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Nutrients, Volume 17, Issue 11

June-1 2025 - 197 articles

Cover Story: Ginseng Phytochemicals in Bone Disease Management: From Mechanisms to Therapy: Ginsenosides and polysaccharides from ginseng demonstrate multi-target therapeutic potential against bone-related pathologies. This review synthesizes 2014–2024 evidence on ginseng phytochemicals' anti-osteosarcoma, anti-osteoporotic, and anti-osteoarthritic actions across in vitro, in vivo, and clinical models. In osteosarcoma, they inhibit tumor progression through synergistic pathways and combination strategies. In osteoporosis, these compounds activate osteoblasts and suppress osteoclast activity. In osteoarthritis, ginsenosides reduce inflammation and protect cartilage. We critically analyze molecular mechanisms while addressing bioavailability challenges and model limitations. The work outlines future translational directions for harnessing ginseng's pharmacology in precision bone health interventions. View this paper
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Articles (197)

  • Article
  • Open Access
2,843 Views
19 Pages

Effects of a Balanced Diet and Probiotics on Blood Biomarkers and Gut Microbiota in the Elderly: A Community-Based Intervention Study

  • Junghyun Park,
  • You-Suk Lee,
  • Do-Kyung Lee,
  • Juyong Hong,
  • Seon-Joo Park,
  • Byung Wook Lee,
  • Sang Min Park and
  • Hae-Jeung Lee

4 June 2025

Background/Objectives: Aging is characterized by dysregulation of the immune system. A balanced diet and probiotic intake can play significant roles in preventing aging-related chronic degenerative diseases and promoting immune function in the elderl...

  • Article
  • Open Access
1 Citations
1,245 Views
35 Pages

Nutrient Intake and Plasma and Erythrocyte Content Among Lactating Mothers of Hospitalized Very Preterm Infants: Associations with Human Milk Composition

  • Kristin Keller,
  • Noelia Ureta-Velasco,
  • Diana Escuder-Vieco,
  • José C. E. Serrano,
  • Javier Fontecha,
  • María V. Calvo,
  • Javier Megino-Tello,
  • Carmen R. Pallás-Alonso and
  • Nadia Raquel García-Lara

4 June 2025

Background/Objectives: Lactating mothers have increased nutritional requirements, but nutritional adequacy is difficult to achieve. Additionally, human milk (HM) composition depends on maternal diet. However, the nutritional intake and status of moth...

  • Article
  • Open Access
1,064 Views
16 Pages

4 June 2025

Background/Objectives: The number of chronic kidney disease (CKD) patients is increasing in Japan, and this population is at high risk of death from cardiovascular and cerebrovascular diseases. Therefore, prevention of arteriosclerosis as a common un...

  • Article
  • Open Access
1 Citations
2,566 Views
14 Pages

Dietary and Physical Activity Correlates of Muscle Mass in 60–65-Year-Old Seniors: A Gender-Specific Analysis

  • Bartłomiej K. Sołtysik,
  • Paweł Balicki,
  • Klaudia Kowalczyk,
  • Aleksandra Lutostańska,
  • Julia Dmuchowska,
  • Małgorzata Pigłowska and
  • Tomasz Kostka

4 June 2025

Introduction: Sarcopenia and loss of skeletal muscle mass represent major public health concerns in aging populations. Although both diet and physical activity (PA) are recognized as modifiable determinants of muscle mass, their effects may differ by...

  • Article
  • Open Access
1,747 Views
15 Pages

Impact of Exams on Diet, Physical Activity, and Body Composition in University Students

  • Natalia Mudarra-García,
  • Marina Pérez-Mudarra,
  • Ismael Ortuño-Soriano,
  • Raquel Badía-Iborra,
  • María Jesús Vicente-Galán,
  • Ignacio Zaragoza-García,
  • Fernando Roque-Rojas and
  • Francisco Javier García-Sánchez

4 June 2025

Background: Bad dietary habits and sedentary lifestyles alter body composition, increasing disease risk. Methods: We conducted a prospective, comparative, longitudinal observational study among nursing students from Complutense University of Madrid....

  • Article
  • Open Access
1 Citations
1,693 Views
15 Pages

4 June 2025

Background: Stress adversely affects health behaviors, particularly problematic eating. However, the psychological mechanisms underlying this relationship remain underexplored. This study seeks to examine the mediating role of irrational health belie...

  • Article
  • Open Access
1 Citations
1,065 Views
14 Pages

4 June 2025

Background: Food allergy (FA) is associated with dietary habits, antibiotic use, living environment, and delivery method. Pregnancy and lactation represent critical periods for neonatal immune system development. Methods: This study investigated the...

  • Article
  • Open Access
1 Citations
2,378 Views
20 Pages

4 June 2025

Background/Objectives: Abalone viscera is a discarded seafood by-product that contains a wealth of protein and is a good source of collagen peptides which have proven to have great potential in ameliorating host inflammation. The present study was co...

  • Review
  • Open Access
1 Citations
3,866 Views
20 Pages

Caffeine: A Neuroprotectant and Neurotoxin in Traumatic Brain Injury (TBI)

  • Bharti Sharma,
  • George Agriantonis,
  • Sarah Dawson-Moroz,
  • Rolanda Brown,
  • Whenzdjyny Simon,
  • Danielle Ebelle,
  • Jessica Chapelet,
  • Angie Cardona,
  • Aditi Soni and
  • Maham Siddiqui
  • + 11 authors

4 June 2025

Caffeine is a weak, nonselective adenosine receptor antagonist. At low-to-moderate doses, caffeine has a stimulating effect; however, at higher doses, it can act as a depressant. It can function both as a neuroprotectant and a neurotoxin. In experime...

  • Article
  • Open Access
1 Citations
1,684 Views
21 Pages

The Influence of Competition Day Loads on the Metabolic and Immune Response of Olympic Female Beach Volleyball Athletes: A Sportomics Analysis

  • Renan Muniz-Santos,
  • Flavio Bachini,
  • Adriana Bassini,
  • P. C. B. Alexandre,
  • Igor Jurisica,
  • Vinod Chandran and
  • L. C. Cameron

4 June 2025

Background: Beach volleyball (BVb) is a highly demanding Olympic sport characterized by intense physical activity and unique environmental challenges, including varying weather conditions and sandy, unstable court surfaces. Despite its popularity, th...

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Nutrients - ISSN 2072-6643