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Pharmaceuticals, Volume 7, Issue 8

2014 August - 4 articles

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Articles (4)

  • Article
  • Open Access
9 Citations
6,959 Views
19 Pages

Mitochondrial Targeted Endonuclease III DNA Repair Enzyme Protects against Ventilator Induced Lung Injury in Mice

  • Masahiro Hashizume,
  • Marc Mouner,
  • Joshua M. Chouteau,
  • Olena M. Gorodnya,
  • Mykhaylo V. Ruchko,
  • Glenn L. Wilson,
  • Mark N. Gillespie and
  • James C. Parker

22 August 2014

The mitochondrial targeted DNA repair enzyme, 8-oxoguanine DNA glycosylase 1, was previously reported to protect against mitochondrial DNA (mtDNA) damage and ventilator induced lung injury (VILI). In the present study we determined whether mitochondr...

  • Article
  • Open Access
13 Citations
8,444 Views
13 Pages

21 August 2014

Mitochondrial gene therapy and diagnosis have the potential to provide substantial medical benefits. However, the utility of this approach has not yet been realized because the technology available for mitochondrial gene delivery continues to be a bo...

  • Review
  • Open Access
34 Citations
10,095 Views
15 Pages

The Fungal Defensin Family Enlarged

  • Jiajia Wu,
  • Bin Gao and
  • Shunyi Zhu

18 August 2014

Fungi are an emerging source of peptide antibiotics. With the availability of a large number of model fungal genome sequences, we can expect that more and more fungal defensin-like peptides (fDLPs) will be discovered by sequence similarity search. He...

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Pharmaceuticals - ISSN 1424-8247