You are currently viewing a new version of our website. To view the old version click .

Marine Drugs, Volume 19, Issue 12

December 2021 - 65 articles

Cover Story: Chitosan is among the most studied natural origin polymers for biomedical applications. Due to its mucoadhesiveness, chitosan enables a prolonged residence time at mucosal sites; its wound-healing properties open possibilities to utilize chitosan as wound dressings with multitargeted activities and more. This review focuses on the potential of chitosan in localized antimicrobial therapy to address the challenges of current rising antimicrobial resistance. We provide an in-depth overview of state-of-the-art chitosan-based delivery systems for skin and vaginal infections, and a brief overview of chitosan’s potential in treating ocular, buccal and dental, and nasal infections. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (65)

  • Review
  • Open Access
139 Citations
11,504 Views
21 Pages

20 December 2021

Microalgae are excellent biological factories for high-value products and contain biofunctional carotenoids. Carotenoids are a group of natural pigments with high value in social production and human health. They have been widely used in food additiv...

  • Article
  • Open Access
7 Citations
3,368 Views
10 Pages

Structure Revision and Protein Tyrosine Phosphatase Inhibitory Activity of Drazepinone

  • Fei Cao,
  • Li Pan,
  • Wenbin Gao,
  • Yunfeng Liu,
  • Caijuan Zheng and
  • Yahui Zhang

20 December 2021

From the marine-derived fungus Penicillium sumatrense (Trichocomaceae), a pair of enantiomers [(+)-1 and (−)-1] were isolated with identical 1D NMR data to drazepinone, which was originally reported to have a trisubstituted naphthofuroazepinone...

  • Article
  • Open Access
12 Citations
3,569 Views
9 Pages

Mansouramycins E–G, Cytotoxic Isoquinolinequinones from Marine Streptomycetes

  • Mohamed Shaaban,
  • Khaled A. Shaaban,
  • Gerhard Kelter,
  • Heinz Herbert Fiebig and
  • Hartmut Laatsch

20 December 2021

Chemical investigation of the ethyl acetate extract from the marine-derived Streptomyces sp. isolate B1848 resulted in three new isoquinolinequinone derivatives, the mansouramycins E–G (1a–3a), in addition to the previously reported manso...

  • Article
  • Open Access
20 Citations
3,532 Views
13 Pages

18 December 2021

Oxidized low-density lipoprotein (ox-LDL)-induced oxidative injury in vascular endothelial cells is crucial for the progression of cardiovascular diseases, including atherosclerosis. Several flavonoids have been shown cardiovascular protective effect...

  • Article
  • Open Access
3 Citations
3,461 Views
14 Pages

17 December 2021

α9-containing nicotinic acetylcholine receptors (nAChRs) have been shown to play critical roles in neuropathic pain. The α-conotoxin (α-CTx) RgIA and its analog RgIA4 were identified as the most selective inhibitor of α9&alpha...

  • Review
  • Open Access
9 Citations
4,649 Views
11 Pages

Iron-Utilization System in Vibrio vulnificus M2799

  • Katsushiro Miyamoto,
  • Hiroaki Kawano,
  • Naoko Okai,
  • Takeshi Hiromoto,
  • Nao Miyano,
  • Koji Tomoo,
  • Takahiro Tsuchiya,
  • Jun Komano,
  • Tomotaka Tanabe and
  • Tatsuya Funahashi
  • + 1 author

17 December 2021

Vibrio vulnificus is a Gram-negative pathogenic bacterium that causes serious infections in humans and requires iron for growth. A clinical isolate, V. vulnificus M2799, secretes a catecholate siderophore, vulnibactin, that captures ferric ions from...

  • Article
  • Open Access
6 Citations
3,513 Views
10 Pages

Volatile Organic Compounds, Indole, and Biogenic Amines Assessment in Two Mediterranean Irciniidae (Porifera, Demospongiae)

  • Antonella Aresta,
  • Pietro Cotugno,
  • Nicoletta De Vietro,
  • Caterina Longo,
  • Maria Mercurio,
  • Pere Ferriol,
  • Carlo Zambonin and
  • Carlotta Nonnis Marzano

17 December 2021

Solid phase microextraction (SPME) coupled to gas chromatography-mass spectrometry (GC-MS) was employed for the headspace determination of the volatile organic fraction emitted by two of the most common Mediterranean demosponges, Ircinia variabilis a...

  • Article
  • Open Access
9 Citations
4,635 Views
17 Pages

A Novel Pseudoalteromonas xiamenensis Marine Isolate as a Potential Probiotic: Anti-Inflammatory and Innate Immune Modulatory Effects against Thermal and Pathogenic Stresses

  • Withanage Prasadini Wasana,
  • Amal Senevirathne,
  • Chamilani Nikapitiya,
  • Tae-Yang Eom,
  • Youngdeuk Lee,
  • Jong-Soo Lee,
  • Do-Hyung Kang,
  • Chulhong Oh and
  • Mahanama De Zoysa

15 December 2021

A marine bacterial strain was isolated from seawater and characterized for it beneficial probiotic effects using zebrafish as a model system. The strain was identified by morphological, physiological, biochemical, and phylogenetic analyses. The strai...

  • Review
  • Open Access
104 Citations
11,382 Views
34 Pages

15 December 2021

Alginate is a natural polysaccharide that typically originates from various species of algae. Due to its low cost, good biocompatibility, and rapid ionic gelation, the alginate hydrogel has become a good option of bioink source for 3D bioprinting. Ho...

  • Article
  • Open Access
4 Citations
2,918 Views
13 Pages

The 3/4- and 3/6-Subfamily Variants of α-Conotoxins GI and MI Exhibit Potent Inhibitory Activity against Muscular Nicotinic Acetylcholine Receptors

  • Xiaoli Ma,
  • Qiuyuan Huang,
  • Shuo Yu,
  • Shujing Xu,
  • Yue Huang,
  • Zhiming Zhao,
  • Xinrong Xiao and
  • Qiuyun Dai

14 December 2021

α-Conotoxins GI and MI belong to the 3/5 subfamily of α-conotoxins and potently inhibit muscular nicotinic acetylcholine receptors (nAChRs). To date, no 3/4- or 3/6-subfamily α-conotoxins have been reported to inhibit muscular nAChRs. In the present...

of 7

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Mar. Drugs - ISSN 1660-3397