BNCT) in different biological models. In our laboratory, we have reported a methodology to produce cell imprints on polycarbonate thr...

  • Review
  • Open Access
9 Citations
7,459 Views
11 Pages

SARS-CoV-2 Infection—A Trigger Factor for Telogen Effluvium: Review of the Literature with a Case-Based Guidance for Clinical Evaluation

  • Gabriela Mariana Iancu,
  • Estera Molnar,
  • Loredana Ungureanu,
  • Simona Corina Șenilă,
  • Adrian Hașegan and
  • Maria Rotaru

18 July 2023

Telogen effluvium post-COVID-19 is a condition characterized by the diffuse and reversible loss of scalp hair in the period following infection with SARS-CoV-2, and it is currently the second cause of alopecia in women. In the context of the COVID-19...

  • Review
  • Open Access
6 Citations
2,375 Views
13 Pages

Contributing Role of High Mobility Group Box 1 Signaling in Oral Cancer Development and Therapy

  • Grigorios Plemmenos,
  • Valentini Tzimogianni,
  • Christina Fili and
  • Christina Piperi

18 July 2023

Oral squamous cell carcinoma (OSCC) is the most frequent type of oral cancer of multifactorial origin, characterized by histological and clinical manifestations. To date, there are no specific biomarkers or treatment modalities available to efficient...

  • Article
  • Open Access
9 Citations
2,686 Views
11 Pages

Toxoplasma gondii Infection in Patients with Cardiovascular Diseases from Western Romania: A Case–Control Study

  • Angela Dragomir,
  • Maria Alina Lupu,
  • Rodica Lighezan,
  • Ana Alexandra Paduraru and
  • Tudor Rares Olariu

17 July 2023

(1) Background: Toxoplasma gondii infects approximately one third of the world’s human population. The seroepidemiology of T. gondii in cardiovascular patients is poorly discussed in the existing literature. We aimed to evaluate, for the first...

  • Article
  • Open Access
7 Citations
6,034 Views
12 Pages

Pilot Study: The Relationship between Foot Posture and Movement Quality in Non-Professional Male Football Players

  • José Algaba-Del-Castillo,
  • Aurora Castro-Méndez,
  • Ana Juana Pérez-Belloso,
  • José Gabriel Garrido-Barragán,
  • Alberto Aguilar Sánchez and
  • Manuel Coheña-Jiménez

17 July 2023

(1) Background: This study focusses on establishing the relationship between quality of movement (based on the functional movement screen, or FMS) and foot posture (based on the foot posture index, or FPI-6). We hypothesised that a poor FMS test scor...

  • Review
  • Open Access
26 Citations
10,158 Views
16 Pages

Molecular Insights into Royal Jelly Anti-Inflammatory Properties and Related Diseases

  • Lilla Bagameri,
  • Sara Botezan,
  • Otilia Bobis,
  • Victorita Bonta and
  • Daniel Severus Dezmirean

17 July 2023

Royal jelly (RJ), a highly nutritious natural product, has gained recognition for its remarkable health-promoting properties, leading to its widespread use in the pharmaceutical, food, and cosmetic industries. Extensive investigations have revealed t...

  • Article
  • Open Access
5 Citations
2,956 Views
11 Pages

The Association of Body Mass Index with COVID-19 Complications and Survival Rate at a Tertiary Hospital

  • Salma AlBahrani,
  • Thekra N. Al-Maqati,
  • Yaser A. Al Naam,
  • Jaber S. Alqahtani,
  • Abdullah S. Alqahtani,
  • Saad AlRabeeah,
  • Abdulelah M. Aldhahir,
  • Faisal Alkhalaf,
  • Hind R. Alzuraiq and
  • Rawan M. Maawadh
  • + 4 authors

16 July 2023

A high body mass index (BMI) is a known risk factor for coronavirus infection in hospitalized patients. Our study examined the association between BMI and complications and the survival rate among COVID-19 patients. This retrospective analysis used d...

  • Article
  • Open Access
6 Citations
2,443 Views
12 Pages

Right Ventricular Myocardial Involvement in Anderson–Fabry Disease at Diagnosis: Evaluation with Three-Dimensional Strain Imaging

  • Martina Pucci,
  • Velia Iadevaia,
  • Vittoria Gammaldi,
  • Adelaide Iervolino,
  • Luca Maria Capece,
  • Domenico Sciascia,
  • Vittoria Cuomo,
  • Marina Iacono,
  • Daniele Paoletta and
  • Roberta Esposito
  • + 1 author

16 July 2023

Background: Right ventricular (RV) involvement in Anderson–Fabry disease (AFD) is well known in the advanced stages of the disease RV hypertrophies, but little is known about the early involvement. The aim of our study was to assess RV function...

  • Article
  • Open Access
9 Citations
2,307 Views
15 Pages

Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasm of the Pancreas

  • Jasmina Kuvendjiska,
  • Felix Müller,
  • Peter Bronsert,
  • Sylvia Timme-Bronsert,
  • Stefan Fichtner-Feigl and
  • Birte Kulemann

15 July 2023

Intraductal papillary mucinous neoplasm (IPMN) is the most common pancreatic cyst and a precursor of pancreatic cancer (PDAC). Since PDAC has a devastatingly high mortality rate, the early diagnosis and treatment of any precursor lesion are rational....

  • Article
  • Open Access
3 Citations
4,314 Views
10 Pages

Analysis of Refractive Errors in a Large Italian Cohort of Pediatric Subjects Post the COVID-19 Pandemic

  • Michele Lanza,
  • Adriano Ruggiero,
  • Matteo Ruggiero,
  • Clemente Maria Iodice and
  • Francesca Simonelli

15 July 2023

Background: The prevalence of refractive errors has sharply risen over recent decades. Despite the established role of genetics in the onset and progression of such conditions, the environment was also shown to play a pivotal role. Indeed, the COVID-...

  • Article
  • Open Access
3 Citations
2,186 Views
13 Pages

Mitral Annular Calcification and Thromboembolic Risk

  • Paula Cristina Morariu,
  • Daniela Maria Tanase,
  • Diana Elena Iov,
  • Oana Sîrbu,
  • Alexandru Florinel Oancea,
  • Cornel Gabriel Mircea,
  • Cristina Petronela Chiriac,
  • Genoveva Livia Baroi,
  • Ionela-Daniela Morariu and
  • Mariana Floria
  • + 2 authors

15 July 2023

Thromboembolic (TE) risk scores used for atrial fibrillation (AF) patients do not include mitral annular calcification (MAC) as a potential indicator of vascular disease. This research evaluated the correlation between MAC and TE risk scores (CHADS2...

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Life - ISSN 2075-1729