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Current Oncology, Volume 30, Issue 5

2023 May - 60 articles

Cover Story: Our retrospective study analyzed the negative impact of COVID-19 on the surgical management of 1331 surgically treated breast cancer cases between 2020 and 2021 in comparison with the previous two years. A reduction of 121 cases (9%) between the pre-pandemic and the pandemic periods was reported. Screenings, diagnosis time and surgical approaches did not show significant differences, while axillary dissections decreased (p < 0.001). The number of 2–3 grade (p = 0.007) and pT 3–4 stage breast cancers surgically treated without neoadjuvant chemotherapy increased (p = 0.03), while luminal B tumors decreased (p = 0.007). The limited reduction in surgical activity for breast cancer treatment in the pandemic was followed by a prompt resumption of surgical activity to levels similar to the pre-pandemic period. View this paper
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Articles (60)

  • Review
  • Open Access
21 Citations
7,603 Views
13 Pages

Immunotherapy in Anal Cancer

  • Natasha Dhawan,
  • Muhammad Z. Afzal and
  • Manik Amin

27 April 2023

The incidence and mortality of squamous cell carcinoma of the anus has been gradually increasing globally over the last few decades. The evolution of different modalities, including immunotherapies, has changed the treatment paradigm of metastatic an...

  • Case Report
  • Open Access
6 Citations
3,985 Views
11 Pages

Immune-Checkpoint Induced Skin Toxicity Masked as Squamous Cell Carcinoma: Case Report on Mimickers of Dermatological Toxicity with PD-1 Inhibition

  • Sze Wah Samuel Chan,
  • Rahul Shukla,
  • Jennifer Ramsay,
  • Elaine McWhirter,
  • Paul Barnfield and
  • Rosalyn A. Juergens

27 April 2023

Background: Immune checkpoint inhibitors (ICI) are increasingly the mainstay of oncology treatment. Immune-related adverse events (irAEs) from ICI therapy differ from cytotoxic adverse events. Cutaneous irAEs are one of the most common irAEs and requ...

  • Review
  • Open Access
7 Citations
7,202 Views
15 Pages

Diagnosis and Treatment of Post-Prostatectomy Lymphedema: What’s New?

  • Lorenzo Maria Giuseppe Bianchi,
  • Giovanni Irmici,
  • Maurizio Cè,
  • Elisa D’Ascoli,
  • Gianmarco Della Pepa,
  • Filippo Di Vita,
  • Omar Casati,
  • Massimo Soresina,
  • Andrea Menozzi and
  • Michaela Cellina
  • + 1 author

25 April 2023

Lymphedema is a chronic progressive disorder that significantly compromises patients’ quality of life. In Western countries, it often results from cancer treatment, as in the case of post-radical prostatectomy lymphedema, where it can affect up...

  • Systematic Review
  • Open Access
10 Citations
3,443 Views
13 Pages

The Role of Preoperative Chemotherapy in the Management of Synchronous Resectable Colorectal Liver Metastases: A Meta-Analysis

  • Kostas Tepelenis,
  • Georgios Pappas-Gogos,
  • Panagiotis Ntellas,
  • Konstantinos Tsimogiannis,
  • Katerina Dadouli,
  • Davide Mauri and
  • Georgios K. Glantzounis

25 April 2023

Background: The indications of preoperative chemotherapy, for initially resectable synchronous colorectal liver metastases, remain controversial. This meta-analysis aimed to assess the efficacy and safety of preoperative chemotherapy in such patients...

  • Article
  • Open Access
10 Citations
4,070 Views
16 Pages

Impact of Fixed-Duration Oral Targeted Therapies on the Economic Burden of Chronic Lymphocytic Leukemia in Canada

  • Jean Lachaine,
  • Kimberly Guinan,
  • Andrew Aw,
  • Versha Banerji,
  • Isabelle Fleury and
  • Carolyn Owen

24 April 2023

Background: Continuous oral targeted therapies (OTT) represent a major economic burden on the Canadian healthcare system, due to their high cost and administration until disease progression/toxicity. The recent introduction of venetoclax-based fixed-...

  • Review
  • Open Access
12 Citations
7,886 Views
46 Pages

Mesenchymal Tumors of the Breast: Fibroblastic/Myofibroblastic Lesions and Other Lesions

  • Riordan Azam,
  • Miralem Mrkonjic,
  • Abha Gupta,
  • Rebecca Gladdy and
  • Andrea M. Covelli

24 April 2023

Mesenchymal breast tumors are a rare and diverse group of tumors that present some of the most challenging cases for multidisciplinary breast cancer teams. As a result of overlapping morphologies and a lack of large-scale studies on these tumors, pra...

  • Communication
  • Open Access
5 Citations
2,349 Views
10 Pages

Evaluation of a Virtual Dance Class for Cancer Patients and Their Partners during the Corona Pandemic—A Real-World Observational Study

  • Jutta Hübner,
  • Ivonne Rudolph,
  • Tobias Wozniak,
  • Ronny Pietsch,
  • Mascha Margolina,
  • Isabel Garcia,
  • Katharina Mayr-Welschlau,
  • Thorsten Schmidt and
  • Christian Keinki

24 April 2023

Background: During the corona pandemic, all courses on physical activity for cancer patients were canceled. The aim of our study was to evaluate the feasibility of switching dancing classes for patients and their partners to online classes. Methods:...

  • Review
  • Open Access
21 Citations
10,514 Views
15 Pages

24 April 2023

Despite high incidence rates and severe complications, the management of xerostomia lacks clinical guidelines. The aim of this overview was to summarize the clinical experience derived from the last 10 years of treatments and prevention using systemi...

  • Case Report
  • Open Access
2 Citations
2,381 Views
10 Pages

Not Waiting to Progress; How the COVID-19 Pandemic Nudged Neoadjuvant Therapy for Stage III Locally Advanced Melanoma Patients

  • Katie Kinaschuk,
  • Tina Cheng,
  • Thomas Brenn,
  • J. Gregory McKinnon and
  • Claire Temple-Oberle

23 April 2023

Background: Early-phase neoadjuvant trials have demonstrated promising results in the utility of upfront immunotherapy in locally advanced stage III melanoma and unresected nodal disease. Secondary to these results and the COVID-19 pandemic, this pat...

  • Review
  • Open Access
28 Citations
11,800 Views
20 Pages

Management of Multiple Myeloma: A Review for General Practitioners in Oncology

  • Bethany E. Monteith,
  • Irwindeep Sandhu and
  • Ann S. Lee

22 April 2023

Multiple myeloma (MM) is a malignant clonal plasma cell disorder in the bone marrow and is the second-most common hematologic malignancy in adults. Although patients with MM have a moderate life expectancy, it remains a heterogeneous disease that oft...

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Curr. Oncol. - ISSN 1718-7729