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Marine Drugs, Volume 20, Issue 7

July 2022 - 60 articles

Cover Story: Marine organisms have been shown to be a valuable source for biologically active compounds for the prevention and treatment of immune system diseases as well as other pathologies. The advantage of studying marine organisms lays in their biodiversity and in the variety of chemical structures that they may produce. This review is focused on marine-derived molecules discovered in the last three years as potential immunomodulatory drugs. Studies have focused on marine organism compounds with potential pharmaceutical applications and were mainly related to the effects of molecules on macrophages and lymphocytes, also analyzing the release of immunomodulatory mediators. View this paper
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Articles (60)

  • Article
  • Open Access
6 Citations
2,636 Views
13 Pages

Analysis of Structural Determinants of Peptide MS 9a-1 Essential for Potentiating of TRPA1 Channel

  • Yulia A. Logashina,
  • Kseniya I. Lubova,
  • Ekaterina E. Maleeva,
  • Viktor A. Palikov,
  • Yulia A. Palikova,
  • Igor A. Dyachenko and
  • Yaroslav A. Andreev

21 July 2022

The TRPA1 channel is involved in a variety of physiological processes and its activation leads to pain perception and the development of inflammation. Peptide Ms 9a-1 from sea anemone Metridium senile is a positive modulator of TRPA1 and causes signi...

  • Article
  • Open Access
7 Citations
3,048 Views
8 Pages

New Glycosylated Secondary Metabolites from Marine-Derived Bacteria

  • Cao Van Anh,
  • Jong Soon Kang,
  • Hwa-Sun Lee,
  • Phan Thi Hoai Trinh,
  • Chang-Su Heo and
  • Hee Jae Shin

20 July 2022

Three new glycosylated secondary metabolites, including a new indole alkaloid, pityriacitrin D (1), and two new trehalose lipids (2 and 3), together with three known compounds (4–6) were isolated from two marine-derived bacterial strains, Bacillus si...

  • Article
  • Open Access
3 Citations
3,571 Views
22 Pages

20 July 2022

The discovery of novel secondary metabolites is actively being pursued in new ecosystems. Sponge-associated bacteria have been in the limelight in recent years on account of their ability to produce bioactive compounds. In this study, heterotrophic b...

  • Article
  • Open Access
5 Citations
3,729 Views
17 Pages

Connection of Isolated Stereoclusters by Combining 13C-RCSA, RDC, and J-Based Configurational Analyses and Structural Revision of a Tetraprenyltoluquinol Chromane Meroterpenoid from Sargassum muticum

  • Juan Carlos C. Fuentes-Monteverde,
  • Nilamoni Nath,
  • Abel M. Forero,
  • Elena M. Balboa,
  • Armando Navarro-Vázquez,
  • Christian Griesinger,
  • Carlos Jiménez and
  • Jaime Rodríguez

18 July 2022

The seaweed Sargassum muticum, collected on the southern coast of Galicia, yielded a tetraprenyltoluquinol chromane meroditerpene compound known as 1b, whose structure is revised. The relative configuration of 1b was determined by J-based configurati...

  • Article
  • Open Access
33 Citations
6,102 Views
23 Pages

First Characterization of Ostreopsis cf. ovata (Dinophyceae) and Detection of Ovatoxins during a Multispecific and Toxic Ostreopsis Bloom on French Atlantic Coast

  • Nicolas Chomérat,
  • Elvire Antajan,
  • Isabelle Auby,
  • Gwenael Bilien,
  • Liliane Carpentier,
  • Marie-Noëlle de Casamajor,
  • Florian Ganthy,
  • Fabienne Hervé,
  • Magali Labadie and
  • Claire Méteigner
  • + 5 authors

18 July 2022

Blooms of the benthic toxic dinoflagellate genus Ostreopsis have been recorded more frequently during the last two decades, particularly in warm temperate areas such as the Mediterranean Sea. The proliferation of Ostreopsis species may cause deleteri...

  • Review
  • Open Access
171 Citations
12,203 Views
13 Pages

17 July 2022

Chitin and its derivative chitosan are highly abundant polymers in nature, appearing in both the shells and exoskeletons of various marine and non-marine species. Since they possess favorable properties, such as biocompatibility, biodegradability, no...

  • Article
  • Open Access
11 Citations
3,075 Views
16 Pages

16 July 2022

Hemocyanins present in the hemolymph of invertebrates are multifunctional proteins that are responsible for oxygen transport and play crucial roles in the immune system. They have also been identified as a source of antimicrobial peptides during infe...

  • Article
  • Open Access
54 Citations
6,307 Views
18 Pages

Sulfated Polysaccharide Extracted from the Green Algae Codium bernabei: Physicochemical Characterization and Antioxidant, Anticoagulant and Antitumor Activity

  • Fabian A. Figueroa,
  • Roberto T. Abdala-Díaz,
  • Claudia Pérez,
  • Virginia Casas-Arrojo,
  • Aleksandra Nesic,
  • Cecilia Tapia,
  • Carla Durán,
  • Oscar Valdes,
  • Carolina Parra and
  • Gastón Bravo-Arrepol
  • + 3 authors

15 July 2022

Codium bernabei is a green alga that grows on Chilean coasts. The composition of its structural polysaccharides is still unknown. Hence, the aim of this work is to isolate and characterize the hot water extracted polysaccharide fractions. For this pu...

  • Article
  • Open Access
13 Citations
5,173 Views
13 Pages

Glucose Uptake and Oxidative Stress in Caco-2 Cells: Health Benefits from Posidonia oceanica (L.) Delile

  • Camilla Morresi,
  • Marzia Vasarri,
  • Luisa Bellachioma,
  • Gianna Ferretti,
  • Donatella Degl′Innocenti and
  • Tiziana Bacchetti

14 July 2022

Posidonia oceanica (L.) Delile is an endemic Mediterranean marine plant of extreme ecological importance. Previous in vitro and in vivo studies have demonstrated the potential antidiabetic properties of P. oceanica leaf extract. Intestinal glucose tr...

  • Article
  • Open Access
8 Citations
2,678 Views
12 Pages

14 July 2022

Nitzschia laevis is a candidate microorganism for bioactive compounds (fucoxanthin and eicosapentaenoic acid (EPA)) production. In this study, the impacts of glucose-induced trophic transition on biomass, photosynthesis, pigments, and lipid profiles...

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Mar. Drugs - ISSN 1660-3397Creative Common CC BY license