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Medicina, Volume 61, Issue 8

2025 August - 189 articles

Cover Story: Alzheimer’s disease research is rapidly shifting from late-stage diagnosis to early detection and precision therapies. This figure illustrates the evolving Alzheimer’s disease landscape, emphasizing the shift from diagnosis to treatment. Early biomarkers, including tau hyperphosphorylation, genetic mutations (APP, ApoE, and PSEN1), and β-amyloid aggregation, enable earlier detection. Neuroimaging tools such as PET and MRI improve diagnostic accuracy. On the therapeutic side, disease-modifying agents like monoclonal antibodies (Lecanemab, Aducanumab), nanoparticles, and focused ultrasounds are highlighted as emerging interventions. Together, these advances can enable the earlier diagnosis and more effective treatment of Alzheimer’s disease. View this paper
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Articles (189)

  • Review
  • Open Access
2,636 Views
12 Pages

Effectiveness of Non-Pharmacological Interventions in Patients with Facial Paralysis: An Umbrella and Mapping Review

  • Mónica Grande-Alonso,
  • Alba Ayllón-Poza,
  • Álvaro Saavedra-Böss,
  • Nayra Daniela Santa Cruz-Saavedra,
  • Celia Vidal-Quevedo,
  • Carlos Forner-Álvarez and
  • Ferran Cuenca-Martínez

21 August 2025

Background and Objectives: Facial paralysis involves the complete or partial loss of facial movement due to damage to the facial nerve, leading to impaired voluntary muscle function and facial asymmetry. Given its significant physical and psychosocia...

  • Article
  • Open Access
759 Views
14 Pages

Decoding the Spitz Puzzle: Histological Patterns and Diagnostic Challenges in Everyday Pathology Practice—A Single-Center Study

  • Iuliu Gabriel Cocuz,
  • Georgian-Nicolae Radu,
  • Maria Cătălina Popelea,
  • Raluca Niculescu,
  • Maria Elena Cocuz,
  • Adrian-Horațiu Sabău,
  • Andreea-Cătălina Tinca,
  • Andreea Raluca Cozac-Szoke,
  • Bogdan Pastor and
  • Ovidiu Simion Cotoi
  • + 3 authors

21 August 2025

Background and Objectives: Spitz tumors represent a diagnostic challenge in dermatopathology due to their large spectrum of morphological characteristics and overlap with malignant lesions, especially in pathology departments where molecular patholog...

  • Review
  • Open Access
1,551 Views
15 Pages

A Critical Narrative Review of Coaxial Double-Pigtail Stenting Within the LAMS in the Management of Pancreatic Fluid Collections

  • Giuseppe Infantino,
  • Gabriele Rancatore,
  • Dario Quintini,
  • Lucio Carrozza,
  • Dario Ligresti,
  • Marco Giacchetto,
  • Nicoletta Belluardo,
  • Giuseppe Rizzo,
  • Elio D’Amore and
  • Ilaria Tarantino
  • + 1 author

21 August 2025

Endoscopic ultrasound (EUS)-guided drainage using lumen-apposing metal stents (LAMSs) has become the standard for managing pancreatic fluid collections (PFCs), especially walled-off necrosis (WON). However, LAMS-specific adverse events (AEs), includi...

  • Review
  • Open Access
4 Citations
4,180 Views
23 Pages

Human Papillomavirus Across the Reproductive Lifespan: An Integrative Review of Fertility, Pregnancy Outcomes, and Fertility-Sparing Management

  • Matteo Terrinoni,
  • Tullio Golia D’Augè,
  • Giuseppe Mascellino,
  • Federica Adinolfi,
  • Michele Palisciano,
  • Dario Rossetti,
  • Gian Carlo Di Renzo and
  • Andrea Giannini

21 August 2025

Background and Objectives: Human papillomavirus (HPV) is the most prevalent sexually transmitted infection worldwide and, beyond its oncogenic potential, may impair reproductive health in both sexes. This review examines HPV’s effects on male a...

  • Article
  • Open Access
867 Views
16 Pages

21 August 2025

Background and Objectives: Metabolic syndrome (MetS) progresses gradually as individual components accumulate. However, there is limited understanding regarding whether the sequence of component appearance influences disease progression. This study s...

  • Systematic Review
  • Open Access
2 Citations
1,679 Views
23 Pages

21 August 2025

Background and Objectives: Medication-related osteonecrosis of the jaw (MRONJ) is a challenging condition linked to antiresorptive and antiangiogenic medications. Their complex pathophysiology and resistance to standard treatments have led researcher...

  • Review
  • Open Access
1,447 Views
15 Pages

Artificial Intelligence in the Diagnosis and Imaging-Based Assessment of Pelvic Organ Prolapse: A Scoping Review

  • Marian Botoncea,
  • Călin Molnar,
  • Vlad Olimpiu Butiurca,
  • Cosmin Lucian Nicolescu and
  • Claudiu Molnar-Varlam

21 August 2025

Background and Objectives: Pelvic organ prolapse (POP) is a complex condition affecting the pelvic floor, often requiring imaging for accurate diagnosis and treatment planning. Artificial intelligence (AI), particularly deep learning (DL), is emergin...

  • Article
  • Open Access
1,080 Views
11 Pages

Inflammatory Biomarkers and Carotid Atherosclerosis: The Predictive Role of the Neutrophil/Albumin Ratio

  • Halis Yilmaz,
  • Cemre Turgul,
  • Yucel Yilmaz,
  • Saban Kelesoglu and
  • Aydin Tuncay

21 August 2025

Background and Objectives: Carotid artery stenosis is an inflammatory vascular disease closely linked to atherosclerosis and associated with inflammatory biomarkers. The neutrophil/albumin ratio (NAR) is a novel promising biomarker in assessing cardi...

  • Article
  • Open Access
1,645 Views
12 Pages

21 August 2025

Background and Objectives: Adolescent diaphyseal clavicle fracture surgery has increased in recent years. However, the optimal operative method remains debated, particularly between elastic stable intramedullary nailing (ESIN) and plate fixation. Thi...

  • Article
  • Open Access
1,234 Views
13 Pages

Selective Advantage of NACT in Advanced Ovarian Cancer: A Retrospective Single-Centre Analysis

  • Adrienne Szilvia Berczi,
  • Olivér Lampé,
  • Zoárd Tibor Krasznai,
  • Mónika Orosz,
  • Lili Fábián and
  • Rudolf Lampé

20 August 2025

Background and Objectives: Advanced-stage epithelial ovarian cancer (EOC) is associated with poor prognosis, with complete macroscopic cytoreduction representing the strongest modifiable predictor of survival. Neoadjuvant chemotherapy (NACT) followed...

  • Article
  • Open Access
1,105 Views
11 Pages

Reliability of Body Fat Percentage Measurements and Their Impact on Airway Resistance: Does Leptin Play a Significant Role?

  • Rodrigo Muñoz-Cofré,
  • Edgardo Rojas-Mancilla,
  • Pablo A. Lizana,
  • Máximo Escobar-Cabello,
  • Claudio García-Herrera,
  • Daniel Conei,
  • Fernando Valenzuela-Aedo,
  • Francisco Javier Soto-Rodríguez and
  • Mariano del Sol

20 August 2025

Background/Objectives: The measurement of body fat percentage (%BF) could alert us to potential respiratory problems; however, differences in %BF values have been reported depending on the method used. Therefore, the objectives of this study were to...

  • Article
  • Open Access
1,600 Views
15 Pages

20 August 2025

Background and Objectives: This retrospective single-center study aimed to evaluate the epidemiological, clinical, and laboratory characteristics of syphilis cases diagnosed at our hospital between 2005 and 2024, with a focus on the performance of se...

  • Article
  • Open Access
1,230 Views
17 Pages

The Use of Serum Scoring Systems in Predicting Liver Fibrosis Caused by Chronic Hepatitis B: A Retrospective Case-Control Study

  • Müge Özgüler,
  • Samet Durak,
  • Özgen Arslan Solmaz,
  • Gülden Eser Karlıdağ,
  • Ömür Gündağ,
  • Yasemin Kırık,
  • Büşra Tanır and
  • Sümeyye Selim Kara

20 August 2025

Background and Objectives: Early diagnosis and monitoring of liver fibrosis in chronic hepatitis B are crucial for effective disease management and prognosis. Traditionally, percutaneous liver biopsy has been regarded as the gold standard for assessi...

  • Review
  • Open Access
1,692 Views
16 Pages

Psychoneurobiological Aspects of Burning Mouth Syndrome and Oral Lichen Planus: A Narrative Review

  • Dora Martić,
  • Ana Glavina,
  • Liborija Lugović-Mihić and
  • Maja Vilibić

20 August 2025

Burning mouth syndrome (BMS) and oral lichen planus (OLP) are two chronic oral diseases/disorders that continue to pose a challenge for conventional diagnosis and treatment. Both diseases do not occur in isolation but rather appear to reflect a broad...

  • Systematic Review
  • Open Access
2,104 Views
24 Pages

The Effects of Hyaluronic Acid on Gait Parameters in Patients with Knee Osteoarthritis: A Systematic Literature Review

  • Cosimo Costantino,
  • Sara Ronzoni,
  • Annalisa Ingletto,
  • Roberto Sabato,
  • Antonello Salerno,
  • Stefano Palermi,
  • Ruben Foresti,
  • Chiara Martini and
  • Andrea Demeco

20 August 2025

Background and Objectives: Knee Osteoarthritis affects about 10% of people over 50, causing pain and functional limitation. Hyaluronic acid (HA) is crucial in regulating the osteocartilaginous matrix. Patients are usually assessed using clinical scor...

  • Article
  • Open Access
3 Citations
1,621 Views
15 Pages

A Single Bout of Foam Rolling After Nordic Hamstring Exercise Improves Flexibility but Has No Effect on Muscle Stiffness or Functional Muscle Parameters

  • Coşkun Rodoplu,
  • Christian Burger,
  • Josef Fischer,
  • Josefina Manieu Seguel,
  • Ramiz Arabacı and
  • Andreas Konrad

19 August 2025

Background and Objectives: The Nordic hamstring exercise (NHE) effectively strengthens the hamstrings, reduces the risk of hamstring strain, and induces fatigue in the muscles; thus, post-NHE recovery strategies should be optimized. Foam rolling (FR)...

  • Article
  • Open Access
1 Citations
1,193 Views
13 Pages

Optimal Maintenance Strategy for Patients with Improved Left Ventricular Function Following Sacubitril/Valsartan Therapy

  • Yoonjee Park,
  • Minjung Bak,
  • Heayoung Shin,
  • David Hong,
  • Jeong Hoon Yang,
  • Darae Kim,
  • Eun-Seok Jeon and
  • Jin-Oh Choi

19 August 2025

Background and Objectives: Optimal pharmacological treatment following left ventricular ejection fraction (LVEF) improvement remains largely unknown. This study compared the clinical outcomes of patients with heart failure (HF) with improved EF (HFim...

  • Article
  • Open Access
1,030 Views
9 Pages

19 August 2025

Background and Objectives: As maternal mortality has become increasingly rare in developed countries, it is no longer a reliable metric for evaluating obstetric care quality. To address this limitation, the World Health Organization (WHO) introduced...

  • Article
  • Open Access
1,297 Views
12 Pages

Low-Density Lipoprotein Cholesterol Target Attainment in Lithuania: A Nationwide Analysis of Real-World Health Data

  • Gediminas Urbonas,
  • Tomas Lapinskas,
  • Indrė Čeponienė,
  • Olga Vasiliauskienė,
  • Jelena Umbrasienė,
  • Ingrida Grabauskytė and
  • Jurgita Plisienė

19 August 2025

Background and Objectives: Low-density lipoprotein cholesterol (LDL-C) reduction is critical for cardiovascular disease (CVD) prevention. This study aimed to assess the proportion of patients achieving the LDL-C target in Lithuania and to identify fa...

  • Review
  • Open Access
1 Citations
2,587 Views
16 Pages

Desquamative Gingivitis Revisited: A Narrative Review on Pathophysiology, Diagnostic Challenges, and Treatment

  • Doina Iulia Rotaru,
  • Ioana Chifor Porumb,
  • Lorentz Jäntschi and
  • Radu Marcel Chisnoiu

19 August 2025

Background and objectives: Desquamative gingivitis (DG) is a clinical term used to describe gingival conditions marked by erythema (unrelated to dental plaque), epithelial desquamation, and various intraoral lesions, with occasional extraoral involve...

  • Article
  • Open Access
965 Views
13 Pages

Toward Standardized Assessment of Dynamic Subjective Visual Vertical: Effects of Visual Stimulus Intensity in Health and Multiple Sclerosis

  • Tautvydas Klėgėris,
  • Diego Kaski,
  • Renata Balnytė,
  • Virgilijus Uloza,
  • Alina Kuzminienė and
  • Ingrida Ulozienė

18 August 2025

Background and Objectives: Decreased balance function in multiple sclerosis (MS) patients is influenced by impaired gravity perception, which can be measured by the subjective visual vertical (SVV) test. The value of this test can be increased by exe...

  • Article
  • Open Access
999 Views
9 Pages

18 August 2025

Background and Objectives: Transpyloric (TP) feeding tube placement is a viable nutritional strategy in low birth weight infants (LBWIs) with severe gastroesophageal reflux or feeding intolerance. However, technical challenges are encountered in pati...

  • Article
  • Open Access
1 Citations
951 Views
13 Pages

Association of Apolipoprotein C-III Gene Polymorphisms (rs2854116 and rs2854117) with Susceptibility to Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in a Turkish Population

  • Damla Karaagac,
  • Suat Morkuzu,
  • Naci Senkal,
  • Ersel Bilgin,
  • Yasemin Oyacı,
  • Tufan Tükek,
  • Sacide Pehlivan and
  • Alpay Medetalibeyoglu

18 August 2025

Background and Objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by the accumulation of fat in the liver, progressing from simple steatosis to various complications, with increasing prevalence in the modern...

  • Article
  • Open Access
4 Citations
3,697 Views
14 Pages

Epidemiology of Tennis-Related Injuries Among Competitive Youth Players in Tunisia: Frequency, Characteristics, and Management Patterns

  • Saoussen Layouni,
  • Ismail Dergaa,
  • Hela Ghali,
  • Halil İbrahim Ceylan,
  • Valentina Stefanica,
  • Marwa Neguez,
  • Ines Loubiri,
  • Wissem Dhahbi,
  • Chaima Rjiba and
  • Helmi Ben Saad
  • + 3 authors

18 August 2025

Background and Objectives: Tennis involves repetitive high-velocity movements, rapid directional changes, and challenging environmental conditions, exposing players to injury risk. However, injury surveillance data for North African youth players are...

  • Article
  • Open Access
1,265 Views
11 Pages

Free vs. Local Tissue Transfer and Reconstruction in Pediatric Head and Neck Cancer Patients: A Comparable Complication Outcome Review

  • Valeria Mejia,
  • Asli Pekcan,
  • Melanie Bakovic,
  • Raina Kushal Patel,
  • Marvee Turk,
  • Idean Roohani,
  • Pasha Shakoori,
  • Mark Urata and
  • Jeffrey A. Hammoudeh

18 August 2025

Background and Objectives: Reconstructive outcomes following head and neck (H&N) cancer resection in pediatric patients remain understudied, particularly regarding the comparative efficacy of free versus local tissue transfer. Materials and Metho...

  • Systematic Review
  • Open Access
1 Citations
4,800 Views
21 Pages

Interventional Procedures in Deep Venous Thrombosis Treatment: A Review of Techniques, Outcomes, and Patient Selection

  • Arkadiusz Kacała,
  • Mateusz Dorochowicz,
  • Jędrzej Fischer,
  • Adrian Korbecki,
  • Aleksander Truszyński,
  • Anna Madura,
  • Krzysztof Dyś,
  • Andrzej Szuba and
  • Maciej Guziński

18 August 2025

Background and Objectives: Deep venous thrombosis (DVT) is associated with pulmonary embolism and long-term complications such as post-thrombotic syndrome (PTS). Anticoagulation prevents thrombus extension but does not actively remove clot. Intervent...

  • Article
  • Open Access
1,033 Views
9 Pages

Health-Related QoL of Hypertensive Patients in Bulgaria—Population-Based, Regional Pilot Study

  • Zornitsa Mitkova,
  • Elena Dimitrova,
  • Hristiana Tomova,
  • Nikolay Gerasimov,
  • Diyan Gospodinov,
  • Konstantin Mitov,
  • Stamen Pishev,
  • Boryana Parashkevova and
  • Guenka Petrova

17 August 2025

Background and Objectives: The goal of this study is to assess health-related quality of life (HRQoL) using the EuroQoL (EQ-5D-5L) and identify factors that might contribute to it. Materials and Methods: This is a real-life, observational study invol...

  • Article
  • Open Access
1 Citations
1,487 Views
13 Pages

16 August 2025

Background and Objectives: Diabetes is a known risk factor for postoperative delirium (POD); however, the relationship between the markers of glycemic control and the occurrence of POD in noncardiac surgery is not established. We initiated this pilot...

  • Article
  • Open Access
1,141 Views
18 Pages

16 August 2025

Background and Objectives: This study aimed to assess the association between relative grip strength (RGS) and metabolic syndrome (MetS) in Korean adults and to explore sex- and age-specific cutoff values for screening purposes. Materials and Methods...

  • Review
  • Open Access
1,433 Views
11 Pages

Heart Failure in Poland: A 20-Year Epidemiological Perspective

  • Michał Bohdan,
  • Anna Kowalczys,
  • Jadwiga Nessler,
  • Ewa Straburzyńska-Migaj,
  • Marcin Gruchała and
  • Małgorzata Lelonek

16 August 2025

Background and Objectives: Cardiovascular diseases (CVDs) remain the leading cause of mortality in Poland, with heart failure (HF) presenting a significant public health issue. Materials and Methods: This study aimed to analyze trends in HF incidence...

  • Article
  • Open Access
2,140 Views
9 Pages

Efficacy of Dupilumab in Patients with Chronic Rhinosinusitis with Nasal Polyps and Eosinophilic Otitis Media: A Six-Month Observational Study

  • Cosimo Galletti,
  • Federica Giammona Indaco,
  • Daniele Portelli,
  • Giulia Laterra,
  • Patrizia Zambito,
  • Maria Grazia Ferrisi,
  • Leonard Freni,
  • Francesco Ciodaro,
  • Francesco Freni and
  • Bruno Galletti
  • + 1 author

15 August 2025

Background and Objectives: Chronic rhinosinusitis with nasal polyps (CRSwNP) and eosinophilic otitis media (EOM) are frequently co-existing eosinophilic disorders related to type 2 inflammation, which significantly impair the quality of life of patie...

  • Review
  • Open Access
5 Citations
3,581 Views
19 Pages

Coronary Angioplasty with Drug-Coated Balloons: Pharmacological Foundations, Clinical Efficacy, and Future Directions

  • Valentin Chioncel,
  • Flavius Gherasie,
  • Alexandru Iancu and
  • Anamaria-Georgiana Avram

15 August 2025

Drug-coated balloons (DCBs) have transformed percutaneous coronary intervention (PCI) by delivering antiproliferative drugs directly to the arterial wall, offering a stent-less approach that mitigates the risks associated with permanent metallic impl...

  • Article
  • Open Access
1 Citations
1,007 Views
21 Pages

Right Ventricular Function Improves After Bench Press: A Speckle Tracking Echocardiography Study

  • María Belén Martínez-Lechuga,
  • Javier Hidalgo-Martín and
  • Manuel Ruiz-Bailén

15 August 2025

Objective: The association between right ventricular myocardial fiber deformation and nutrition in weightlifters has not been fully characterized. This study analyzed nutritional factors and right ventricle speckle tracking echocardiography parameter...

  • Article
  • Open Access
3 Citations
1,395 Views
16 Pages

Cardiovascular Risk in People Living with HIV: A Preliminary Case Study from Romania

  • Manuela Arbune,
  • Alina Plesea-Condratovici,
  • Anca-Adriana Arbune,
  • Geanina Andronache,
  • Catalin Plesea-Condratovici and
  • Cristian Gutu

15 August 2025

Background and Objectives: AIDS-related mortality has significantly decreased due to antiretroviral therapy (ART), leading to a substantial increase in average lifespan. Consequently, cardiovascular diseases have become a growing concern among people...

  • Article
  • Open Access
2,457 Views
16 Pages

Evaluation of PD-L1 Expression and Anti-EGFR Therapy in EGFR-Mutant Non-Small-Cell Lung Cancer

  • Gizem Teoman,
  • Elanur Karaman,
  • Şafak Ersöz and
  • Sevdegül Aydın Mungan

15 August 2025

Background and Objectives: Non-small-cell lung cancer (NSCLC) often has epidermal growth factor receptor (EGFR) mutations, which are key targets for therapy. EGFR mutation subtypes, especially exon 19 deletions and exon 21 L858R mutations, influence...

  • Article
  • Open Access
1,015 Views
17 Pages

Prognostic Significance of aVR Lead and QTc Prolongation in Patients with Early Repolarization

  • Ertugrul Altinbilek,
  • Abuzer Coskun,
  • Burak Demirci,
  • Ismail Oymak,
  • Mustafa Calik,
  • Derya Öztürk,
  • Mustafa Ahmet Afacan and
  • Burcu Bayramoglu

14 August 2025

Background and Objectives: Early repolarization (ER), previously considered benign for many years, is now recognized as a substantial risk factor for malignant arrhythmia, coronary artery disease, and mortality. The ER pattern, previously regarded as...

  • Review
  • Open Access
1 Citations
4,058 Views
44 Pages

From Better Diagnostics to Earlier Treatment: The Rapidly Evolving Alzheimer’s Disease Landscape

  • Anastasia Bougea,
  • Manuel Debasa-Mouce,
  • Shelly Gulkarov,
  • Mónica Castro-Mosquera,
  • Allison B. Reiss and
  • Alberto Ouro

14 August 2025

Background and Objectives: Over the past few years, there has been a significant shift in focus from developing better diagnostic tools to detecting Alzheimer’s disease (AD) earlier and initiating treatment interventions. This review will explo...

  • Article
  • Open Access
2 Citations
2,670 Views
22 Pages

The Association Between Borderline Personality Disorder Symptoms and Social Behaviour Among University Students

  • Andreea Sălcudean,
  • Iustin Olariu,
  • Mădălina-Gabriela Cincu,
  • Ramona Amina Popovici,
  • Iuliana Comșulea,
  • Cristina-Raluca Bodo,
  • Dora-Mihaela Cîmpian and
  • Elena-Gabriela Strete

14 August 2025

Background and Objectives: Borderline personality disorder (BPD) is a complex psychiatric condition characterized by emotional instability, impulsivity, a fluctuating self-image, and persistent difficulties in maintaining close interpersonal relation...

  • Article
  • Open Access
1,096 Views
11 Pages

14 August 2025

Background and Objectives: The effect of AR expression on prognosis in hormone receptor-positive her2-negative breast cancer is controversial. There are studies showing that AR is a treatment target, a mechanism of resistance to endocrine treatments,...

  • Systematic Review
  • Open Access
1,794 Views
22 Pages

Total Intravenous Versus Inhalational Anesthesia in High-Grade Glioma Surgery: A Systematic Review and Meta-Analysis

  • Plamen Penchev,
  • Boris Tablov,
  • Mariano Gallo Ruelas,
  • Daniela Milanova-Ilieva,
  • Lyubomir Gaydarski,
  • Nikolay Yordanov,
  • Eduardo Alonso,
  • Danna Espinoza,
  • Petar-Preslav Petrov and
  • Nikolai Ramadanov
  • + 4 authors

14 August 2025

Background and Objectives: High-grade gliomas (HGGs) are aggressive primary brain tumors with a poor prognosis despite multimodal treatment. The anesthetic technique used during surgery may influence tumor progression and survival, but its role in HG...

  • Article
  • Open Access
1,732 Views
15 Pages

Dual-Compartment Anti-Inflammatory and Chondroprotective Effects of Intra-Articular Hydrolyzed Collagen in Experimental Osteoarthritis

  • Mustafa Dinç,
  • Ömer Cevdet Soydemir,
  • Recep Karasu,
  • Aysun Saricetin and
  • Hunkar Cagdas Bayrak

14 August 2025

Background and Objectives: Osteoarthritis (OA) is a degenerative joint disease involving inflammation, oxidative stress, and extracellular matrix (ECM) degradation, leading to cartilage damage and joint dysfunction. This study aimed to evaluate the c...

  • Review
  • Open Access
1,441 Views
11 Pages

Applications of Deep Learning Models in Laparoscopy for Gynecology

  • Fani Gkrozou,
  • Vasileios Bais,
  • Charikleia Skentou,
  • Dimitrios Rafail Kalaitzopoulos,
  • Georgios Grigoriadis,
  • Anastasia Vatopoulou,
  • Minas Paschopoulos and
  • Angelos Daniilidis

14 August 2025

Background and Objectives: The use of Artificial Intelligence (AI) in the medical field is rapidly expanding. This review aims to explore and summarize all published research on the development and validation of deep learning (DL) models in gynecolog...

  • Review
  • Open Access
1,872 Views
15 Pages

Peripheral Parenteral Nutrition and Personalized Nutritional Approach After Colorectal Resection Surgery: A Comprehensive Review of Current Evidence

  • Maximos Frountzas,
  • Dimitrios Stefanoudakis,
  • Evgenia Mela,
  • Panagiotis Theodorou,
  • George E. Theodoropoulos,
  • Dimitrios Theodorou and
  • Konstantinos G. Toutouzas

14 August 2025

Major surgical operations of the gastrointestinal tract, such as colorectal resections, lead to significant burden on the human body, which is expressed during the first postoperative hours with an intense inflammatory reaction and consumption of a l...

  • Article
  • Open Access
2 Citations
1,077 Views
9 Pages

14 August 2025

Background and Objectives: Hemoglobinopathies are genetic disorders of hemoglobin and are among the most common inherited diseases. The prevalence rates of sickle cell disease and thalassemia in Saudi Arabia are higher than those in other countries i...

  • Article
  • Open Access
1,404 Views
13 Pages

Challenges in Diagnosing Pediatric Monteggia Fractures: Role of Clinical Experience and Imaging

  • Min Hyeok Choi,
  • Min Hui Moon,
  • Suk Woong Kang,
  • Kyeong Baek Kim,
  • Tae Young Ahn and
  • Jung Yun Bae

13 August 2025

Background and Objectives: Monteggia fracture-dislocations are rare but critical injuries in children. Accurate early diagnosis is essential to avoid long-term complications; however, such injuries are frequently missed. Therefore, this study aimed t...

  • Article
  • Open Access
2 Citations
1,811 Views
23 Pages

13 August 2025

Background and Objectives: Feces-induced peritonitis (FIP), a clinically relevant model of polymicrobial sepsis, induces systemic inflammation and acute lung injury (ALI). Methylene blue (MB), a phenothiazine-based compound, exhibits vasoregulatory,...

  • Article
  • Open Access
2 Citations
956 Views
12 Pages

Predictive Value of the Cally Score in Determining Surgical Strategy for Complicated Left-Sided Colonic Diverticulitis: A Retrospective Cohort Study

  • Feyyaz Gungor,
  • Huseyin Kılavuz,
  • Muhammed Furkan Arslan,
  • Murat Demir,
  • Yusuf Yunus Korkmaz,
  • Ali Bekraki and
  • Idris Kurtulus

13 August 2025

Background and Objectives: Complicated left-sided colonic diverticulitis is one of the important causes of hospital admissions and emergency surgery in industrialized societies and requires serious clinical decision-making processes for patient manag...

  • Article
  • Open Access
741 Views
13 Pages

Reduced Motor Individuality in Older Adults Revealed by Network-Based Gait Fingerprinting

  • Emahnuel Troisi Lopez,
  • Roberta Minino,
  • Mariam Maisuradze,
  • Francesca Latino and
  • Maria Giovanna Tafuri

12 August 2025

Background and Objectives: Gait is a fundamental human behavior essential for individual autonomy and well-being; it reflects a complex inter-joint coordination that can change with aging. Materials and Methods: This study applied a network-based fin...

  • Review
  • Open Access
3 Citations
3,809 Views
35 Pages

Advanced MRI, Radiomics and Radiogenomics in Unravelling Incidental Glioma Grading and Genetic Status: Where Are We?

  • Alessia Guarnera,
  • Tamara Ius,
  • Andrea Romano,
  • Daniele Bagatto,
  • Luca Denaro,
  • Denis Aiudi,
  • Maurizio Iacoangeli,
  • Mauro Palmieri,
  • Alessandro Frati and
  • Alessandro Bozzao
  • + 1 author

12 August 2025

The 2021 WHO classification of brain tumours revolutionised the oncological field by emphasising the role of molecular, genetic and pathogenetic advances in classifying brain tumours. In this context, incidental gliomas have been increasingly identif...

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Medicina - ISSN 1648-9144