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Marine Drugs, Volume 20, Issue 8

August 2022 - 75 articles

Cover Story: Anthraquinones are an important group of fungal secondary metabolites which are biosynthesized via the acetate-malonate pathway. Marine-derived fungi from different ecological niches are shown to be important sources of anthraquinones and their derivatives. This class of compounds exhibits a myriad of biological and pharmacological activities such as antibacterial, antifungal, antiviral, antioxidant, anti‐inflammatory, anti‐fouling, cytotoxicity, as well as inhibition of various enzymes. This review discusses the biosynthesis, structures and sources of 296 anthraquinonoids reported in the literature from 2000 to 2021. In addition, a classification of marine-derived anthraquinones and their derivatives into subclasses, according to their scaffolds, and relevant biological/pharmacological activities of some isolated anthraquinones are highlighted. View this paper
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Articles (75)

  • Review
  • Open Access
32 Citations
8,127 Views
17 Pages

Potential Beneficial Effects of Sargassum spp. in Skin Aging

  • Min-Kyeong Lee,
  • Heeyeon Ryu,
  • Ji Yun Lee,
  • Hyeon Hak Jeong,
  • Jiwon Baek,
  • Ji Yun Van,
  • Myeong-Jin Kim,
  • Won-Kyo Jung and
  • Bonggi Lee

22 August 2022

Seaweeds are receiving much attention as a rich source of bioactive compounds with cosmeceutical potential. Recent studies have revealed that Sargassum spp., a genus of brown algae in the family Sargassaceae, has multiple functions in preventing and...

  • Review
  • Open Access
12 Citations
3,404 Views
12 Pages

An Insight into the Role of Marine Biopolymer Alginate in Endodontics: A Review

  • Galvin Sim Siang Lin,
  • Chia Yee Cher,
  • Yong Hong Goh,
  • Daryl Zhun Kit Chan,
  • Mohmed Isaqali Karobari,
  • Josephine Chang Hui Lai and
  • Tahir Yusuf Noorani

22 August 2022

Alginate is a natural marine biopolymer that has been widely used in biomedical applications, but research on its use as an endodontic material is still sparse in the literature. This pioneer review aims to summarize the emerging roles of alginate an...

  • Article
  • Open Access
9 Citations
3,156 Views
9 Pages

Halo- and Thiocarbazomycins from Coral- and Coral Reef Sands-Derived Actinomycetes

  • Qiaoling Wu,
  • Hongjie Zhu,
  • Changli Sun,
  • Le Zhou,
  • Huimin Wang,
  • Songbiao Shi,
  • Xinpeng Tian and
  • Jianhua Ju

21 August 2022

Four actinomycete strains isolated from the coral Acropora austera and coral sand samples from the South China Sea, were found to produce a series of halogenated compounds baring similar ultraviolet absorption based on the analysis of HPLC and LC-MS....

  • Article
  • Open Access
14 Citations
3,530 Views
15 Pages

Synaptamide Modulates Astroglial Activity in Mild Traumatic Brain Injury

  • Arina Ponomarenko,
  • Anna Tyrtyshnaia,
  • Darya Ivashkevich,
  • Ekaterina Ermolenko,
  • Inessa Dyuizen and
  • Igor Manzhulo

21 August 2022

At present, the study of the neurotropic activity of polyunsaturated fatty acid ethanolamides (N-acylethanolamines) is becoming increasingly important. N-docosahexaenoylethanolamine (synaptamide, DHEA) is a highly active metabolite of docosahexaenoic...

  • Review
  • Open Access
175 Citations
12,205 Views
36 Pages

Progress in Research of Chitosan Chemical Modification Technologies and Their Applications

  • Qizhou Chen,
  • Yi Qi,
  • Yuwei Jiang,
  • Weiyan Quan,
  • Hui Luo,
  • Kefeng Wu,
  • Sidong Li and
  • Qianqian Ouyang

21 August 2022

Chitosan, which is derived from chitin, is the only known natural alkaline cationic polymer. Chitosan is a biological material that can significantly improve the living standard of the country. It has excellent properties such as good biodegradabilit...

  • Article
  • Open Access
15 Citations
4,110 Views
20 Pages

Carrageenophyte Kappaphycus malesianus Inhibits Microglia-Mediated Neuroinflammation via Suppression of AKT/NF-κB and ERK Signaling Pathways

  • Nicole Jean-Yean Lai,
  • Ee-Ling Ngu,
  • Jun-Rui Pang,
  • Kah-Hui Wong,
  • Chrismawan Ardianto,
  • Long Chiau Ming,
  • Siew-Huah Lim,
  • Shweta Gangasa Walvekar,
  • Ayaz Anwar and
  • Yoon-Yen Yow

20 August 2022

Neuroinflammation is an inflammatory response in any part of the central nervous system triggered by the activation of microglia and astrocytes to produce proinflammatory cytokines in the brain. However, overproduction of proinflammatory cytokines fu...

  • Review
  • Open Access
26 Citations
5,739 Views
35 Pages

20 August 2022

Mangrove ecosystems are widely distributed in the intertidal zone of tropical and subtropical estuaries or coasts, containing abundant biological communities, for example, mangrove plants and diverse groups of microorganisms, featuring various bioact...

  • Article
  • Open Access
6 Citations
3,410 Views
20 Pages

Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082

  • Juanjuan Wang,
  • Zebin Liu,
  • Xiaowei Pan,
  • Ning Wang,
  • Legong Li,
  • Yuguang Du,
  • Jianjun Li and
  • Mei Li

20 August 2022

Fucoidans represent a type of polyanionic fucose-containing sulfated polysaccharides (FCSPs) that are cleaved by fucoidan-degrading enzymes, producing low-molecular-weight fucoidans with multiple biological activities suitable for pharmacological use...

  • Article
  • Open Access
10 Citations
4,003 Views
19 Pages

Discovery of Ircinianin Lactones B and C—Two New Cyclic Sesterterpenes from the Marine Sponge Ircinia wistarii

  • Thomas Majer,
  • Keshab Bhattarai,
  • Jan Straetener,
  • Justus Pohlmann,
  • Patrick Cahill,
  • Markus O. Zimmermann,
  • Marc P. Hübner,
  • Marcel Kaiser,
  • Johan Svenson and
  • Harald Gross
  • + 2 authors

19 August 2022

Two new ircinianin-type sesterterpenoids, ircinianin lactone B and ircinianin lactone C (7 and 8), together with five known entities from the ircinianin compound family (1, 3–6) were isolated from the marine sponge Ircinia wistarii. Ircinianin...

  • Review
  • Open Access
7 Citations
5,014 Views
20 Pages

Conotoxin Patenting Trends in Academia and Industry

  • Noemi Sanchez-Campos,
  • Johanna Bernaldez-Sarabia and
  • Alexei F. Licea-Navarro

19 August 2022

Sea snails of the genus Conus produce toxins that have been the subjects of numerous studies, projects, publications, and patents over the years. Since Conus toxins were discovered in the 1960s, their biological activity has been thought to have high...

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Mar. Drugs - ISSN 1660-3397