Polymer-coated controlled-release fertilizers’ (CRFs) unique nutrient release mechanism has the potential to mitigate the leaching of mobile soil nutrients, such as nitrate-nitrogen (NO
3-N). The study aimed to evaluate the capacity of a polymer-coated CRFs to maintain maize (
Zea mays L.) crop growth/health indicators and production goals, while reducing NO
3-N leaching risks compared to conventional (CONV) fertilizers in North Florida. Four CRF rates (168, 224, 280, 336 kg N ha
−1) were assessed against a no nitrogen (N) application and the current University of Florida Institute for Food and Agricultural Sciences (UF/IFAS) recommended CONV (269 kg N ha
−1) fertilizer rate. All CRF treatments, even the lowest CRF rate (168 kg N ha
−1), produced yields, leaf tissue N concentrations, plant heights, aboveground biomasses (AGB), and leaf area index (LAI) significantly (
p < 0.05) greater than or similar to the CONV fertilizer treatment. Additionally, in 2022, the CONV fertilizer treatment resulted in increases in late-season movement of soil NO
3-N into highly leachable areas of the soil profile (60–120 cm), while none of the CRF treatments did. However, back-to-back leaching rainfall (>76.2 mm over three days) events in the 2023 growing season masked any trends as NO
3-N was likely completely flushed from the system. The results of this two-year study suggest that polymer-coated CRFs can achieve desirable crop growth, crop health, and production goals, while also having the potential to reduce the late-season leaching potential of NO
3-N; however, more research is needed to fully capture and quantify the movement of NO
3-N through the soil profile. Correlation and Principal Component Analysis (PCA) revealed that CRF performance was significantly influenced by environmental factors such as rainfall and temperature. In 2022, temperature-driven nitrogen release aligned with crop uptake, supporting higher yields and minimizing NO
3-N movement. In 2023, however, rainfall-driven variability led to an increase in NO
3-N leaching and masked the benefits of CRF treatments. These analyses provided critical insights into the relationships between environmental factors and CRF performance, emphasizing the importance of adaptive fertilizer management under varying climatic conditions.
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