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Medicina, Volume 61, Issue 7

July 2025 - 198 articles

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Cover Story: This image captures a digital subtraction angiography (DSA) of the ophthalmic artery prior to intra-arterial chemotherapy in a patient with retinoblastoma. The dense, tangled vasculature within the globe highlights the tumor’s robust blood supply and the precision required for targeted chemotherapeutic delivery. Intra-arterial chemotherapy has transformed retinoblastoma management by maximizing local efficacy and minimizing systemic toxicity. This vascular roadmap underscores the sophistication of modern ocular oncology and the importance of image-guided therapy in preserving life and vision. View this paper

Articles (198)

  • Article
  • Open Access
852 Views
21 Pages

Development and Validation of Predictive Models for Non-Adherence to Antihypertensive Medication

  • Cristian Daniel Marineci,
  • Andrei Valeanu,
  • Cornel Chiriță,
  • Simona Negreș,
  • Claudiu Stoicescu and
  • Valentin Chioncel

21 July 2025

Background and Objectives: Investigating the adherence to antihypertensive medication and identifying patients with low adherence allows targeted interventions to improve therapeutic outcomes. Artificial intelligence (AI) offers advanced tools for an...

  • Review
  • Open Access
1,256 Views
46 Pages

Visceral Arterial Pseudoaneurysms—A Clinical Review

  • Ashita Ashish Sule,
  • Shreya Sah,
  • Justin Kwan,
  • Sundeep Punamiya and
  • Vishal G. Shelat

21 July 2025

Background and Objectives: Visceral arterial pseudoaneurysms (VAPAs) are rare vascular lesions characterized by the disruption of partial disruption of the arterial wall, most commonly involving the intima and media. They have an estimated incidence...

  • Article
  • Open Access
1 Citations
617 Views
28 Pages

21 July 2025

Background and Objectives: Congenital heart defects (CHD) affect around 1% of the population, making them the most common congenital disease worldwide. Thanks to advances in treatment, over 90% of affected children are able to reach adulthood, shifti...

  • Systematic Review
  • Open Access
800 Views
21 Pages

Challenges in Identifying Biomarkers of Frailty Syndrome: A Systematic Review

  • Indira Omarova,
  • Ainur Yeshmanova,
  • Gulzhan Gabdulina,
  • Aigul Tazhiyeva,
  • Shynar Ryspekova,
  • Akmaral Abdykulova,
  • Ainur Nuftieva,
  • Tamara Abdirova,
  • Dame Sailanova and
  • Zhanar Mombiyeva
  • + 1 author

21 July 2025

Background and Objectives: The aim of this study is to categorize and combine (according to the source of biomaterial) biomarkers of frailty syndrome and identify challenges in research on these biomarkers by reviewing the current literature from the...

  • Review
  • Open Access
714 Views
14 Pages

Integrating Radiomics and Deep-Learning for Prognostic Evaluation in Nasopharyngeal Carcinoma

  • Irina Maria Pușcaș,
  • Anda Gâta,
  • Alexandra Roman,
  • Silviu Albu,
  • Vlad Alexandru Gâta and
  • Alexandru Irimie

21 July 2025

Nasopharyngeal carcinoma (NPC) represents a prevalent malignant tumor within the head and neck region, and enhancing the precision of prognostic assessments is a critical objective. Recent advancements in the integration of artificial intelligence (A...

  • Systematic Review
  • Open Access
1,076 Views
12 Pages

21 July 2025

Background and Objectives: Acute appendicitis is a common cause of abdominal pain requiring surgery in pediatric patients. Given concerns regarding radiation exposure from computed tomography (CT), ultrasound (US) has become the first-line diagnostic...

  • Review
  • Open Access
1 Citations
744 Views
20 Pages

Sarcopenia in Urothelial Bladder Carcinoma: A Narrative Review

  • Constantin Radu Vrabie,
  • Andreea Ioana Parosanu and
  • Cornelia Nitipir

20 July 2025

Background and Objectives: Urothelial bladder carcinoma includes a spectrum of malignant lesions with heterogeneous molecular, biological, and clinical features and a variable risk of progression from non-muscle-invasive bladder cancer (NMIBC) to mus...

  • Article
  • Open Access
525 Views
16 Pages

The Impact of Synbiotics on the Bacterial Flora During the Course of Chronic Sinusitis

  • Karolina Goroszkiewicz,
  • Grażyna Lisowska,
  • Grażyna Stryjewska-Makuch,
  • Olga Karłowska-Bijak and
  • Maciej Misiołek

20 July 2025

Background and objectives: Chronic rhinosinusitis (CRS) is a multifactorial inflammatory condition often associated with microbiome imbalance (dysbiosis). Recent studies highlight the potential role of synbiotics—combinations of probiotics and...

  • Article
  • Open Access
589 Views
11 Pages

20 July 2025

Background and Objectives: Adequate bone quality is essential for promoting initial bone ingrowth and preventing early migration during cementless total knee arthroplasty (TKA). However, gold-standard criteria for identifying suitable bone strength h...

  • Article
  • Open Access
590 Views
14 Pages

Ultrasound-Based Morphological and Functional Assessment in Male CrossFit Athletes with Unilateral Subacromial Shoulder Pain: An Observational Study

  • Fabien Guerineau,
  • Ann Cools,
  • Jaime Almazán-Polo,
  • María Dolores Sosa-Reina,
  • Vanesa Abuín-Porras,
  • Cristian Baroa-Fernández,
  • Pablo García-Ginés,
  • Ana Román-Franganillo and
  • Ángel González-de-la-Flor

19 July 2025

Background and Objectives: CrossFit is a discipline involving a wide range of overhead movements performed at high intensity and under accumulated fatigue that predispose to a high risk of shoulder complex injuries. This study aimed to compare ultras...

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Medicina - ISSN 1648-9144Creative Common CC BY license