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Nutrients, Volume 17, Issue 11

June-1 2025 - 197 articles

Cover Story: Ginseng Phytochemicals in Bone Disease Management: From Mechanisms to Therapy: Ginsenosides and polysaccharides from ginseng demonstrate multi-target therapeutic potential against bone-related pathologies. This review synthesizes 2014–2024 evidence on ginseng phytochemicals' anti-osteosarcoma, anti-osteoporotic, and anti-osteoarthritic actions across in vitro, in vivo, and clinical models. In osteosarcoma, they inhibit tumor progression through synergistic pathways and combination strategies. In osteoporosis, these compounds activate osteoblasts and suppress osteoclast activity. In osteoarthritis, ginsenosides reduce inflammation and protect cartilage. We critically analyze molecular mechanisms while addressing bioavailability challenges and model limitations. The work outlines future translational directions for harnessing ginseng's pharmacology in precision bone health interventions. View this paper
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Articles (197)

  • Article
  • Open Access
2 Citations
2,701 Views
16 Pages

5 June 2025

Background: Chronic alcohol intake impairs intestinal function, while L-theanine (LTA) may support intestinal health. However, the protective effects of LTA to chronic alcoholic intestinal injuries remain unclear. Methods: SD rats were administered L...

  • Article
  • Open Access
4,144 Views
14 Pages

5 June 2025

Background: Effective management of postprandial glycemic control is critical for diabetic patients, as elevated postprandial glucose levels can lead to complications such as cardiovascular disease and neuropathy. This study evaluates isomaltulose, a...

  • Article
  • Open Access
1,958 Views
21 Pages

Effect of a Low Glycemic Index/Slow Digesting (LGI/SD) Carbohydrate Product on Maternal Glycemia and Neonatal Body Composition in Obese Pregnant Women: The NIGOHealth Randomized Clinical Trial

  • Mercedes G. Bermúdez,
  • María García-Ricobaraza,
  • José Antonio García-Santos,
  • M. Teresa Segura,
  • Alberto Puertas-Prieto,
  • José Luis Gallo-Vallejo,
  • Carmen Padilla-Vinuesa,
  • Berthold Koletzko,
  • Geraldine E. Baggs and
  • Elena Oliveros
  • + 2 authors

5 June 2025

Background/Objectives: Obesity during pregnancy is strongly related to increased insulin resistance, and subsequent development of metabolic syndrome-like disorders, such as glucose intolerance, pre-eclampsia, as well as preterm birth, and cesarean d...

  • Article
  • Open Access
2,291 Views
15 Pages

5 June 2025

Objectives: The global rise in dementia prevalence is escalating the socioeconomic burden, prompting efforts in prevention and treatment. This study aimed to evaluate the effects of an 8-week oral nutrition supplement (ONS) program with or without a...

  • Review
  • Open Access
3 Citations
18,179 Views
23 Pages

Bacopa monnieri: Preclinical and Clinical Evidence of Neuroactive Effects, Safety of Use and the Search for Improved Bioavailability

  • Anna Gościniak,
  • Anna Stasiłowicz-Krzemień,
  • Marta Szeląg,
  • Jakub Pawlak,
  • Izabela Skiera,
  • Hanna Kwiatkowska,
  • Natasza Nowak,
  • Krzysztof Bernady,
  • Piotr Trzaskoma and
  • Oskar Zimak-Krótkopad
  • + 1 author

5 June 2025

Bacopa monnieri, also known as Brahmi or Waterhyssop, is a plant used in Ayurveda for its memory-enhancing properties and control of blood sugar levels. It contains active compounds such as alkaloids, saponins, and cucurbitacins, which have various b...

  • Review
  • Open Access
1 Citations
2,964 Views
25 Pages

The Association of Food Insecurity and Risk of Mortality: A Systematic Review and Meta-Analysis of Large-Scale Cohorts

  • Cyrus Jalili,
  • Seyedeh Parisa Moosavian,
  • Farhang Hameed Awlqadr,
  • Sanaz Mehrabani,
  • Reza Bagheri,
  • Matin Sedighy,
  • Shirley Hodder,
  • Faramarz Jalili,
  • Mohammad Ali Hojjati Kermani and
  • Maryam Zamir Nasta
  • + 2 authors

5 June 2025

Objectives: Food insecurity (FI) represents a significant global public health issue, yet existing literature presents inconsistent findings regarding its association with mortality risk. This systematic review and meta-analysis aimed to synthesize a...

  • Article
  • Open Access
1 Citations
1,539 Views
14 Pages

First–Second-Trimester Dietary Inflammatory Index and Anemia Risk in the Third Trimester: A Prospective Cohort Study

  • Cong Huang,
  • Zhitan Zhang,
  • Junwei He,
  • Zixin Zhong,
  • Yuxin Ma,
  • Xun Huang,
  • Fan Xia,
  • Hongzhuan Tan,
  • Jing Deng and
  • Mengshi Chen

5 June 2025

Objectives: Dietary conditions are closely related to maternal health. This study aims to investigate the causal relationship between the first–second-trimester Dietary Inflammatory Index (DII) and developing anemia in the third trimester. Meth...

  • Article
  • Open Access
1,095 Views
11 Pages

Association Between Nutritional Status and Early Postoperative Infection Risk in Kidney Transplant Patients

  • Elena González García,
  • Tamara Arroyo,
  • Mercedes Galván,
  • María José Becerra,
  • Margarita Gallego,
  • Israel Mauro,
  • Yanieli Hernández,
  • Almudena Pérez-Torres,
  • María Ovidia López Oliva and
  • María José Santana
  • + 1 author

5 June 2025

Malnutrition is one of the stronger predictors of morbi-mortality in end-stage kidney disease patients. Moreover, malnutrition in hospitalized patients severely affects multiple clinical outcomes, increasing the risk of complications. The Nutritional...

  • Review
  • Open Access
1 Citations
3,522 Views
13 Pages

5 June 2025

Background/Objectives: Obesity pharmacotherapy vastly improved the treatment of the disease of obesity. However, GLP-1 receptor agonists and GIP/GLP-1 dual agonists may lead to nutritional complications, including severe caloric restriction, micronut...

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Nutrients - ISSN 2072-6643Creative Common CC BY license