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Pharmaceuticals, Volume 7, Issue 8

August 2014 - 4 articles

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Articles (4)

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Article

9 Citations

6,799 Views

19 Pages

Mitochondrial Targeted Endonuclease III DNA Repair Enzyme Protects against Ventilator Induced Lung Injury in Mice

Masahiro Hashizume,
Marc Mouner,
Joshua M. Chouteau,
Olena M. Gorodnya,
Mykhaylo V. Ruchko,
Glenn L. Wilson,
Mark N. Gillespie and
James C. Parker

Pharmaceuticals2014, 7(8), 894-912;https://doi.org/10.3390/ph7080894

22 August 2014

The mitochondrial targeted DNA repair enzyme, 8-oxoguanine DNA glycosylase 1, was previously reported to protect against mitochondrial DNA (mtDNA) damage and ventilator induced lung injury (VILI). In the present study we determined whether mitochondr...

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Article

12 Citations

8,288 Views

13 Pages

Condensation of Plasmid DNA Enhances Mitochondrial Association in Skeletal Muscle Following Hydrodynamic Limb Vein Injection

Yukari Yasuzaki,
Yuma Yamada,
Yutaka Fukuda and
Hideyoshi Harashima

Pharmaceuticals2014, 7(8), 881-893;https://doi.org/10.3390/ph7080881

21 August 2014

Mitochondrial gene therapy and diagnosis have the potential to provide substantial medical benefits. However, the utility of this approach has not yet been realized because the technology available for mitochondrial gene delivery continues to be a bo...

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Review

34 Citations

9,835 Views

15 Pages

The Fungal Defensin Family Enlarged

Jiajia Wu,
Bin Gao and
Shunyi Zhu

Pharmaceuticals2014, 7(8), 866-880;https://doi.org/10.3390/ph7080866

18 August 2014

Fungi are an emerging source of peptide antibiotics. With the availability of a large number of model fungal genome sequences, we can expect that more and more fungal defensin-like peptides (fDLPs) will be discovered by sequence similarity search. He...

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Review

31 Citations

11,530 Views

16 Pages

Pain Management in Ambulatory Surgery—A Review

Jan G. Jakobsson

Pharmaceuticals2014, 7(8), 850-865;https://doi.org/10.3390/ph7080850

24 July 2014

Day surgery, coming to and leaving the hospital on the same day as surgery as well as ambulatory surgery, leaving hospital within twenty-three hours is increasingly being adopted. There are several potential benefits associated with the avoidance of...

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