Metabolic Features and Nutritional Interventions in Chronic Diseases

Dear Colleagues,

A growing body of research indicates an extensive metabolic dysfunction in a spectrum of chronic diseases, comprising aging, cancer and diseases affecting cardiovascular system, liver and kidney. The phenotypes associated with metabolic dysfunction vary depending on disease type and stage. In turn, the altered metabolism drives disease pathology. Consequently, nutritional modulation of metabolic status in chronic disease is widely acknowledged to reduce disease incidence. For instance, tailored nutritional intervention in cancers with altered metabolism determines the improved therapeutic responses. Additionally, counteracting muscle loss and osteoporosis are clinical goals of nutritional support in an aged population. Mechanistically, bioactive nutrients or tailored nutritional regimen modulate metabolism through mitochondrial homeostasis, immuno-regulation, as well as epigenome regulation to impact disease progression.

This Special Issue aims to be an interdisciplinary platform that covers:

1. Characterization of metabolic features and/or nutritional requirement in a certain type of chronic disease;
2. Defining the effects and mechanism of a specific nutrient or nutritional intervention on metabolism;
3. Development of new nutritional strategy that improves disease outcome by altering metabolism.

We invite well-designed research articles, reviews and meta-analyses addressing all the above issues.

Dr. Yongting Luo
Dr. Junjie Luo
Dr. Peng An
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.