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Nutrients, Volume 15, Issue 5

2023 March-1 - 238 articles

Cover Story: The aim of this study was to assess the potential benefits of caffeine intake in protecting against the development of diabetic retinopathy (DR) in subjects with type 2 diabetes (T2D). Furthermore, we tested the effect of topical administration of caffeine on the early stages of DR in an experimental model of DR. In the cross-sectional study, a total of 144 subjects with DR and 147 individuals without DR were assessed. DR was assessed by an experienced ophthalmologist. A validated food frequency questionnaire (FFQ) was administered. In the experimental model, a total of 20 mice were included. One drop (5 μL) of caffeine (5 mg/mL) (n = 10) or vehicle (5 μL PBS, pH 7.4) (n = 10) was randomly administered directly onto the superior corneal surface twice daily for two weeks in each eye. View this paper
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Articles (238)

  • Article
  • Open Access
4 Citations
25,815 Views
12 Pages

6 March 2023

The impact on body weight development is usually analysed by comparing different diet types. Our approach was to change only one component, namely bread, common to most diets. In a single-centre triple-blind randomised controlled trial the effects of...

  • Article
  • Open Access
21 Citations
5,858 Views
13 Pages

6 March 2023

A prospective, randomized, single-center preliminary study was performed in patients with keratoconus stages I–III (Amsler–Krumeich), who received a high rich docosahexaenoic acid (DHA) (1000 mg/day) supplement for 3 months versus untreat...

  • Article
  • Open Access
13 Citations
4,190 Views
15 Pages

Effects of Caprylic Acid and Eicosapentaenoic Acid on Lipids, Inflammatory Levels, and the JAK2/STAT3 Pathway in ABCA1-Deficient Mice and ABCA1 Knock-Down RAW264.7 Cells

  • Xinsheng Zhang,
  • Peng Zhang,
  • Yinghua Liu,
  • Zhao Liu,
  • Qing Xu,
  • Yong Zhang,
  • Lu Liu,
  • Xueyan Yang,
  • Liya Li and
  • Changyong Xue

6 March 2023

Our previous studies have found that caprylic acid (C8:0) can improve blood lipids and reduce inflammation levels and may be related to the upregulation of the p-JAK2/p-STAT3 pathway by ABCA1. This study aims to investigate the effects of C8:0 and ei...

  • Article
  • Open Access
5 Citations
9,021 Views
19 Pages

6 March 2023

This cross-sectional study assessed highly processed food (HPF) consumption and its association with individual characteristics in a nationwide sample of Japanese adults. Eight-day weighed dietary records were obtained from 2742 free-living adults ag...

  • Article
  • Open Access
1 Citations
3,286 Views
13 Pages

Nutritional Intake Differences in Combinations of Carbohydrate-Rich Foods in Pirapó, Republic of Paraguay

  • Yuko Caballero,
  • Konomi Matakawa,
  • Ai Ushiwata,
  • Tomoko Akatsuka and
  • Noriko Sudo

6 March 2023

A national strategy for obesity prevention has been promoted in Paraguay, reflecting the situation where half of adults and 23.4% of children (under 5 years old) are overweight. However, the detailed nutritional intake of the population has not yet b...

  • Article
  • Open Access
17 Citations
6,659 Views
15 Pages

6 March 2023

Background: Malnutrition and increased malnutrition risk are frequently identified in hospitalized adults. The increase in hospitalization rates during the COVID-19 pandemic was accompanied by the documentation of adverse hospitalization outcomes in...

  • Review
  • Open Access
22 Citations
7,818 Views
15 Pages

6 March 2023

Long-term weight loss maintenance is often difficult to achieve. This review analysed qualitative data on self-perceived barriers and facilitators of weight loss and weight loss maintenance among weight loss intervention participants. A literature se...

  • Review
  • Open Access
18 Citations
17,042 Views
16 Pages

6 March 2023

Type 2 diabetes mellitus (T2DM) is a major cause of morbidity and mortality, and it is a major risk factor for the early onset of cardiovascular diseases (CVDs). More than genetics, food, physical activity, walkability, and air pollution are lifestyl...

  • Article
  • Open Access
30 Citations
7,182 Views
22 Pages

Effects of a Synbiotic on Plasma Immune Activity Markers and Short-Chain Fatty Acids in Children and Adults with ADHD—A Randomized Controlled Trial

  • Liu L. Yang,
  • Miranda Stiernborg,
  • Elin Skott,
  • Jingjing Xu,
  • Yujiao Wu,
  • Rikard Landberg,
  • Samsul Arefin,
  • Karolina Kublickiene,
  • Vincent Millischer and
  • Catharina Lavebratt
  • + 3 authors

6 March 2023

Synbiotic 2000, a pre + probiotic, reduced comorbid autistic traits and emotion dysregulation in attention deficit hyperactivity disorder (ADHD) patients. Immune activity and bacteria-derived short-chain fatty acids (SCFAs) are microbiota–gut&n...

  • Article
  • Open Access
1 Citations
3,338 Views
14 Pages

Noninvasive Ventilation and Rapid Enteral Feeding Advances in Preterm Infants—2-Year Follow-Up of the STENA-Cohort

  • Judith Behnke,
  • Vanessa Estreich,
  • Frank Oehmke,
  • Bernd Axel Neubauer,
  • Anita Windhorst and
  • Harald Ehrhardt

6 March 2023

The importance of nutritional supply for somatic growth and neurodevelopmental outcome in very-low-birthweight infants is an established medical strategy for reducing long-term morbidities. Our cohort study on rapid enteral feeding advances using a s...

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Nutrients - ISSN 2072-6643